This book is a comprehensive guide to occupational factors of malignant diseases. It discusses potentially work-related malignancies, in the context of exposure assessment, specific clinical and pathological features of occupational cancer and biomarkers of exposure and disease. Epidemiological data about risk ratios of the cancer in question are reviewed for various occupations and with exposure to specific carcinogens, carcinogenic mechanisms, host susceptibility factors (genetic and other) and other environmental and life-style risk factors. Aspects such as surveillance of workers exposed to carcinogens and strategies for prevention of occupational cancer are also discussed. Occupational Cancers is aimed at oncologists, pathologists, residents in training, clinical researchers, clinicians in occupational health, epidemiologists, pulmonologists, lawyers and public health officials.

This book serves as a comprehensive resource on toxicants that can be released from food packaging materials and household plastics. Chapters include sources and levels of chemical exposure, known and suspected health effects and the identification of data gaps with recommendations for further research. In addition, regulatory approaches and risk assessment challenges in the United States and Europe are discussed. Chapters cover both the more widely known chemicals that can migrate from food packaging (bisphenol A, perfluorinated chemicals), and household plastics (lead, phthalates, brominated flame retardants), as well as chemicals that are just entering use in food packaging (nanomaterials in polymer food packaging) and chemicals recently identified as migrating from food packaging to food stuffs (phthalates, benzophenones, antimony, methylnaphthalene and the alkylphenols nonylphenol and octylphenol). Chapters on phthalates and brominated flame retardants discuss challenges that arise with the use of replacement chemicals. The health effect sections of chapters have drawn on a wide variety of toxicological endpoints and recommend approaches to better assess toxicological risks in vulnerable human populations. Reflecting the global nature of our food supply and household consumer goods, contributions have been drawn from international experts. A wide range of scientists will find this book to be useful, including toxicologists, environmental health scientists, food scientists, and regulators.

The Handbook will cover all aspects of environmental analysis and will examine the emergence of many new classes of pollutants in recent years. It will provide information on an array of topics from instrumentation, analytical techniques, and sample preparations to statistical calculations, chemical structures, and equations. It will present the tools and techniques required to measure a wide range of toxic pollutants in our environment. It will be fully revised throughout, and will add four new chapters (Microbial Analysis, Chlorophyll, Chlorine, Chloramines and Chlorine Dioxide, and Derivatization Reactions in Environmental Analysis).

This book comprehensively describes the physiological changes and consequences that occur in humans during spaceflight. It specifically presents the adaptations of the cardiovascular and the respiratory system. Specific changes occurring after 10, 20 or more days in space are depicted. Furthermore, the book explains various effective countermeasures that are required upon return of the astronauts to Earth. The book is a must-have for all biomedical and clinical researchers in the field of cardiovascular biology and respiration, and a fascinating reading for all interested laymen, who wish to understand a bit more about spaceflight research and technology.

Including practical advice on how to conduct a stress audit and how to target stress 'hot spots' within an organization, Organizational Stress Management provides a fresh strategic model for the manager concerned with the negative effects stress can have both on company performance and the quality of life of individuals at work.

The Middle East and North Africa (MENA) is highly endemic for several neglected tropical diseases (NTDs), including viral, bacterial, protozoan and helminth infections. This new volume covers the most prevalent NTDs found in about 22 MENA countries emphasizing the disease burden, clinical manifestations and control approaches. Each individual chapter deals with one specific disease and is written by a group of experts on that topic.

This book explains the chemistry of Organophosphorus compounds (OPs), their mechanism of toxicity and the history of OPs from their initial discovery to the development of new compounds such as Novichoks. It details the harmful effects to human health both as a result of acute and chronic OP exposure and the necessary clinical management of affected patients to reduce their toxic side effects. The book also explains the detrimental effect that OPs have had on the environment and the efforts being made to prevent this in the future. Finally, the book looks at the incidents where OPs have been used as chemical warfare agents. Basic and Clinical Toxicology of Organophosphorus Compounds aims to act as a comprehensive guide to all aspects of OPs and is a key resource for clinical toxicologists and related health professionals involved in the prevention, diagnosis and clinical management of OP patients, toxicologists and other scientists involved in research on OPs including regulatory issues and postgraduate students in Toxicology and related fields.

