Nick Charles MBE is a pioneer in treating alcohol dependency. As the founder of both the Chaucer Clinic and the Gainsborough Foundation, he was the first person to be honoured by the Queen 'for services to people with alcohol problems' and his work - over four decades - has helped tens of thousands of people. But Nick's decorated success overlays an extraordinary and unforgettable personal journey, for Nick was once an alcoholic vagrant sleeping rough on the streets of London. In 50 Years of Hard Road, Nick details his time in the abyss of alcohol addiction; a period that despatched relationships, his health, his career, and so much more. Forced to live on the streets for four years, Nick recalls the tough times, the characters he met, and the ever-present call of alcohol, but also how he slowly built up two carrier bags-worth of painstaking research into alcohol and its effects on his fellow man. It was through the documents in these carrier bags that Nick's life was to change forever when, in the mid-1970s, he was taken under the wing of a doctor who cared for those on skid row. This dedicated medic recognised the treasure trove of information Nick had developed. 50 Years of Hard Road is a remarkable, uplifting, and often humorous story of one man's journey from the depths of life-crushing alcohol dependency, to running alcohol clinics and programmes across the country. It describes an incredible life filled with high points, low points, and amazing adventures in-between.

From the President of the Research Society on Alcoholism The sixteenth volume of Recent Developments in Alcoholism contains the latest information on the field of alcoholism treatment research. This scholarly volume includes comprehensive reviews of the methodologies available to evaluate treatment outcome, state-of-the art psychosocial interventions, and recent advances in pharmacological adjuncts to treatment that are currently available and those on the brink of application. Other sections of the book address special issues in the treatment of alcohol dependence, including the treatment of the adolescents and other unique populations, the management of tobacco dependence, and the role of spirituality in recovery, among others. The clinician will find these reviews an important resource for learning about e- dence based treatments for alcoholism, and the researcher will find the synt- sis of recent developments informative and forward looking. The research agenda for the future rests soundly on the progress to date and additional advances in the treatment of alcoholism can be predicted in the near future. Stephanie O'Malley, Ph. D. President, Research Society on Alcoholism xi Preface From the President of the American Society of Addiction Medicine This excellent volume presents investigations covering a wide spectrum of scientific issues. It is also evident that many of these articles have clinical s- nificance, ranging from assessments of disorder, monitoring clinical progress, and behavioral and pharmacological interventions.

It was during the course of the eighteenth and nineteenth centuries that the problem of chronic alcohol dependence in modern society and its consequent medical effects emerged. The topic of drunkenness figures prominently in the thinking and writing of social reformers, politicians, theorists, medical practitioners, and psychiatrists. Eventually, by the mid-nineteenth century, 'alcoholism' was named as the disease of habitual drunkenness. Possibly the most important book to predict this was Trotter's Essay, written in 1804. Through case studies based on wide experience, he detailed the manifestations of alcoholism, ventured therapeutic recommendations, and squarely termed drunkenness a disease - indeed, a mental disease. Originally published in 1988 as part of the Tavistock Classics in the History of Psychiatry series, Roy Porter's Introduction to this facsimile reprint locates Trotter's work within the wider history of the evolution of the idea of alcoholism. It also examines the Essay in the context of Trotter's own life and mind - a mind preoccupied with what he saw as the degenerative tendencies of modern civilization and with the wider issues of drug dependence.

The misuse of both legally prescribed and illegally supplied drugs is now so widespread that it affects, either directly or indirectly, a high proportion of the population, impacting many areas of daily life. There are few countries that are not touched by some aspect of substance misuse and the consequences for individuals, families and the wider community can be devastating.

The third edition of Symptoms and Signs of Substance Misuse has been completely updated and revised, continuing to provide trusted information from leading experts.

• Basic principles of treatment for the most commonly encountered substances from tobacco and alcohol to cocaine and heroin, as well as 'designer' drugs
• The legal aspects of substance misuse highlighted throughout
• Convenient A-Z format helps you find information at a glance
• References and further reading direct you to more authoritative information about each substance

With specialist information clearly explained along with a full glossary, this handy pocket-sized book is essential for all health professionals needing a concise and up-to-date overview of the signs and symptoms of substance misuse as well as the management and treatment options available. Junior hospital doctors, emergency department staff, primary care teams, community workers and counsellors will find this text invaluable. The book is also an excellent resource for police officers as well as a quick reference guide for professionals involved in setting up and managing drug and alcohol policies in organisations and businesses."

