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Microarray Technology in Practice (Paperback)
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Microarray Technology in Practice (Paperback)
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Description
Using chips composed of thousands of spots, each with the
capability of holding DNA molecules corresponding to a given gene,
DNA microarray technology has enabled researchers to measure
simultaneously gene expression across the genome. As with other
large scale genomics approaches, microarray technologies are
broadly applicable across disciplines of life and biomedical
sciences, but remain daunting to many researchers. This guide is
designed to demystify the technology and inform more biologists
about this critically important experimental technique.
.Provides a basic overview of microarray technology and available
platforms for those unfamiliar with the technology
.Includes detailed discussion of experimental design and analysis
of microarray experiments, giving first-time users valuable
information that can be tailored to their own research needs
.Provides discussion of such hot areas as ChIP (chromatin
immunoprecipitation) with hybridization to DNA arrays,
microarray-based comparative genomic hybridization (CGH), and cell
and tissue arrays
Expert author team highlights the utility of the technology using
examples from human health and disease--e.g., malaria and cancer
diagnostics.
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