This comprehensive compendium designs deep neural network models and systems for intelligent analysis of fundus imaging. In response to several blinding fundus diseases such as Retinopathy of Prematurity (ROP), Diabetic Retinopathy (DR) and Macular Edema (ME), different image acquisition devices and fundus image analysis tasks are elaborated.From the actual fundus disease analysis tasks, various deep neural network models and experimental results are constructed and analyzed. For each task, an actual system for clinical application is developed.This useful reference text provides theoretical and experimental reference basis for AI researchers, system engineers of intelligent medicine and ophthalmologists.

The food industry has seen many changes over the last several decades - new technologies have been introduced into the way we cook, manufacture, and present food products to consumers. Digital gastronomy, which combines new computational abilities such as three-dimensional (3D) printing with traditional food preparation, has allowed consumers to design and manufacture food with personalized shapes, colours, textures, and even nutrition. In addition to the personalization of food, 3D printing of food has other advantages such as promoting automation in food preparation and food sustainability through 3D-printed cell-based meats and alternative proteins. Entire meals can be constructed just by 3D food printing alone.In this textbook, the background, principles, commercial food printers, materials, regulations, business development, as well as the emerging technologies and future outlook of 3D food printing are explored. In terms of 3D-printed materials, four main classes are reviewed: namely, desserts / snacks (comprising dairy products, chocolate, sugars, and dough), fruits / vegetables, meats /alternative proteins, and pharmaceuticals / nutraceuticals.This textbook has been written to offer readers keen to learn more about 3D food printing in terms of concepts, processes, applications, and developments of 3D food printing. No prior knowledge is required. At the end of each chapter, a set of problems offers undergraduate and postgraduate students practice on the main ideas discussed within the chapter. For tertiary-level lecturers and university professors, the topic on 3D food printing can be associated to other subjects in food and nutrition, pharmaceutical and nutraceutical sciences, and food engineering.

The food industry has seen many changes over the last several decades - new technologies have been introduced into the way we cook, manufacture, and present food products to consumers. Digital gastronomy, which combines new computational abilities such as three-dimensional (3D) printing with traditional food preparation, has allowed consumers to design and manufacture food with personalized shapes, colours, textures, and even nutrition. In addition to the personalization of food, 3D printing of food has other advantages such as promoting automation in food preparation and food sustainability through 3D-printed cell-based meats and alternative proteins. Entire meals can be constructed just by 3D food printing alone.In this textbook, the background, principles, commercial food printers, materials, regulations, business development, as well as the emerging technologies and future outlook of 3D food printing are explored. In terms of 3D-printed materials, four main classes are reviewed: namely, desserts / snacks (comprising dairy products, chocolate, sugars, and dough), fruits / vegetables, meats /alternative proteins, and pharmaceuticals / nutraceuticals.This textbook has been written to offer readers keen to learn more about 3D food printing in terms of concepts, processes, applications, and developments of 3D food printing. No prior knowledge is required. At the end of each chapter, a set of problems offers undergraduate and postgraduate students practice on the main ideas discussed within the chapter. For tertiary-level lecturers and university professors, the topic on 3D food printing can be associated to other subjects in food and nutrition, pharmaceutical and nutraceutical sciences, and food engineering.

This book presents state-of-the-art solution methods and applications of stochastic optimal control. It is a collection of extended papers discussed at the traditional Liverpool workshop on controlled stochastic processes with participants from both the east and the west. New problems are formulated, and progresses of ongoing research are reported. Topics covered in this book include theoretical results and numerical methods for Markov and semi-Markov decision processes, optimal stopping of Markov processes, stochastic games, problems with partial information, optimal filtering, robust control, Q-learning, and self-organizing algorithms. Real-life case studies and applications, e.g., queueing systems, forest management, control of water resources, marketing science, and healthcare, are presented. Scientific researchers and postgraduate students interested in stochastic optimal control,- as well as practitioners will find this book appealing and a valuable reference.

