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Books > Academic & Education > Professional & Technical > Biochemistry
If you investigate biological systems and might use mass
spectrometry in your research but need to know more about it, this
book is for you. It introduces the fundamental concepts of mass
spectrometry and how mass spectrometers work. It also presents
recent advancements particularly interesting to bio-researchers in
an easy-to-understand manner that does not require extensive
background in chemistry, math, or physics.
Immunoassay procedures (isotopic and non-isotopic) have become one of the single most important techniques in present-day diagnostic medicine. This book is designed as an introductory test for the staff of clinical research laboratories who conduct or intend to conduct such techniques, and will be of great value to the clinicians who make use of such services. The volume takes a three-pronged approach in it's in-depth presentation: explanation of the basic principles and applications of radioimmunoassays and non-isotopic immunoassays; practical illustrations of the various steps involved in immunoassays; discussion of the problems and pitfalls in immunoassays and how to avoid them. This fifth revised edition is a worthy successor to it's predecessors in this famous "Laboratory Techniques" series.
Part I covers modern advances in the determination of
The results of today's genome projects promise enormous medical and agricultural benefits and point to a new predictive approach to the conduct of future research in biology. Biocomputing: Informatics and Genome Projects represents a survey of the needs and objectives of genome projects as of the early 1990's. It provides the groundwork necessary to understand genome-related informatics, including computational and database storage objectives. The book covers four general areas: automated laboratory notebooks, nucleic acid sequence analysis, protein structure, and database activities.
Dry chemistry has been accepted as an important technology in medical laboratories for many years. Many evaluations of this technology have been undertaken by reputable clinical laboratories, the results of which were excellent when compared with conventional wet chemistry analysis. This book contains a detailed overview of the current knowledge in the field of dry chemistry both in the physicians' office laboratories and large medical laboratories. The results from many evaluation studies are presented, as is data from interference studies which complete the descriptions of many dry chemistry methods. A detailed description of various commercially available dry chemistry systems such as Ektachem, Reflotron, Seralyzer, Cobas Ready, Drichem, Opus and Stratus are also included. This book effectively describes the current state-of-the-art technology and knowledge and succeeds in filling the gap in information in this important field of clinical chemistry science. Originally published as 'Trockenchemie' by Georg Thieme
Verlag,
The series Practical Methods in Electron Microscopy, edited by
Audrey M. Glauert has an international reputation as
Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ESR is the only technique which has the potential for direct detection of radicals but in biological systems even these must be trapped by a spin-trapping agent. Thus most investigations involve recognition of indicators of the presence of radicals in vivo or "FOOTPRINTS" of radical-mediated damage.
Aging occurs at the level of individual cells, a complex interplay between intrinsic "programming" and exogenous "wear and tear," with genetically-determined cellular capacity to repair environmentally-induced DNA damage playing a central role in the rate of aging and its specific manifestations. In 12 chapters, "The Role of DNA Damage and Repair in Cell Aging" provides an intellectual framework for aging of mitotic and post-mitotic cells, describes a variety of model systems for further studies, and reviews current concepts of DNA responses and their relationship to the phenomenon of aging.
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