Presented here is an account of industrial and general air pollution problems in view of air quality management, community and industrial health aspects, emission inventorying, emission and air quality measurement techniques, dispersion phenomena and control technologies. Moreover, several case studies from automotive and manufacturing processes as well as some country reports are presented. Finally, the global warming problem (greenhouse effect), atmospheric carbon dioxide build-up and radiation hazards involved in the atmosphere are discussed.

This volume throws light on the Sick Building Syndrome in Libraries and other public buildings, and the extent to which it is influenced by the internal environment of libraries. One of the signs of this disease is that the person suffers from a set of symptoms closely related to his/her presence in the building, without the identification of any clear causes, and his/her relief of these symptoms when he/she are out of the building. Hence, the book sheds on the extent to which the interior environment impacts upon the health of the people, and the extent to which this is reflected in their performance. The book can be used for teaching, research, and professional reference. It concludes with the recommendation that is essential to observe environmental dimensions when designing library and public buildings, taking into consideration the expected impact of SBS in library and public buildings on people. The significance of the book derives from the fact that it is the first of its kind to examine the issue of the interior environment and SBS of library and public building worldwide.

Key Features Comprehensive coverage of all aspects of work-related asthma, including historical aspects, epidemiology and risk factors, mechanisms and genetics, other types of work-related asthma conditions and variants, hypersensitivity pneumonitis, occupational urticaria and dermatitis Assessment of the worker and workplace along with management of the worker, prevention and medicolegal aspects Of interest not only to pulmonologists, but also for industrial hygienists, researchers, lawyers and other health professionals in the field of work-related conditions Detailed information about specific agents, including a variety of high- and low-molecular weight agents

Filarial nematodes constitute and important group of human pathogens in tropical regions of the world. Diseases associated with these worms are generally separated into two categories: filariasis, caused by infections of lymphatic dwelling parasites and onchocerciasis, or river blindness, caused by infections of Onchocerca volvulus. Other filariae specifically infect humans and it is likely that zoonotic filarial infections may alter the outcome of infections with human parasites. The chapters in this book will cover concepts that, in most instances, overlap all of these parasites as well as focus on new and emerging ideas. The Filaria, volume five of World Class Parasites, is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.

An important purpose of The Handbook of Environmental Chemistry is to aid the understanding of distribution and chemical reaction processes which occur in the environment. It is designed to serve as an important source for environmental scientists and decision-makers in industry, governmental and regulatory bodies. "Volume 3, Part E" of this series is dedicated to organometallic compounds, aluminium and to chemicals used in the rubber industry.

Over the last few decades, there have been dramatic improvements in the understanding and research of environmental design. Numerous methods have been developed to enhance architectural design in order for it to be more energy efficient, sustainable and health enhancing.

This book presents several theories and techniques that can be used to improve how buildings are engineered and designed in order to utilize more sustainable construction methods while promoting the health of the building's occupants.

Contributions to the study of environmental design have come from a diversity of fields including applied mathematics, optimization, computer science, medical research, psychology, management science, architecture, and engineering. The techniques developed in these areas of research can be used to increase building performance, occupant satisfaction, productivity, and well being, and reducing the incidence of health conditions and chronic diseases related to the use of a designed space.

This book provides architectural practitioners, civil engineers as well as other interdisciplinary researchers with the techniques needed to design, implement, and test for sustainability and health promotion in new or existing structures.

This volume written by 25 experts from industry and research provides a thorough overview of commerically important and environmentally mobile organosilicon materials. It outlines the structure, properties and applications of the four most significant material classes, and summarizes their environmental entry, transport, fate and impact. Detection and analytical methods are discussed both in the context of environmental assay and ecotoxicity testing along with some of the challenges. Measurement/estimation techniques and data available for several eco-pertinent properties of selected organosilicon compounds are summarized and limitations of the estimation and expertimental methods discussed. The environmental laws/regulations/trends in the U.S., Europe and Japan are discussed, along with their relevance to organosilicon materials. The book concludes with a broad overview of the major markets and global silicone producers, reviewing the industry's stewardship initiatives, relevant HES (health, environmental and safety) organizations and global cooperation.

Structure-Function Relationships of Human Pathogenic Viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions. The relation between structural features and the pathogenicity and oncogenicity of some of the most relevant human viral pathogens are demonstrated and the acquisition of defense mechanisms through virus-host interactions are presented. In contrast to textbooks, this volume combines timely research data to provide a holistic view of viral pathogenesis. Furthermore Structure-Function Relationships of Human Pathogenic Viruses illustrates in a single volume the fundamental processes involved in viral life cycles using up-to-date information from research laboratories around the world. Knowledge of these processes is crucial to develop rationales for the design of future drugs. The timeliness of the data and the comprehensive yet concise approach this book takes in order to present the world of viral pathogens should make it a frontrunner in higher education and R&D.