This book aims to portray ancient civilizations and the development of early states in China and the rest of the world during the Liangzhu period. From a global perspective, it describes the ancient Egyptian, Sumerian and Harappan civilizations, as well as lesser-known civilizations such as the Cyclades and Caral, underscoring the similarities and differences between their central settlements, capitals and material cultural remains. As for the national aspect, the book mainly explores the development process of east Asian civilization as represented by Chinese civilization and probes into the evolution of the Liangzhu, Dawenkou and Qujialing civilizations four to five thousand years ago in a search for the origins of Chinese civilization.

This book offers a systematic and rigorous treatment of continuous-time Markov decision processes, covering both theory and possible applications to queueing systems, epidemiology, finance, and other fields. Unlike most books on the subject, much attention is paid to problems with functional constraints and the realizability of strategies. Three major methods of investigations are presented, based on dynamic programming, linear programming, and reduction to discrete-time problems. Although the main focus is on models with total (discounted or undiscounted) cost criteria, models with average cost criteria and with impulsive controls are also discussed in depth. The book is self-contained. A separate chapter is devoted to Markov pure jump processes and the appendices collect the requisite background on real analysis and applied probability. All the statements in the main text are proved in detail. Researchers and graduate students in applied probability, operational research, statistics and engineering will find this monograph interesting, useful and valuable.

Perception of human beings has evolved from natural biosensor to powerful sensors and sensor networks. In sensor networks, trillions of devices are interconnected and sense a broad spectrum of contexts for human beings, laying the foundation of Internet of Things (IoT). However, sensor technologies have several limitations relating to deployment cost and usability, which render them unacceptable for practical use. Consequently, the pursuit of convenience in human perception necessitates a wireless, sensorless and contactless sensing paradigm. Recent decades have witnessed rapid developments in wireless sensing technologies, in which sensors detect wireless signals (such as acoustic, light, and radio frequency) originally designed for data transmission or lighting. By analyzing the signal measurements on the receiver end, channel characteristics can be obtained to convey the sensing results. Currently, significant effort is being devoted to employing the ambient Wi-Fi, RFID, Bluetooth, ZigBee, and television signals for smart wireless sensing, eliminating the need for dedicated sensors and promoting the prospect of the Artificial Intelligence of Things (AIoT). This book provides a comprehensive and in-depth discussion of wireless sensing technologies. Specifically, with a particular focus on Wi-Fi-based sensing for understanding human behavior, it adopts a top-down approach to introduce three key topics: human detection, localization, and activity recognition. Presenting the latest advances in smart wireless sensing based on an extensive review of state-of-the-art research, it promotes the further development of this area and also contributes to interdisciplinary research.

In Dreadful Desires Charlie Yi Zhang examines how the Chinese state deploys affective notions of love to regulate the population and secure China's place in the global economy. Zhang shows how the state frames love as a set of desires that encompass heteronormative intimacy, familial and communal attachment, upward mobility, and private property ownership. These desires-as circulated in performance in the nationalistic ceremony, same-sex romantic fan fiction, the wildly popular reality television dating show If You Are the One, and the cult of patriarchal personality around Xi Jinping-are explicitly based in oppressive systems of gender, class, and sexuality. Zhang contends that such desires connect love to economic survival and gender normativity in ways that underwrite Chinese neoliberalism at the expense of individual flourishing. By outlining how state-framed forms of love create desires that cannot be fulfilled, Zhang places China at the forefront of using affective attachments to nation, leader, and family in the global shifts toward exploitation and authoritarianism.

