Safety-I is defined as the freedom from unacceptable harm. The purpose of traditional safety management is therefore to find ways to ensure this 'freedom'. But as socio-technical systems steadily have become larger and less tractable, this has become harder to do. Resilience engineering pointed out from the very beginning that resilient performance - an organisation's ability to function as required under expected and unexpected conditions alike - required more than the prevention of incidents and accidents. This developed into a new interpretation of safety (Safety-II) and consequently a new form of safety management. Safety-II changes safety management from protective safety and a focus on how things can go wrong, to productive safety and a focus on how things can and do go well. For Safety-II, the aim is not just the elimination of hazards and the prevention of failures and malfunctions but also how best to develop an organisation's potentials for resilient performance - the way it responds, monitors, learns, and anticipates. That requires models and methods that go beyond the Safety-I toolbox. This book introduces a comprehensive approach for the management of Safety-II, called the Resilience Assessment Grid (RAG). It explains the principles of the RAG and how it can be used to develop the resilience potentials. The RAG provides four sets of diagnostic and formative questions that can be tailored to any organisation. The questions are based on the principles of resilience engineering and backed by practical experience from several domains. Safety-II in Practice is for both the safety professional and academic reader. For the professional, it presents a workable method (RAG) for the management of Safety-II, with a proven track record. For academic and student readers, the book is a concise and practical presentation of resilience engineering.

Water is the driving force of all nature. This old quote from Leonardo da Vinci reminds us that without water life is simply not possible. As a consequence, water is probably the most important wealth for humanity. In spite of this, drinking water is still polluted by man-made toxicals gathered by waters in soils and the atmosphere. This book presents advanced methods to clean water and air. Chapters also focus on biofuels, greenhouse gases and genetically modified crops.

Human demand for energy has grown multi-folds in recent years. This is the result of rapidly increasing human population, which, in turn, has resulted in increased organic (petroleum) and inorganic pollution on the biosphere. Due to this, we are now facing a number of challenges to sustain life on earth. For example, the increased organic and inorganic pollution in our environment is leading to loss of biodiversity, degradation of environment and thus ultimately causing food insecurity. In this situation, it is imperative to keep updated ourselves with advances on the effects of pollutants, tolerance mechanisms and the potential of different plants and microbes in removing these pollutants from the environment. For this purpose, we invited a number of scientists worldwide to review the current scenario of the problems, current development, and future prospects of the challenges and their solutions in an International Conference on ''Plants and Environmental Pollution'' held in KAYSERI, TURKEY from 6-11 July 2009. The output of this conference has been summarized in the form of this book.

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

This book provides comprehensive research findings related to the environmental monitoring of radiation, levels of radioactive nuclides in various environments and dose estimation in residents after the Fukushima nuclear power plant accident caused severe environmental contamination with radioactive nuclides. At the beginning of the book, a technical review written by a leading researcher of nuclear reactor technology explains what happened at the power plant. The review is followed by a commentary from a former member of the International Commission on Radiological Protection, providing the reader with easily understandable information about the concept of radiation dosage. In the main part of the book, a series of scientific reports presents valuable data on the radiation surveys of the environment, environmental radioactivity, transfer models and parameters of radioactive nuclides and dose assessment among residents. These reports present a wide range of findings from the research carried out in a variety of activities by large governmental organizations as well as by small private groups and individuals. The reader thus will find a large collection of valuable and interesting data related to the environmental contamination by radioactive nuclides after the Fukushima accident. Although earlier reports on this issue have been made public, this book is the only publication to fully depict the actual situation by providing comprehensive data obtained by diverse organizations and individuals.

This book is a comprehensive guide to occupational factors of malignant diseases. It discusses potentially work-related malignancies, in the context of exposure assessment, specific clinical and pathological features of occupational cancer and biomarkers of exposure and disease. Epidemiological data about risk ratios of the cancer in question are reviewed for various occupations and with exposure to specific carcinogens, carcinogenic mechanisms, host susceptibility factors (genetic and other) and other environmental and life-style risk factors. Aspects such as surveillance of workers exposed to carcinogens and strategies for prevention of occupational cancer are also discussed. Occupational Cancers is aimed at oncologists, pathologists, residents in training, clinical researchers, clinicians in occupational health, epidemiologists, pulmonologists, lawyers and public health officials.

