In this edited collection we commemorate the 60th birthday of Prof. Christopher Byrnes and the retirement of Prof. Anders Lindquist from the Chair of Optimization and Systems Theory at KTH. These papers were presented in part at a 2009 workshop in KTH, Stockholm, honoring the lifetime contributions of Professors Byrnes and Lindquist in various fields of applied mathematics.

This book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials.

Recent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechanisms involved in neurological injury and of various translational and clinical research aimed at harnessing those mechanisms for better patient outcomes.

This book is mainly focused on the climate change in Southeast Asia and its adjacent regions. It summarizes results from recent scientific research based on observational analysis, data diagnosis, theoretical analysis, and model simulations. The book covers the following research areas: (1) characteristics and mechanisms of spring-summer atmospheric circulation systems, (2) ocean-atmosphere-land interaction and climate variability, (3) climate effect of the Tibetan Plateau, (4) attribution of regional climate change and feedback/impact of regional climate on the global climate, and (5) seasonal-to-subseasonal climate prediction. It is anticipated that the book provides useful information for enhancing our understanding of the change in climate over Southeast Asia and the adjacent regions.

Recent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechanisms involved in neurological injury and of various translational and clinical research aimed at harnessing those mechanisms for better patient outcomes.

In this edited collection we commemorate the 60th birthday of Prof. Christopher Byrnes and the retirement of Prof. Anders Lindquist from the Chair of Optimization and Systems Theory at KTH. These papers were presented in part at a 2009 workshop in KTH, Stockholm, honoring the lifetime contributions of Professors Byrnes and Lindquist in various fields of applied mathematics.

This book is mainly focused on the climate change in Southeast Asia and its adjacent regions. It summarizes results from recent scientific research based on observational analysis, data diagnosis, theoretical analysis, and model simulations. The book covers the following research areas: (1) characteristics and mechanisms of spring-summer atmospheric circulation systems, (2) ocean-atmosphere-land interaction and climate variability, (3) climate effect of the Tibetan Plateau, (4) attribution of regional climate change and feedback/impact of regional climate on the global climate, and (5) seasonal-to-subseasonal climate prediction. It is anticipated that the book provides useful information for enhancing our understanding of the change in climate over Southeast Asia and the adjacent regions.

This book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials.

Gas/particle mass transfer process plays an important role in determining aerosol mass concentrations and shaping aerosol size distribution. Its treatments in three dimensional (3-D) Air Quality Models (AQMs), however, are largely uncertain. In this thesis work, the gas/particle mass transfer approaches in an aerosol module are improved and evaluated to identify an accurate yet computationally efficient approach for use in 3-D AQMs. The aerosol module with the improved gas/particle mass transfer approaches has been incorporated into a state-of-science air quality forecasting (AQF) system. The resulted modeling system has been applied in many cases to investigate the air pollution issues in the United States. Using the improved air quality modeling system, the prediction of air quality under many circumstances is shown significantly improved. Such improvement is a substantial contribution to the development of next generation air quality numerical models.