Biosensors are finding increasing applications in different areas. Over the last few years the areas where biosensors may be used effectively has increased dramatically. This book like the previous four books on analyte-receptor binding and dissociation kinetics by this author addresses the often neglected area. The kinetics of binding and dissociation in solution to appropriate receptors immobilized on biosensor surfaces occurs under diffusional limitations on structured surfaces. The receptors immobilized on the biosensor surface contribute to the degree of heterogeneity on the sensor chip surface.
The fractal analysis examples presented throughout the book provide a convenient means to make quantitative the degree of heterogeneity present on the sensor surface, and relates it to the binding and dissociation rate coefficients. The fractal dimension is a quantitative measure of the degree of heterogeneity present on the biosensor surface. The book emphasizes medially-oriented examples. The detection of disease-related analytes is also emphasized. The intent being that if intractable and insidious diseases are detected earlier, they will be controlled better, eventually leading to a better prognosis. Chapter 3 is a new chapter that emphasizes enhancing the relevant biosensor performance parameters such as sensitivity, stability, selectivity, response time, etc.
As usual, as done in previous books by this author, the last chapter provides an update of the economics involved in biosensors, and the difficulties encounters in starting-up a biosensor company.
- Modelling of binding and dissociation kinetics of analyte-receptor reactions on biosensor surfaces: provides physical insights into these reactions occurring on biosensor surfaces. Very few researchers even attempt to analyze the kinetics of these types of reactions.
- Fractal analysis used to model the binding and dissociation kinetics: original and unique approach.
- Economic analysis provided in the last chapter: helps balance the book; besides providing much-needed information not available in the open literature.
- Emphasis on improving biosensor performance parameters: helps make biosensors better.
- Empahsis on medically-related analytes: helps in prognosis of diseases.

This book covers supply chain and logistics, production and manufacturing systems as well as human factors. Topics such as applications to procurements from suppliers, suppliers developments and relationships with suppliers are reported. The techniques and tools applied to production processes, such as, machinery maintenance and quick changeover, are described in detail. The book also presents human factors as the main component in the industrial engineering field, reporting some successful teamwork organizations for improvements and applied ergonomics, among others.

This book introduces intelligent manufacturing system planning, design, and implementation, through the deep integration of the Internet, big data, artificial intelligence, and manufacturing process, to promote the transformation and upgrading of enterprises. This book shows the implementation of intelligent manufacturing process with 12 benchmarking enterprises, discusses the planning, implementation, and control of intelligent manufacturing system technology and method of theory, and analyzes the five hierarchies of intelligent manufacturing system, the five stages of life cycle, and five kinds of intelligent depth. The content can cultivate the reader's vocational ability to develop intelligent solutions and implementation based on complex, uncertain environment needs. This book will be interesting and useful to a wide readership in the various fields of management, information science, and engineering science.

This book is focused on the challenges of digital transition in building construction, and potential solutions through the use of multi-criteria analysis. It provides clear explanations of proposed approaches from both a theoretical and practical point of view, including augmented reality and user-reporting. New Approaches for Multi-Criteria Analysis in Constructions begins by explaining classic multi-criteria analysis methods, such as Analytic Hierarchy Processes and the Simos-Roy-Figueira method, before moving on to discuss Augmented Reality - Decision Making. This new approach provides a tool to investigate user's perceptions, and utilises an interactive experience of the real-world environment combined with classic methods to provide a large amount of visual information. Finally, a detailed guide to user-reporting is presented. Offering new possibilities for applying multi-criteria analysis in a simpler, faster and more accessible way, this book supports analysis which considers users experience and perception. Architects, engineers, researchers and practitioners will be able to utilise augmented reality environments, multi-criteria analysis and user reporting for the building design choices, supply selection, maintenance strategies, risk and complex performance assessment.

T Level Engineering is written to cover the core elements of the new T Level Engineering qualifications. It provides essential information for T Level Engineering students and teachers, and will be useful as the student moves into higher education or an apprenticeship. The new T Level qualifications offer a realistic option to A Level and other vocational options. After completing a T Level in Engineering the student has a number of options including university courses and higher level apprenticeships. This book is written in an accessible fashion, no previous knowledge of engineering or technology is required, as all the technical terms are readily explained and a detailed glossary and list of abbreviations are included. Whether you are a student, tutor, or work placement manager you will surely find this book an enjoyable read and a handy reference book on your shelf. Andrew Livesey, MA, CEng is an experienced lecturer in engineering at Ashford College, Kent. He was a member of the DfE committee responsible for developing the T Levels and is a T Level Ambassador. His Routledge publications include: Basic Motorsport Engineering (2011), Advanced Motorsport Engineering (2012), The Repair of Vehicle Bodies (2018), Practical Motorsport Engineering (2018), Bicycle Engineering and Technology (2021) and Motorcycle Engineering (2021).