Alcoholism: A Review of Its Characteristics, Etiology, Treatment, and Controversies provides an accurate picture of the current state of research and treatment effectiveness in the field of alcoholism. Using compelling evidence, Irving Maltzman describes how the field has been distorted by the behavior therapy approach. A distinguished experimental psychologist at the University of California, Los Angeles, Professor Maltzman has written a comprehensive, important work marked by incisive argument. Alcoholism is an excellent reference for academics as well as professionals working in addictions treatment.

This newly updated and streamlined edition of Group Psychotherapy with Addicted Populations provides proven strategies for combating alcohol and drug addiction through group psychotherapy. The interventions discussed in the book build on a foundation of addiction as an attachment disorder rooted in the understanding of addiction as a family disease. An appreciation of group and organizational dynamics is used to address the complex experience of developmental trauma that underlies addiction. Having identified the essential theoretical underpinnings of supporting recovery from addiction, the second half of the book gives a thorough nuts and bolts description of constructing a psychotherapy group and engaging productively in the successive phases of its development from initiation of treatment to termination. The book concludes with specific recommendations for group psychotherapists to increase their competence with groups, deepen their appreciation of group and organizational dynamics and develop a community of support for their own well-being. These methods are important for psychotherapists working with addicted populations who are inexperienced with group psychotherapy as well as seasoned group psychotherapists wishing to enhance their work.

Nick Charles MBE is a pioneer in treating alcohol dependency. As the founder of both the Chaucer Clinic and the Gainsborough Foundation, he was the first person to be honoured by the Queen 'for services to people with alcohol problems' and his work - over four decades - has helped tens of thousands of people. But Nick's decorated success overlays an extraordinary and unforgettable personal journey, for Nick was once an alcoholic vagrant sleeping rough on the streets of London. In 50 Years of Hard Road, Nick details his time in the abyss of alcohol addiction; a period that despatched relationships, his health, his career, and so much more. Forced to live on the streets for four years, Nick recalls the tough times, the characters he met, and the ever-present call of alcohol, but also how he slowly built up two carrier bags-worth of painstaking research into alcohol and its effects on his fellow man. It was through the documents in these carrier bags that Nick's life was to change forever when, in the mid-1970s, he was taken under the wing of a doctor who cared for those on skid row. This dedicated medic recognised the treasure trove of information Nick had developed. 50 Years of Hard Road is a remarkable, uplifting, and often humorous story of one man's journey from the depths of life-crushing alcohol dependency, to running alcohol clinics and programmes across the country. It describes an incredible life filled with high points, low points, and amazing adventures in-between.

Since the legalisation of off-course cash betting in 1960, and the rise of varying forms of gambling, the British have come to be known as a nation of gamblers. Until this study was published in 1976, barely any evidence existed against which to assess the claim that gambling had become a major social problem. The authors present data drawn from area surveys carried out in Swansea, Sheffield, Wanstead and Woodford, and explore how well previous sociological theories of gambling agree with their findings, particular in connection with certain aspects of work and leisure. Examining different forms of gambling, including betting, bingo and gaming machines, the chapters consider how gambling choices vary between different social groups, and how much time and money is spent on them. With the internet making it easier than ever before to place bets, this title is especially relevant, and provides a systematic basis for an explanation of gambling in relation to social structure.

Author Mark S. Gold presents the latest medical information on nicotine and tobacco's neurobiological, physiological, and psychological effects. This timely monograph also discusses the latest diagnostic and treatment programs as well as model programs for use by practitioners which were developed by the National Cancer Institute and other eminent organizations. The author also includes a comprehensive history of tobacco use.

