In this book, the author argues that no current philosophical theory of evidence in clinical medical science is adequate. None can accurately explain the way evidence is gathered and used to confirm hypotheses. To correct this, he proposes a new approach called the weight of evidence account. This innovative method supplies a satisfactory explanation and rationale for the "hierarchical pyramid" of evidence-based medicine, with randomized clinical trials and their derivatives, meta-analyses, and systematic reviews of randomized clinical trials at the top and case reports, case series, expert opinion, and the like at the bottom. The author illustrates the development of various "levels" of evidence by considering the evolution of less invasive surgical treatments for early breast cancer. He shows that the weight of evidence account explains the notion of levels of evidence and other efforts to rank them. In addition, he presents a defense of randomization as a method to maximize accuracy in the conduct of clinical trials. The title also considers ethical issues surrounding experimentation with medical therapies in human subjects. It illustrates and discusses these issues in studies of respiratory therapies in neonates and treatment for certain cancers in adults. The author shows that in many cases sufficient evidence can be accrued to warrant generally accepted new therapies without the need for evidence derived from randomized clinical trials.

Ecosystems and Nature brings together the work of leading authorities in biodiversity research. It provides readers with a broad interdisciplinary perspective on the major issues in biodiversity, including economics, natural science, management and ethics.The collection is divided into four main sections: part I introduces some fundamental scientific and socio-economic concepts and analysis in order to illustrate the complexities involved in the human-ecosystems interface; part II deals with the valuation of ecosystems with special emphasis on the main biomes, faults, wetlands, marine systems, grasslands and agriculture; part III covers the problem of value appropriation and the relevant constraints and available policy instruments; the final section focuses on the difficult ethical issues that surround utilization and conservation of biodiversity.

In Rescuing Humanity, Willem H. Vanderburg reminds us that we have relied on discipline-based approaches for human knowing, doing, and organizing for less than a century. During this brief period, these approaches have become responsible for both our spectacular successes and most of our social and environmental crises. At their roots is a cultural mutation that includes secular religious attitudes that veil the limits of these approaches, leading to their overvaluation. Because their use, especially in science and technology, is primarily built up with mathematics, living entities and systems can be dealt with only as if their "architecture" or "design" is based on the principle of non-contradiction, which is true only for non-living entities. This distortion explains our many crises. Vanderburg begins to explore the limits of discipline-based approaches, which guides the way toward developing complementary ones capable of transcending these limits. It is no different from a carpenter going beyond the limits of his hammer by reaching for other tools. As we grapple with everything from the impacts of social media, the ongoing climate crisis, and divisive political ideologies, Rescuing Humanity reveals that our civilization must learn to do the equivalent if humans and other living things are to continue making earth a home.

This Open Access book illustrates the power of stories to illuminate ethical concerns that arise in public health. It complements epidemiological or surveillance evidence, and reveals stakeholder perspectives crucial for public health practitioners to develop effective and ethical public health interventions. Because it relies on the natural and universal appeal of stories, the book also serves to introduce the field of public health to students considering a career in public health. The opening section of the book also serves as a more didactic introduction to public health ethics and the field of narrative ethics. It describes the field of public health ethics including ethical principles relevant to public health practice and research, and the advantages of a narrative ethics approach. That approach explores the problems and the ethical challenges of public health from the inside, from the perspective of those experiencing health problems to the challenges of those who must address these problems. The later sections consist of 14 chapters that present the actual stories of these public health problems and challenges. In narrative style they range from first person narratives of both practitioners and citizens, to analysis of published short stories. The problems and challenges they address include issues relating to justice concerns, surveillance and stigma, community values and the value of community, trust and the value of information, and freedom and responsibility. Specific public health topics include resource allocation, restricting liberty to protect the community from health threats, and the health impact of trauma, addiction, obesity and health disparities.

In recent years there has been increased recognition of the global burden of mental disorders, which in turn has led to the expansion of preventive initiatives at the community and population levels. The application of such public health approaches to mental health raises a number of important ethical questions. The aim of this collection is to address these newly emerging issues, with special attention to the principle of prevention and the distinctive ethical challenges in mental health. The collection brings together an interdisciplinary group of experts in bioethics, mental health, public health, and global health.

This book brings the animal into the scholarly discussion of animal-assisted therapy and other interventions. Challenging the current reliance on outcome studies, the author offers a new way of thinking empirically about animal-assisted interventions-analysis of human-animal interaction as a critical component. Through empirical demonstrations from laboratory and applied settings, the book encourages practitioners and scholars to undergo a deeper examination of the basic interactions that occur between clients or patients and therapy animals. Dr. Fournier provides new ideas on measurement, experimentation, and interpretation of human-animal interaction, aimed at identifying the role of the animal in interventions for human health and well-being.

