The Fundamentals of Human Embryology covers embryonic development, with a unique focus on adult anatomy. Its goal is to impart to students a comprehensive overview of how the human embryo forms, not only as a basis for the student of human anatomy, but also as a link to abnormalities they may encounter in their clinical careers. Extensively illustrated with labeled line drawings, now enlarged for better visibility, this concise manual will meet the needs of both undergraduate and postgraduate students in the Human Sciences. Special features include: * Separate chapters on the neural crest, the skull and osteogenesis * In-depth coverage of head and neck embryology, including the development of the tooth, for students of dentistry, and speech and audiology In this Second Edition of the manual at the request of students and teachers, the authors have made the following changes: * Increased the size of the diagrams * Revised the text to comply with the Federative International Committee on Anatomical Terminology changes to the Terminologia Embryologica * Altered the sequencing of some topics to allow the development to flow more logically * Included an appendix of coloured photographs of congenital abnormalities to help students form a more realistic idea of developmental abnormalities.

Concise, clearly written, and vibrantly illustrated, Langman's Medical Embryology, 15th Edition, makes complex embryology concepts approachable to help you build the clinical understanding essential to your success in medical practice, nursing, or other health professions. Hundreds of full-color illustrations clarify the stages of embryonic development with rich detail, and engaging learning features, clinical examples, and online review questions ready you for the challenges ahead on your exams and in clinical practice. NEW! Medical Embryology Animations, now included with the purchase of the print book, allow users to visualize the stages of human development and master the corresponding anatomical relationships. UPDATED! Clinical Correlates boxes reinforce clinically relevant content through realistic case-based scenarios you're likely to encounter in practice. UPDATED! More than 400 full-color illustrations, micrographs, and clinical images clarify key aspects of embryonic development in vivid detail. UPDATED! Clinical vignette and USMLE-style multiple-choice questions, available via digital access, with answers provide valuable self-assessment and strengthen your test-taking confidence. Problems to Solve boost your critical thinking capabilities. End-of-Chapter Summaries detail key stages of development, terms, and clinical conditions for each chapter at a glance.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Different technologies have been introduced to improve management of labor. To date there is no single text that aims at covering all these technologies that address different problems and issues in labor management. The book reviews new technologies and devices aimed to improve labor management and outcomes. These diverge between looking at a better way to use fetal heart rate monitors (that are used in 90% of labours); using new monitors to detect the <1% of babies that are damaged in labor and account for 99% of the medico-legal costs in labor; and early detection of non-progressive labors that complicate 30-50% of labors. This is the only book about all these technologies from the perspectives of new devices and technologies in labor.

This book provides the first clinically comprehensive and practical approach to ethical challenges in perinatal medicine.The first chapter introduces and explains the professional responsibility model of perinatal ethics.The professional responsibility model is based on the medical ethics of two major physician-ethics in the history of Western medical ethics, Dr. John Gregory (1724-1773) of Scotland and Dr. Thomas Percival (1740-1804) of England.The professional responsibility model is used to articulate the ethical concept of the fetus as a patient and to operationalize the ethical principles of beneficence and respect for autonomy.The book provides practical guidance for clinical judgment and decision making with patients about the responsible clinical management of the wide range of issues encountered by perinatologists in clinical practice and research.Topics included: periviability; feticide; intrapartum management; maternal-fetal conflict; innovation for fetal benefit; research for fetal benefit; non-aggressive obstetric management; managing the transition from pregnancy to birth; destructive procedures such as cephalocentesis; critical care for the pregnant patient; home birth; patient-choice cesarean delivery; neonatal care as a trial of management; and setting limits on neonatal care on the basis of clinical judgments of futility.

Assisted reproductive technologies have had a profound impact on biomedical research through transgenic animals, food supply and production, as wells as genetic gain of domestic species, and treatment of human infertility. While significant advances in embryo culture have occurred over the last few decades. In Embryo Culture: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to study human embryo culture. These include emerging methods and the impact of embryo culture on epigenetics and offspring health is presented to set the stage for future research and laboratory application involving embryo culture. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Embryo Culture: Methods and Protocols seeks to aid scientists in the further study of this crucially important field of embryology and assisted reproductive technologies.

The central question of this book is whether or not particular cell entities of human origin ought to be considered human beings. The answer is crucial for making moral decisions for or against research and experimentation. Experts in the field discuss the production of embryonic-like pluripotent stem cells by altered nuclear transfer, parthenogenesis and reprogramming of adult somatic cells. They thoroughly analyse the biological and moral status of different cell entities, such as human stem cells, embryos and human-animal hybrid embryos, and make a decisive step towards establishing final criteria for what constitutes a human being. The topic is challenging in nature and of broad interest to all those concerned with current bioethical thought on embryonic human life and its implications for society.

The advent of robotic surgery brought a rise in the proportion of minimally invasive surgery in gynecology. This book provides a practical guide to this innovative field. First it introduces the basics of robotic surgery and then focuses on specific gynecology-related surgeries. Gynecologists currently practicing robotic surgery as well as those who would like to include robotic surgery in their practice will benefit greatly from this book.