This book aims to analyze two contrasting trends of integration and rivalry among great powers and regional states of Himalaya. It examines the interactions between the great powers and the small states in the Himalayan region, analyzes the multiple effects of the great power rivalry on the regional cooperation, and predicts the possible directions of the future of the geo-politics and geo-economy in the Himalayan region by incorporating the most recent developments. The main content of the book is divided into 11 parts. The Introduction briefly explains the aims and scope of this book. The following chapter focuses on the Buddhist ties between China and the Himalayan states in the past two millennia and its dual influence in the Himalayan region. The rest 9 chapters provide an in-depth analyses of the security dilemma between China and India, Indian perspectives on China-South Asian relations, Chinese perspectives on U.S. and Japan's engagement with South Asia and Indo-Myanmar relations, and Pakistan, Sri Lanka, Bangladesh and Nepal's responses to the regional integration and great power rivalry in the Himalayan region respectively. This is the first study which brings the Himalaya region at the center of geopolitical and geo-economics cooperation and rivalry thus highlighting its significance in Asian politics. It offers a comprehensive analysis of the complicated geo-political and geo-economic competition in the Himalayan region by inviting experts from both South Asia and China to contribute chapters. It also balances the west-centered views on the great power rivalry by introducing cultural perspective and small state perspective. The broad approach adopted in the book with focus on all important countries expands the scope of readership beyond specific academic community. The book will interest academics, policy makers, journalists, general reader and students of Asian politics.

Transglutaminase: Fundamentals and Applications, a new volume in the Foundations and Frontiers in Enzymology series, stands as a comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field from the Editors, international experts discuss basic biology and structure – function relationships of transglutaminases, ongoing fundamental research, as well as new application areas, including food processing, material synthesis, biomedicine and disease treatment, and biotechnology. Approaches for sourcing transglutaminases from animals, plants, and microorganisms are considered in-depth, followed by chapters on applied uses in biomedicine, skin and bone biology and medicine, drug development, tissue engineering, seafood bioprocessing, dairy bioprocessing, synthesis of materials and polymers, and as an immobilization agent. Research protocols are also provided, including research rationale, design, substrates, assays and microassay steps for studying transglutaminases.

This book presents state-of-the-art solution methods and applications of stochastic optimal control. It is a collection of extended papers discussed at the traditional Liverpool workshop on controlled stochastic processes with participants from both the east and the west. New problems are formulated, and progresses of ongoing research are reported. Topics covered in this book include theoretical results and numerical methods for Markov and semi-Markov decision processes, optimal stopping of Markov processes, stochastic games, problems with partial information, optimal filtering, robust control, Q-learning, and self-organizing algorithms. Real-life case studies and applications, e.g., queueing systems, forest management, control of water resources, marketing science, and healthcare, are presented. Scientific researchers and postgraduate students interested in stochastic optimal control,- as well as practitioners will find this book appealing and a valuable reference.

This book presents advances in state-of-the-art solution methods and their applications to real life practical problems in optimization, control and operations research. Contributions from world-class experts in the field are collated here in two parts, dealing first with optimization and control theory and then with techniques and applications. Topics covered in the first part include control theory on infinite dimensional Banach spaces, history-dependent inclusion and linear programming complexity theory. Chapters also explore the use of approximations of Hamilton-Jacobi-Bellman inequality for solving periodic optimization problems and look at multi-objective semi-infinite optimization problems and production planning problems. In the second part, the authors address techniques and applications of optimization and control in a variety of disciplines, such as chaos synchronization, facial expression recognition and dynamic input-output economic models. Other applications considered here include image retrieval, natural earth satellites orbital transfers, snap-back repellers and modern logistic systems. Readers will learn of advances in optimization, control and operations research, as well as potential new avenues of research and development. The book will appeal to scientific researchers, mathematicians and all specialists interested in the latest advances in optimization and control.

In China, talent development has been one of the key areas of attention in national focus for the development of science and technology, education, and other areas over the past three decades, and it is especially emphasized in the national outline for medium- and long-term educational reform and development. Beijing is the leading city in educational reform, especially in the area of gifted education in mainland China. Over the past 35 years, through constant exploration and research, a comprehensive gifted education system called the Beijing Model of Gifted Education and Talent Development (BMGETD) has gradually been developed. This book presents a summary of the educational practices used in, and the research done on the BMGETD over these decades. This includes several patterns for gifted education, such as acceleration in special classes, special classes without acceleration, enrichment within regular classes, and a joint program among high schools, universities, and professional academic institutions.

