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Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development > Reproductive medicine > Embryology

Prenatal Development, 5th: Culture Techniques - Applicability for Studies on Prenatal Differentiation and Toxicity (Hardcover,... Prenatal Development, 5th: Culture Techniques - Applicability for Studies on Prenatal Differentiation and Toxicity (Hardcover, Reprint 2019)
D. Neubert, H.J. Merker
R5,540 Discovery Miles 55 400 Ships in 10 - 15 working days
Larsen's Human Embryology (Paperback, 6th edition): Gary C. Schoenwolf, Steven B. Bleyl, Philip R. Brauer, Philippa H... Larsen's Human Embryology (Paperback, 6th edition)
Gary C. Schoenwolf, Steven B. Bleyl, Philip R. Brauer, Philippa H Francis-West
R2,041 Discovery Miles 20 410 Ships in 12 - 19 working days

Offering a well-organized, straightforward approach to a highly complex subject, Larsen's Human Embryology, 6th Edition, provides easy-to-read, comprehensive coverage of human embryonic development for today's students. It integrates anatomy and histology with cellular and molecular mechanisms, focusing on both normal development and congenital anomalies. Highly illustrated with superb drawings and photographs, it features a strong clinical focus based on the most up-to-date scientific discoveries and understanding.Contains new information on gene editing via CRISPr technology, organoids and the study of human disease, transcription factors and signaling pathways, and single cell sequencing. Includes clinical scenarios that describe prevention, diagnosis, and treatment of human birth defects and disease. Features a superior art program, online animations, and high-quality drawings and photographs throughout-ideal for today's visual learners. * Includes a strong clinical emphasis through the use of Clinical Tasters, Embryology in Practice, and In the Clinic sections. Provides additional information on mechanisms of development and research approaches and strategies to establish these mechanisms with In the Research Lab sections. Begins each chapter with an overview of main points as well as a graphical summary, with key terms listed in bold type. Covers the embryology information that today's medical students need to know for Board exams, clinics, and more, in a readable, straightforward manner. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access 50 narrated animations, multiple-choice questions, and all of the text, figures, and references from the book on a variety of devices.

Essentials of Oral Histology and Embryology - MENA Adapted Reprint (Paperback): Daniel J Chiego Essentials of Oral Histology and Embryology - MENA Adapted Reprint (Paperback)
Daniel J Chiego; Edited by Sausan Al Kawas
R1,553 Discovery Miles 15 530 Ships in 12 - 19 working days

Master the essentials of oral biology with patient-centered approach. New illustrations and discussions of emerging issues keep you updated with advances in the dental professions and patient care. Written by Daniel J. Chiego Jr., and Professor Sausan Al Kawas both are experienced educators and researchers in oral histology and embryology, this book provides the basic science you need to succeed in the classroom and in clinical practice.

Embryology - Theory and Practice (Hardcover): Bin Wu, Huai L. Feng Embryology - Theory and Practice (Hardcover)
Bin Wu, Huai L. Feng
R3,321 Discovery Miles 33 210 Ships in 10 - 15 working days
Embryo Implantation - Molecular, Cellular and Clinical Aspects (Hardcover, 1999 ed.): Daniel D. Carson Embryo Implantation - Molecular, Cellular and Clinical Aspects (Hardcover, 1999 ed.)
Daniel D. Carson
R4,546 Discovery Miles 45 460 Ships in 10 - 15 working days