This book treats important topics in "Acoustic Echo and Noise Control" and reports the latest developments. Methods for enhancing the quality of transmitted speech signals are gaining growing attention in universities and in industrial development laboratories. This book, written by an international team of highly qualified experts, concentrates on the modern and advanced methods.

Discusses the concepts of mechanical, thermal, and thermodynamic equilibrium and their applications. Covers the molecular basis for internal energy, entropy, thermodynamic equilibrium, and reversibility. Enables the reader to model irreversibility and determine the net loss in performance of a thermal system compared to an idealized system and approach an ideal one. Demonstrates entropy as a path independent property by use of reversible heat engines and reversible heat pumps interacting with a process between two states, the environment and the reservoir. Covers the role of reversibility from a thermodynamics standpoint and relates it to other areas, such as gas dynamics, combustion, propulsion, power plant engineering, and engines.

This book gathers extended versions of the best papers presented at the Global Joint Conference on Industrial Engineering and Its Application Areas (GJCIE), held as a hybrid event on October 29-30, 2022, in/from Istanbul Technical University. Continuing the tradition of previous volumes, it highlights recent developments of industrial engineering at the purpose of using and managing digital and intelligent technologies for application to a wide range of field, including manufacturing, healthcare, e-commerce and sustainable development. A special emphasis is given to engineering methods and strategies for managing pandemics and reducing their adverse effects on businesses.

This book examines the burgeoning revolution in the construction industry known as Construction 4.0, the attendant need for re-skilling human resources, and key stakeholders' roles in developing the required skills for Construction 4.0. It views the lack of 21st-century skills and skills gap in the industry as significant challenges limiting the uptake and implementation of Construction 4.0 technologies, especially in developing countries. In order to determine the skills required, this book examines the critical technologies of Construction 4.0, such as building information modelling (BIM), robotic construction, 3D printing and drones, which have transformed the construction industry, thereby creating digital, intelligent and sustainable construction solutions. Furthermore, the book considers the benefits, risks and relevant skills required to implement Construction 4.0 technologies.

Transportation Engineering: Theory, Practice and Modeling, Second Edition presents comprehensive information related to traffic engineering and control, transportation planning and evaluation of transportation alternatives. The book systematically deals with almost the entire transportation engineering area, offering various techniques related to transportation modeling, transportation planning, and traffic control. It also shows readers how to use models and methods when predicting travel and freight transportation demand, how to analyze existing transportation networks, how to plan for new networks, and how to develop traffic control tactics and strategies. New topics addressed include alternative Intersections, alternative interchanges and individual/private transportation. Readers will also learn how to utilize a range of engineering concepts and methods to make future transportation systems safer, more cost-effective, and "greener". Providing a broad view of transportation engineering, including transport infrastructure, control methods and analysis techniques, this new edition is for postgraduates in transportation and professionals needing to keep up-to-date with the latest theories and models.

This book examines the implementation of science, technology and innovation (STI) policy in eight Latin American countries and the different paths these policies have taken. It provides empirical evidence to examine the extent to which STI policies are contributing to the development of the region, as well as to the solution of market failures and the stimulus of the region s innovation systems.

Since the pioneering work of Solow (1957), it has been recognized that innovation is critical for economic growth both in developed and in less-developed countries. Unfortunately Latin America lags behind world trends and although over the last 20 years the region has established a more stable and certain macroeconomic regime, it is also clear that these changes have not been enough to trigger a process of innovation and productivity to catch-up. Against this rather grim scenario there is some optimism emerging throughout the region. After many years of inaction the region has begun to invest in science, technology and engineering once again. Furthermore, after many changes in innovation policy frameworks, there is now an emerging consensus on the need for a solution to coordination failures that hinder the interaction between supply and demand.

Offering an informative and analytic insight into STI policymaking within Latin America, this book can be used by students, researchers and practitioners who are interested in the design and implementation of innovation policies. This book also intends to encourage discussion and collaboration amongst current policy makers within the region.