It was during the course of the eighteenth and nineteenth centuries that the problem of chronic alcohol dependence in modern society and its consequent medical effects emerged. The topic of drunkenness figures prominently in the thinking and writing of social reformers, politicians, theorists, medical practitioners, and psychiatrists. Eventually, by the mid-nineteenth century, 'alcoholism' was named as the disease of habitual drunkenness. Possibly the most important book to predict this was Trotter's Essay, written in 1804. Through case studies based on wide experience, he detailed the manifestations of alcoholism, ventured therapeutic recommendations, and squarely termed drunkenness a disease - indeed, a mental disease. Originally published in 1988 as part of the Tavistock Classics in the History of Psychiatry series, Roy Porter's Introduction to this facsimile reprint locates Trotter's work within the wider history of the evolution of the idea of alcoholism. It also examines the Essay in the context of Trotter's own life and mind - a mind preoccupied with what he saw as the degenerative tendencies of modern civilization and with the wider issues of drug dependence.

Drug Abuse Treatment, together with its companion volume, Alcohol Abuse Treatment, critically examines the many difficult issues and complex strategies associated with the successful treatment of substance abuse today. Because of the high cost in lives, health, and dollars, the need for improved tech-niques and strategies for the treatment and reduction of substance abuse has become a critical national priority. In this volume of Drug & Alcohol Abuse Reviews, Ronald R. Watson and key researchers in the field of drug abuse treatment evaluate both old and new methods, carefully reviewing current data to determine the value of the most important treatment programs in current use. Featured topics include: cocaine and heroin addiction treatment relapse problems and treatment nicotine abuse treatment strategy for drug treatment systems psychological correlates of drug abuse outpatient drug abuse treatment pharmacotherapy for drug abuse Drug Abuse Treatment and its complementary volume on Alcohol Abuse Treatment together offer a thorough review and analysis of drug and alcohol abuse treatment options, providing researchers and clinicians with a valuable framework for understanding, planning, and delivering the effective substance abuse treatment that is so urgently needed now.

In the early 1980s the transtheoretical model of change was still in its infancy. Seminal publications were just appearing, but the model already seemed to hold such promise that we made it the organizing theme for the Third International Conference on Treatment of Addictive Behaviors (ICTAB-3), which convened in Scotland in 1984. That meeting gave rise to the first edition of this volume (Miller & Heather, 1986), which focused on processes involved in moving people from one stage to the next. With the volume still in print more than a decade later, we were approached by Plenum Press with the idea of preparing this second edition. We were, obvi ously, persuaded that there was merit to the idea. Since 1986 the work of Pro chaska and DiClemente has grown exponentially in popularity and influence. In Britain and the Americas, it is now unusual to find an addiction professional who has not at least heard about the stages of change, and more sophisticated applica tions of the transtheoretical model are spreading through health care systems and well beyond. The model has influenced professional training, health care delivery, and the design of many studies including a number of large clinical trials."

Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders. These advances have a far reaching impact on many areas of neuroscience, including alcohol research. Studies using human alcoholic brains, gene knockout mice, and gene expression profiling have established a clear link between alcoholism and an altered neuroimmune profile. This book integrates emerging knowledge on neural-immune interactions with key discoveries in alcohol research and provides a comprehensive overview of neural-immune interactions in brain function and behavior associated with alcohol use disorders. While "Neural Immune Interaction in Brain Function and Alcohol Related Disorders" focuses on neural-immune interactions in areas directly related to alcohol use disorders, it is not intended to be all inclusive. Several areas, including sleep disorders, pain, and cholinergic anti-inflammatory pathways, are not covered as independent chapters but briefly mentioned in the text. The close relevance of these topics to neural-immune interactions and alcohol use disorders warrants future discussion and more research efforts."

This book deals with recent perspectives on the panel of addiction behavior in a vast amount of population (young and adult). Thanks to the contribution of experts of the topic of addiction the volume will furnish new perspectives to formulate assessment, diagnosis and intervention in response to the increasing variety of addictions. It focuses the assessment of executive functions in substance and behavioral addictions. More specifically, this assessment consists of a new approach not only inherent to the diagnosis, but also to the treatment and prevention of addictions. In fact, there is a strict relationship between executive functions (EF) and addictive behavior: EF plays a remarkable role in significant phenomena for the treatment of addictions, such as craving, relapse and compliance to treatment.