Recently, there has been interest by regulators, the public and the manufacturers of wireless devices in the issues relating to the safety of radio frequency (RF) energy. These issues require an understanding of the scientific underpinnings of both physics of RF energy and cellular biology. This book is designed to provide precisely such cross-functional expertise. The editors of this book intend to provide a reliable source for a sound scientific understanding of the issues and to stimulate future scientific advances in this area. Therefore, the audience for this book includes such diverse groups as scientists, governmental policy-makers and regulatory bodies, representatives of industry and the public at large.

A there it is! guide to insects of medical and public health concern, mainly in the tropics. Each chapter covers identification, life cycle and habits of the causative stage and its medical/public health significance.

Leishmania parasites cause a diverse group of diseases endemic to many tropical and subtropical regions of the world. This volume seeks to bring together recent research on cell and molecular biology of Leishmania with chapters on the host response to infection, the current epidemiology of leishmaniasis, explanations of the many different species, vector control, and strategies for vaccine development and drug treatment. Leishmania, volume four of World Class Parasites, is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.

ACKNOWLEDGEMENTS PART 1 FISH CONSUMPTION AND METHYLMERCURY EXPOSURE IN THE AMAZON A. C. BARBOSA, A. M. GARCIA, J. R. DESOUZAI Mercurycontamination inhairofriverine 1-8 populations of Apiacas Reserve in the Brazilian Amazon E. D. BIDONE, Z. C. CASTILHOS, T. J. S. SANTOS, T. M. C. SOUZA and L. D. LACERDA I Fish contamination and human exposure to mercury in Tartarugalzinho River, Amapa State, Northern Amazon, Brazil. A screening approach 9-15 H. A. KEHRIG, O. MALM and H. AKAGI I Methylmercury in hair samples from different riverine groups, Amazon, Brazil 17-29 J. LEBEL, M. ROULET, D. MERGLER, M. LUCOTTE and F. LARRIBE I Fish diet and 31-44 mercury exposure in a riparian Amazonian population O. MALM. , J. R. D. GUIMARAES, M. B. CASTRO, W. R. BASTOS, J. P. VIANA, F. J. P. BRANCHES, E. G. SILVEIRA and W. C. PFEIFFER I Follow-up of mercury levels in fish, human hairand urine in the Madeira and Tapaj6s basins, Amazon, Brazil 45-51 PART 2 CHILD DEVELOPMENT AND LONG TERM EXPOSURE G. J. MYERS, P. W. DAVIDSON, C. COX, C. F. SHAMLAYE, O. CHOISY, E. CERNICHIARI, A. CHOI, J. SLOANE-REEVES, C. AXTELL, P. GAO and T. W. CLARKSON I The Seychelles child development study: Results and new directions through twenty-nine months 53-61 B. WHEATLEY, S. PARADIS, M. LASSONDE, M. -F. GIGUERE and S.

Like the first edition, the second edition of the Encyclopedia of Stress covers nearly every conceivable aspect and ramification of stress including a wide range of related topics such as neuroimmune interactions, cytokines, enzymatic disorders, effects on the cardiovascular system, immunity and inflammation, and physical illnesses. Over the last decade, scientists have presented convincing research showing that psychological stress increases vulnerability to disease. They now understand more clearly that stress may be the thread tying together illnesses that were previously believed to be unrelated. Bone loss, increased abdominal fat, and damaged memory cells in the hippocampus have been linked to elevated cortisol levels.
Building on the success of the first edition, this completely revised work surveys the vast amount of research generated in the past five years, resulting in a substantial revision with over 30% new material and over 100 new entries. Expanded sections include Animal Studies, Anxiety and Depression, Drugs, Depression, Disasters, and Psychological and Other Therapies.
Also available online via ScienceDirect (2007) - featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com.
* Timely update on the topic of Post-Traumatic Stress Disorder taking into account events such as terrorism and middle east wars
* Includes expanded coverage on anxiety and depression
* Incorporates entries on the advances in our knowledge ofimmunology, cytokines and cell mediated immunity involved in stress responses and autoimmune diseases such as multiple sclerosis and Type I diabetes