This standard work on contaminated site management covers the whole chain of steps involved in dealing with contaminated sites, from site investigation to remediation. An important focus throughout the book is on Risk Assessment. In addition, the book includes chapters on characterisation of natural and urban soils, bioavailability, natural attenuation, policy and stakeholder viewpoints and Brownfields. Typically, the book includes in-depth theories on soil contamination, along with offering possibilities for practical applications. More than sixty of the world's top experts from Europe, the USA, Australia and Canada have contributed to this book. The twenty-five chapters in this book offer relevant information for experienced scientists, students, consultants and regulators, as well as for 'new players' in contaminated site management

This comprehensive interdisciplinary synthesis focuses on the clinical and occupational intervention processes enabling workers to return to their jobs and sustain employment after injury or serious illness as well as ideas for improving the wide range of outcomes of entry and re-entry into the workplace. Information is accessible along key theoretical, research, and interventive lines, emphasizing a palette of evidence-informed approaches to return to work and stay at work planning and implementation, in the context of disability prevention. Condition-specific chapters detail best return to work and stay at work practices across diverse medical and psychological diagnoses, from musculoskeletal disorders to cancer, from TBI to PTSD. The resulting collection bridges the gap between research evidence and practice and gives readers necessary information from a range of critical perspectives. Among the featured topics: Understanding motivation to return to work: economy of gains and losses. Overcoming barriers to return to work: behavioral and cultural change. Program evaluation in return to work: an integrative framework. Working with stakeholders in return to work processes. Return to work after major limb loss. Improving work outcomes among cancer survivors.Return to work among women with fibromyalgia and chronic fatigue syndrome. The Handbook of Return to Work is an invaluable, unique and comprehensive resource for health, rehabilitation, clinical, counselling and industrial psychologists, rehabilitation specialists, occupational and physical therapists, family and primary care physicians, psychiatrists and physical medicine and rehabilitation as well as occupational medicine specialists, case and disability managers and human resource professionals. Academics and researchers across these fields will also find expert guidance and direction in these pages. It is an essential reading for all return to work and stay at work stakeholders.

This book is an overview of the hazards of firefighting, the health risks of exposure to combustion products that characterize firefighting, the science behind interpreting these risks for purposes of identifying diseases as work-related, and the legal and policy implications of adopting legislated "presumption" for purposes of compensation. The emphasis of the book will be on the risk of cancer, cardiovascular disease, traumatic hazards, and disabling psychosocial adjustment following major incidents. Several new studies have appeared recently, including the largest study of firefighters ever done, by the National Institute of Occupational Health and Safety (NIOSH). They evidence supports the conclusion that firefighters face significant occupational health risks in addition to the obviously severe safety hazards.

This book explains the chemistry of Organophosphorus compounds (OPs), their mechanism of toxicity and the history of OPs from their initial discovery to the development of new compounds such as Novichoks. It details the harmful effects to human health both as a result of acute and chronic OP exposure and the necessary clinical management of affected patients to reduce their toxic side effects. The book also explains the detrimental effect that OPs have had on the environment and the efforts being made to prevent this in the future. Finally, the book looks at the incidents where OPs have been used as chemical warfare agents. Basic and Clinical Toxicology of Organophosphorus Compounds aims to act as a comprehensive guide to all aspects of OPs and is a key resource for clinical toxicologists and related health professionals involved in the prevention, diagnosis and clinical management of OP patients, toxicologists and other scientists involved in research on OPs including regulatory issues and postgraduate students in Toxicology and related fields.

Homeostasis. The health of an organism is influenced by external and internal changes that may lead to the loss of homeostasis. Under healthy conditions organisms compensate these changes. If compensation fails disease ensues. Attention will be paid to lifestyle, environmental changes, genetic makeup and health system. It will be answered how lifestyle, environment, genetic makeup and social conditions help to maintain or upset the biological balance and lead to cancer. Tumor formation. To understand this process the transfer of intracellular and the pathways of extracellular information (signal transduction) will be reviewed briefly. Loss of cellular balance may lead to cell death (.e.g. apoptosis) or to rapid cell growth of cells leading to tumor formation. Metastasis. Animal tumor models serve to understand the spread of the primary tumor cells to distant locations of the organism. Different types of tumors and metastases will be reviewed.