Can certain foods hijack the brain in ways similar to drugs and alcohol, and is this effect sufficiently strong to contribute to major diseases such as obesity, diabetes, and heart disease, and hence constitute a public health menace? Terms like "chocoholic" and "food addict" are part of popular lore, some popular diet books discuss the concept of addiction, and there are food addiction programs with names like Food Addicts in Recovery Anonymous. Clinicians who work with patients often hear the language of addiction when individuals speak of irresistible cravings, withdrawal symptoms when starting a diet, and increasing intake of palatable foods over time. But what does science show, and how strong is the evidence that food and addiction is a real and important phenomenon?
Food and Addiction: A Comprehensive Handbook brings scientific order to the issue of food and addiction, spanning multiple disciplines to create the foundation for what is a rapidly advancing field and to highlight needed advances in science and public policy. The book assembles leading scientists and policy makers from fields such as nutrition, addiction, psychology, epidemiology, and public health to explore and analyze the scientific evidence for the addictive properties of food. It provides complete and comprehensive coverage of all subjects pertinent to food and addiction, from basic background information on topics such as food intake, metabolism, and environmental risk factors for obesity, to diagnostic criteria for food addiction, the evolutionary and developmental bases of eating addictions, and behavioral and pharmacologic interventions, to the clinical, public health, and legal and policy implications of recognizing the validity of food addiction. Each chapter reviews the available science and notes needed scientific advances in the field.

Mark Schuckita (TM)s Drug and Alcohol Abuse has been a clinical mainstay for over a quarter century. Now the authora (TM)s trusted expertise is available in a new Sixth Edition, thoroughly revised for content, updated references, and streamlined for increased usefulness.

Schuckit combines his experience as practitioner, researcher, and teacher to give professionals and students across the health and mental health disciplines a working knowledge of drug-related pathology, beginning with pharmacology, drug mechanisms, and genetic factors. And the Sixth Edition is as accessible as its predecessors, striking the right comfort level for the classroom or the emergency room.

-Clinical/emergency orientation suited to both chronic misuse and acute situations

-Coverage reflects current trends in alcohol, drug, and multidrug use, abuse, and dependence

-Concise chapters for quick reference

-Updated bibliographya "approximately 80% of citations are post-2000

-Diagnostic information reflects upcoming changes to the DSM

-Latest strategies in treatment (psychological and pharmacological) and rehabilitation

All material is organized for ease of use, whether the reader needs fast answers in a crisis, seeks new ideas for helping long-term patients or clients, or is just becoming familiar with the different drug classifications. This new edition offers expanded knowledge of a wide-ranging problem and a growing and clinically important population, and authoritative suggestions for effective care.

Volume eight brings up to date several areas important to physicians who care for people with addictive disorders. It deals with the topic of combined alcohol and other drug dependences, and includes chapters on definition of the dependence syndrome, social deviancy and alcohol dependence, and biolo

The last few years have seen an increasing awareness among the mental health community to the unique situations of the person suffering simultaneously from mental health disorders and substance abuse addiction. Complementing this rise in attention has been a realization of the unique challenges faced by mental health professionals engaged in the treatment of these clients, and a startling acknowledgement of the gap in the existing literature on the topic. There is currently no available treatment manual that includes specific training on how to treat this difficult population, following guidelines and practical instructions based on treatment practices already employed by the authors. This treatment manual will fill an important gap in the literature by addressing the specific challenges faced by the clinician treating individuals with co-occurring schizophrenia and substance abuse disorders.
The unique strength of the proposed volume is its close adherence to a treatment plan proven successful by empirical research and now being made available for the practicing clinician. The book is designed as a manual for mental health professionals, and follows a program which incorporates various treatment components, from motivational interviewing, urinalysis contingency, and social skills training to education and coping skills, problem solving and relapse prevention, and finally termination. Guidelines are clearly established for these treatment modes, utilizing case examples and fictional situations to allow the reader to profit more directly from the lessons in the text. The book follows a treatment outline that will allow the clinician to pattern a series of therapy sessions after thesuggested timeframe found within the text. Additionally, the format and flow of individual sessions is carefully considered and discussed, allowing the clinician a model from which to base a treatment plan.

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.

