This volume addresses the promise and challenges of employment, service roles and contexts in rehabilitation and mental health practice, developing readiness for employment, sustaining employment, and responding to the needs of people coping with a range of disabilities. The book is relevant to the education of human service professionals, and will enable practitioners to expand their awareness, understanding, and knowledge of the interface of rehabilitation and mental health.

Since questions about wireless phones andbrain cancer were first raised in early 1993, numerous scientificstudies and reviews have been conducted and published throughout the world with support from industry and government. The most comprehensive colloquium to date covering this science was co sponsored byt he International Committee on WirelessCommunication Health Research and Wireless Technology Research, LLC,a t the University "La Sapienza" ofR omein November 1995. Papers fromt hat colloquium with appropriate updates formt he foundation for the current volume. A follow up tothat colloquium isbeing planned fort he spring of 1999 byt he same group and thereport of that colloquium will bet he basis for Volume II ofthis series. As thescientific story about wireless phones and health effects continues to unfold over the next several years, it is important to evaluate thework ina context t hat isb eneficialt ot he enhancement ofpublic health. Two themesa re critical to an appropriate contextual understanding ofthis science.

Filarial nematodes constitute and important group of human pathogens in tropical regions of the world. Diseases associated with these worms are generally separated into two categories: filariasis, caused by infections of lymphatic dwelling parasites and onchocerciasis, or river blindness, caused by infections of Onchocerca volvulus. Other filariae specifically infect humans and it is likely that zoonotic filarial infections may alter the outcome of infections with human parasites. The chapters in this book will cover concepts that, in most instances, overlap all of these parasites as well as focus on new and emerging ideas. The Filaria, volume five of World Class Parasites, is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.

Like the first edition, the second edition of the Encyclopedia of Stress covers nearly every conceivable aspect and ramification of stress including a wide range of related topics such as neuroimmune interactions, cytokines, enzymatic disorders, effects on the cardiovascular system, immunity and inflammation, and physical illnesses. Over the last decade, scientists have presented convincing research showing that psychological stress increases vulnerability to disease. They now understand more clearly that stress may be the thread tying together illnesses that were previously believed to be unrelated. Bone loss, increased abdominal fat, and damaged memory cells in the hippocampus have been linked to elevated cortisol levels.
Building on the success of the first edition, this completely revised work surveys the vast amount of research generated in the past five years, resulting in a substantial revision with over 30% new material and over 100 new entries. Expanded sections include Animal Studies, Anxiety and Depression, Drugs, Depression, Disasters, and Psychological and Other Therapies.
Also available online via ScienceDirect (2007) - featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com.
* Timely update on the topic of Post-Traumatic Stress Disorder taking into account events such as terrorism and middle east wars
* Includes expanded coverage on anxiety and depression
* Incorporates entries on the advances in our knowledge ofimmunology, cytokines and cell mediated immunity involved in stress responses and autoimmune diseases such as multiple sclerosis and Type I diabetes

Environmental Chemistry is a relatively young science. Interest in this subject, however, is growing very rapidly and, although no agreement has been reached as yet about the exact content and limits of this interdisciplinary subject, there appears to be increasing interest in seeing environmental topics which are based on chemistry embodied in this subject. One of the first objectives of Environ mental Chemistry must be the study of the environment and of natural chemical processes which occur in the environment. A major purpose of this series on Environmental Chemistry, therefore, is to present a reasonably uniform view of various aspects of the chemistry of the environment and chemical reactions occurring in the environment. The industrial activities of man have given a new dimension to Environ mental Chemistry. We have now synthesized and described over five million chemical compounds and chemical industry produces about one hundred and fifty million tons of synthetic chemicals annually. We ship billions of tons of oil per year and through mining operations and other geophysical modifications, large quantities of inorganic and organic materials are released from their natural deposits. Cities and metropolitan areas of up to 15 million inhabitants produce large quantities of waste in relatively small and confined areas. Much of the chemical products and waste products of modern society are released into the environment either during production, storage, transport, use or ultimate disposal. These released materials participate in natural cycles and reactions and frequently lead to interference and disturbance of natural systems."