This book is an overview of the hazards of firefighting, the health risks of exposure to combustion products that characterize firefighting, the science behind interpreting these risks for purposes of identifying diseases as work-related, and the legal and policy implications of adopting legislated "presumption" for purposes of compensation. The emphasis of the book will be on the risk of cancer, cardiovascular disease, traumatic hazards, and disabling psychosocial adjustment following major incidents. Several new studies have appeared recently, including the largest study of firefighters ever done, by the National Institute of Occupational Health and Safety (NIOSH). They evidence supports the conclusion that firefighters face significant occupational health risks in addition to the obviously severe safety hazards.

Human demand for energy has grown multi-folds in recent years. This is the result of rapidly increasing human population, which, in turn, has resulted in increased organic (petroleum) and inorganic pollution on the biosphere. Due to this, we are now facing a number of challenges to sustain life on earth. For example, the increased organic and inorganic pollution in our environment is leading to loss of biodiversity, degradation of environment and thus ultimately causing food insecurity. In this situation, it is imperative to keep updated ourselves with advances on the effects of pollutants, tolerance mechanisms and the potential of different plants and microbes in removing these pollutants from the environment. For this purpose, we invited a number of scientists worldwide to review the current scenario of the problems, current development, and future prospects of the challenges and their solutions in an International Conference on ''Plants and Environmental Pollution'' held in KAYSERI, TURKEY from 6-11 July 2009. The output of this conference has been summarized in the form of this book.

This book intensively examines the efficacy of plant-derived products that have been used for over a thousand years by practitioners of so-called Traditional Chinese Medicine in the light of recent chemotherapeuticals. The chapters were written by renowned Chinese medical researchers and are supplemented by results obtained in German antiparasitic research projects. Parasites and emerging diseases are a major threat of our time, which is characterized by an enormous increase in the size of the human population and by an unbelievably rapid globalization that has led to the daily transport of millions of humans and containers with goods from one end of the earth to the other. Furthermore the slow but constant global warming offers new opportunities for many agents of diseases to become established in new areas. Therefore it is essential that we develop precautions in order to avoid epidemics or even pandemics in overcrowded megacities or at the large-scale farm animal confinements that are needed to secure a steady flow of food in the crowded regions of the world. Of course intensive research in the field of chemotherapy since 1900 has produced unbelievable breakthroughs in therapies for formerly untreatable and thus deadly diseases. However, a large number of untreatable diseases remain, as well as a constantly growing number of agents of disease that have developed resistances to standard chemical compounds. As such, it is not only worthwhile but also vital to consider the enormous amounts of information that have been obtained by human "high cultures" in the past. Examples from the past (like quinine) or present (like artemisinin, a modern antimalarial drug) show that plant extracts may hold tremendous potential in the fight against parasites and/or against vector-transmitted agents of diseases.

This book discusses the latest findings towards ensuring people's safety, health, and welfare at work. It crosses different disciplines, such as work physiology, health informatics, workplace design, injury prevention, and occupational psychology. It presents new strategies for safety management, including accident prevention methods, such as performance testing and participatory ergonomics. The book, which is based on the AHFE 2016 International Conference on Safety Management and Human Factors, held on July 27-31, 2016, in Walt Disney World (R), Florida, USA, provides readers, including decision makers in government and public authorities, with a timely snapshot of the state of the art in the field of safety, health and welfare management. It also addresses agencies such as OSHA and NIOSH as well as other professionals dealing with occupational safety and health.