Embryoimplantationisaremarkableandcomplexprocess. Approachesde- velopedfromthefieldsofcellanddevelopmentalbiology,immunology, andmolecularbiologyhavegreatlyenhancedourabilitytostudythe sharedaswellasuniquefeaturesofembryo-uterineinteractions. Impres- siveandcriticalgroundworkhasbeenlaidbyalargeanddedicatedarray ofendocrinologists,reproductivebiologists,andanatomists. Thesestudies havesetthestagetoutilizesensitiveandsophisticatedtechniquestode- tectandmodulateproteinandgeneexpression. Justasthesymbiosisofmother andfetusiscriticalforthemaintenanceofpregnancy,soisthesynergyamong investigatorsfrommanydisciplines,bothinbasicandclinicalarenas,keyto unravelingthemysteriesofimplantationandplacentation. Alargegroupof contributorsinthisfieldhadtheopportunitytomeetanddiscussthestateof thisartwiththesupportofSeronoSymposiaUSA,Inc. Whileitisneverpos- sibletobringtogethereveryonewhohasplayedanimportantrole,itwas, nonetheless,bothexcitingandgratifyingtohavesomanycolleaguestogether forthisevent. Inthechaptersthatfollow,thehighlightsofthismeetingarepresented assummarizedbytheindividualpresentersofsevendifferentsessions. The topichasbeenconsideredfromthebroadsocialandethicalimplications ofmoderninvitrofertilizationandassistedreproductivetechnologiesto detailedmolecularcontrolsovereventsthatoccurduringembryonicdevel- opment,uterinepreparationforimplantation,andplacentalorganogenesis. Thesechaptersdemonstratethesignificantandrapidprogressbeingmade inthisfieldofbiologyandmedicine. Atthesametime,theyshowthat muchmoreneedstobedonetounderstandandfullyappreciatethispro- cess. Lessonslearnedfromthiseffortcanbeexpectedtocontinuetopro- videinsightsintoother,relatedfields. Ofthemanycontributorstoour understandingoftheprocessofimplantation,nonehavehadalargerim- pactthanourcolleague,AllenEnders. Dr. Endershasplayedaparamount roleindevelopingthebasicunderstandingofthecellbiologicalprocesses vii VIII Preface underlyingimplantationandplacentationinmanyspecies,includinghu- mans. Hecontinuestocontributeandguidethoughtintheseareas. The participantsofthissymposiumrecognizedDr. Enders'impressivecontribu- tionsbyholdingthiseventinhishonor. DANIELD. CARSON * Contents Preface vii Contributors xiii PartI. Development and Future ofHuman In Vitro Fertilization and Embryo Implantation I. ImplantationintheHumanasViewedbyCanonLaw, CivilLaw,andNaturalReason 3 HOWARDW. JONES, JR. , RICHARDA. MCCORMICK, AND SUSAN L. CROCKIN 2. TheImpactofMaternalAgeandOvarianAge onImplantationEfficiency...12 STEVEN SPANDORFER AND ZEV ROSENWAKS Part II. CellularAspects ofImplantation 3. VascularInvasionDuringImplantationandPlacentation 23 ALLEN C. ENDERS AND THOMASN. BLANKENSHIP 4. OxygenRegulatesHumanCytotrophoblastProliferation, Differentiation,andInvasion:Implicationsfor EndovascularInvasioninNormalPregnancy andPreeclampsia 39 OLGA GENBACEV,YAN ZHOU, MICHAEL T. McMASTER, JOHNW. LUDLOW, CAROLINEH. DAMSKY, AND SUSAN1. FISHER 5. Embryo-MaternalInteractionsafterDiapause inaMarsupial 54 MARILYNB. RENFREE AND GEOFFREY SHAW IX x Contents 6. CellularInteractionsandtheCysteineProteinases intheProcessofMouseImplantation 67 BRUCE BABIARZ, SUZANNE AFONSO, ANDLINDA ROMAGNANO Part III. HormonalRegulation 7. NovelSteroid-RegulatedMarkersofImplantation 83 INDRANIC. BAGCHI 8. MolecularSignalinginImplantation 92 SANJOYK. DAS, BIBHASHC. PARIA, AND SUDHANSU K. DEY 9. IdentificationofProgesterone-RegulatedGenes intheUterus 107 CINDEER. FUNK, BERTW. O'MALLEY, AND FRANCESCO1. DEMAYO PartIV. MolecularMarkersofReceptivity 10. MucinsProvideaBarriertoEmbryoImplantation 123 MARYM. DESOUZA, GULNARA. SURVEYOR, XINHUI ZHOU, JoANNE JULIAN, ANDDANIELD. CARSON II. PotentialInvolvementofTrophinin,Bystin, andTastininEmbryoImplantation 132 MICHIKON. FUKUDA, DAITA NADANO,NAO SUZUKJ, AND JUN NAKAYAMA 12. OsteopontininHumanEndometrium: ARoleinEndometrialReceptivityand EmbryoImplantation? 141 CHRISTOS COUTIFARJS,AKINYINKA OMIGBODUN, PIOTR ZIOLKIEWICZ, AND JOHN HOYER PartV. TrophoblastFactors 13. TheRabbitasaModelforImplantation: InVivoandInVitroStudies 151 LORENH. HOFFMAN,D. RACHEL BREINAN, AND GARETHL. BLAEUER 14. RegulationofTrophoblastEndocrineFunction: ThePlacentaDoesItsOwnThingTranscriptionally...161 JEROMEF. STRAUSSIII ANDLEE-CHUANKAo Contents XI 15. TranscriptionFactorsRegulatingtheDifferentiation oftheTrophoblastCellLineage 167 IANC. SCOTTANDJAMESC.

