This book examines the position of children who provide tissue to potentially save the life of another. It questions whether child donors of all ages have been treated appropriately and whether they are sufficiently protected in acting as tissue donors, and ultimately considers whether a new regulatory response is needed to benefit donor children. The book couples a legal exposition of the donor child's position with the medico-ethical reality of clinical practice. In recent years, a growing body of literature concerning the clinical experiences and outcomes for child donors has emerged. This book adds to this by examining another dimension - the regulatory frameworks at play. It examines the ethical arguments for and against children acting as tissue donors and provides an original analysis of the legal and non-legal regulatory frameworks governing children's participation in the United Kingdom, United States and Australia. It combines these doctrinal and theoretical approaches with insights into clinical practice gained from the results of qualitative research conducted with health professionals. The analysis inevitably explores the more general issues of children's right to make medical decisions, the role of parents in decision-making, the value of the best interests test and alternative (legal and ethical) standards, rights of participation of children before the courts, and the role of law and other forms of regulation in a clinical context.

The Legacies of Ursula K. Le Guin explores how Le Guin's fiction and essays have built a speculative ethical practice engaging indigenous knowledge and feminism, while crafting utopias in which human and other-than-human life forms enter into new relations. Her work also delineates new ways of making sense of the "science" of science fiction. The authors of this collection provide up-to-date discussions of well-known works as well as more experimental writings. Written in an accessible style, Legacies will appeal to any readers interested in literature, science fiction and fantasy, as well as specialists of science and technology studies, philosophy of science, ethics, gender studies, indigenous studies and posthumanism.

Despite the massive scale of global inequalities, until recently few political philosophers or bioethicists addressed their ethical implications. Questions of justice were thought to be primarily internal to the nation state. Over the last decade or so, there has been an explosion of interest in the philosophical issues surrounding global justice. These issues are of direct relevance to bioethics. The links between poverty and health imply that we cannot separate questions of global health from questions about fair distribution of global resources and the institutions governing the world order. Similarly, as increasing numbers of medical trials are conducted in the developing world, researchers and their sponsors have to confront the special problems of doing research in an unjust world, with corresponding obligations to correct injustice and avoid exploitation. This book presents a collection of original essays by leading thinkers in political theory, philosophy, and bioethics. They address the key issues concerning global justice and bioethics from two perspectives. The first is ideal theory, which is concerned with the social institutions that would regulate a just world. What is the relationship between human rights and the provision of health care? How, if at all, should a global order distinguish between obligations to compatriots and others? The second perspective is from non-ideal theory, which governs how people should behave in the unjust world in which we actually find ourselves. What sort of medical care should actual researchers working in impoverished countries offer their subjects? What should NGOs do in the face of cultural practices with which they deem unethical? If coordinated international action will not happen, what ought individual states to do? These questions have more than theoretical interest; their answers are of direct practical import for policymakers, researchers, advocates, NGOs, scholars, and others. This book is the first collection to comprehensively address the intersection of global justice and bioethical dilemmas.

This volume gives an overview on the currently debated ethical issues regarding advance directives from an international perspective. It focuses on a wider understanding of the known and widely accepted concept of patient self-determination for future situations. Although advance directives have been widely discussed since the 1980s, the ethical bases of advance directives still remain a matter of heated debates. The book aims to contribute to these controversial debates by integrating fundamental ethical issues on advance directives with practical matters of their implementation. Cultural, national and professional differences in how advance directives are understood by health care professions and by patients, as well as in laws and regulations, are pinpointed.

This volume brings together a set of critical essays on the thought of Professor Doctor H. Tristram Engelhardt Junior, Co-Founding Editor of the Philosophy and Medicine book series. Amongst the founders of bioethics, Professor Engelhardt, Jr. looms large. Many of his books and articles have appeared in multiple languages, including Italian, Romanian, Portuguese, Spanish, and Chinese. The essays in this book focus critically on a wide swath of his work, in the process elucidating, critiquing, and/or commending the rigor and reach of his thought. This volume compasses analyses of many different aspects of Engelhardt's work, including social and political philosophy, biopolitics, the philosophy of medicine, and bioethics. It brings together internationally known scholars to assess key elements of Engelhardt's work.

Drawing together interview material, medical publications, and first-hand accounts, this book shows that what is being remade in the burgeoning medical field of face transplantation is not only the lives of patients, but also the very ways that state institutions, surgeons, and families make sense of rights, claims for inclusion, and life itself.