Safety-I is defined as the freedom from unacceptable harm. The purpose of traditional safety management is therefore to find ways to ensure this 'freedom'. But as socio-technical systems steadily have become larger and less tractable, this has become harder to do. Resilience engineering pointed out from the very beginning that resilient performance - an organisation's ability to function as required under expected and unexpected conditions alike - required more than the prevention of incidents and accidents. This developed into a new interpretation of safety (Safety-II) and consequently a new form of safety management. Safety-II changes safety management from protective safety and a focus on how things can go wrong, to productive safety and a focus on how things can and do go well. For Safety-II, the aim is not just the elimination of hazards and the prevention of failures and malfunctions but also how best to develop an organisation's potentials for resilient performance - the way it responds, monitors, learns, and anticipates. That requires models and methods that go beyond the Safety-I toolbox. This book introduces a comprehensive approach for the management of Safety-II, called the Resilience Assessment Grid (RAG). It explains the principles of the RAG and how it can be used to develop the resilience potentials. The RAG provides four sets of diagnostic and formative questions that can be tailored to any organisation. The questions are based on the principles of resilience engineering and backed by practical experience from several domains. Safety-II in Practice is for both the safety professional and academic reader. For the professional, it presents a workable method (RAG) for the management of Safety-II, with a proven track record. For academic and student readers, the book is a concise and practical presentation of resilience engineering.

This book provides comprehensive research findings related to the environmental monitoring of radiation, levels of radioactive nuclides in various environments and dose estimation in residents after the Fukushima nuclear power plant accident caused severe environmental contamination with radioactive nuclides. At the beginning of the book, a technical review written by a leading researcher of nuclear reactor technology explains what happened at the power plant. The review is followed by a commentary from a former member of the International Commission on Radiological Protection, providing the reader with easily understandable information about the concept of radiation dosage. In the main part of the book, a series of scientific reports presents valuable data on the radiation surveys of the environment, environmental radioactivity, transfer models and parameters of radioactive nuclides and dose assessment among residents. These reports present a wide range of findings from the research carried out in a variety of activities by large governmental organizations as well as by small private groups and individuals. The reader thus will find a large collection of valuable and interesting data related to the environmental contamination by radioactive nuclides after the Fukushima accident. Although earlier reports on this issue have been made public, this book is the only publication to fully depict the actual situation by providing comprehensive data obtained by diverse organizations and individuals.

The book addresses the questions: Is Australia's rapidly growing human population and economy environmentally sustainable for its estuaries and coasts? What is needed to enable sustainable development? To answer these questions, this book reports detailed studies of 20 iconic Australian estuaries and bays by leading Australian estuarine scientists. That knowledge is synthesised in time and space across Australia to suggest what Australian estuaries will look like in 2050 and beyond based on socio-economic decisions that are made now, and changes that are needed to ensure sustainability. The book also has a Prologue by Mr Malcolm Fraser, former Prime Minister of Australia, which bridges environmental science, population policy and sustainability.

This book adopts a human ecology approach to present an overview of the biological responses to social, political, economic, cultural and environmental changes that affected human populations in the Yucatan Peninsula, Mexico, since the Classic Maya Period. Human bodies express social relations, and we can read these relations by analyzing biological tissues or systems, and by measuring certain phenotypical traits at the population level. Departing from this theoretical premise, the contributors to this volume analyze the interactions between ecosystems, sociocultural systems and human biology in a specific geographic region to show how changes in sociocultural and natural environment affect the health of a population over time. This edited volume brings together contributions from a range of different scientific disciplines - such as biological anthropology, bioarchaeology, human biology, nutrition, epidemiology, ecotoxicology, political economy, sociology and ecology - that analyze the interactions between culture, environment and health in different domains of human life, such as: The political ecology of food, nutrition and health Impacts of social and economic changes in children's diet and women's fertility Biological consequences of social vulnerability in urban areas Impacts of toxic contamination of natural resources on human health Ecological and sociocultural determinants of infectious diseases Culture, Environment and Health in the Yucatan Peninsula - A Human Ecology Perspective will be of interest to researchers from the social, health and life sciences dedicated to the study of the interactions between natural environments, human biology, health and social issues, especially in fields such as biological and sociocultural anthropology, health promotion and environmental health. It will also be a useful tool to health professionals and public agents responsible for designing and applying public health policies in contexts of social vulnerability.

