This book presents a comprehensive study on intelligent container terminals. Based on the development experience gained to date with container terminals, it analyzes information flows and their interactions with container terminals; illustrates the operation management process from information collection to resource planning and from equipment scheduling to field operation; highlights several dynamic decision-making problems concerning digital operation processes and container terminals; reveals the basis of the discrete logistics system; and discusses the future of intelligent container terminals.

Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. "Recent Advances in Cancer Research and Therapy" reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment.
Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies.Formatted for a broad audience including all working in researching cancer treatments and therapies.Discusses special traits and results of Chinese cancer research.

Native Fibrin Gel Networks and Factors Influencing their Formation in Health and Disease.- The Structure and Evolution of Vertebrate Fibrinogen: A Comparison of the Lamprey and Mammalian Proteins.- Nucleotide Sequences of the Three Genes Coding for Human Fibrinogen.- On the Identity of Fibrin(ogen) Oligomers Appearing During Fibrin Polymerization.- Immunochemical Studies of A? Chain Crosslinking.- Abnormal Fibrinogens with Two Structural Defects.- Electrophoretic Characterizations of Cross-Linked Fibrinogen Derivatives in Blood and Vascular Tissue by Zonal Immobilization on Glyoxyl Agarose.- Studies on the Localization and Accessibility of Sites in Fibrin which Are Involved in the Acceleration of the Activation of Plasminogen by Tissue-Type Plasminogen Activator.- Prothrombinase: Recognition and Developments.- The Initiation of the Tissue Factor Dependent Pathway of Blood Coagulation.- Interactions Between the Contact System, Neutrophils and Fibrinogen.- A New Trisaccharide Sugar Chain Linked to a Serine Residue in the First EGF-Like Domain of Clotting Factors VII and IX and Protein Z.- Multiple Epitope Specificity of Monoclonal Antibodies to a Single Synthetic Peptide: Use in the Characterization of the GP lIb-IIIa Binding Domain of von Willebrand Factor.- Factor VII and Dietary Fat Intake.- Characterization of Snake Venom Principles Affecting Blood Coagulation and Platelet Aggregation.- Thrombin-Like Venom Enzymes: Structure and Function.- Thrombin Inhibition by Synthetic Hirudin Peptides.- Effects of Structural Modifications on the Properties of Tissue Plasminogen Activator (tPA).- Molecular Genetics of Alpha 2 Plasmin Inhibitor.- Biological Properties of Hybrid Plasminogen Activators.- The Regulation of the Activaton of the Fibrinolysis System.- The Mechanisms of the Activation of Plasminogen by Streptokinase and Urokinase.- Protein C and Fibrinolysis: A Link Between Coagulation and Fibrinolysis.- Transformation of Prostacyclin (PGI2) to a Biologically Active Metabolite: 5(6)-Oxido-PGI1 by Cytochrome P450-Dependent Epoxygenase.- Studies on the Localization of Fibrinogen Binding Sites on Platelet Glycoprotein IIIa.- Affinity Labeling of Nucleotide Binding Sites of Enzymes and Platelets.- The Effect of Ganodermic Acid S on Human Platelets.- Role of Insulin Receptors in the Expression of Prostaglandin E1 Binding Activity in Platelets.- Platelet-Fibrin Interaction in the Suspension and Under Flow Conditions.- An Independent Haemostatic Mechanism: Shear Induced Platelet Aggregation.- Regulation of Eicosanoid Biosynthesis in Endothelial Cells: Critical Role of De Novo Synthesis of Prostaglandin Endoperoxide Synthase.- Modulation of Endothelial Function by Hypoxia: Perturbation of Barrier and Anticoagulant Function, and Induction of a Novel Factor X Activator.- Fibrin and the Vessel Wall.- Interactions between Fibrin, Collagen and Endothelial Cells in Angiogenesis.- New Developments in Thrombolytic Therapy.- Coronary Thrombosis: Pathogenesis and Prevention.- Implications of the TIMI Trials.- Thrombotic Microangiopathy.- Clinical Trials with Alteplase (RT-pa) in Acute Myocardial Infarction.- The Effects of Streptokinase and Tissue Plasminogen Activator on Left Ventricular Function.- Modern Strategies for Treatment of Acute Myocardial Infarction: Significance of Haemostaseological and Rheological Findings.- Clinical Application of Tissue Plasminogen Activator Therapy in Acute Myocardial Infarction.- Fibrinogen Proteolysis and Coagulation System Activation During Thrombolytic Therapy.- Altered Rheological Properties of Blood Following Administrations of Tissue Plasminogen Activator and Streptokinase in Patients with Acute Myocardial Infarction.- Monoclonal Antibodies for the Detection of Thrombosis.- The Pharmacology and Clinical Pharmacology of Defibrotide: A New Profibrinolytic, Antithrombotic, and Anti-Platelet Substance.- Author Index.