Scientific research is often influenced by financial interests, political interests, or personal career interests of the scientists involved. For instance, the pharmaceutical giant Merck manipulated clinical trial data in order to make sure that data confirmed the safety of one of its products, Vioxx, in order to serve the company's short-term commercial interests. This case is obviously unacceptable. But why exactly is it unacceptable? One way to account for this judgment is on the basis of the ideal of purity. According to this ideal, scientific decision-making should be pure- that is, unaffected by financial interests, political interests, career interests, and so on. Although this ideal is questionable, many people (including philosophers of science) still hold on to it. In Interests and Epistemic Integrity in Science: A New Framework to Assess Interest Influences in Scientific Research Processes, Jan De Winter first argues that it is better to fully abandon the ideal of purity, then proposes an alternative ideal to assess interest influences in science: the ideal of epistemic integrity. He spells out and systematically defends a new concept of epistemic integrity, using it not only to analyze the Vioxx debacle, but also to identify unacceptable interest influences in aerospace science, climate science, and biology, and to explain exactly why these interest influences are unacceptable. These analyses make a compelling case for the new concept of epistemic integrity which will be interesting and useful for philosophers of science, scientists, engineers, science policymakers, and anyone else concerned about the integrity of science.

Joseph M. Boyle Jr. has been a major contributor to the development of Catholic bioethics over the past thirty five years. Boyle's contribution has had an impact on philosophers, theologians, and medical practitioners, and his work has in many ways come to be synonymous with analytically rigorous philosophical bioethics done in the Catholic intellectual tradition. Four main themes stand out as central to Boyle's contribution: the sanctity of life and bioethics: Boyle has elaborated a view of the ethics of killing at odds with central tenets of the euthanasia mentality, double effect and bioethics: Boyle is among the pre-eminent defenders of a role for double effect in medical decision making and morality, the right to health care: Boyle has moved beyond the rhetoric of social justice to provide a natural law grounding for a political right to health care; and the role of natural law and the natural law tradition in bioethics: Boyle's arguments have been grounded in a particularly fruitful approach to natural law ethics, the so-called New Natural Law theory. The contributors to BIOETHICS WITH LIBERTY AND JUSTICE: THEMES IN THE WORK OF JOSEPH M. BOYLE discuss, criticize, and in many cases extend the Boyle's advances in these areas with rigor and sophistication. It will be of interest to Catholic and philosophical bioethicists alike.

Behavioral neuroscience encompasses the disciplines of neurobiology and psychology to study mechanisms of behavior. This volume provides a contemporary overview of the current state of how ethics informs behavioral neuroscience research. There is dual emphasis on ethical challenges in experimental animal approaches and in clinical and nonclinical research involving human participants.

This book examines key trends in emerging strategic technologies and the implications for geopolitics and human dignity. Al-Rodhan argues that future evolution into transhumans is inevitable. In preparation, the global community is urged to establish strict moral and legal guidelines balancing innovation with the guarantee of dignity for all.

This open access book marks the first historical overview of the autism rights branch of the neurodiversity movement, describing the activities and rationales of key leaders in their own words since it organized into a unique community in 1992. Sandwiched by editorial chapters that include critical analysis, the book contains 19 chapters by 21 authors about the forming of the autistic community and neurodiversity movement, progress in their influence on the broader autism community and field, and their possible threshold of the advocacy establishment. The actions covered are legendary in the autistic community, including manifestos such as "Don't Mourn for Us", mailing lists, websites or webpages, conferences, issue campaigns, academic project and journal, a book, and advisory roles. These actions have shifted the landscape toward viewing autism in social terms of human rights and identity to accept, rather than as a medical collection of deficits and symptoms to cure.

This book examines the ethics of end of life care, focusing on the kinds of decisions that are commonly made in clinical practice. Specific attention is paid to the intensification of treatment for terminal symptoms, particularly pain relief, and the withdrawal and withholding of care, particularly life-saving or life-prolonging medical care. The book is structured into three sections. The first section contains essays examining end of life care from the perspective of moral theory and theology. The second sets out various conceptual terms and distinctions relevant to decision-making at the end of life. The third section contains chapters that focus on substantive ethical issues. This format not only provides for a comprehensive analysis of the ethical issues that arise in the context of end of life care but allows readers to effectively trace the philosophical, theological and conceptual underpinnings that inform their specific interests. This work will be of interest to scholars working in the area as well as clinicians, specialists and healthcare professionals who encounter these issues in the course of their practice.