The Human Brain during the First Trimester 6.3- to 10.5-mm Crown-Rump Lengths - Atlas of Human Central Nervous System... The Human Brain during the First Trimester 6.3- to 10.5-mm Crown-Rump Lengths - Atlas of Human Central Nervous System Development, Volume 2 (Paperback)
Shirley A. Bayer, Joseph Altman
R1,545 Discovery Miles 15 450 Ships in 12 - 19 working days

1) Classic anatomical atlases 2) Detailed labeling of the earliest phases of prenatal nervous system development 3) Appeals to neuroanatomists, developmental biologists, and clinical practioners. 4) Persistent relevance - archival reference work that will be usable for decades.

Egg - A Dozen Ovatures (Hardcover): Lizzie Stark Egg - A Dozen Ovatures (Hardcover)
Lizzie Stark
R680 Discovery Miles 6 800 Ships in 12 - 19 working days

Lizzie Stark takes readers on a witty, revealing and delightful journey through the natural and cultural history of the egg, exploring its deep symbolism, innumerable uses and metabolic importance in twelve dazzling specimens. From Mali to Finland, Stark looks at cultures that find the world's origins in an egg. Decorated by Ukrainians, an oracle for Greeks, the impetus behind gang wars and flown into space, the egg-whether of chickens, murres or ostriches-has taken on mythic proportions, all the while serving as a humble ingredient in fancy dishes. Stark even writes Jacques Pepin's biography through the lens of the egg dishes he served. Egg is also about Stark's fascination with this delicate ovoid-both her myriad attempts to create a perfect omelette and her fraught relationship to the ova in her body. Filled with colourful characters and fascinating morsels, Egg is a playful, informative and surprising history that guarantees you'll never take the egg for granted again.

Patent Foramen Ovale Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia (Paperback):... Patent Foramen Ovale Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia (Paperback)
M.Khalid Mojadidi, Bernhard Meier, Jonathan M. Tobis
R3,504 Discovery Miles 35 040 Ships in 12 - 19 working days

Patent Foramen Ovale (PFO) Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia is a complete reference covering the association between PFO and numerous medical conditions. It provides a background on the topic including embryology, anatomy, and physiology. This book fully examines the diagnosis and imaging assessment of PFO and discusses the data linking PFO to various clinical pathologies. It details technical aspects of PFO closure and includes perspectives on future outlooks and where the field is headed in terms of device closure indications. This is a complete reference book for cardiologists, interventional cardiologists, neurologists, pulmonologists, general practitioners, medical professionals, and researchers who are interested in PFO-associated pathologies, technical aspects, safety, and future outlooks of PFO device closure.

