This book provides the reader with a comprehensive view of analytical methods for nanotoxicology studies. After an introduction to nanomaterials and toxicological studies, the book discusses various characterization methods of nanomaterials and continues with the detection of nanoparticles in vivo as well as in vitro. A variety of techniques in molecular toxicology of nanomaterials is presented, followed by a detailed explanation of interaction between nanoparticles and biomacromolecules, including the structure-toxicity relationships of nanomaterials. Finally, the book concludes with the advantages and challenges of the analytical methods for nanotoxicology.

The book discusses in a detailed manner various nanomaterials used for biomedical applications, including clinical applications, diagnosis and tissue engineering. After the presentation of an overview of biomedical nanomaterials, including their classification and applications, the first part of the book is devoted to biomedical nanomaterials for therapy applications. For example, polymer micelles, dendrimers, polymer-drug conjugates as well as antibody-drug conjugates are discussed with respect to their cancer drug delivery properties. The next parts discuss biomedical nanomaterials that are used for imaging, diagnosis and sensors, as well as for tissue engineering. In the final section, the safety of biomedical nanomaterials is elaborated.

Dimensional metrology is an essential part of modern manufacturing technologies, but the basic theories and measurement methods are no longer sufficient for today's digitized systems. The information exchange between the software components of a dimensional metrology system not only costs a great deal of money, but also causes the entire system to lose data integrity. Information Modeling for Interoperable Dimensional Metrology analyzes interoperability issues in dimensional metrology systems and describes information modeling techniques. It discusses new approaches and data models for solving interoperability problems, as well as introducing process activities, existing and emerging data models, and the key technologies of dimensional metrology systems. Written for researchers in industry and academia, as well as advanced undergraduate and postgraduate students, this book gives both an overview and an in-depth understanding of complete dimensional metrology systems. By covering in detail the theory and main content, techniques, and methods used in dimensional metrology systems, Information Modeling for Interoperable Dimensional Metrology enables readers to solve real-world dimensional measurement problems in modern dimensional metrology practices.

Dimensional metrology is an essential part of modern manufacturing technologies, but the basic theories and measurement methods are no longer sufficient for today's digitized systems. The information exchange between the software components of a dimensional metrology system not only costs a great deal of money, but also causes the entire system to lose data integrity.

"Information Modeling for Interoperable Dimensional Metrology" analyzes interoperability issues in dimensional metrology systems and describes information modeling techniques. It discusses new approaches and data models for solving interoperability problems, as well as introducing process activities, existing and emerging data models, and the key technologies of dimensional metrology systems.

Written for researchers in industry and academia, as well as advanced undergraduate and postgraduate students, this book gives both an overview and an in-depth understanding of complete dimensional metrology systems. By covering in detail the theory and main content, techniques, and methods used in dimensional metrology systems, "Information Modeling for Interoperable Dimensional Metrology" enables readers to solve real-world dimensional measurement problems in modern dimensional metrology practices. "

STRUCTURAL RELIABILITY Discover a new and innovative approach to structural reliability from two authoritative and accomplished authors The subject of structural reliability, which deals with the problems of evaluating the safety and risk posed by a wide variety of structures, has grown rapidly over the last four decades. And while the First-Order Reliability Method is principally used by most textbooks on this subject, other approaches have identified some of the limitations of that method. In Structural Reliability: Approaches from Perspectives of Statistical Moments, accomplished engineers and authors Yan-Gang Zhao and Dr. Zhao-Hui Lu, deliver a concise and insightful exploration of an alternative and innovative approach to structural reliability. Called the Methods of Moment, the authors' approach is based on the information of statistical moments of basic random variables and the performance function. The Methods of Moment approach facilitates -structural reliability analysis and reliability-based design and can be extended to other engineering disciplines, yielding further insights into challenging problems involving -randomness. Readers will also benefit from the inclusion of: A thorough introduction to the measures of structural safety, including uncertainties in structural design, deterministic measures of safety, and probabilistic measures of safety An exploration of the fundamentals of structural reliability theory, including the performance function and failure probability A practical discussion of moment evaluation for performance functions, including moment computation for both explicit and implicit performance functions A concise treatment of direct methods of moment, including the third- and fourth-moment reliability methods Perfect for professors, researchers, and graduate students in civil engineering, Structural Reliability: Approaches from Perspectives of Statistical Moments will also earn a place in the libraries of professionals and students working or studying in mechanical engineering, aerospace and aeronautics engineering, marine and offshore engineering, ship engineering, and applied mechanics.

This book presents a collection of 38 position and research papers surveying the future landscape of research in distributed computing, written by the participants of the Workshop on Future Directions in Distributed Computing, held in Bertinoro, Italy in June 2002. The papers are grouped into four topical sections. The first deals with foundations of distributed computing. The second section surveys research issues in novel communication and network services. The third section is about data, file services, coherence, and replication in network computing. The last section deals with system and application issues. The book also includes two papers presenting insights into technological and social processes that are part of the development of the distributed computing technology. All in all, the book contains a plethora of research topics that are targets of future research or that are already being addressed by forward-looking research in distributed computing. The book was written to be a source of inspiration for researchers and a source of motivation for graduate students interested in entering the exciting research field of distributed computing.

This book reviews the cutting-edge significant research in the field of smart light-responsive materials based on azobenzene polymers and liquid crystals. Emphasis is placed on the discovery of new phenomena from the past 5 years, their underlying mechanisms, new functionalities, and properties achieved through rational design. Edited by leading authorities in the field, Zhao and Ikeda, the chapters are authored by an internationally-recognized team of experts from North America, Europe, and Asia. Smart Light-Responsive Materials will serve to catalyze new research that will lead this field over the next 5-10 years.