In 2015 the UK became the first country in the world to legalise mitochondrial donation, a controversial germ line reproductive technology to prevent the transmission of mitochondrial disease. Dimond and Stephens track the intense period of scientific and ethical review, public consultation and parliamentary debates preceeding the decision. They draw on stakeholder accounts and public documents to explore how patients, professionals, institutions and publics mobilised within 'for' and 'against' clusters, engaging in extensive promissory, emotional, bureaucratic, ethical, embodied and clinical labour to justify competing visions of an ethical future. They describe how this decision is the latest iteration of a UK sociotechnical imaginary in which the further liberalization of human embryo research and use is rendered legitimate and ethical through modes of consultation and permissive but strictly regulated licensing. Overall, this book presents a timely, multi-dimensional, and sociological account of a globally significant landmark in the history of human genetics, and will be relevant to those with an interest in genetics, Science, Technology and Society, the sociology of medicine, reproductive technology, and public policy debate.

This book offers ethical and political approaches to issues that nonhuman animals face. The recent 'political turn' in interspecies ethics, from ethical to political approaches, has arisen due to the apparent lack of success of the nonhuman animal movement and dissatisfaction with traditional approaches. Current works largely present general positions rather than address specific issues and principally rely on mainstream approaches. This book offers alternative positions such as cosmopolitan, libertarian, and left humanist thought, as well as applying ethical and political thought to specific issues, such as experimentation, factory farming, nonhuman political agency, and intervention. Presenting work by theorists and activists, insights are offered from both ethics and politics that impact theory and practice and offer essential considerations for those engaging in interspecies ethics within the political turn era.

This work sets the stage regarding debates about paternalism and health care for years to come. The anthology is organized around four parts: i) The concept of paternalism and theoretical issues regarding the idea of anti-paternalism, ii) strategies for justifying different forms of paternalism, iii) paternalism in psychiatry and psychotherapy, iv) paternalism and public health, and v) paternalism and reproductive medicine. Medical paternalism was arguably one of the main drivers of debates in medical ethics and has led to a wide acknowledgement of the value of patient autonomy. However, more recent developments in health care, such as the increasing significance of public health measures and the commercialization of medical services, have led to new social circumstances and hence to the need to rethink issues regarding paternalism. This work provides an invaluable source for many scholars and practitioners, since it deals in new and original ways with one of the main and oldest issue in health care ethics.

Shaw addresses the 'ethical turn' in contemporary sociological thinking, by exploring the contribution of sociology and the social sciences to bioethical debates about morality and tissue exchange practices.

This anthology of original essays by leading thinkers in the field gathers together in one place voices from diverse theological and practical commitments. Unlike other publications on Jewish bioethics, it adopts an explicitly pluralistic stance. The book addresses tension between the 'quality of life' and the 'sanctity of life' issues, and will be of interest to lay readers, graduate students of bioethics, and rabbis.

Biomedical Ethics for Engineers provides biomedical engineers with a new set of tools and an understanding that the application of ethical measures will seldom reach consensus even among fellow engineers and scientists. The solutions are never completely technical, so the engineer must continue to improve the means of incorporating a wide array of societal perspectives, without sacrificing sound science and good design principles.
Dan Vallero understands that engineering is a profession that profoundly affects the quality of life from the subcellular and nano to the planetary scale. Protecting and enhancing life is the essence of ethics; thus every engineer and design professional needs a foundation in bioethics. In high-profile emerging fields such as nanotechnology, biotechnology and green engineering, public concerns and attitudes become especially crucial factors given the inherent uncertainties and high stakes involved. Ethics thus means more than a commitment to abide by professional norms of conduct. This book discusses the full suite of emerging biomedical and environmental issues that must be addressed by engineers and scientists within a global and societal context. In addition it gives technical professionals tools to recognize and address bioethical questions and illustrates that an understanding of the application of these measures will seldom reach consensus even among fellow engineers and scientists.
- Working tool for biomedical engineers in the new age of technology
- Numerous case studies to illustrate the direct application of ethical techniques and standards
- Ancillary materials available online for easy integration into any academic program

Diplomacy, Funding and Animal Welfare is a practical guide to the best diplomatic and negotiation practices needed to convince governments and international institutions to effectively protect animals, which also introduces new approaches to fundraising. Animal protection advocates are prepared for speaking to diplomats and government officials in any setting, and to combatants in war zones. The book mainly focuses on approaching local and national governments, the United Nations system, the international Red Cross movement and systems related to other international organizations that can help animals, often in surprising ways. The reader will learn the rules of "diplomatic protocol", and much about the rules and procedures of major international bodies. To provide balance and real world relevance, the guide draws on a compilation of the author's extensive activities across a range of development, animal welfare, emergency management and climate issues in government and in the NGO world, as well as interviews with scholars and officials from NGOs, diplomatic missions, the United Nations, the Red Cross, governments and corporations.

