The education division is a prominent part of the public health profession. It focuses on educating individuals and communities to promote health and prevent disease. The educators are drawn from a diverse range of disciplines and defined as professionally prepared individuals who serve in a variety of roles using appropriate educational strategies and methods to facilitate the development of policies, procedures, interventions, and systems conducive to the health of individuals.This unique volume in the Global Science Education Series describes some of the challenges faced by this profession in helping the audience to understand public health and solve health issues. Key Features: Aids researchers in designing an evaluation study in CPE for health professions and related fields Presents data on how public health practice comprises of individuals working together toward promoting population health Covers continuing professional education in the US and how it can be adopted globally Discusses the Kirkpatrick's four-level evaluation model at length Demonstrates how questionnaires are preferable in evaluating CPE programs due to their cost effectiveness and being user friendly

There has been a global rise in the incidence of chronic illnesses, which may be partially attributed to the lengthening of the average human lifespan. Functional foods and nutraceuticals have a potential role to play in the development and maintenance of health. They can assist the body in its battle against inflammation and chronic illnesses. Molecular Mechanisms of Action of Functional Foods and Nutraceuticals for Chronic Diseases addresses the effects and mechanism of functional foods in relation to chronic diseases such as obesity, cardiovascular diseases, diabetes, cancer, etc. This volume, like the companion Applications of Functional Foods and Nutraceuticals for Chronic Diseases, inspires new thought processes and a paradigm shift in research and development. Key Features: Discusses the molecular mechanism of action, the range of toxicities exerted by these food components for functional foods for addressing chronic conditions Enhances scientists and industrial personnel knowledge of functional foods and in the management of chronic diseases Presents research on the role of functional foods/nutraceuticals in preventing and treating chronic diseases through epigenetic modulation. Explores various subjects such as epigenetics, immunological, metabolic, technological and neurodenerative aspects affected by functional foods in chronic diseases The world's leading wellness centers for chronic diseases are using functional foods and nutraceuticals in their practice and discovering their useful applications, and this second of two related books is another great reference for practitioners, scientists, and clinicians in the management of chronic diseases. Contributors hail from different geographical locations around the world and have many years of research and scholarly experience in functional foods, nutraceuticals, and biology.

Nutrition remains the key for successful disease treatments, in addition to the various evolved medical treatments across the world. The treatment outcome improves to a better extent with degree of nourishment of the patients. Therapeutic Nutrition in Ayurveda (TNA) has categorized system-wise diseases and discussed the nutrition with references from Ayurveda classics to the publications from indexed journals in today’s world. This book emerges as a pilot project to discuss the clinical experiences directly and the concept of Nutra-vigilance, by the experienced authors of respective specialties like hepatology, neurology, dermatology, ophthalmology, oncology, cardiology, gynecology and so on. It broadly discusses Diet & Nutrition based on 12 different groups of diet in Ayurveda. Nutrition has been widely discussed for every disease dynamically in Ayurveda, with details of exclusion and inclusion of foods over a stipulated period or entire duration of treatment. Key Features: Presents system-wise and disease-wise Therapeutic Nutrition Includes clinical experience of physicians on therapeutic nutrition Contains interdisciplinary discussion on therapeutic nutrition with integrated approach The Integration of traditional & conventional health systems along with the multi-disciplinary approach is the emerging trend for inclusive health care in coming decades. This book serves as a handy guide for healthcare professionals across the continents providing interdisciplinary correlations on nutrition.

This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges

A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles. This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases.