Environmental Chemistry is a relatively young science. Interest in this subject, however, is growing very rapidly and, although no agreement has been reached as yet about the exact content and limits of this interdisciplinary discipline, there appears to be increasing interest in seeing environmental topics which are based on chemistry embodied in this subject. One of the first objectives of Environmental Chemistry must be the study of the environment and of natural chemical processes which occur in the environment. A major purpose of this series on Environmental Chemistry, therefore, is to present a reasonably uniform view of various aspects of the chemistry of the environment and chemical reactions occurring in the environment. The industrial activities of man have given a new dimension to Environmental Chemistry. We have now synthesized and described over five million chemical compounds and chemical industry produces about hundred and fifty million tons of synthetic chemicals annually. We ship billions of tons of oil per year and through mining operations and other geophysical modifications, large quantities of inorganic and organic materials are released from their natural deposits. Cities and metropolitan areas of up to 15 million inhabitants produce large quantities of waste in relatively small and confined areas. Much of the chemical products and waste products of modern society are released into the environment either during production, storage, transport, use or ultimate disposal. These released materials participate in natural cycles and reactions and frequently lead to interference and disturbance of natural systems.

Excessive noise levels are generally acknowledged to have adverse effects on our environment. Studies indicate that excessive noise levels can cause fatigue in exposed individuals, lower efficiency and productivity, impaired speech communication, and hearing loss. Excessive noise is almost everywhere today - in the office, in schools, hospitals and other institutional facilities, in all classes of public buildings, and in our factories. INDUSTRIAL NOISE High noise levels in factories can make speech communication in the plant difficult and at times impossible. Foremen are often unable to hear warning shouts from co-workers. The problem of hearing loss due to excessive noise exposure is of particular concern to industry, and to the federal government. In the early 1970s, the United States Congress passed the Occupational Safety and Health Act (OSHA) which sets criteria for health hazards and established limits for noise exposure of industrial workers. The OSHA Noise Standard was amended in 1982 to require audiometric testing of all employees exposed to noise levels of 85 dB or above for eight hours. A NOISE IN COMMERCIAL AND INSTITUTIONAL BUILDINGS While noise levels in offices, stores, schools, and other commercial and institutional buildings seldom reach those encountered in many industrial environments, they often reach levels which are distracting to the occupants of such buildings. Impairment of speech communica tion among workers, or inversely the lack of speech privacy, are both deterrents to effiCiency and productivity and are detrimental to the occupants' comfort and sense of well-being."

Over the last few decades, there have been dramatic improvements in the understanding and research of environmental design. Numerous methods have been developed to enhance architectural design in order for it to be more energy efficient, sustainable and health enhancing.

This book presents several theories and techniques that can be used to improve how buildings are engineered and designed in order to utilize more sustainable construction methods while promoting the health of the building's occupants.

Contributions to the study of environmental design have come from a diversity of fields including applied mathematics, optimization, computer science, medical research, psychology, management science, architecture, and engineering. The techniques developed in these areas of research can be used to increase building performance, occupant satisfaction, productivity, and well being, and reducing the incidence of health conditions and chronic diseases related to the use of a designed space.

This book provides architectural practitioners, civil engineers as well as other interdisciplinary researchers with the techniques needed to design, implement, and test for sustainability and health promotion in new or existing structures.

Structure-Function Relationships of Human Pathogenic Viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions. The relation between structural features and the pathogenicity and oncogenicity of some of the most relevant human viral pathogens are demonstrated and the acquisition of defense mechanisms through virus-host interactions are presented. In contrast to textbooks, this volume combines timely research data to provide a holistic view of viral pathogenesis. Furthermore Structure-Function Relationships of Human Pathogenic Viruses illustrates in a single volume the fundamental processes involved in viral life cycles using up-to-date information from research laboratories around the world. Knowledge of these processes is crucial to develop rationales for the design of future drugs. The timeliness of the data and the comprehensive yet concise approach this book takes in order to present the world of viral pathogens should make it a frontrunner in higher education and R&D.

A good number of misconceptions are currently circulating on the effects of non-ionizing radiations on our health, which can lead to an oversimplification of the issue, to potentially dangerous assumptions or to misleading data analysis. Health effects may be exaggerated, or on the contrary underplayed. The authors of this work (doctors, engineers and researchers) have endeavored to supply validated and easily understandable scientific information on the electromagnetic fields and their biological and health effects. After a general review of the physics of the waves and a presentation of non-ionizing radiations, the authors review the main emission sources encountered in our daily environment. They summarize simply but as accurately as possible the current knowledge on their biological effects.
The safety limits recommended by international organizations are presented for the different frequency ranges. This book is intended for doctors, teachers, scientists, students, policy makers and anyone else interested in a deeper understanding of the health effects of electromagnetic fields. Intended to serve a broad readership, everyone will approach it according to their respective level of curiosity and knowledge. It is neither an exhaustive inventory of all the studies made to date, nor a survey text focusing only on some chosen studies. Nor is the objective to present all the sources of non-ionizing radiations. Interested readers will be given the opportunity to broaden their knowledge, also by consulting the selected bibliography presented by the authors at the end of each chapter.

