Remarkable advances have occurred since the Series 3 Fascicle published in 1995 with paradigm shifts in every dimension of our understanding of lung tumors including clinical, radiologic, histopathologic, cytopathologic, immunohistochemical, molecular and therapeutic aspects. The molecular revolution leading to effective targeted therapies and breakthroughs in immunotherapy for lung cancer have led to novel approaches incorporating the concept of personalized medicine for patients who historically had little hope. These advances have strengthened the place of pathologists to play a central role in the multidisciplinary team that is now needed to properly diagnose and manage lung cancer patients.

Addresses one of the most difficult areas in surgical pathology, non-neoplastic disorders of the lower respiratory tract. Recognising the need for a multidisciplinary approach to the successful diagnosis of many of these diseases, a pulmonologist and two radiologists have been included as authors to supplement the pathology contributions. With their clinical and radiological expertise, the authors have greatly enhanced the pathology descriptions resulting in a book of almost 1000 pages, with a total of 1,185 colour and 284 black and white images, including pathology as well as radiology illustrations. When appropriate, the importance of clinical, radiological, and pathologic correlation is emphasised. The radiology images include characteristic manifestations on chest radiography and high-resolution computed tomography. This reference will be helpful to clinicians, radiologists, and pathologists seeking a better understanding of this difficult subject.