Nutrition remains the key for successful disease treatments, in addition to the various evolved medical treatments across the world. The treatment outcome improves to a better extent with degree of nourishment of the patients. Therapeutic Nutrition in Ayurveda (TNA) has categorized system-wise diseases and discussed the nutrition with references from Ayurveda classics to the publications from indexed journals in today’s world. This book emerges as a pilot project to discuss the clinical experiences directly and the concept of Nutra-vigilance, by the experienced authors of respective specialties like hepatology, neurology, dermatology, ophthalmology, oncology, cardiology, gynecology and so on. It broadly discusses Diet & Nutrition based on 12 different groups of diet in Ayurveda. Nutrition has been widely discussed for every disease dynamically in Ayurveda, with details of exclusion and inclusion of foods over a stipulated period or entire duration of treatment. Key Features: Presents system-wise and disease-wise Therapeutic Nutrition Includes clinical experience of physicians on therapeutic nutrition Contains interdisciplinary discussion on therapeutic nutrition with integrated approach The Integration of traditional & conventional health systems along with the multi-disciplinary approach is the emerging trend for inclusive health care in coming decades. This book serves as a handy guide for healthcare professionals across the continents providing interdisciplinary correlations on nutrition.

Discusses artificial intelligence and ethics, the challenges and opportunities Presents the issue of reliability in the emergence of synthetic life, 5G networks, intermingling of human artificial intelligence, nano-robots, and cyber security tools Ethical responsibility and reasoning for using AI in Big Data Addresses practicing medicine and ethical issues when applying artificial intelligence

This book provides an overview of nanoparticle production methods, scale-up issues drawing attention to industrial applicability, and addresses their successful applications for commercial use. There is a need for a reference book which will address various aspects of recent progress in the methods of development of nanoparticles with a focus on polymeric and lipid nanoparticles, their scale-up techniques, and challenges in their commercialization. There is no consolidated reference book that discusses the emerging technologies for nanoparticle manufacturing. This book focuses on the following major aspects of emerging technologies for nano particle manufacturing. I. Introduction and Biomedical Applications of NanoparticlesII. Polymeric Nanoparticles III. Lipid NanoparticlesIV. Metallic Nanoparticles V. Quality Control for NanoparticlesVI. Challenges in Scale-Up Production of Nanoparticles VII. Injectable Nanosystems VIII. Future Directions and ChallengesLeading scientists are selected as chapter authors who have contributed significantly in this field and they focus more on emerging technologies for nanoparticle manufacturing, future directions, and challenges.

Phytochemicals are receiving increasing attention due to their observed nutritional and health-promoting effects in numerous food applications. As plant secondary metabolites with bioactive properties, they may provide desirable health benefits beyond basic nutrition to reduce chronic disease conditions. Their importance in nutrition and health cannot be overstated as it has generated so much interest and studies focused on elucidating their roles has produced so many outstanding results. Plant phytochemicals are readily used in alternative medicine in South East Asia especially, in China and India and they are becoming widely acceptable worldwide. However, very little is still known about the phytochemicals despite these intense research efforts because of their diverse biological and chemical nature. In this newest addition to the series, Nutraceuticals: Basic Research and Clinical Applications, Food Plant Phytochemicals and Bioactive Compounds in Nutrition and health provides a comprehensive review of the current state of knowledge in the field of bioactive plant phytochemical compounds, their food sources, bioactivities, bioavailability, extraction, production, and applications. Experts in the field discuss various bioactivities of the notable and promising plant phytochemicals of significance in nutrition and health, e.g., lowering of CVD, hypertension, cholesterol, diabetes, obesity, inflammation, cancer, oxidative stress, neurodegenerative diseases and a host of other chronic disease conditions. Key Features: · Describes the various nutritional and bioactive significances of notable and promising plant phytochemicals of significance in nutritional and medical research and their food and/or plant sources. · Includes various approaches for the quantification, extraction and production of the notable and promising phytochemical compounds in nutrition and health. · Examines the challenges and promises of plant phytochemical as ingredients for the development of functional foods and nutraceuticals as well as their use in alternative medicine. · Discusses regulatory issues regarding plant phytochemicals, especially as it pertains to their health claims and use

This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.