Military robots and other, potentially autonomous robotic systems such as unmanned combat air vehicles (UCAVs) and unmanned ground vehicles (UGVs) could soon be introduced to the battlefield. Look further into the future and we may see autonomous micro- and nanorobots armed and deployed in swarms of thousands or even millions. This growing automation of warfare may come to represent a major discontinuity in the history of warfare: humans will first be removed from the battlefield and may one day even be largely excluded from the decision cycle in future high-tech and high-speed robotic warfare. Although the current technological issues will no doubt be overcome, the greatest obstacles to automated weapons on the battlefield are likely to be legal and ethical concerns. Armin Krishnan explores the technological, legal and ethical issues connected to combat robotics, examining both the opportunities and limitations of autonomous weapons. He also proposes solutions to the future regulation of military robotics through international law.

The continuous search for efficiency gains and the goal of attaining a sustainable competitive advantage have steadily increased the volume of goods and services procured globally from third party vendors. In this context, named as "the next wave of globalization", the offshoring phenomenon has stimulated research and political debates. With the rise of services offshoring, international value chain disaggregation for services has reached a formerly unknown scale. Also, it is increasingly complex transactions, requiring a higher degree of qualification, which are becoming subject to offshoring as well. The Offshoring Challenge: Strategic Design and Innovation for Tomorrow's Organization features selected chapters by an international research community on the topic of offshoring. All potential business models from offshore outsourcing to third party providers are covered, from cooperative arrangements to internal organizational set-ups including captive offshore centers. Contributions have significant insights regarding: the increasing offshoring of knowledge-intensive services; the offshoring process; business models incorporating offshoring; the hidden costs of offshoring; and the administration of offshoring activities within firms The book is aimed at a broad audience of scholars, students and practitioners in the fields of strategy, international business and operations management.

This book gathers the latest advances, innovations, and applications in the field of construction design and management, as presented by researchers and engineers at the International Conference Industrial and Civil Construction 2021, held in Belgorod, Russia, on January 18-19, 2021. It covers highly diverse topics, including building materials, building constructions, structural mechanics and theory of structures, industrial and civil construction, environmental engineering and sustainability. The contributions, which were selected by means of a rigorous international peer-review process, highlight numerous exciting ideas that will spur novel research directions and foster multidisciplinary collaborations.

Technology has created innovative new prospects for manufacturing industries with Industry 4.0 and has helped further the growth of the manufacturing sector. This book focuses on the next stage, which is Industry 5.0, and the steps in taking automation to that next level by increasing processes and operational efficiency, as well as reducing workforce size. Industry 5.0: The Future of the Industrial Economy discusses the integration of product, process, machine, software, and industrial robots in realizing Industry 5.0. It covers the dual integration of human intelligence with machine intelligence and reviews the results of making use of Industrial Internet of Things (IIoT) and Artificial Intelligence (AI). The creation of a new category of robots named Collaborative Robots (Cobots) specifically designed to speed up the manufacturing process and profitability is explored. This book also explores how to reduce waste in product design through the manufacturing process and offers more personalized and customized products for customers. Manufacturing, design, industrial, and mechanical engineers, as well as practicing professionals, will find this book of interest. Management executives, CIOs, CEOs, IT professionals, and academics will also find something of value in this book that takes Industry 4.0 to Industry 5.0 and beyond.

Focusses on solving problems in the Structural Dynamics using ABAQUS Software. Helps analyze and model different types of structures with various dynamic and cyclic loads. Discusses simulation of irregular-shaped objects composed of several different materials with multipart boundary conditions. Includes application of various load effects to the developed structural models in ABAQUS Software. Covers broad array of applications such as bridges, offshores, dam, seismic resistant systems, and so forth.

Presents compendium of Remaining Useful Life (RUL) estimation methods and technologies used in predictive maintenance. Describes different approaches and prognosis methods for different assets. Includes comprehensive compilation of methods from model based, data driven to hybrid. Discusses benchmarking of RUL estimation methods according to accuracy an uncertainty depending on the target application, type of asset and forecast performance expected. Contains toolset of methods and way of deployment aimed at versatile audience.