Notch Signaling in Embryology and Cancer - Molecular Biology of Notch Signaling (Hardcover, 2nd ed. 2020): Joerg Reichrath,... Notch Signaling in Embryology and Cancer - Molecular Biology of Notch Signaling (Hardcover, 2nd ed. 2020)
Joerg Reichrath, Sandra Reichrath
R2,901 Discovery Miles 29 010 Ships in 10 - 15 working days

This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch's flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway's role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch's role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books - Notch Signaling in Embryology and Notch Signaling in Cancer - this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.

Centennial History of the Carnegie Institution of Washington: Volume 5, The Department of Embryology (Hardcover, New): Jane... Centennial History of the Carnegie Institution of Washington: Volume 5, The Department of Embryology (Hardcover, New)
Jane Maienschein, Marie Glitz, Garland E. Allen
R4,082 Discovery Miles 40 820 Ships in 12 - 19 working days

Founded in 1914, the Department of Embryology of the Carnegie Institution of Washington has made an unparalleled contribution to the biological understanding of embryos and their development. Originally much of the research was carried out through experimental embryology, but by the second half of the twentieth century, tissue and cell cultures were providing histological information about development, and biochemistry and molecular genetics have taken center stage. This final volume in a series of five histories of the Carnegie Institution of Washington provides a history of embryology and reproductive biology spanning a hundred years. It provides important insights into the evolution of both scientific ideas and the public perception of embryo research, concluding with a reflection on current debates.

Embryonic Stem Cells: Differentiation Processes and Alternatives (Hardcover): Jack Collins Embryonic Stem Cells: Differentiation Processes and Alternatives (Hardcover)
Jack Collins
R2,592 R2,361 Discovery Miles 23 610 Save R231 (9%) Ships in 10 - 15 working days
The Human Brain during the First Trimester 6.3- to 10.5-mm Crown-Rump Lengths - Atlas of Human Central Nervous System... The Human Brain during the First Trimester 6.3- to 10.5-mm Crown-Rump Lengths - Atlas of Human Central Nervous System Development, Volume 2 (Hardcover)
Shirley A. Bayer, Joseph Altman
R4,019 Discovery Miles 40 190 Ships in 12 - 19 working days

1) Classic anatomical atlases 2) Detailed labeling of the earliest phases of prenatal nervous system development 3) Appeals to neuroanatomists, developmental biologists, and clinical practioners. 4) Persistent relevance - archival reference work that will be usable for decades.

Religion, Medicine and the Human Embryo in Tibet (Paperback): Frances Garrett Religion, Medicine and the Human Embryo in Tibet (Paperback)
Frances Garrett
R1,614 Discovery Miles 16 140 Ships in 12 - 19 working days

This book explores the cultural history of embryology in Tibet, in culture, religion, art and literature, and what this reveals about its medicine and religion. Filling a significant gap in the literature this is the first in-depth exploration of Tibetan medical history in the English language. It reveals the prevalence of descriptions of the development of the human body - from conception to birth - found in all forms of Tibetan religious literature, as well as in medical texts and in art. By analysing stories of embryology, Frances Garrett explores questions of cultural transmission and adaptation: How did Tibetan writers adapt ideas inherited from India and China for their own purposes? What original views did they develop on the body, on gender, on creation, and on life itself? The transformations of embryological narratives over several centuries illuminate key turning points in Tibetan medical history, and its relationship with religious doctrine and practice. Embryology was a site for both religious and medical theorists to contemplate profound questions of being and becoming, where topics such as pharmacology and nosology were left to shape secular medicine. The author argues that, in terms of religion, stories of human development comment on embodiment, gender, socio-political hierarchy, religious ontology, and spiritual progress. Through the lens of embryology, this book examines how these concerns shift as Tibetan history moves through the formative 'renaissance' period of the twelfth through to the seventeenth centuries.