Addresses various aspects of recent progress in the development of all types of tumor-responsive and site-specific delivery platforms together with the range of related chemistries involved. A timely volume as global research in oncology is moving towards more biochemical signal-based and cell environment-inspired therapeutic strategies. Furthermore, the book emphasizes the need to explore various characterization techniques for specific stimuli-responsive nanoplatforms, toxicological and regulatory aspects. Features Focused, comprehensive volume providing a different angle on theranostics in cancer intervention. A timely volume as global research in oncology is moving towards more biochemical signal-based and cell environment-inspired therapeutic strategies. Targets not only the multifunctionality of the nanosystems but provides a comprehensive overview of niche technical aspects. Given the chemistries presented here, it provides both early-career and experienced readers with strategies from leading authorities in the field globally.

Explains various factors related to anxiety and anxiety related disorders including pathophysiological and pharmacological factors Discusses the pharmacology behind anxiety and related disorders Explores the role of gut microbiota and its relationship with anxiety and related disorders Describes different nutraceuticals and classes of nutraceuticals which can be useful to treat anxiety and related disorders

The proposed book is envisioned for the nascent and entry-level researchers who are interested to work in the field of drug delivery and its applications specifically for macrophage targeting. Macrophages have gained substantial attention as therapeutic targets for drug delivery considering their major role in health and regulation of diseases. Macrophage-targeted therapeutics have now added significant value to the lives and quality of life of patients, without undue adverse effects in multiple disease settings. We anticipate examining and integrating the role of macrophages in the instigation and advancement of various diseases. The major focus of the book is on recent advancements in various targeting strategies using delivery systems or nanocarriers followed by application of these nanocarriers for the treatment of macrophage associated disorders. Macrophage Targeted Delivery Systems is primarily targeted to Pharmaceutical Industry & Academia, Medical & Pharmaceutical Professionals, Undergraduate & Post graduate students and Research Scholars, Ph.D, post docs working in the field of medical and pharmaceutical sciences.

Bioactive peptides have been receiving attention recently due to their applications as health-promoting agents. Derived from food proteins and other natural sources, they exhibit various beneficial effects such as preventing diseases or modulating physiological systems once absorbed. As the market for nutraceuticals and functional foods continues to expand, consumer interest has also grown and there are many common foods that have shown an abundance of bioactive peptides, including dairy products, cereal, legumes, meat, and numerous other sources. In this newest addition to the series Nutraceuticals: Basic Research and Clinical Applications, Bioactive Peptides: Production, Bioavailability, Health Potential, and Regulatory Issues provides a comprehensive review of the current state of knowledge in the field of food protein hydrolysates and bioactive peptides, their food sources, bioavailability, production, applications, functionalities, health potentials, and regulatory issues governing their use. Features Discusses different methodologies employed for scaling up bioactive peptides commercially Provides information on optimizing the production process Explains various bioactive properties exerted by different types of bioactive peptides Explores the application of metabolomics to the study of bioactive peptides With over 20 chapters written by established subject matter experts in their field, this book provides timely information and discusses the latest developments of bioactive peptides. It will be useful for researchers, academics, and industry experts, and can serve as an excellent resource for anyone interested in enhancing their knowledge in the field of bioactive peptides.

The nuclear factor erythroid 2-related factor 2 (Nrf2) was described as a master regulator of the cellular antioxidant response. Moreover, many critical biological functions linked to cell viability, metabolism, autophagy, inflammation, immunity, and differentiation have been attributed to Nrf2, which regulates over 600 genes. It is well known that oxidative stress, which Nrf2 can ameliorate, plays a key role in many pathologic processes such as aging, obesity, diabetes, cancer, and neurodegenerative diseases. Flavonoids, on the other hand, through their ability to activate and upregulate Nrf2, can have anti-oxidative, anti-inflammatory, anti-mutagenic, and anti-carcinogenic properties. Flavonoids are an essential ingredient in nutraceuticals, functional foods, and pharmaceuticals. The present book Flavonoids and Anti-Aging: The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2 focuses on the interaction between Nrf2 and flavonoids and their applications in various conditions such as aging, osteoporosis, cardiovascular diseases, and neurodegenerative disease and many other areas. Key Features: Focuses on the mechanisms and use of flavonoids in activating Nrf2 as an anti-aging and "WELLNESS" molecule Provides a specific approach to flavonoid activation of Nrf2 and its implications in aging and various disease conditions and its applications as nutraceuticals Presents flavonoid-based functional foods Discusses the flavonoid nutraceuticals market and future trends Written by experts in the field, this book provides a unique approach to understanding the flavonoid activation of the transcription factor Nrf2, which is responsible for many different disease conditions due to increased reactive oxidative species in the body caused by some physiological triggers.