This book gathers selected peer-reviewed papers from the 16th World Congress on Engineering Asset Management (WCEAM), held in Seville from 5-7 October 2022. This book covers a wide range of topics in Engineering Asset Management, including: Asset management and decision support system Industry 4.0 tools and its impact on asset management Monitoring, diagnostics and prognostics for smart maintenance Asset life cycle management Asset management in the industrial sector Human dimensions and asset management performance Infrastructure Asset management Asset condition, risk, resilience, and vulnerability assessments Asset operations and maintenance strategies Reliability and resilience engineering Applications of international and local guidelines and standards The breadth and depth of this state-of-the-art, comprehensive proceedings make it an excellent resource for asset management practitioners, researchers and academics, as well as undergraduate and postgraduate students.

Up to date with the fourth edition of PMI's Program Management Standard, PgMP (R) Practice Test Questions: 1000+ Practice Exam Questions for the PgMP (R) Examination contains more than 1,000 practice questions to help readers hone their knowledge and test their skills. It covers all five of the program management domains: Strategic Program Management, Program Management Life Cycle, Benefits Management, Stakeholder Management, and Governance. It also examines all of the sub domains of the lifecycle domain. With an easy-to-use format, this is an ideal resource for those preparing to take the PgMP (R) exam.

The fundamental motivation of this book is to contribute to the future advancement of Asset Management in the context of industrial plants and infrastructures. The book aims to foster a future perspective that takes advantage of value-based and intelligent asset management in order to make a step forward with respect to the evolution observed nowadays. Indeed, the current understanding of asset management is primarily supported by well-known standards. Nonetheless, asset management is still a young discipline and the knowledge developed by industry and academia is not set in stone yet. Furthermore, current trends in new organizational concepts and technologies lead to an evolutionary path in the field. Therefore, this book aims to discuss this evolutionary path, starting first of all from the consolidated theory, then moving forward to discuss: * The strategic understanding of value-based asset management in a company; * An operational definition of value, as a concept on the background of value-based asset management; * The identification of intelligent asset management, with the aim to frame a set of "tools" recommended to support the asset-related decision-making process over the asset lifecycle; * The emergence of new technologies such as cyber physical systems and digital twins, and the implications of this on asset management.

This book presents selected papers from the 1st International Conference on Industry 4.0 and Advanced Manufacturing held at the Indian Institute of Science, Bangalore and includes deliberations from stakeholders in manufacturing and Industry 4.0 on the nature, needs, challenges, opportunities, problems, and solutions in these transformational areas. Special emphasis is placed on exploring avenues for creating a vision of, and enablers for, sustainable, affordable, and human-centric Industry 4.0. The book showcases cutting edge practice, research, and educational innovation in this crucial and rapidly evolving area. This book will be useful to researchers in academia and industry, and will also be useful to policymakers involved in creating ecosystems for implementation of Industry 4.0.

• Documents experiences of site managers in developing countries to improve the research and practice and ultimately safety performance of the construction industry • Essential reading for construction managers, researchers and academics in the field of safety management, infrastructure delivery and project management

From the Foreword by Marshall Fisher, The Wharton School, University of Pennsylvania: As generation of academics and practitioners follows generation, it is worthwhile to compile long views of the research and practice in the past to shed light on research and practice going forward. This collection of peer-reviewed articles is intended to provide such a long view. This book contains a collection of chapters written by leading scholars/practitioners who have continued their efforts in developing and/or implementing innovative OR/MS tools for solving real world problems. In this book, the contributors share their perspectives about the past, present and future of OR/MS theoretical development, solution tools, modeling approaches, and applications. Specifically, this book collects chapters that offer insights about the following topics: * Survey articles taking a long view over the past two or more decades to arrive at the present state of the art while outlining ideas for future research. Surveys focus on use of a particular OR/MS approach, e.g., mathematical programming (LP, MILP, etc.) and solution methods for particular family of application, e.g., distribution system design, distribution planning system, health care. * Autobiographical or biographical accounts of how particular inventions (e.g., Structured Modeling) were made. These could include personal experiences in early development of OR/MS and an overview of what has happened since. * Development of OR/MS mathematical tools (e.g., stochastic programming, optimization theory). * Development of OR/MS in a particular industry sector such as global supply chain management. * Modeling systems for OR/MS and their development over time as well as speculation on future development (e.g., LINDO, LINGO, and What'sBest!) * New applications of OR/MS models (e.g., happiness) The target audience of this book is young researchers, graduate/advanced undergraduate students from OR/MS and related fields like computer science, engineering, and management as well as practitioners who want to understand how OR/MS modeling came about over the past few decades and what research topics or modeling approaches they could pursue in research or application.