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Books > Academic & Education > Professional & Technical > Biochemistry
An expanded, up-to-date resource for students and researchers, "The
Dictionary of Cell & Molecular Biology, Fifth Edition,"
provides clear and concise definitions needed for laboratory study.
With over 12,000 entries and a breadth of terms across bioscience,
including plant molecular biology, microbiology and biotechnology,
this revision reflects the changes in the research over the past
few years. The latest edition of "The Dictionary of Cell and
Molecular Biology" maintains its outstanding reputation as an
authoritative, clear, and accessible reference with short,
cross-referenced definitions of important technical terminology.
The detection and measurement of the dynamic interactions of
proteins within the living cell are critical to our understanding
of cell physiology and pathophysiology. With FRET microscopy and
spectroscopy techniques, basic and clinical scientists can make
such measurements at very high spatial and temporal resolution. But
sources of background information about these tools are very
limited, so this book fills an important gap. It covers both the
basic concepts and theory behind the various FRET microscopy and
spectroscopy techniques, and the practical aspects of using the
techniques and analyzing the results. The critical tricks for
obtaining a good FRET image and precisely quantitating the signals
from living specimens at the nanomolecular level are explained.
Valuable information about the preparation of biological samples
used for FRET image analysis is also provided.
Retaining the introductory flavor of the now classic First Edition,
this revision includes all the latest techniques in the field. New
information on methods of radio tag harnessing, new sections on
satellite tracking techniques and new types of data analysis are
all included. Still the only comprehensive, up-to-date,
introduction to this fundamental technique for wildlife and
behavioral biologists.
The third edition of this innovative work again provides a unique
perspective on the clinical discovery process by providing input
from experts within the NIH on the principles and practice of
clinical research. Molecular medicine, genomics, and proteomics
have opened vast opportunities for translation of basic science
observations to the bedside through clinical research. As an
introductory reference it gives clinical investigators in all
fields an awareness of the tools required to ensure research
protocols are well designed and comply with the rigorous regulatory
requirements necessary to maximize the safety of research subjects.
Complete with sections on the history of clinical research and
ethics, copious figures and charts, and sample documents it serves
as an excellent companion text for any course on clinical research
and as a must-have reference for seasoned researchers.
The growing area of peptide and protein therapeutics research is
of paramount importance to medical application and advancement. A
needed reference for entry level researchers and researchers
working in interdisciplinary / collaborative projects, Peptide and
Protein Delivery addresses the current and emerging routes for
delivery of therapeutics. Covering cerebral delivery, pulmonary
delivery, transdermal delivery, intestinal delivery, ocular
delivery, parenteral delivery, and nasal delivery, this resource
offers an overview of the main routes in therapeutics. Researchers
across biochemistry, pharmaceutical, molecular biology, cell
biology, immunology, chemistry and biotechnology fields will find
this publication invaluable for peptide and protein laboratory
research.
Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences. Articles written and edited by experts in the field
This handbook provides the first comprehensive overview of the
emerging field of glycomics, defined as the study of all complex
carbohydrates in an organism or cell ("the glycome"). Beginning
with analytic approaches and bioinformatics, this work provides a
detailed discussion of relevant databases, data integration, and
analysis. It then moves on to a discussion of specific model
organism and pathogen glycomes followed by therapeutic approaches
to human disorders of glycosylization. Structure and function of
glycomes are included along with state-of-the-art technologies and
systems approaches to the analysis of glycans.
Much like the "Chicago Manual of Style," "The Manual of Scientific
Style" addresses all stylistic matters in the relevant disciplines
of physical and biological science, medicine, health, and
technology. It presents consistent guidelines for text, data, and
graphics, providing a comprehensive and authoritative style manual
that can be used by the professional scientist, science editor,
general editor, science writer, and researcher. Organization and directives designed to assist readers in finding the precise usage rule or convention A focus on American usage in rules and formulations with noted differences between American and British usage Differences in the various levels of scientific discourse addressed in a variety of settings in which science writing appears Instruction and guidance on the means of improving clarity, precision, and effectiveness of science writing, from its most technical to its most popular
Description
This volume reviews the techniques Forster Resonance Energy Transfer (FRET) and Fluorescence Lifetime Imaging Microscopy (FLIM) providing researchers with step by step protocols and handy hints and tips. Both have become staple techniques in many biological and biophysical fields.
Jeff's Views provide witty, insightful, and thought-provoking looks
into the life of a modern scientist. From starting off to letting
go, Gottfried ("Jeff") Schatz leads us through the trials and
triumphs of scientific life. With his tongue firmly in his cheek,
and his humour always intact, the Austrian essayist leads us
through the confusing and seemingly insurmountable hill that is the
career path of European scientists. In addition to giving useful
insights into how to get funding, give seminars, and still find
time to make that leading edge scientific discovery, Jeff explores
the philosophical dimensions of recent biological breakthroughs
such as the sequencing of the human genome, the evolution of
sensory receptors, and cellular suicide.