This book addresses the recent trends and clinical research being reported in last 5 to 10 years in the field of nasal drug delivery systems. In recent years, interest in using nasal passage as drug absorption site has received increased attention from formulation scientists. Nasal passages, even though a small surface area of the body as compared to other absorption passage such as Gastrointestinal tract or skin,  show significant possibility for drug absorption at a quicker rate. There is also a possibility of delivering drugs to the brain using this passage and targeting drugs through the nasal passage. The book has 19 chapters addressing various aspects of nasal drug delivery systems such as an overview of anatomy and physiology of the nasal passage from a drug delivery point of view to global market opportunities for nasal drug delivery. In between, it addresses various aspects of nasal drug delivery. There are very few titles exclusively dedicated to nasal drug delivery, covering the formulation and developmental aspects, and addressing the challenges and solutions. The primary audiences for the book are graduate students in field of medicine, pharmacy and also various researchers who are working in the area of nasal drug delivery in addition to students who are specializing in field of medicine in ENT. This book provides comprehensive information on all the aspects related to the nasal drug delivery of various drug molecules.

In a finished nutraceutical product, flavors play an integral role. Flavor Development for Functional Foods and Nutraceuticals is about the crucial role added flavors play in any nutraceutical product. It describes the various extraction techniques that are being adopted for manufacturing flavors from natural raw materials. Yield and retention of aromatic components during several extraction methods and flavor encapsulation techniques for thermal degradable food components are discussed. Advanced methods of flavor extraction techniques like supercritical C02 extraction are emphasized. The safety and quality aspects of flavor incorporation in food processing industries are reviewed with respect to international regulations. The importance of flavor in the nutraceuticals industry is also discussed. In addition, the book stresses the functional value and organoleptic acceptability towards product optimization/formulation. Features: Explains how flavors play an integral role in a finished nutraceutical product Describes the various extraction techniques that are being adopted for manufacturing flavors from natural raw materials Covers flavor encapsulation techniques for thermal degradable food components Provides an introduction to the history of how some natural flavor ingredients, botanicals, and extracts were used in ancient times in Ayurveda and herbal medicine This is an ideal reference book for the flavor chemists, food scientists, nutraceutical formulators, and students and academicians who are working in the area of nutraceutical, supplement, and functional food development and provides very useful information to help them select appropriate flavors for their products. Also available in the Nutraceuticals: Basic Research/Clinical Applications Series: Flavors for Nutraceuticals and Functional Foods, edited by M. Selvamuthukumaran and Yashwant Pathak (ISBN: 978-1-1380-6417-1) Antioxidant Nutraceuticals: Preventive and Healthcare Applications, edited by Chuanhai Cao, Sarvadaman Pathak, Kiran Patil (ISBN 978-1-4987-3703-6) Food By-product Based Functional Food Powders, edited by OEzlem Tokusoglu (ISBN 978-1-4822-2437-5)

Provides the latest information on trends in this fast-growing market Focuses on the six marine taxa that offer the most exciting potential Gives practical guidance to anyone wishing to enter this sector

Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the safety and effectiveness standards of a new drug in accordance. This book comprises a complete start-to-end process from drug-idea conception, to drug development process. Key Features: Provides a complete compendium for botanical drug products Describes what BDP is and how it differs from Pharma, Biopharma, and Nutraceuticals Compiles all critical regulatory steps in a variety of countries Discusses clinical trial management for BDP development and how it differs from conventional chemical-based drugs and biopharmaceutics