This collection provides a comprehensive review of key advances in greenhouse and other forms of protected and controlled environment cultivation. Chapters discuss developments in types of production systems: greenhouses, net houses, aquaponic and vertical farming systems. A particular focus is on ways of controlling the aerial environment, including lighting and atmosphere control, and on optimising root development, including growing media, irrigation and nutrient management. Chapters also summarise advances in systems monitoring and management, including the use of sensors, decision support systems and robotics to optimise efficiency.

In Dreadful Desires Charlie Yi Zhang examines how the Chinese state deploys affective notions of love to regulate the population and secure China's place in the global economy. Zhang shows how the state frames love as a set of desires that encompass heteronormative intimacy, familial and communal attachment, upward mobility, and private property ownership. These desires-as circulated in performance in the nationalistic ceremony, same-sex romantic fan fiction, the wildly popular reality television dating show If You Are the One, and the cult of patriarchal personality around Xi Jinping-are explicitly based in oppressive systems of gender, class, and sexuality. Zhang contends that such desires connect love to economic survival and gender normativity in ways that underwrite Chinese neoliberalism at the expense of individual flourishing. By outlining how state-framed forms of love create desires that cannot be fulfilled, Zhang places China at the forefront of using affective attachments to nation, leader, and family in the global shifts toward exploitation and authoritarianism.

Health is indispensable for living a life of dignity. Currently, there is an almost universal commitment to the right to health (care). However, despite the growing legal recognition of this right, empirical evidence suggests that, as a whole, the implementation of the right to health (care) remains largely rhetorical at the domestic level. For example, although China ratified the International Covenant on Economic, Social and Cultural Rights in 2001, relatively little attention has been paid to the domestic implementation of the right to health (care). Violations of this right were also identified in reality. Given that China's health care reform is entering the so-called 'deep-water' zone, it is essential for the Chinese government to investigate how to guarantee everyone equal access to health care.Advancing the Right to Health Care in China analyses the role of accountability, a Western concept that has recently been introduced to China, in advancing the right to health care in light of China's unique political, legal and social background. In doing so, this book synthesises two different concepts: (1) the right to health; and (2) accountability, and integrates them into an analytical framework for 'right to health-based accountability'. It further provides a greater understanding of accountability and the various forms of accountability mechanisms that should be established by States. More specifically, it establishes a constructive accountability model that can be applied to specific health concerns in China, as well as in other countries, particularly those with non-electoral regimes.This book first systematically evaluates the status quo of the legislative and policy measures China has taken to give effect to the right to health care within its jurisdiction. It then identifies the shortcomings in Chinas domestic implementation of this right and seeks to address the remaining challenges through the lens of accountability. This book concludes with a set of recommendations for Chinese law- and policy-makers for implementing China's obligations under the right to health care through its draft Basic Health Law.

This book aims to portray ancient civilizations and the development of early states in China and the rest of the world during the Liangzhu period. From a global perspective, it describes the ancient Egyptian, Sumerian and Harappan civilizations, as well as lesser-known civilizations such as the Cyclades and Caral, underscoring the similarities and differences between their central settlements, capitals and material cultural remains. As for the national aspect, the book mainly explores the development process of east Asian civilization as represented by Chinese civilization and probes into the evolution of the Liangzhu, Dawenkou and Qujialing civilizations four to five thousand years ago in a search for the origins of Chinese civilization.