This book demonstrates the concept of ecological system of the smart ports. The innovation is emphasized as the essence of the ecological system as well as the prerequisite and foundation of sustainable development of smart ports. The main supporting technologies of smart ports, including cyber-physical system, middle-office system, blockchain, artificial intelligence, machine vision, AR/VR, system simulation and emulation, digital monitoring and diagnosis, etc., are introduced with concepts and development descriptions as well as practical application cases. It could be used as demonstration and reference for the administrative staff, engineers and technicians as well as researchers in construction and operation of smart ports.

This volume is divided into three sections, synaptic transmission, synaptic modulation, and synaptic plasticity, and deals with disorders brought on by alcohol. Some of the topics covered include: molecular targets underlying ethanol-mediated reduction of hormone release from neurohypophysial nerve terminals; alcohol and general anesthetic modulation of GABAA and neuronal nicotinic acetylcholine receptors; alcohol and the 5-HT3 receptor, adenosine and ethanol; metabotropic hypothesis for ethanol sensitivity of GABAergic and glutamatergic central synapses; alcohol, memory, and molecules; novel forms and analyses of ethanol effects on synaptic plasticity; and ethanol suppression of hippocampal plasticity.

This book introduces readers to oracle bone inscriptions (OBI), the oldest known form of Chinese writing. It presents 120 rubbings made from unearthed animal bones and turtle shells that the Shang royal court employed to record royal divinations 3500 years ago, covering topics ranging from ancestor worship, rituals, and astronomy to agriculture, war, and hunting. Each rubbing is accompanied by a graph-to-graph transcription, a translation and a detailed annotation. The book is intended for both general readers and scholars who are interested in ancient civilizations and Early China in particular, acquainting them not only with OBI graphs and the development of the Chinese writing system, but also the history of the Shang Dynasty. The didactic and tutorial format makes this book ideal for teaching and for self-learning. Sumerian, Egyptian, Chinese OBI and Mayan constitute the four pristine writing systems. Of these, only Chinese writing has remained logographic and survived to the present day. The study of OBI not only plays a pivotal role in connecting archaeology to history, but is also of great importance to the comparative study of the origin of writing and civilization. Though there are numerous books on Mayan and Egyptian hieroglyphs, there are very few on OBI; this book fills that gap.

This book presents a comprehensive study on intelligent container terminals. Based on the development experience gained to date with container terminals, it analyzes information flows and their interactions with container terminals; illustrates the operation management process from information collection to resource planning and from equipment scheduling to field operation; highlights several dynamic decision-making problems concerning digital operation processes and container terminals; reveals the basis of the discrete logistics system; and discusses the future of intelligent container terminals.

The International Scientific Symposium on Fibrinogen, Thrombosis, Coagulation, and Fibrinolysis was held in Academia Sinica, Taipei, Taiwan, Republic of China, on August 30 - September 1, 1989. This Symposium has provided a forum for the free exchange of information in this important and rapidly advancing research field. This proceedings volume provides a published record of 46 papers presented at the Symposium. The sponsors have exerted no influence on the scientific opinions or positions of the participants in the Symposium. It is hoped that this Symposium will stimulate further worldwide cooperation and collaboration in these vital fields for the benefit of all human kind. This volume is composed of four parts. The first part consists of 8 papers on Fibrinogen and Fibrin: Biochemistry, Molecular Biology, and Physiology. The second part contains 16 papers on Coagulation and Fibrinolysis: Biochemistry, Molecular Biology, and Physiology. The third part has 10 papers on Cardiovascular Cell Biology: Biochemistry, Molecular Biology, and Physiology. The fourth part comprises 12 papers on Clinical Studies of the Cardiovascular System: Thrombotic and Bleeding Disorders and Thrombolytic Therapy. The Author Index with addresses of all contributors and the Subject Index of all 46 papers are arranged at the end of this volume.

This book demonstrates the concept of ecological system of the smart ports. The innovation is emphasized as the essence of the ecological system as well as the prerequisite and foundation of sustainable development of smart ports. The main supporting technologies of smart ports, including cyber-physical system, middle-office system, blockchain, artificial intelligence, machine vision, AR/VR, system simulation and emulation, digital monitoring and diagnosis, etc., are introduced with concepts and development descriptions as well as practical application cases. It could be used as demonstration and reference for the administrative staff, engineers and technicians as well as researchers in construction and operation of smart ports.

This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials. The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.