Drawing on a wide range of interviews and primary and secondary sources, this book investigates the dynamic interactions between national regulatory formation and the global biopolitics of regenerative medicine and human embryonic stem cell science.

To celebrate the Center for Perinatal Biology s 40th Anniversary, an illustrious group gathered at Loma Linda University in February 2013. That gathering of experts and this volume of the proceedings are a tribute to the founder of the Center, Lawrence D. Longo, M.D. These chapters present contributions from individuals who in some way or another were influenced by Dr. Longo. Covering a wide range of topics, and illustrating the diversity of thinking and scientific interests, these proceedings address basic science through to clinical problems in the developmental programming of health and disease. "

Carl Edward Sagan's (1934-1996) one of the famous quotation was "Who are we? We find that we live on an insignificant planet of a humdrum star lost in a galaxy tucked away in some forgotten corner of a universe in which there are far more galaxies than people." From past to date, well-known molecules, enzymes, proteins, lipids and carbohydrates are studied in the pathogenesis of several diseases both as a diagnostic/prognostic biomarker and therapeutic agent. The underlying mechanism of unexplained diseases and failure of therapies are frequently studied with well-known biomarkers, but remain unclear in many cases. As Dr. Sagan said other keys are still waiting to be known in some forgotten corner of a body universe, we find strength to propose that one of them can be the growth factor with cytokine activity named "Midkine" This book summarizes the extensive up-to-date literature overeview with the lastest work of experts about midkine in a detailed format that conveys its role as both a pathologic factor and therapeutic agent.

This atlas comprises a complete and extensive exposure of the spatial and temporal aspects of human cardiac development as seen with scanning electron microscopy. Apart from serving as a unique overview on cardiac development in the human embryo, this atlas gives an updated morphological reference of cardiac embryology for topographic correlation and enables the projection of experimental results in animals to the human situation.

This book grew out ofmy interest in what is often called "the immunological paradox ofpregnancy." How is it possible that the fetus-halfofwhosegenetic apparatuscomesfrom thefather and is foreign to the mother-can survive to term? This is a question that intrigues all immunologists. For me, it has been of interest ever since I heard a lecture on the subject in medical school, long before I thought ofbecoming a "professional immunologist." Indeed, the question ofthe immunological aspect of fetal survival (or demise) should be of interest to any biologist or physician. The question becomes broader ifone considers the immunologic relations between motherand fetus, because they represent a unique symbiotic union. Whatimmunologic problemsinthemothermayaffecttheoffspring, and isitpossiblethatfetal immunology willaffectthe mother? Finally, there is the question ofwhether immunology is important in recur- rent spontaneous abortion. Every authorowes the reader a general oversightofthe book in hand, indicating the terrain to be covered, and, by inference, the territory that will not be explored. 1. This is primarily a book for clinicians. I will only men- tion animal experiments and data in passing, and as they may illuminate a clinical problem or observation. 2. The interest here is the immunology ofmaterno--fetal re- lations, once a pregnancy has begun. Therefore, I will notcover immunological aspects ofsterility, nor touch on the immunological approaches to controlling fer- tility, i.e., "contraceptive vaccines." 3. This is a book mainly concerned with pathogenesis.

Offering a well-organized, straightforward approach to a highly complex subject, Larsen's Human Embryology, 6th Edition, provides easy-to-read, comprehensive coverage of human embryonic development for today's students. It integrates anatomy and histology with cellular and molecular mechanisms, focusing on both normal development and congenital anomalies. Highly illustrated with superb drawings and photographs, it features a strong clinical focus based on the most up-to-date scientific discoveries and understanding.Contains new information on gene editing via CRISPr technology, organoids and the study of human disease, transcription factors and signaling pathways, and single cell sequencing. Includes clinical scenarios that describe prevention, diagnosis, and treatment of human birth defects and disease. Features a superior art program, online animations, and high-quality drawings and photographs throughout-ideal for today's visual learners. * Includes a strong clinical emphasis through the use of Clinical Tasters, Embryology in Practice, and In the Clinic sections. Provides additional information on mechanisms of development and research approaches and strategies to establish these mechanisms with In the Research Lab sections. Begins each chapter with an overview of main points as well as a graphical summary, with key terms listed in bold type. Covers the embryology information that today's medical students need to know for Board exams, clinics, and more, in a readable, straightforward manner. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access 50 narrated animations, multiple-choice questions, and all of the text, figures, and references from the book on a variety of devices.

Master the essentials of oral biology with patient-centered approach. New illustrations and discussions of emerging issues keep you updated with advances in the dental professions and patient care. Written by Daniel J. Chiego Jr., and Professor Sausan Al Kawas both are experienced educators and researchers in oral histology and embryology, this book provides the basic science you need to succeed in the classroom and in clinical practice.