Molecular Signaling in Spermatogenesis and Male Infertility (Paperback): Rajender Singh Molecular Signaling in Spermatogenesis and Male Infertility (Paperback)
Rajender Singh
R1,520 Discovery Miles 15 200 Ships in 12 - 19 working days

Spermatogenesis involves the coordination of a number of signaling pathways, which culminate into production of sperm. Its failure results in male factor infertility, which can be due to hormonal, environmental, genetic or other unknown factors. This book includes chapters on most of the signaling pathways known to contribute to spermatogenesis. Latest research in germ cell signaling like the role of small RNAs in spermatogenesis is also discussed. This book aims to serve as a reference for both clinicians and researchers, explaining possible causes of infertility and exploring various treatment methods for management through the basic understanding of the role of molecular signaling. Key Features Discusses the signaling pathways that contribute to successful spermatogenesis Covers comprehensive information about Spermatogenesis at one place Explores the vital aspects of male fertility and infertility Explains the epigenetic regulation of germ cell development and fertility Highlights the translational opportunities in molecular signaling in testis

Embryology - An Illustrated Colour Text (Paperback, 2nd edition): Barry Mitchell, Ram Sharma Embryology - An Illustrated Colour Text (Paperback, 2nd edition)
Barry Mitchell, Ram Sharma
R900 Discovery Miles 9 000 Ships in 12 - 19 working days

If you're taking an undergraduate or postgraduate medical courses, or similar courses in other related disciplines, this is the book for you. Embryology is a concise and highly illustrated text, covering only the descriptions you really need to know. An appreciation of embryology is essential to understand topological relationships in gross anatomy and to explain many congenital anomalies. Text in concise Illustrated Colour Text style, so core information on embryology can be quickly recognised and digested. Clear full colour diagrams and pictures make the embryological concepts clear and easily assimilated. Clinical boxes highlight essential points of importance to medical students.

Religion, Medicine and the Human Embryo in Tibet (Hardcover): Frances Garrett Religion, Medicine and the Human Embryo in Tibet (Hardcover)
Frances Garrett
R4,778 Discovery Miles 47 780 Ships in 12 - 19 working days

This book explores the cultural history of embryology in Tibet, in culture, religion, art and literature, and what this reveals about its medicine and religion. Filling a significant gap in the literature this is the first in-depth exploration of Tibetan medical history in the English language. It reveals the prevalence of descriptions of the development of the human body - from conception to birth - found in all forms of Tibetan religious literature, as well as in medical texts and in art. By analysing stories of embryology, Frances Garrett explores questions of cultural transmission and adaptation: How did Tibetan writers adapt ideas inherited from India and China for their own purposes? What original views did they develop on the body, on gender, on creation, and on life itself? The transformations of embryological narratives over several centuries illuminate key turning points in Tibetan medical history, and its relationship with religious doctrine and practice. Embryology was a site for both religious and medical theorists to contemplate profound questions of being and becoming, where topics such as pharmacology and nosology were left to shape secular medicine. The author argues that, in terms of religion, stories of human development comment on embodiment, gender, socio-political hierarchy, religious ontology, and spiritual progress. Through the lens of embryology, this book examines how these concerns shift as Tibetan history moves through the formative 'renaissance' period of the twelfth through to the seventeenth centuries.

Human Fertilisation and Embryology - Reproducing Regulation (Hardcover): Kirsty Horsey, Hazel Biggs Human Fertilisation and Embryology - Reproducing Regulation (Hardcover)
Kirsty Horsey, Hazel Biggs
R4,925 Discovery Miles 49 250 Ships in 12 - 19 working days

Relevant to students, academics and practitioners across the globe, this original volume highlights contemporary issues associated with assisted reproduction and embryology and critically analyzes the law surrounding human reproduction in the light of case law and technological developments since the Human Fertilisation and Embryology Act (HFE Act) Act was passed in 1990. Tackling issues from an interdisciplinary perspective, the authors identify and evaluate areas that have provoked intense public and academic debate as well as those where further or renewed regulation is needed. Focusing primarily on the legal and ethical issues involved in regulating this area in the UK, which is at the forefront of developing legislation in this area, this book has international relevance as many countries have used the UK as a model for their own legislation. This text is suitable for a broad range of readers, including legal academics, law students and practitioners interested in the areas of medical/healthcare law and ethics, bioethics and moral philosophy, family law, sociology and reproductive medicine and genetics.