This volume written by 25 experts from industry and research provides a thorough overview of commerically important and environmentally mobile organosilicon materials. It outlines the structure, properties and applications of the four most significant material classes, and summarizes their environmental entry, transport, fate and impact. Detection and analytical methods are discussed both in the context of environmental assay and ecotoxicity testing along with some of the challenges. Measurement/estimation techniques and data available for several eco-pertinent properties of selected organosilicon compounds are summarized and limitations of the estimation and expertimental methods discussed. The environmental laws/regulations/trends in the U.S., Europe and Japan are discussed, along with their relevance to organosilicon materials. The book concludes with a broad overview of the major markets and global silicone producers, reviewing the industry's stewardship initiatives, relevant HES (health, environmental and safety) organizations and global cooperation.

Recently, there has been interest by regulators, the public and the manufacturers of wireless devices in the issues relating to the safety of radio frequency (RF) energy. These issues require an understanding of the scientific underpinnings of both physics of RF energy and cellular biology. This book is designed to provide precisely such cross-functional expertise. The editors of this book intend to provide a reliable source for a sound scientific understanding of the issues and to stimulate future scientific advances in this area. Therefore, the audience for this book includes such diverse groups as scientists, governmental policy-makers and regulatory bodies, representatives of industry and the public at large.

A there it is! guide to insects of medical and public health concern, mainly in the tropics. Each chapter covers identification, life cycle and habits of the causative stage and its medical/public health significance.

Skin diseases caused by aquatic organisms are continually on the increase owing to the great number of people who now converge on the hydrosphere for holidays, sports and professional activities. Aquatic skin diseases are no longer only a seasonal affliction but can be observed at any period, thanks to the tourist boom promoting aquatic holidaymaking throughout the year. This book aims to contribute to the knowledge of some aquatic animals that have only developed a poisonous apparatus to protect themselves and adapt to their environment, as well as of the various clinical pictures induced by different pathogenic mechanisms. Besides the afflictions caused by biotoxins, skin reactions to microscopic organisms present in seawater, freshwater, swimming pools and aquariums are described, together with some non-biotic forms induced by direct contact with salt and freshwater. A better knowledge of the aquatic environment may help people to enjoy this enthralling habitat at lesser risk.

Leishmania parasites cause a diverse group of diseases endemic to many tropical and subtropical regions of the world. This volume seeks to bring together recent research on cell and molecular biology of Leishmania with chapters on the host response to infection, the current epidemiology of leishmaniasis, explanations of the many different species, vector control, and strategies for vaccine development and drug treatment. Leishmania, volume four of World Class Parasites, is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.

Carpal-tunnel and other entrapment syndromes are perhaps the most common work-related injuries currently reported. With this book, Vladimir Golovchinsky presents the first evidence of double-crush syndrome as a subgroup of these. To date the existence of double-crush syndrome has been a matter of debate. Dr. Golovchinsky presents a statistical analysis of substantial clinical material, which finds a cause-and-effect relationship between cervical or lumbar radiculopathy and peripheral entrapment in corresponding nerves, thus proving the existence of double-crush syndrome. This book will be invaluable to physicians performing EMG-NCV testing and to other healthcare professionals who encounter peripheral entrapment syndromes in their practices.