"Recent Events in the Psychology of Aging" documents the successful
integration of aging into the mainstream of psychology. Leading
psychologists present overviews of the key issues and research
findings on mainstream topics. These include cognitive
neuroscience, visual attention, learning, memory and cognition, as
well as personality and happiness. The intersection of aging
content with mainstream psychology is also prominent in the areas
of emotions, personality, and social psychology as seen in the
chapters on subjective well-being, emotional development,
self-esteem and personality trajectories.
Collectively, the chapters in this work will provide the reader
with novel insight into the inter-relationships of the function of
different organelles in the sequences of events that lead to
cellular dysfunction and degeneration in the aging human
population. The chapters are rich in information for cell and
molecular biologists pursuing studies of the different diseases
covered. In addition, the clinician will find value in
understanding mechanisms underlying age-related disease as such an
understanding will lead to novel therapeutic approaches for an
array of age-related diseases.
An accompanying volume (Volume 6) in this series presents
strategies of cellular invasion from the viewpoint of the microbe.
This volume of "Advances in Cell Aging and Gerontology" critically reviews the rapidly advancing area of telomerase research with a focus at the molecular and cellular levels. The clearly established function of telomerase is to maintain chromosome ends during successive rounds of cell division by adding a six base DNA repeat on to the telomeric ends of chromosomes. As presented in the chapters of this volume, the mechanisms that regulate telomerase expression and activity are complex. Moreover, emerging data suggest additional roles for telomerase in the regulation of cell differentiation and survival.
This book focuses on emerging themes in the molecular mechanisms of
calcium signal transduction through calmodulin-regulated pathways.
It provides the reader with selected examples and experimental
precedents that underlie current models of cell regulation through
calmodulin-regulated pathways and their linkage with other
regulatory pathways.
This is the fourth volume in the series, aimed at those wishing to stay abreast of developments in the mechanisms and synthetic applications of 1,3-dipolar cycloaddition reactions.
This newly revised and updated edition of Radiation Biophysics
provides an in-depth description of the physics and chemistry of
radiation and its effects on biological systems. Coverage begins
with fundamental concepts of the physics of radiation and
radioactivity, then progresses through the chemistry and biology of
the interaction of radiation with living systems. The Second
Edition of this highly praised text includes major revisions which
reflect the rapid advances in the field. New material covers recent
developments in the fields of carcinogenesis, DNA repair, molecular
genetics, and the molecular biology of oncogenes and tumor
suppressor genes. The book also includes extensive discussion of
the practical impact of radiation on everyday life.
Living organisms exhibit specific responses when confronted with
sudden changes in their environmental conditions. The ability of
the cells to acclimate to their new environment is the integral
driving force for adaptive modification of the cells. Such
adaptation involves a number of cellular and biochemical alteration
including metabolic homeostasis and reprogramming of gene
expression. Changes in metabolic pathways are generally short-lived
and reversible, while the consequences of gene expression are a
long-term process and may lead to permanent alternation in the
pattern of adaptive responses.
Radiological Imaging: The Theory of Image Formation, Detection, and Processing is intended to prepare the student to do research in radiological imaging, to teach general image science within a radiographic context, and to help the student gain fluency with the essential analytical tools of linear systems theory and the theory of stochastic processes that are applicable to any imaging system. The book contains chapters devoted to the discussion of linear systems, Poisson processes, analysis of radiographic systems, radiographic image detectors, and the various aspects of three-dimensional or tomographic imaging. Computed tomography, psychophysics, and scattered radiation and its effect on image are also elucidated. Radiology technicians will find the book very invaluable.
Written with corporate regulatory compliance officers, health and
safety managers, loss control managers, and human resource
specialists in mind, this book offers workplace-tested strategies
for meeting the health and safety needs of a modern corporation.
Emphasizing the practical means of achieving compliance with OSHA
regulations, this book also provides a unique assessment of the
more extensive factors that influence the management of workplace
health and safety. The integration of practical regulation
strategies with corporate objectives is particularly relevant to
graduate curricula in business management, public policy, and
occupational medicine.
DNA Structure and Function, a timely and comprehensive resource, is
intended for any student or scientist interested in DNA structure
and its biological implications. The book provides a simple yet
comprehensive introduction to nearly all aspects of DNA structure.
It also explains current ideas on the biological significance of
classic and alternative DNA conformations. Suitable for graduate
courses on DNA structure and nucleic acids, the text is also
excellent supplemental reading for courses in general biochemistry,
molecular biology, and genetics.
This series provides a variety of different discussions on topics within the field of growth factors and cytokines in health and disease.
This volume deals with aspects of the cytoskeleton in different
cell types and also describe examples of changes in the
cytoskeleton which occur during various pathological states. These
studies bring the exciting area of cytoskeleton research into the
domain of medical science.
This is the third volume in a series on membrane protein transfer. Membrane protein transport underlies the topological disposition of many proteins within cells and it is this disposition that allows for the co-ordination of the central cellular processes, such as metabolism. |
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