The formation of drug policy is a complex phenomena influenced by a multi tude of sources. Among others, these influences include historical factors, contemporary public opinion regarding the nature and magnitude of drug use and abuse, the portrayal of illicit drugs and drug use in the media, and lobbying efforts by special interest groups (e. g. , The Drug Policy Foundation), including government agencies (e. g. , the Justice Department and law enforcement). An additional source of influence are the activities of specialists directly engaged in studying drug use and treating drug dependence. This includes individuals involved in drug treatment, anthropological and cultural studies, policy analy ses, basic psychological and pharmacological research, research on the epide miology of drug use and dependence, and research on prevention. This influ ence by specialists might be usefully distinguished from those influences first mentioned for two reasons: First, studies of drug use and dependence attempt to uncover empirical generalizations about drugs, and second, because these findings are empirical, there is a hope that they guide, at least to some extent, the actions of other forces that more directly determine drug policy. Psychology as an empirical discipline has long been interested in the use of psychoactive drugs. At the level of basic science in psychopharmacology, a most important contribution has been the demonstration that drugs of abuse function as reinforcers and thus enter into the same psychological processes as do other appetitive stimuli.

From the President of the American Society of Addiction Medicine Recent Developments in Alcoholism (Volume 10) is a major contribution to the literature of addiction medicine. This volume, 'ru.cohol and Cocaine: Similarities and Differences," contains an impressive collection of chapters from the basic research, epidemiological, and clinical research perspectives, as well as articles that address the relative policy issues and clinical application and patient care concerns. It also sends a message to those who would still distinguish between alcohol and drugs, or legal and illegal drugs. In the research laboratory, in the intentions and behavior of the user, and by the clinician, such distinctions have never been upheld. The first section, "Clinical Pathology," includes chapters on the role of alcohol in cocaine dependence, dual-diagnosis empirical and developmental humanistic approaches, and on neuroendocrine and catecholamine levels in humans during administration and withdrawal of cocaine and alcohol, emer gency room evaluation of cocaine-associated neuropsychiatric disorders, and clinical and pharmacological interactions of alcohol and cocaine. These chap ters, written by authors who are preeminent in their fields, offer a broad perspective to both the researcher and the clinician on relevant issues in clinical pathology. ."

Your blueprint to develop and manage effective co-occurring treatment programs! Sequential or parallel treatments for co-occurring disorders are much less effective than a quality co-occurring treatment program. Most mental health and substance abuse professionals know how to provide an effective program for individuals with a substance use or mental health disorder, but few are aware of the issues involved in providing services for those with dual diagnosis. Designing, Implementing, and Managing Treatment Services for Individuals with Co-Occurring Mental Health and Substance Use Disorders: Blueprints for Action gives you with the tools you need to develop an effective program specific to co-occurring treatment as well as to implement and manage the program's services. Author Edward Hendrickson shares his knowledge from over two decades of developing and implementing co-occurring treatment services. Designing, Implementing, and Managing Treatment Services for Individuals with Co-Occurring Mental Health and Substance Use Disorders: Blueprints for Action is thorough, insightful, and informative, covering all facets of plan and execution, helping you form strategies to address a co-occurring treatment program's unique issues. The book examines the historical basis of the current dual treatment system to provide the philosophical tenets the program must follow and the essential qualities for an effective treatment program. It explores the issues in creating a new program or expanding an existing one, as well as the mechanics of day-to-day management. Helpful appendices, tables, and case examples illustrate the discussion. Designing, Implementing, and Managing Treatment Services for Individuals with Co-Occurring Mental Health and Substance Use Disorders: Blueprints for Action discusses: developing the necessary infrastructure for integrated treatment programs the eight essential qualities for an effective treatment program choosing a target population identifying specific services to implement implementation of services in an existing treatment setting implementation of services in a non-mental health or substance abuse setting hiring and training staff clinical supervision and human resource development program management issues multilevel and multi-organization systems steps to ensure program survival Designing, Implementing, and Managing Treatment Services for Individuals with Co-Occurring Mental Health and Substance Use Disorders: Blueprints for Action is more than an instructional text for students; it is an essential resource for any substance abuse and mental health professional considering implementing a co-occurring treatment program.