ACKNOWLEDGEMENTS PART 1 FISH CONSUMPTION AND METHYLMERCURY EXPOSURE IN THE AMAZON A. C. BARBOSA, A. M. GARCIA, J. R. DESOUZAI Mercurycontamination inhairofriverine 1-8 populations of Apiacas Reserve in the Brazilian Amazon E. D. BIDONE, Z. C. CASTILHOS, T. J. S. SANTOS, T. M. C. SOUZA and L. D. LACERDA I Fish contamination and human exposure to mercury in Tartarugalzinho River, Amapa State, Northern Amazon, Brazil. A screening approach 9-15 H. A. KEHRIG, O. MALM and H. AKAGI I Methylmercury in hair samples from different riverine groups, Amazon, Brazil 17-29 J. LEBEL, M. ROULET, D. MERGLER, M. LUCOTTE and F. LARRIBE I Fish diet and 31-44 mercury exposure in a riparian Amazonian population O. MALM. , J. R. D. GUIMARAES, M. B. CASTRO, W. R. BASTOS, J. P. VIANA, F. J. P. BRANCHES, E. G. SILVEIRA and W. C. PFEIFFER I Follow-up of mercury levels in fish, human hairand urine in the Madeira and Tapaj6s basins, Amazon, Brazil 45-51 PART 2 CHILD DEVELOPMENT AND LONG TERM EXPOSURE G. J. MYERS, P. W. DAVIDSON, C. COX, C. F. SHAMLAYE, O. CHOISY, E. CERNICHIARI, A. CHOI, J. SLOANE-REEVES, C. AXTELL, P. GAO and T. W. CLARKSON I The Seychelles child development study: Results and new directions through twenty-nine months 53-61 B. WHEATLEY, S. PARADIS, M. LASSONDE, M. -F. GIGUERE and S.

This volume focuses on the human exposures and medical effects studies in the SemipaiatinskJ Altai region of Siberia that were a consequence of the radioactive fallout from nuclear test explosions that took place at the Semipalatinsk Test Site of the former Soviet Union. It contains a detailed account of a NATO Advanced Research Workshop (ARW) devoted to the subject, and a selection of the papers presented. The title of the ARW was "Long-term Consequences of Nuclear Tests for the Environment and Population Health (SemipaiatinskJAltai Case Studies)." The estimated exposures to large numbers of people in the Altai lie in an important dose rate and dose domain. Hence the research reported herein provides new and unique information on the effects of radiation on humans. Also emphasized at the ARW were studies involving fallout from the Pacific Island tests of the U. S. A . . There have been over 2300 nuclear weapon test explosions to date. More than 500 took place in the atmosphere and outer space; the remainder were underground. The atmospheric tests comprise the largest source of anthropogenic radioactivity released into the earth's atmosphere to date. The vast majority, in number and yield, were carried out by the former Soviet Union (FSU) and the United States. Each superpower maintained two primary test sites, one continental primarily for small yield tests, and the other more remote for larger yield tests. For the U. S. A.

Although breast-feeding has long been associated with lowered infant morbid- ity and mortality from infectious disease, until relatively recently little was known regarding the individual components of human milk aside from their nutritive func- tions and the presence of secretory antibodies. Over the last 40 years, and especially over the last decade, evidence has been growing that human milk contains a large number of materials that are bioactive and that are not found in artificially formu- latedinfantdiets. Disparatelinesofresearcharecurrentlyproducingsurprisinglylong listsofnewlyrecognizedhumanmilkcomponents-antimicrobialsand immunomod- ulators, includinganti-inflammatoryagents, antioxidants, cytokines, andhormones- with biological activities that relate to pathogenesis, inflammation, development, metabolic regulation, and other functions. The sum of all of these biologically active milk components may account for the strong protection that human milk affords nursing infants. Strictly speaking, most components of human milk could be considered bioac- tive, since nutrients are bioactive by definition. A major emphasis of this book, how- ever, is on defining what is known about components of human milk that inhibit common pathogens of the infant, those that have hormonal and/or cytokine activity, those that have immunomodulatory and/or anti-inflammatory activity, xenobiotics, and nutrients that are uniquely essential to early development. The topic of bioactive substances in human milk was explored in depth at the th 8 International Conference of the International Society for Research on Human Milk and Lactation (ISRHML) held at Plymouth, Massachusetts, October 25-29, 1997. This book contains the proceedings of that conference.

