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This volume assembles a broad spectrum of methods used in long
non-coding RNAs (lncRNA) research, ranging from computational
annotation of lncRNA genes to molecular and cellular analyses of
the function of individual lncRNA. Long Non-Coding RNAs: Methods
and Protocols also discusses methods used to study circular RNAs
and RNA splicing, as well as influential findings on lncRNA in
human diseases. Written in the highly successful Methods in
Molecular Biology series format, chapters include introductions to
their respective topics, lists of the necessary materials and
reagents, step-by-step, readily reproducible laboratory protocols,
and tips on troubleshooting and avoiding known pitfalls. Thorough
and cutting-edge, Long Non-Coding RNAs: Methods and Protocols is a
must-have for molecular biologists, cell and developmental
biologists, specialists who conduct disease-oriented research, and
bioinformatics experts who seek a better understanding on lncRNA
expression and function by computational analysis of the massive
sequencing data that are rapidly accumulating in recent years.
This volume assembles a broad spectrum of methods used in long
non-coding RNAs (lncRNA) research, ranging from computational
annotation of lncRNA genes to molecular and cellular analyses of
the function of individual lncRNA. Long Non-Coding RNAs: Methods
and Protocols also discusses methods used to study circular RNAs
and RNA splicing, as well as influential findings on lncRNA in
human diseases. Written in the highly successful Methods in
Molecular Biology series format, chapters include introductions to
their respective topics, lists of the necessary materials and
reagents, step-by-step, readily reproducible laboratory protocols,
and tips on troubleshooting and avoiding known pitfalls. Thorough
and cutting-edge, Long Non-Coding RNAs: Methods and Protocols is a
must-have for molecular biologists, cell and developmental
biologists, specialists who conduct disease-oriented research, and
bioinformatics experts who seek a better understanding on lncRNA
expression and function by computational analysis of the massive
sequencing data that are rapidly accumulating in recent years.
This book analyzes China's transformative political power in
today's world while simultaneously addressing global issues and the
reformation of world institutions. China has become known as the
world's first factory and trading power, but more knowledge on
China's rise is necessary to understand the world of today and the
future. The main question is where China's rise is headed and how
this affects the increasingly connected world that faces problems
that no state can effectively address on its own. This book
analyzes both sides of the coin, that is, the problems of a world
scale and the change of the world political order. China is among
the major actors for global issues such as mitigating climate
warming, controlling weapons of mass destruction, combating
economic inequality and underdevelopment, and improving health for
all. In the current setting of the new world order, all countries
and especially world powers develop a general blueprint for the
future, as cultural and material conditions of the present world
are very different from the past. Under such conditions, China
faces a review of its bilateral and regional strategies, as well as
its position and actions in world institutions that have the
mission of forming policy responses to issues of a global scale.
This book, therefore, provides insight into China's view of world
problems and the future world order. It is a must-read for
everybody interested in a better understanding of China's role in
today's world and the global power shift.
A resource-based theory study is one of the most widely accepted
theoretical perspectives in explaining competitive capabilities in
relation to capability and sustainable competitive advantage. For
example, the study tends to be designed as a conceptual framework
for explaining the conditions under which firms may achieve a
sustainable competitive advantage through capabilities which are
valuable, and non-substitutable. Accordingly, the present study
interconnects the theoretical relationship between the capabilities
and competitive advantage of the resources-physical, human, and
technology, which provide conditions under which firms may achieve
a sustainable competitive advantage from the dynamic capabilities.
The new insights suggest that firm's three dynamic competitive
capabilities are considered as complementarities when one
capability enhances the value and effect of another capability. The
primary result of this study is towards the complementarities, in
addition to individual influences of the resources, of these
capabilities, which lead to the predictions of its Customer
Relationship Management advantage that prepares and assures towards
a sustainable advantage objective.
China, following its radical economic reform has developed rapidly
in recent decades with nearly double digit annual economic growth
rates. China has experienced a major transformation in its
transition from centrally planned economy to a developed and
relatively well functioning market economy. This has been
facilitated through a vision, strategy, planning, management and
skilful implementation of such comprehensive reform program. The
planning and implementation of the policy of reforming the economy
has affected every aspect of life in China. It has implied
organisational reforms and changes in production technology. The
changes have required enormous amount of resources in various forms
particularly in the energy sector, education and different public
and private infrastructures. This book provides an up-to-date and
in depth analysis of five factors crucial to the success of the
policy and current state of the economy. These include: economic
growth, bilateral trade relations, science and technology, flow of
foreign direct investment and income inequality. They all together
provide a comprehensive picture of the recent developments in the
Chinese economy and its path of reform. The development has been a
great source of admiration around the world.
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