Concise Clinical Embryology: an Integrated, Case-Based Approach (Paperback): Mark G. Torchia, T.V.N. Persaud Concise Clinical Embryology: an Integrated, Case-Based Approach (Paperback)
Mark G. Torchia, T.V.N. Persaud
R1,068 Discovery Miles 10 680 Ships in 12 - 19 working days

Written by the authors of the renowned embryology textbooks The Developing Human and Before We Are Born, Concise Clinical Embryology: An Integrated, Case-Based Approach offers essential, high-yield information and high-quality clinical cases to illustrate key principles of embryology and their relevance to everyday practice. Ideally tailored to the needs of today's medical students and medical courses, this concise text clearly explains how embryology relates to other medical disciplines and its importance in safe, effective clinical practice. Abundant illustrations throughout help you grasp highly visual concepts quickly and easily. Provides easily digestible, clinically oriented coverage of human development, establishing key principles in a week-by-week, stage-by-stage approach, before moving on to fetal organ development by body system. Includes clinical cases and follow-up questions in each chapter that help relate key principles to everyday practice, aid in problem-based learning, and offer review for exam preparation. Covers the latest advances in embryology, including normal and abnormal embryogenesis, causes of birth defects, and the role of genes in human development. Contains superb illustrations from cover to cover, including diagnostic images, full color figures, histology, and more. Summarizes molecular biology highlights throughout the text. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access 18 3D animations with expert commentary, plus all of the text, figures, and references from the book on a variety of devices.

Human Embryology Made Easy (Paperback): Abdul Hamid Rana Human Embryology Made Easy (Paperback)
Abdul Hamid Rana
R1,702 Discovery Miles 17 020 Ships in 12 - 19 working days

This book is a synopsis of the key facts and concepts of human development. It is intended for students who are taking a human embryology course. The book includes the underlying mechanisms involved in clinically important congenital anomalies that will prove useful to medical and nursing.

A Dictionary of Congenital Malformations and Disorders (Paperback): J. Gibson, Oliverira Potparic, O. Potparic A Dictionary of Congenital Malformations and Disorders (Paperback)
J. Gibson, Oliverira Potparic, O. Potparic
R1,970 Discovery Miles 19 700 Ships in 12 - 19 working days

This is a complete, medically reliable dictionary of congenital malformations and disorders. As the authors explain, Down syndrome is the only common congenital disorder; the other defects and disorders are rare or very rare, some having been reported fewer than 20 times worldwide.This dictionary covers them all. Examples: Aagenaes syndrome is due to congenital hypoplasia of lymph vessels, which causes lymphedema of the legs and recurrent cholestasis in infancy, and slow progress to hepatic cirrhosis and giant-cell hepatitis with fibrosis of the portal tracts. Acrocallosal syndrome is characterized by total or partial absence of the corpus callosum, craniofacial dysmorphism, polydactyly, and severe mental retardation. Other features can be retinal pigmentation anomalies, optic atrophy, strabismus, nystagmus, cleft lip and palate, cardiovascular anomalies, hernia, abnormal nipples, and fits. Acrodysostosis is characterized by prenatal growth deficiency, brachycephaly, de formities of the humerus, radius and ulna, short and broad hands, hypoplastic maxilla, and mental retardation.

Human Embryology Made Easy (Hardcover): Abdul Hamid Rana Human Embryology Made Easy (Hardcover)
Abdul Hamid Rana
R3,600 Discovery Miles 36 000 Ships in 12 - 19 working days

This book is a synopsis of the key facts and concepts of human development. It is intended for students who are taking a human embryology course. The book includes the underlying mechanisms involved in clinically important congenital anomalies that will prove useful to medical and nursing.