Christiaan Eijkman received the Nobel prize for Medicine in 1929 for his discovery that beri-beri is a vitamin-deficiency disease. He had conducted his seminal research on the disease in the fonner Dutch East Indies between 1886 and 1898 at the location of. the present Eijkman Institute for Molecular Biology in Jakarta. In 1998, the first International Eijkman Symposium was held in The Hague, The Netherlands, to celebrate the fact that exactly 100 years earlier Christiaan Eijkman was inaugurated as full professor in Hygiene and Bacteriology at Utrecht University, The Netherlands. The Eijkman-Winkler Centre for Microbiology, Infectious Diseases and Inflammation is the direct descendant of Eijkman's department in Utrecht. vii Contributing Authors Bacbti Alisjabbana Department of Internal Medicine Padjadjaran University (UNP AD) Dr Hasan Sadikin General Hospital Bandung Indonesia Kevin Baird US Navy Medical Research Unit-2 J1. Percetakan Negara 29 Jakarta 15650 Indonesia Phone: +62-21-421-4457 Fax: +62-214244507 Jan P . B. van den Berg Nederland-Batam Foundation Stationsweg 56 6711 PT Ede The Netherlands Phone: +31-318610368 Fax: +31-318612476 Greet J. Boland Eijkman-Winkler Centre University Medical Centre Utrecht ix x Contributing Authors P. O. Box 85500 3584 CX Utrecht The Netherlands Phone: +31-302506536 Fax: +31-302541770 G J . Boland@azu. n1 Graham V. Brown Department of Medicine University of Melbourne Royal Melbourne Hospital Victoria Australia gvb@unimelb. edu. au Frank E. J. Coenjaerts Eijkman-Winkler Centre University Medical Centre Utrecht P. O. Box 85500 3584 CX Utrecht The Netherlands Phone: +31-302507637 Fax: +31-302541770 . EJ . Coenjaerts@lab. azu.

In recent years the field of contact dermatitis has increased greatly in importance in dermatology. The variety of exogenous, environmental ly caused dermatoses has undoubtedly expanded over the past few de cades with the increasing number of potentially toxic chemicals, the changes in lifestyle, and the greater life expectancy in industrialized societies. The value of international cooperation in this field has long been realized and acted upon by the International Contact Dermatitis Re search Group (ICDRG). By 1975 the international journal Contact Dermatitis had been founded under the editorship of C. D. Calnan. Thanks largely to the ICDRG and Contact Dermatitis, there were, by 1986, enough additional dermatologists and scientists with a special interest in this area to form the European Environmental and Contact Dermatitis Research Group (EECDRG). Within 2 years they had in stituted the European Society of Contact Dermatitis (ESCD) as an in ternational forum for researchers in the field. The EECDRG decided to hold a symposium in Heidelberg in May 1988, an initiative supported by the ICDRG, and on this occasion the new ESCD held its inaugural session. The Society already has over 200 members and most national contact dermatitis research groups in Europe are already represented; new members are of course welcome. Subgroups and working committees have been formed to address var ious topics including the standardization of patch testing, photoder matology, and bioengineering."

Japanese encephalitis and West Nile viruses are members of the Japanese encephalitis serological group of the genus Flavivirus and therefore closely related genetically and antigenically. They share a number of properties, including the use of birds as their major wildlife maintenance host and Culicine mosquitoes for transmission, and they are both associated with severe human disease, as well as fatal infections in horses.
The emergence of these two viruses, and their well-established propensity to colonise new areas, make it timely to re-examine their ecology, biology, molecular structure, replication and epidemiology, and these therefore provide the focus of this volume.

The probability for exposure to damaging radiation, toxic chemicals in the environment and adverse biological agents has increased exponentially today. The more frequent and faster travel that we experience today also escalates the risk of contraction and transmission of potentially deadly infections. This has created a very real and escalating risk for injuries and deaths. This is accentuated in the military and medical staff that is more frequently exposed to radiological, chemical, and biological agents in their normal working environment. Understanding the mechanisms whereby these toxic agents inflict damage to our bodies is essential to prepare us for these challenges. Much of the damage is inflicted through the generation of free radicals and non-radical oxidants which then act through oxidative mechanisms to injury the body. This volume will discuss the damage caused by these radiological, chemical, and biological environmental stressors, the mechanisms through which the damage can occur and the novel strategies that can be used to reduce the injury inflicted by these toxic compounds. Using basic and clinical research approaches, the contents of this book discuss new ideas for the development of bioactive products and environmental approaches to lessen or negate the biological damage inflicted by these noxious compounds.

Seasonal patterns have been found in a remarkable range of health conditions, including birth defects, respiratory infections and cardiovascular disease. Accurately estimating the size and timing of seasonal peaks in disease incidence is an aid to understanding the causes and possibly to developing interventions. With global warming increasing the intensity of seasonal weather patterns around the world, a review of the methods for estimating seasonal effects on health is timely.

This is the first book on statistical methods for seasonal data written for a health audience. It describes methods for a range of outcomes (including continuous, count and binomial data) and demonstrates appropriate techniques for summarising and modelling these data. It has a practical focus and uses interesting examples to motivate and illustrate the methods. The statistical procedures and example data sets are available in an R package called season ."