This book discusses the latest findings towards ensuring people's safety, health, and welfare at work. It crosses different disciplines, such as work physiology, health informatics, workplace design, injury prevention, and occupational psychology. It presents new strategies for safety management, including accident prevention methods, such as performance testing and participatory ergonomics. The book, which is based on the AHFE 2016 International Conference on Safety Management and Human Factors, held on July 27-31, 2016, in Walt Disney World (R), Florida, USA, provides readers, including decision makers in government and public authorities, with a timely snapshot of the state of the art in the field of safety, health and welfare management. It also addresses agencies such as OSHA and NIOSH as well as other professionals dealing with occupational safety and health.

The book addresses the questions: Is Australia's rapidly growing human population and economy environmentally sustainable for its estuaries and coasts? What is needed to enable sustainable development? To answer these questions, this book reports detailed studies of 20 iconic Australian estuaries and bays by leading Australian estuarine scientists. That knowledge is synthesised in time and space across Australia to suggest what Australian estuaries will look like in 2050 and beyond based on socio-economic decisions that are made now, and changes that are needed to ensure sustainability. The book also has a Prologue by Mr Malcolm Fraser, former Prime Minister of Australia, which bridges environmental science, population policy and sustainability.

This book adopts a human ecology approach to present an overview of the biological responses to social, political, economic, cultural and environmental changes that affected human populations in the Yucatan Peninsula, Mexico, since the Classic Maya Period. Human bodies express social relations, and we can read these relations by analyzing biological tissues or systems, and by measuring certain phenotypical traits at the population level. Departing from this theoretical premise, the contributors to this volume analyze the interactions between ecosystems, sociocultural systems and human biology in a specific geographic region to show how changes in sociocultural and natural environment affect the health of a population over time. This edited volume brings together contributions from a range of different scientific disciplines - such as biological anthropology, bioarchaeology, human biology, nutrition, epidemiology, ecotoxicology, political economy, sociology and ecology - that analyze the interactions between culture, environment and health in different domains of human life, such as: The political ecology of food, nutrition and health Impacts of social and economic changes in children's diet and women's fertility Biological consequences of social vulnerability in urban areas Impacts of toxic contamination of natural resources on human health Ecological and sociocultural determinants of infectious diseases Culture, Environment and Health in the Yucatan Peninsula - A Human Ecology Perspective will be of interest to researchers from the social, health and life sciences dedicated to the study of the interactions between natural environments, human biology, health and social issues, especially in fields such as biological and sociocultural anthropology, health promotion and environmental health. It will also be a useful tool to health professionals and public agents responsible for designing and applying public health policies in contexts of social vulnerability.

Tropical diseases remain a major global concern, not only because they affect a huge part of the world population, but also because of the growing global movement of people associated with employment, tourism, and war. Recent advances in molecular biology, epitomized by the genomic revolution, have brought new promises of powerful scientific approaches to fight such diseases. The WHO's Advisory Committee on Health Research recognizes this fact in its recommendation on Genomics and World Health and stresses the need for concerted efforts by scientists in the developed world, where most of the recent advances in life sciences have occurred, and those in the tropical, mostly less developed countries, where such diseases are endemic. Tropical Diseases: From Molecule to Bedside exemplifies such an effort. It covers a wide range of topics that reflect perspectives of northern and southern hemispheres. Fittingly, it defines tropical diseases in a broader-than-usual manner. For example, the book discusses traditional tropical medicine topics of infectious diseases and nutritional deficiencies. These diseases are common in the tropics, although some are associated more with poverty than with tropical living conditions. It also deals with genetic diseases and genomic issues that are truly associated with living in the tropics, e.g. the thalassemias. The book begins with several papers describing the vast human genetic diversity of Southeast Asia and its relationship to several genetic disorders. These papers illustrate the future direction of genomic activities in relation to disease susceptibility and resistance. The next sections deal with malaria and four specific viral and bacterial diseasesof the tropics: hepatitis B and C, tuberculosis, and leprosy. These are then followed by a section on general bacterial infection. Two papers on nutrition complete the volume.
Proceedings of the second International Eijkman Symposium on Tropical Diseases: From Molecule to Bedside: In the Footsteps of Christiaan Eijkman, held September 2-6, 2001, in Bogor, Indonesia.