This book provides a current analysis of the legal and ethical challenges in preparing for and responding to chemical, biological, radiological, nuclear and explosive (CBRNE) crises. From past events like the Chernobyl nuclear incident in Russia or the Bhopal chemical calamity in India, to the more recent tsunami and nuclear accident in Japan or the Ebola crisis in Africa, and with the on-going threat of bioterrorism, the need to be ready to respond to CBRNE crises is uncontroversial. What is controversial is whether we are on a path that adequately prepares us for the next event. The ethical and legal scholars in this volume hold that much work remains to be done and offer this book to stimulate further reflection and dialogue around CBRNE crises. This is an indispensable book for both students and scholars of bioethics, international law, public health, as well as for regulators and administrators developing policy and legislation related to public health planning and emergency responses.

Recent advances in the brain sciences have dramatically improved our understanding of brain function. As we find out more and more about what makes us tick, we must stop and consider the ethical implications of this new found knowledge. Will having a new biology of the brain through imaging make us less responsible for our behavior and lose our free will? Should certain brain scan studies be disallowed on the basis of moral grounds? Why is the media so interested in reporting results of brain imaging studies? What ethical lessons from the past can best inform the future of brain imaging? These compelling questions and many more are tackled by a distinguished group of contributors to this volume on neuroethics. The wide range of disciplinary backgrounds that the authors represent, from neuroscience, bioethics and philosophy, to law, social and health care policy, education, religion and film, allow for profoundly insightful and provocative answers to these questions, and open up the door to a host of new ones. The contributions highlight the timeliness of modern neuroethics today, and assure the longevity and importance of neuroethics for generations to come.

This book is open access under a CC BY 4.0 license. This book examines the concept of care and care practices in healthcare from the interdisciplinary perspectives of continental philosophy, care ethics, the social sciences, and anthropology. Areas addressed include dementia care, midwifery, diabetes care, psychiatry, and reproductive medicine. Special attention is paid to ambivalences and tensions within both the concept of care and care practices. Contributions in the first section of the book explore phenomenological and hermeneutic approaches to care and reveal historical precursors to care ethics. Empirical case studies and reflections on care in institutionalised and standardised settings form the second section of the book. The concluding chapter, jointly written by many of the contributors, points at recurring challenges of understanding and practicing care that open up the field for further research and discussion. This collection will be of great value to scholars and practitioners of medicine, ethics, philosophy, social science and history.

A TIMES ENVIRONMENT AND SCIENCE BOOK OF THE YEAR 2022 'Brilliant .. I cannot recommend this book strongly enough' - Henry Marsh, New Statesman (about The Idea of the Brain) A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction. But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers. By placing each phase of discovery, anticipation and fear in the context of over fifty years of attempts to master the natural world, Matthew Cobb, the Baillie-Gifford-shortlisted author of The Idea of the Brain, weaves the stories of science, history and culture to shed new light on our future. With the powers now at our disposal, it is a future that is almost impossible to imagine - but it is one we will create ourselves.

This volume congregates articles of leading philosophers about potentials and potentiality in all areas of philosophy and the empirical sciences in which they play a relevant role. It is the first encompassing collection of articles on the metaphysics of potentials and potentiality. Potentials play an important role not only in our everyday understanding of objects, persons and systems but also in the sciences. An example is the potential to become an adult human person. Moreover, the attribution of potentials involves crucial ethical problems. Bioethics makes references to the theoretical concept "potential" without being able to clarify its meaning. However, despite its relevance it has not been made subject of philosophical investigation. Mostly, potentials are regarded as a subspecies of dispositions. Whilst dispositions are a flourishing field of research, potentials as such have not come into focus. Potentials like dispositions are modal properties. But already a first glance at the metaphysics of potentials shows that concerning their ascription potentials are more problematic than dispositions since "potential" means that an entity has the potential to acquire a property in the future. Therefore, potentials involve a time structure of the entities in question that is much more complex than those of dispositions. This handbook brings this important concept into focus in its various aspects for the first time. It covers the history of the concept as well as contemporary systematic problems and will be of special interest for philosophers in the fields of general metaphysics, philosophy of science and ethics, especially bioethics. It will also be of interest to scientists and persons concerned with bioethical problems.