Christiaan Eijkman received the Nobel prize for Medicine in 1929 for his discovery that beri-beri is a vitamin-deficiency disease. He had conducted his seminal research on the disease in the fonner Dutch East Indies between 1886 and 1898 at the location of. the present Eijkman Institute for Molecular Biology in Jakarta. In 1998, the first International Eijkman Symposium was held in The Hague, The Netherlands, to celebrate the fact that exactly 100 years earlier Christiaan Eijkman was inaugurated as full professor in Hygiene and Bacteriology at Utrecht University, The Netherlands. The Eijkman-Winkler Centre for Microbiology, Infectious Diseases and Inflammation is the direct descendant of Eijkman's department in Utrecht. vii Contributing Authors Bacbti Alisjabbana Department of Internal Medicine Padjadjaran University (UNP AD) Dr Hasan Sadikin General Hospital Bandung Indonesia Kevin Baird US Navy Medical Research Unit-2 J1. Percetakan Negara 29 Jakarta 15650 Indonesia Phone: +62-21-421-4457 Fax: +62-214244507 Jan P . B. van den Berg Nederland-Batam Foundation Stationsweg 56 6711 PT Ede The Netherlands Phone: +31-318610368 Fax: +31-318612476 Greet J. Boland Eijkman-Winkler Centre University Medical Centre Utrecht ix x Contributing Authors P. O. Box 85500 3584 CX Utrecht The Netherlands Phone: +31-302506536 Fax: +31-302541770 G J . Boland@azu. n1 Graham V. Brown Department of Medicine University of Melbourne Royal Melbourne Hospital Victoria Australia gvb@unimelb. edu. au Frank E. J. Coenjaerts Eijkman-Winkler Centre University Medical Centre Utrecht P. O. Box 85500 3584 CX Utrecht The Netherlands Phone: +31-302507637 Fax: +31-302541770 . EJ . Coenjaerts@lab. azu.

Carpal-tunnel and other entrapment syndromes are perhaps the most common work-related injuries currently reported. With this book, Vladimir Golovchinsky presents the first evidence of double-crush syndrome as a subgroup of these. To date the existence of double-crush syndrome has been a matter of debate. Dr. Golovchinsky presents a statistical analysis of substantial clinical material, which finds a cause-and-effect relationship between cervical or lumbar radiculopathy and peripheral entrapment in corresponding nerves, thus proving the existence of double-crush syndrome. This book will be invaluable to physicians performing EMG-NCV testing and to other healthcare professionals who encounter peripheral entrapment syndromes in their practices.

Japanese encephalitis and West Nile viruses are members of the Japanese encephalitis serological group of the genus Flavivirus and therefore closely related genetically and antigenically. They share a number of properties, including the use of birds as their major wildlife maintenance host and Culicine mosquitoes for transmission, and they are both associated with severe human disease, as well as fatal infections in horses.
The emergence of these two viruses, and their well-established propensity to colonise new areas, make it timely to re-examine their ecology, biology, molecular structure, replication and epidemiology, and these therefore provide the focus of this volume.

Environmental Chemistry is a relatively young science. Interest in this subject, however, is growing very rapidly and, although no agreement has been reached as yet about the exact content and limits of this interdisciplinary subject, there appears to be increasing interest in seeing environmental topics which are based on chemistry embodied in this subject. One of the first objectives of Environ mental Chemistry must be the study of the environment and of natural chemical processes which occur in the environment. A major purpose of this series on Environmental Chemistry, therefore, is to present a reasonably uniform view of various aspects of the chemistry of the environment and chemical reactions occurring in the environment. The industrial activities of man have given a new dimension to Environ mental Chemistry. We have now synthesized and described over five million chemical compounds and chemical industry produces about one hundred and fifty million tons of synthetic chemicals annually. We ship billions of tons of oil per year and through mining operations and other geophysical modifications, large quantities of inorganic and organic materials are released from their natural deposits. Cities and metropolitan areas of up to 15 million inhabitants produce large quantities of waste in relatively small and confined areas. Much of the chemical products and waste products of modern society are released into the environment either during production, storage, transport, use or ultimate disposal. These released materials participate in natural cycles and reactions and frequently lead to interference and disturbance of natural systems."

Seasonal patterns have been found in a remarkable range of health conditions, including birth defects, respiratory infections and cardiovascular disease. Accurately estimating the size and timing of seasonal peaks in disease incidence is an aid to understanding the causes and possibly to developing interventions. With global warming increasing the intensity of seasonal weather patterns around the world, a review of the methods for estimating seasonal effects on health is timely.

This is the first book on statistical methods for seasonal data written for a health audience. It describes methods for a range of outcomes (including continuous, count and binomial data) and demonstrates appropriate techniques for summarising and modelling these data. It has a practical focus and uses interesting examples to motivate and illustrate the methods. The statistical procedures and example data sets are available in an R package called season ."