Environmental sustainability issues in a fragile, semi-arid region and its coastal area, which experience climate changes from extreme drought conditions to the effects of hurricanes over a period of weeks to years, provide specific challenges for the ecosystems and the populations existing within the region. The research presented focuses on the problems and some solutions specific to the South Texas-Mexico border region, on both sides of the Rio Grande, focusing on water and air pollution.

Humans are diurnal organisms whose biological clock and temporal organization depend on natural light/dark cycles. Changes in the photoperiod are a signal for seasonal acclimatization of physiological and immune systems as well as behavioral patterns. The invention of electrical light bulbs created more opportunities for work and leisure. However, exposure to artificial light at night (LAN) affects our biological clock, and suppresses pineal melatonin (MLT) production. Among its other properties, MLT is an antioncogenic agent, and therefore its suppression increases the risks of developing breast and prostate cancers (BC&PC). To the best of our knowledge, this book is the first to address the linkage between light pollution and BC&PC in humans. It explains several state-of-the-art theories, linking light pollution with BC&PC. It also illustrates research hypotheses about health effects of light pollution using the results of animal models and population-based studies.

Anja Schmidt's thesis is a unique and comprehensive evaluation of the impacts of tropospheric volcanic aerosol on the atmosphere, climate, air quality and human health. Using a state-of-the-art global microphysics model, the thesis describes and quantifies the impact of volcanic sulphur emissions on global aerosol, clouds and the radiative forcing of climate. The advanced model enables the first ever estimate of the impact of the emissions on aerosol microphysical properties such as particle number concentrations and sizes, and therefore a considerably improved ability to quantify the climate and air quality effects. There are several important discoveries in this thesis. Firstly, it is shown that continuously degassing volcanoes exert a major effect on global clouds and climate. Secondly, the impact of the 1783 Laki eruption in Iceland is re-examined to show that this long-lasting flood lava eruption would have had major effects on clouds and climate. Thirdly, by combining her research on volcanism, atmospheric science and epidemiology, she shows that a present-day Laki-like eruption would seriously affect European air quality and cause over 100000 premature deaths in the first year.

In recent decades radiobiologists' efforts have been directed at identifying the mechanisms of radiation effects; the general mechanisms have since been studied extensively. This book describes and analyzes radiation-induced adaptation as processes produced in cells, tissues, and populations. This viewpoint helps to understand the nature and factors of induced processes, to determine the characteristics of observed radiation effects and their limitations. The investigations presented here were founded on proper lab experiments, ecological studies of plant population growth near an operating nuclear power plant and a thorough epidemiological examination of human populations living in territories polluted fifty years ago, as well as on relevant published data. This research demonstrates the radiation-induced adaptation processes that continue even when the radiation itself is no longer at a critical background level. The investigations utilized the method of statistical modeling on the basis of distributions on the number of abnormalities. This method allows us to investigate the processes induced by low-dose factors when accompanied by Darwinian selection in different systems; the distribution parameters can then be used to study the characteristics of adaptation processes and system resistance. The consequences of background-level radiation continue to provoke debate, and the mathematical bases of the adaptation model are shown, while due consideration is paid to the components of adaptation: instability, selection, and proliferation. The book will be especially useful to specialists in radiation pollution, ecology, epidemiology, and radiology for studies of radiation-induced processes; the method presented here can also be adapted to investigate low-dose effects in other fields. In addition, the book presents a number of reviews in the fields of radiation biology, including pioneering investigations in Russia which were previously unavailable to Western scientists.

A close-to-ideal blend of suburb and city, speedy construction of towers of Babylon, the sparkling proportion of glass and steel buildings' facade at night showcase the wisdom of humans. They also witness the footsteps, sweats and tears of architects and engineers. Unfortunately, these signatures of human civilizations are swathed in towering figures of construction accidents. Fretting about these on sites, different countries adopt different measures on sites. This book firstly sketches the construction accidents on sites, followed by a review on safety measures in some of the developing countries such as Bermuda, Egypt, Kuwait and China; as well as developed countries, for example, the United States, France and Singapore. It also highlights the enormous compensation costs with the courts' experiences in the United Kingdom and Hong Kong.