Perinatal Biochemistry (Hardcover): Robert H. Knopp, Emilio Herrera Perinatal Biochemistry (Hardcover)
Robert H. Knopp, Emilio Herrera
R14,244 Discovery Miles 142 440 Ships in 12 - 19 working days

Intrauterine development and birth constitute an uninterrupted sequence of events that have a molecular physiologic background. Perinatal Biochemistry presents a comprehensive review of this subject. Specific topics addressed include maternal metabolism during pregnancy, maternal insulin resistance, embryonic and fetal metabolism and fuel consumption, the fetal pancreas, growth factors, brain metabolism, and biochemical adaptations to early extrauterine life. The book will be useful to biochemists and physiologists interested in perinatology; clinicians working in areas related to maternal health, gestational development, and delivery; gynecologists, neonatologists; pediatricians; endocrinologists; and internists.

Fetal Growth and Development (Hardcover): Richard Harding, Alan D. Bocking Fetal Growth and Development (Hardcover)
Richard Harding, Alan D. Bocking
R4,818 Discovery Miles 48 180 Ships in 12 - 19 working days

The fetus occupies a critical phase during human development. It is at this stage when the body systems that will support us throughout our lives begin to face up to the challenge of life outside the womb. While the fetus can demonstrate a remarkably robust response to challenges in the uterus, it is also an exquisitely sensitive phase of development. It is now well recognized that disturbances to the materno-fetal environment can influence and even undermine our state of health well into adulthood. This exciting new publication provides a valuable insight into fetal growth and development across all the main body systems, and examines the influence of the materno-fetal environment on adult-onset diseases. This text contains additional chapters on the embryo, placenta, and parturition, to insure that this is a fully self-contained introduction. This book is written by world-renowned experts from leading centers of excellence and will be an invaluable introduction for students of medicine, reproductive biology, and human biology.

Preservation of Human Oocytes - From Cryobiology Science to Clinical Applications (Hardcover): Andrea Borini, Giovanni Coticchio Preservation of Human Oocytes - From Cryobiology Science to Clinical Applications (Hardcover)
Andrea Borini, Giovanni Coticchio
R5,852 Discovery Miles 58 520 Ships in 12 - 19 working days

Oocyte cryopreservation entails important potential advantages for human IVF, offering a less ethically disputable alternative to embryo cryopreservation, simplifying and making safer oocyte donation, and giving an opportunity for fertility preservation to women at risk of premature ovarian failure as an effect of genetic factors or chemo- or radiotherapies. Oocyte cryopreservation could also meet the expectations of women wishing to preserve their fertility for social reasons. In the last few years, advances in cryopreservation methodologies have dramatically improved the efficiency of oocyte cryopreservation, leading to the birth of over a thousand babies and challenging the supremacy of embryo cryopreservation as the preferred form of fertility preservation. This text has been conceived with the aim of offering a comprehensive view of the state of the art of oocyte cryopreservation. It covers fundamental concepts of low temperature storage (controlled rate slow cooling and vitrification), aspects of oocyte physiology relevant to the process of cryopreservation, essential biological and clinical evidence, and ethical implications of oocyte cryopreservation, thereby providing a complete overview of progress in this strategy in assisted reproduction.

Notch Signaling in Embryology and Cancer - Notch Signaling in Embryology (Hardcover, 1st ed. 2020): Joerg Reichrath, Sandra... Notch Signaling in Embryology and Cancer - Notch Signaling in Embryology (Hardcover, 1st ed. 2020)
Joerg Reichrath, Sandra Reichrath
R2,880 Discovery Miles 28 800 Ships in 10 - 15 working days

This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch's role in the development of the embryo to the Notch signaling pathway's role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch's role in senescence, the regulation of Notch signaling by microRNAs, Notch's role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books - Molecular Biology of Notch Signaling and Notch Signaling in Cancer - this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.

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