The research field of biobanks and tissue research is highly promising. Many projects around the globe are involved in the collection of human tissue and health data for research purposes. These initiatives are driven by the perspective of decisive breakthroughs in the knowledge of the genetic pathways involved in widespread diseases. However, there are considerable ethical and legal challenges to be considered as well. These challenges encompass the use of body material for research purposes, the misuse of genetic and other health data by third parties, trust in science and medicine, concerns regarding privacy, use of genetic data for forensic applications by the state and the police, and regulatory issues. This volume is divided into three parts: the inclusion of the public, the rights of donors and patients, examples and recommendations for the future of tissue research. It presents a comprehensive overview of the most important topics in the field by renowned scholars in medical ethics and biolaw.

This book puts the ethics, policy and politics of stem cells into context in a way that helps readers understand why past and current issues have developed the way they have and what the implications are for their work going forward. It also addresses emerging issues as the field progresses towards clinical and industrial uses. While there is a superabundance of material on the ethics of embryo use and questions of embryonic "personhood," there is little that covers what practicing scientists and managers need to know in order to plan and execute responsible research. Furthermore, researchers funded by the NIH are required to have ethics training as a condition of the grant. As such, this book is an essential resource to all of these pre-professional students whether they plan to move into industry, government or academia.

This anthology of original essays by leading thinkers in the field gathers together in one place voices from diverse theological and practical commitments. Unlike other publications on Jewish bioethics, it adopts an explicitly pluralistic stance. The book addresses tension between the 'quality of life' and the 'sanctity of life' issues, and will be of interest to lay readers, graduate students of bioethics, and rabbis.

Synthetic biology is becoming one of the most dynamic new fields of biology, with the potential to revolutionize the way we do biotechnology today. By applying the toolbox of engineering disciplines to biology, a whole set of potential applications become possible ranging very widely across scientific and engineering disciplines. Some of the potential benefits of synthetic biology, such as the development of low-cost drugs or the production of chemicals and energy by engineered bacteria are enormous. There are, however, also potential and perceived risks due to deliberate or accidental damage. Also, ethical issues of synthetic biology just start being explored, with hardly any ethicists specifically focusing on the area of synthetic biology. This book will be the first of its kind focusing particularly on the safety, security and ethical concerns and other relevant societal aspects of this new emerging field. The foreseen impact of this book will be to stimulate a debate on these societal issues at an early stage. Past experiences, especially in the field of GM-crops and stem cells, have shown the importance of an early societal debate. The community and informed stakeholders recognize this need, but up to now discussions are fragmentary. This book will be the first comprehensive overview on relevant societal issues of synthetic biology, setting the scene for further important discussions within the scientific community and with civil society.

This book addresses the debate usually tagged as being about 'markets in human body parts' which is antagonistically divided into pro-market and anti-market positions. The author provides a set of propositions about how to approach this and shows a way out of the concrete impasse of it. Assumptions about markets and bodies that characterize this debate are analyzed and described while the author argues that these assumptions are in fact constitutive for exchanges of human bodily material - but in unacknowledged ways. It is concluded that what we need is a different analytical approach to better understand the mechanisms at play when organizations exchange organs, tissues and cells for use in transplantation and fertility medicine.

At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches. By 2003 and the fourth edition, it was generally agreed that biopharmaceuticals were producing major opportunities for new cancer therapies. Cancer biotherapy has now truly matured into the fourth modality of cancer treatment. This fifth revised edition describes the tremendous progress that has been made in recent years using biologicals in cancer treatment.

This book summarizes an evolving science and a rapidly changing medical practice in biotherapy. In this new millennium, it is now possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for a patient s personalized cancer treatment. This was first envisioned in the 1987 initial edition of this textbook and is now a new and popular approach to cancer treatment. Some forms of cancer biotherapy use the strategy of tumor stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes.

This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this fifth edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients for researchers and clinicians to explore and quickly apply these new opportunities in cancer biotherapy."