The factors affecting water quality are many: The increasing buying power and health concerns of the world population contribute to the creation of new products whose production and disposal lead to the release of chemicals harmful to the environment; the ever-growing world population requires a steady food supply, which increases the pressure to use even more chemicals to control various crop pests; and due to climate change, head waters, rivers, and oceans are becoming increasingly warmer, acidic, and eutrophic as the result of carbod dioxide overload. Using specific examples, Water Quality and Resource Management will address the many challenges of providing clean water to the growing world population. It will also discuss the new technologies that are being developed, for example, to treat and reuse waste waters, and the innovative monitoring approaches that help scientists to assess water quality risks. Such risk assessments are urgently needed to help draft legislations and allow enforcement to ensure accessability to quality water for all. The structure of the book will be the following: Each chapter will provide information about a specific water environment and the challenges it faces. This will be followed by discussion of the pollution effects and actions taken to redress the situation. Finally, future trends will be discussed.

Here is a new book on methods and issues in clinical research. Its objectives can be summarized in three points. 1. Integrate medical and statistical components of clinical research. 2. Do justice to the operational and practical requirements of clinical research. 3. Give space to the ethical implications of methodological issues in clinical research. The book ends with a brief description of the drug development process and the phases of clinical development.

This Brief examines the impact of the Oxford Transport Strategy in central Oxford as a means of assessing the effect of reduced traffic congestion in the city centre on its sustainability. Air pollution (from vehicular traffic) has been monitored at three locations in central Oxford on the High Street, St Aldates and St Ebbes (background monitoring station). There is a further monitoring site situated in East Oxford, but this one is not considered to be central. Based on long-term monitoring at these monitoring stations, a deliberation of urban sustainability is presented. Implications are considered for long-term planning and green design in particular is part of the discussion. More specifically, urban greening strategies are presented as (soft engineering) approaches to controlling air pollution problems at this urban location. In the context of low carbon cities, green walls are assessed as they affect urban greening and energy conservation, as they enhance insulation on the exterior of solid wall buildings. Urban sustainability is best monitored using decades of data rather than just years. The Oxford Transport Strategy (OTS) was implemented in central Oxford, UK in 2001 and now a record of at least a decade of monitoring data is available for such a longer-term assessment. This work revisits the OTS from long after its implementation in the Oxford city centre and specifically examines the impact of reduced traffic congestion on sustainability. This includes address of traffic congestion, air pollution (from vehicular or traffic pollution) and the effects on the urban environment, including buildings. In parallel to this, the role of urban vegetation is considered as a sink for a variety of pollutants. Green walls, as part of urban greening, have implications for low carbon cities in the context of urban heat islands and global warming.

Many international experts collaborated in creating this groundbreaking work, a principal-coding system, and in developing reference films and imaging parameters for the International Classification of HRCT for Occupational and Environmental Respiratory Diseases. The book is an authoritative guide to the recognition of dust diseases of the lung, using radiological imaging techniques, with special emphasis on high-resolution computerized tomography (CT). The classification is a powerful, essential tool for recording patient data on CT in a globally standardized semiquantitative way. The system is also applicable to surveillance and screening for occupational and environmental respiratory diseases. The book is a valuable resource not only for radiologists but for all who work in occupational medicine and public health.

A Clinical Guide to Occupational and Environmental Lung Diseases delivers a concise compendium to the diagnosis and management of occupational and environmental lung diseases, incorporating evidence-based guidelines where available. Each chapter provides an updated review and a practical approach to different occupational and environmental lung diseases. With rapidly changing technology, new conditions and exposures will undoubtedly emerge. Clinicians need to remain vigilant about assessing the potential link between lung diseases and environmental exposures, and this book provides a practical guide to recognize, diagnose, and prevent occupational and environmental lung diseases. Written for practicing clinicians including internists, pulmonologists, and primary care providers, as well as industrial hygienists and environmental regulators, A Clinical Guide to Occupational and Environmental Lung Diseases is a timely and important new volume and an invaluable contribution to the literature.