This book is aimed at analyzing the foundations of medical ethics by considering different moral theories and their implications for judgments in clinical practice and policy-making. It provides a review of the major types of ethical theory that can be applied to medical and bioethical issues concerning reproductive genetics. In response to the debate on the most adequate ethical doctrine to guide biomedical decisions, this book formulates views that capture the best elements in each, bearing in mind their differences and taking into account the specific character of medicine. No historically influential position in ethics is by itself adequate to be applied to reproductive decisions. Thus, this book attempts to offer a pluralistic approach to biomedical research and medical practice. One usually claims that there are some basic principles (non-maleficence, beneficence, confidentiality, autonomy, and justice) which constitute the foundations of bioethics and medical ethics. Yet these principles conflict with each other and one needs some criteria to solve these conflicts and to specify the scope of application of these principles. Exploring miscellaneous ethical approaches as introduced to biomedicine, particularly to reproductive genetics, the book shall elucidate their different assumptions concerning human nature and the relations between healthcare providers, recipients, and other affected parties (e.g. progeny, relatives, other patients, society). The book attempts to answer the question of whether the tension between these ethical doctrines generates conflict in the field of biomedicine or if these competing approaches could in some way complement each other. In this respect, lecturers and researchers in bioethics would be interested in this reading this book.

This book argues that legal theory provides a jumping-off point for the study of controversial topics related to the work of Practicing Healthcare Ethicists (PHEs). Healthcare ethics consultation has had a place in healthcare for many decades yet the nature of the work is not well understood by many of its critics as well as its defenders. PHEs have been described as compromised and ineffectual, politicised and undemocratic, and their promise to offer sound advice has been deemed irredeemably incoherent in the context of value pluralism. Legal theorists have long attended to the relationship between law and morality, and the supposed tension between democracy and the role of an expert judiciary. An appreciation that these debates are not unique to the practice of healthcare ethics can help PHEs to engage critics with a renewed confidence and some fresh approaches to perennial, and hitherto unproductive, arguments. This book will be of great interest to practicing healthcare ethicists, as well as those who rely upon their services (healthcare professionals and healthcare leaders, patients, and their families) as well as academics working in the broader field of bioethics.

In Rescuing Humanity, Willem H. Vanderburg reminds us that we have relied on discipline-based approaches for human knowing, doing, and organizing for less than a century. During this brief period, these approaches have become responsible for both our spectacular successes and most of our social and environmental crises. At their roots is a cultural mutation that includes secular religious attitudes that veil the limits of these approaches, leading to their overvaluation. Because their use, especially in science and technology, is primarily built up with mathematics, living entities and systems can be dealt with only as if their "architecture" or "design" is based on the principle of non-contradiction, which is true only for non-living entities. This distortion explains our many crises. Vanderburg begins to explore the limits of discipline-based approaches, which guides the way toward developing complementary ones capable of transcending these limits. It is no different from a carpenter going beyond the limits of his hammer by reaching for other tools. As we grapple with everything from the impacts of social media, the ongoing climate crisis, and divisive political ideologies, Rescuing Humanity reveals that our civilization must learn to do the equivalent if humans and other living things are to continue making earth a home.

This book questions how abortion laws can be regulated in a time when abortion rights are still subject to intense debate. It addresses objections to basing abortion law on considerations of moral risk, presents two anti-abortion arguments - the deprivation argument and the substance view - to demonstrate the risk of permitting abortion, and discusses the moral risk of restricting access to abortion when it may unjustifiably harm women. The author also shows how welfare states can address the negative effects of restrictive abortion laws by preventive, mitigative and compensatory measures. This is a thought-provoking and challenging book that will be of great interest to those considering abortion laws across the fields of medical ethics, bioethics, moral philosophy, law and politics.

This book charts technological developments from an African ethical perspective. It explores the idea that while certain technologies have benefited Africans, the fact that these technologies were designed and produced in and for a different setting leads to conflicts with African ethical values. Written in a simple and engaging style, the authors apply an African ethical lens to themes such as: The Fourth Industrial Revolution, the moral status of technology, technology and sexual relations, and bioethics and technology.

This book explores Kierkegaard’s significance for bioethics and discusses how Kierkegaard’s existential thinking can enrich and advance current bioethical debates.

This book offers a new perspective on advance directives through a combined legal, ethical and philosophical inquiry. In addition to making a significant and novel theoretical contribution to the field, the book has an interdisciplinary and international appeal. The book will help academics, healthcare professionals, legal practitioners and the educated reader to understand the challenges of creating and implementing advance directives, anticipate clinical realities, and preparing advance directives that reflect a higher degree of assurance in terms of implementation.