Perception of human beings has evolved from natural biosensor to powerful sensors and sensor networks. In sensor networks, trillions of devices are interconnected and sense a broad spectrum of contexts for human beings, laying the foundation of Internet of Things (IoT). However, sensor technologies have several limitations relating to deployment cost and usability, which render them unacceptable for practical use. Consequently, the pursuit of convenience in human perception necessitates a wireless, sensorless and contactless sensing paradigm. Recent decades have witnessed rapid developments in wireless sensing technologies, in which sensors detect wireless signals (such as acoustic, light, and radio frequency) originally designed for data transmission or lighting. By analyzing the signal measurements on the receiver end, channel characteristics can be obtained to convey the sensing results. Currently, significant effort is being devoted to employing the ambient Wi-Fi, RFID, Bluetooth, ZigBee, and television signals for smart wireless sensing, eliminating the need for dedicated sensors and promoting the prospect of the Artificial Intelligence of Things (AIoT). This book provides a comprehensive and in-depth discussion of wireless sensing technologies. Specifically, with a particular focus on Wi-Fi-based sensing for understanding human behavior, it adopts a top-down approach to introduce three key topics: human detection, localization, and activity recognition. Presenting the latest advances in smart wireless sensing based on an extensive review of state-of-the-art research, it promotes the further development of this area and also contributes to interdisciplinary research.

This book aims to analyze two contrasting trends of integration and rivalry among great powers and regional states of Himalaya. It examines the interactions between the great powers and the small states in the Himalayan region, analyzes the multiple effects of the great power rivalry on the regional cooperation, and predicts the possible directions of the future of the geo-politics and geo-economy in the Himalayan region by incorporating the most recent developments. The main content of the book is divided into 11 parts. The Introduction briefly explains the aims and scope of this book. The following chapter focuses on the Buddhist ties between China and the Himalayan states in the past two millennia and its dual influence in the Himalayan region. The rest 9 chapters provide an in-depth analyses of the security dilemma between China and India, Indian perspectives on China-South Asian relations, Chinese perspectives on U.S. and Japan's engagement with South Asia and Indo-Myanmar relations, and Pakistan, Sri Lanka, Bangladesh and Nepal's responses to the regional integration and great power rivalry in the Himalayan region respectively. This is the first study which brings the Himalaya region at the center of geopolitical and geo-economics cooperation and rivalry thus highlighting its significance in Asian politics. It offers a comprehensive analysis of the complicated geo-political and geo-economic competition in the Himalayan region by inviting experts from both South Asia and China to contribute chapters. It also balances the west-centered views on the great power rivalry by introducing cultural perspective and small state perspective. The broad approach adopted in the book with focus on all important countries expands the scope of readership beyond specific academic community. The book will interest academics, policy makers, journalists, general reader and students of Asian politics.

This book offers a systematic and rigorous treatment of continuous-time Markov decision processes, covering both theory and possible applications to queueing systems, epidemiology, finance, and other fields. Unlike most books on the subject, much attention is paid to problems with functional constraints and the realizability of strategies. Three major methods of investigations are presented, based on dynamic programming, linear programming, and reduction to discrete-time problems. Although the main focus is on models with total (discounted or undiscounted) cost criteria, models with average cost criteria and with impulsive controls are also discussed in depth. The book is self-contained. A separate chapter is devoted to Markov pure jump processes and the appendices collect the requisite background on real analysis and applied probability. All the statements in the main text are proved in detail. Researchers and graduate students in applied probability, operational research, statistics and engineering will find this monograph interesting, useful and valuable.

Multiscale Modeling of Additively Manufactured Metals: Application to Laser Powder Bed Fusion Process provides comprehensive coverage on the latest methodology in additive manufacturing (AM) modeling and simulation. Although there are extensive advances within the AM field, challenges to predictive theoretical and computational approaches still hinder the widespread adoption of AM. The book reviews metal additive materials and processes and discusses multiscale/multiphysics modeling strategies. In addition, coverage of modeling and simulation of AM process in order to understand the process-structure-property relationship is reviewed, along with the modeling of morphology evolution, phase transformation, and defect formation in AM parts. Residual stress, distortion, plasticity/damage in AM parts are also considered, with scales associated with the spatial, temporal and/or material domains reviewed. This book is useful for graduate students, engineers and professionals working on AM materials, equipment, process, development and modeling.