Although health claims for nutraceuticals range from the fantastic to the sublime, most of these claims are based on cell culture studies and have not been validated in humans, making them inadequate for public health recommendations. Focusing on human population-based research (epidemiology studies), Nutraceuticals and Health: Review of Human Evidence explores the role of nutraceuticals in human health, disease prevention, health promotion, and as an adjunct to disease treatment. The editors and their team of recognized experts deliver a comprehensive scientific review of the latest research. The book opens with a general background of nutraceuticals and human health, then covers health and disease areas such as cancer, lipidermia and cardiovascular disease, metabolic syndrome with obesity, diabetes and hypertension, respiratory health, the gut microbiome, and cognitive decline. It then concludes by addressing the methodological issues that must be addressed in the conduct of epidemiological research on nutraceuticals in health and disease. Although nutraceuticals hold significant promise in alleviating the suffering from disease, for this potential to be fulfilled, much more research is needed to document safety and disease risks in humans. Addressing important knowledge gaps, the book includes cutting-edge summaries that highlight both the biological and epidemiological findings of relevant studies of nutraceuticals in health and disease. Taking an unusual, yet crucial epidemiological focus, it examines whether, and what kinds of, evidence exist to support a role for nutraceuticals in disease risk, prevention, and treatment.

Although health claims for nutraceuticals range from the fantastic to the sublime, most of these claims are based on cell culture studies and have not been validated in humans, making them inadequate for public health recommendations. Focusing on human population-based research (epidemiology studies), Nutraceuticals and Health: Review of Human Evidence explores the role of nutraceuticals in human health, disease prevention, health promotion, and as an adjunct to disease treatment. The editors and their team of recognized experts deliver a comprehensive scientific review of the latest research. The book opens with a general background of nutraceuticals and human health, then covers health and disease areas such as cancer, lipidermia and cardiovascular disease, metabolic syndrome with obesity, diabetes and hypertension, respiratory health, the gut microbiome, and cognitive decline. It then concludes by addressing the methodological issues that must be addressed in the conduct of epidemiological research on nutraceuticals in health and disease. Although nutraceuticals hold significant promise in alleviating the suffering from disease, for this potential to be fulfilled, much more research is needed to document safety and disease risks in humans. Addressing important knowledge gaps, the book includes cutting-edge summaries that highlight both the biological and epidemiological findings of relevant studies of nutraceuticals in health and disease. Taking an unusual, yet crucial epidemiological focus, it examines whether, and what kinds of, evidence exist to support a role for nutraceuticals in disease risk, prevention, and treatment.

Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the safety and effectiveness standards of a new drug in accordance. This book comprises a complete start-to-end process from drug-idea conception, to drug development process. Key Features: Provides a complete compendium for botanical drug products Describes what BDP is and how it differs from Pharma, Biopharma, and Nutraceuticals Compiles all critical regulatory steps in a variety of countries Discusses clinical trial management for BDP development and how it differs from conventional chemical-based drugs and biopharmaceutics

This book provides an overview of nanoparticle production methods, scale-up issues drawing attention to industrial applicability, and addresses their successful applications for commercial use. There is a need for a reference book which will address various aspects of recent progress in the methods of development of nanoparticles with a focus on polymeric and lipid nanoparticles, their scale-up techniques, and challenges in their commercialization. There is no consolidated reference book that discusses the emerging technologies for nanoparticle manufacturing. This book focuses on the following major aspects of emerging technologies for nano particle manufacturing. I. Introduction and Biomedical Applications of NanoparticlesII. Polymeric Nanoparticles III. Lipid NanoparticlesIV. Metallic Nanoparticles V. Quality Control for NanoparticlesVI. Challenges in Scale-Up Production of Nanoparticles VII. Injectable Nanosystems VIII. Future Directions and ChallengesLeading scientists are selected as chapter authors who have contributed significantly in this field and they focus more on emerging technologies for nanoparticle manufacturing, future directions, and challenges.

This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.