Tropical diseases remain a major global concern, not only because they affect a huge part of the world population, but also because of the growing global movement of people associated with employment, tourism, and war. Recent advances in molecular biology, epitomized by the genomic revolution, have brought new promises of powerful scientific approaches to fight such diseases. The WHO's Advisory Committee on Health Research recognizes this fact in its recommendation on Genomics and World Health and stresses the need for concerted efforts by scientists in the developed world, where most of the recent advances in life sciences have occurred, and those in the tropical, mostly less developed countries, where such diseases are endemic. Tropical Diseases: From Molecule to Bedside exemplifies such an effort. It covers a wide range of topics that reflect perspectives of northern and southern hemispheres. Fittingly, it defines tropical diseases in a broader-than-usual manner. For example, the book discusses traditional tropical medicine topics of infectious diseases and nutritional deficiencies. These diseases are common in the tropics, although some are associated more with poverty than with tropical living conditions. It also deals with genetic diseases and genomic issues that are truly associated with living in the tropics, e.g. the thalassemias. The book begins with several papers describing the vast human genetic diversity of Southeast Asia and its relationship to several genetic disorders. These papers illustrate the future direction of genomic activities in relation to disease susceptibility and resistance. The next sections deal with malaria and four specific viral and bacterial diseasesof the tropics: hepatitis B and C, tuberculosis, and leprosy. These are then followed by a section on general bacterial infection. Two papers on nutrition complete the volume.
Proceedings of the second International Eijkman Symposium on Tropical Diseases: From Molecule to Bedside: In the Footsteps of Christiaan Eijkman, held September 2-6, 2001, in Bogor, Indonesia.

Environmental sustainability issues in a fragile, semi-arid region and its coastal area, which experience climate changes from extreme drought conditions to the effects of hurricanes over a period of weeks to years, provide specific challenges for the ecosystems and the populations existing within the region. The research presented focuses on the problems and some solutions specific to the South Texas-Mexico border region, on both sides of the Rio Grande, focusing on water and air pollution.

Humans are diurnal organisms whose biological clock and temporal organization depend on natural light/dark cycles. Changes in the photoperiod are a signal for seasonal acclimatization of physiological and immune systems as well as behavioral patterns. The invention of electrical light bulbs created more opportunities for work and leisure. However, exposure to artificial light at night (LAN) affects our biological clock, and suppresses pineal melatonin (MLT) production. Among its other properties, MLT is an antioncogenic agent, and therefore its suppression increases the risks of developing breast and prostate cancers (BC&PC). To the best of our knowledge, this book is the first to address the linkage between light pollution and BC&PC in humans. It explains several state-of-the-art theories, linking light pollution with BC&PC. It also illustrates research hypotheses about health effects of light pollution using the results of animal models and population-based studies.

Anja Schmidt's thesis is a unique and comprehensive evaluation of the impacts of tropospheric volcanic aerosol on the atmosphere, climate, air quality and human health. Using a state-of-the-art global microphysics model, the thesis describes and quantifies the impact of volcanic sulphur emissions on global aerosol, clouds and the radiative forcing of climate. The advanced model enables the first ever estimate of the impact of the emissions on aerosol microphysical properties such as particle number concentrations and sizes, and therefore a considerably improved ability to quantify the climate and air quality effects. There are several important discoveries in this thesis. Firstly, it is shown that continuously degassing volcanoes exert a major effect on global clouds and climate. Secondly, the impact of the 1783 Laki eruption in Iceland is re-examined to show that this long-lasting flood lava eruption would have had major effects on clouds and climate. Thirdly, by combining her research on volcanism, atmospheric science and epidemiology, she shows that a present-day Laki-like eruption would seriously affect European air quality and cause over 100000 premature deaths in the first year.