This book explores why animals, at some point, disappeared from the realm and scope of sociology. The role of sociology in the construction of a science of the 'human' has been substantial, building representations of the human sphere of life as unique. Within the sociological tradition however, animals have often been invisible, even non-existent. Through in-depth comparisons of the texts of prominent early sociologists Emile Durkheim and Edward Westermarck, Tuomivaara shows that despite this exclusion, representations of animals and human-animal relations were far more varied in early works than in the later sociological cannon. Addressing a significant gap in the interdisciplinary field of animal studies, Tuomivaara presents a close reading of the historical treatment of animals in the works of Durkheim and Westermarck to determine how the human-animal boundary was established in sociological theory. The diverse forms in which animals and 'the animal' appear in the works of early classical sociology are charted and explored, alongside the sociological themes that bring animals into these texts. Situated in contemporary theory, from critical animal studies to posthumanism, this important book lays the groundwork for a disciplinary shift away from this sharp human-animal dualism.

This book provides a bridge between the theory to practice gap in contemporary health care ethics. It explores the messiness of everyday ethical issues and validates the potential impacts on health care professionals as wounded healers who regularly experience close proximity to suffering and pain. This book speaks to why ethics matters on a personal level and how moral distress experiences can be leveraged instead of hidden. The book offers contributions to both scholarship and the profession. Nurses, physicians, social workers, allied health care professionals, as well as academics and students will benefit from this book.

An authoritative introduction to bioethics, "Life Choices "examines a comprehensive range of ethical questions and brings together some of the most probing and instructive essays published in the field.

Some of the articles are classics in the literature of bioethics, while others address current issues. Topics include moral decision making, abortion, euthanasia and assisted suicide, life-sustaining technologies, organ transplantation, reproductive technologies, and the allocation of health care resources.

This second edition features new sections on the goals and allocation of medicine and on the cloning of human beings. It also includes new articles on genetics, the duty to die, and ethical theory.

Written by the foremost authorities in bioethics, "Life Choices" provides a comprehensive introduction to the field. Instructors who have used the first edition as a text will welcome this new, updated edition. Scholars and health care practitioners will find it useful as a valuable reference on a wide range of bioethical issues.

This book is about the philosophy of de-extinction. To make an extinct species 'de-extinct' is to resurrect it by creating new organisms of the same, or similar, appearance and genetics. The book describes current attempts to resurrect three species, the aurochs, woolly mammoth and passenger pigeon. It then investigates two major philosophical questions such projects throw up. These are the Authenticity Question-'will the products of de-extinction be authentic members of the original species?'-and the Ethical Question-'is de-extinction something that should be done?' The book surveys and critically evaluates a raft of arguments for and against the authenticity or de-extinct organisms, and for and against the ethical legitimacy of de-extinction. It concludes, first, that authentic de-extinctions are actually possible, and second, that de-extinction can potentially be ethically legitimate, especially when deployed as part of a 'freeze now and resurrect later' conservation strategy.

Advances in genetics and related biotechnologies are having a profound effect on sport, raising important ethical questions about the limits and possibilities of the human body. Drawing on real case studies and grounded in rigorous scientific evidence, this book offers an ethical critique of current practices and explores the intersection of genetics, ethics and sport. Written by two of the world's leading authorities on the ethics of biotechnology in sport, the book addresses the philosophical implications of the latest scientific developments and technological data. Distinguishing fact from popular myth and science fiction, it covers key topics such as the genetic basis of sport performance and the role of genetic testing in talent identification and development. Its ten chapters discuss current debates surrounding issues such as the shifting relationship between genetics, sports medicine and sports science, gene enhancement, gene transfer technology, doping and disability sport. The first book to be published on this important subject in more than a decade, this is fascinating reading for anyone with an interest in the ethics of sport, bioethics or sport performance.

This book provides an in-depth ethical analysis of the right to health care by contrasting privatized with socialized approaches. It pays special attention to how a socialized approach can be implemented in the context of limited resources and offers a way of integrating allocation decisions at the policy level with institutional and hands-on decision-making. It also discusses how the right to health care translates into duties on part of the members of society. In an Appendix, it suggests how, in time of need, the TRIPS Agreement allows countries to side-step patent regulations that would otherwise raise the cost of patented healthcare products beyond what a particular society is able to afford. The book is of interest not only to scholars but also to healthcare policy makers, administrators and healthcare professionals, as well as to patients themselves.

This book includes a number of distinct religious and secular views on the anthropological, ethical and social challenges of reproductive technologies in the light of human rights and in the context of global bioethics. It includes contributions of bioethics experts from six major religions-Buddhism, Confucianism, Christianity, Islam, Hinduism and Judaism-as well as secular authors. The chapters include commentaries discussing the content cross-religious/secular tradition to give a comparative perspective. Not only the volume editors but also the contributing authors took part in reviewing each others' chapter making this a unique collected volume, not common in interreligious dialogue today. This text appeals to researchers and students working in the fields of bioethics and religious/secular studies.