In recent decades radiobiologists' efforts have been directed at identifying the mechanisms of radiation effects; the general mechanisms have since been studied extensively. This book describes and analyzes radiation-induced adaptation as processes produced in cells, tissues, and populations. This viewpoint helps to understand the nature and factors of induced processes, to determine the characteristics of observed radiation effects and their limitations. The investigations presented here were founded on proper lab experiments, ecological studies of plant population growth near an operating nuclear power plant and a thorough epidemiological examination of human populations living in territories polluted fifty years ago, as well as on relevant published data. This research demonstrates the radiation-induced adaptation processes that continue even when the radiation itself is no longer at a critical background level. The investigations utilized the method of statistical modeling on the basis of distributions on the number of abnormalities. This method allows us to investigate the processes induced by low-dose factors when accompanied by Darwinian selection in different systems; the distribution parameters can then be used to study the characteristics of adaptation processes and system resistance. The consequences of background-level radiation continue to provoke debate, and the mathematical bases of the adaptation model are shown, while due consideration is paid to the components of adaptation: instability, selection, and proliferation. The book will be especially useful to specialists in radiation pollution, ecology, epidemiology, and radiology for studies of radiation-induced processes; the method presented here can also be adapted to investigate low-dose effects in other fields. In addition, the book presents a number of reviews in the fields of radiation biology, including pioneering investigations in Russia which were previously unavailable to Western scientists.

A close-to-ideal blend of suburb and city, speedy construction of towers of Babylon, the sparkling proportion of glass and steel buildings' facade at night showcase the wisdom of humans. They also witness the footsteps, sweats and tears of architects and engineers. Unfortunately, these signatures of human civilizations are swathed in towering figures of construction accidents. Fretting about these on sites, different countries adopt different measures on sites. This book firstly sketches the construction accidents on sites, followed by a review on safety measures in some of the developing countries such as Bermuda, Egypt, Kuwait and China; as well as developed countries, for example, the United States, France and Singapore. It also highlights the enormous compensation costs with the courts' experiences in the United Kingdom and Hong Kong.

This book includes a collection of chapters illustrating the application of geochemical methods to investigate the interactions between geological materials and fluids with humans. Examples include the incorporation and human health effects of inhaling lithogenic materials, the reactivity of biological fluids with geological materials, and the impact on nascent biomineral formation. Biomineralization is investigated in terms of mineralogy, morphology, bone chemistry, and pathological significance with a focus on the health impacts of "foreign" geological/environmental trace element incorporation. One of the contribution is devoted to particulate matter, the presence of metals and metalloids in the environment, and the possibility of using human hair as a biomarker between environmental/geological exposure and human bioincorporation. Other chapters focus on the last advances on the analytical methods and instrumentational approaches to investigating the chemistry of biological fluids and tissues.

The factors affecting water quality are many: The increasing buying power and health concerns of the world population contribute to the creation of new products whose production and disposal lead to the release of chemicals harmful to the environment; the ever-growing world population requires a steady food supply, which increases the pressure to use even more chemicals to control various crop pests; and due to climate change, head waters, rivers, and oceans are becoming increasingly warmer, acidic, and eutrophic as the result of carbod dioxide overload. Using specific examples, Water Quality and Resource Management will address the many challenges of providing clean water to the growing world population. It will also discuss the new technologies that are being developed, for example, to treat and reuse waste waters, and the innovative monitoring approaches that help scientists to assess water quality risks. Such risk assessments are urgently needed to help draft legislations and allow enforcement to ensure accessability to quality water for all. The structure of the book will be the following: Each chapter will provide information about a specific water environment and the challenges it faces. This will be followed by discussion of the pollution effects and actions taken to redress the situation. Finally, future trends will be discussed.

In the search for snakebite antidotes, the ecology and evolution of venomous snakes is of critical importance. This book presents a multidisciplinary approach to venomous snake research, as well as focusing on the medical aspects of snake venoms and the effects of snakebites. Herpetology is a growing subject, and this book will appeal to the ever-increasing number of amateur snake enthusiasts. The book will also be an essential reference work for researchers involved in any aspect of venomous snake research, as well as those interested in the broader fields of ecology and evolution.