The probability for exposure to damaging radiation, toxic chemicals in the environment and adverse biological agents has increased exponentially today. The more frequent and faster travel that we experience today also escalates the risk of contraction and transmission of potentially deadly infections. This has created a very real and escalating risk for injuries and deaths. This is accentuated in the military and medical staff that is more frequently exposed to radiological, chemical, and biological agents in their normal working environment. Understanding the mechanisms whereby these toxic agents inflict damage to our bodies is essential to prepare us for these challenges. Much of the damage is inflicted through the generation of free radicals and non-radical oxidants which then act through oxidative mechanisms to injury the body. This volume will discuss the damage caused by these radiological, chemical, and biological environmental stressors, the mechanisms through which the damage can occur and the novel strategies that can be used to reduce the injury inflicted by these toxic compounds. Using basic and clinical research approaches, the contents of this book discuss new ideas for the development of bioactive products and environmental approaches to lessen or negate the biological damage inflicted by these noxious compounds.

Since questions about wireless phones andbrain cancer were first raised in early 1993, numerous scientificstudies and reviews have been conducted and published throughout the world with support from industry and government. The most comprehensive colloquium to date covering this science was co sponsored byt he International Committee on WirelessCommunication Health Research and Wireless Technology Research, LLC,a t the University "La Sapienza" ofR omein November 1995. Papers fromt hat colloquium with appropriate updates formt he foundation for the current volume. A follow up tothat colloquium isbeing planned fort he spring of 1999 byt he same group and thereport of that colloquium will bet he basis for Volume II ofthis series. As thescientific story about wireless phones and health effects continues to unfold over the next several years, it is important to evaluate thework ina context t hat isb eneficialt ot he enhancement ofpublic health. Two themesa re critical to an appropriate contextual understanding ofthis science.

In a new era of global health diplomacy, the most important tool for decision-making is negotiation. Globalization is binding countries, issues and people together as never before. In the domain of public health, traditional international concerns like the spread of infectious diseases have been joined by new concerns and challenges in managing the health impacts of trade and intellectual property rights, and by new opportunities to create effective global public health agreements and programs. To address the major health crises of today and to prevent or mitigate them in the future, countries must seek collective agreement and action within and across their borders. However, the world of international negotiation is not the world in which health decision-makers reside or are most comfortable. The goal of this guide is to provide health policy-makers with practical information and negotiation tools, to help them create better international health agreements and programs. "This is the best book I know to help health professionals develop the negotiation skills necessary to meet the challenges of global health diplomacy. It is filled with wise advice and invaluable tools for success." Professor Jeswald W. Salacuse, The Fletcher School of Law and Diplomacy, Tufts University

As part of its "Programme for the prevention of health hazards caused by industrial substances", the Berufsge- nossenschaft der chemischen Industrie (BG Chemie, Em- ployment Accident Insurance Fund of the Chemical Indus- try) began in 1977 to investigate the toxicity of those chemicals which are widely used, have many different ap- plications and are suspected of being dangerous to health, in particular of having long-term effects. The in- vestigations consist of a literature search and - depending on the results - commissions of experimental studies. It is hoped by means of this testing to close gaps in our know- ledge and to increase the scientific validity of the required risk assessments. The results of the toxicological in- vestigations carried out by BG Chemie, and the resulting substance assessments have been published in German since 1987 in the form of 113 "Toxikologische Bewer- tungen" ("Toxicological Evaluations") up to now. In order to make this useful information internation- ally available, BG Chemie began in October 1990 to pub- lish them as a book series in English, of which the fifth vol- ume (containing 12 individual evaluations) is presented here. Therefore for 72 existing chemicals "Toxicological Evaluations" are available in English at the moment, a fur- ther 38 are in preparation and will be published soon.

"Toxicological Evaluations" are critically assessed data and recommendationsfor occupational safety officers, industrial hygienists, and human and animal toxicologists. They are compiled and constantly reviewed under internationally coordinated programms for establishing the risk potential of existing chemicals to prevent health hazards at the working place. Data for the following 61 chemicals have been published in the series: Acrylic acid, Benzalchloride, Benzotrichloride, Benzoylchloride, Benzylchloride, Bromoform, Butynediol, gamma-Butyrolactone, 4-Chloro-2-nitroaniline, Chloro acetic acid methyl ester, Chloroacetamide, o-Chlorobenzotrichloride, p-Chlorobenzotrichloride, o-Chlorobenzotrifluoride, m-Chlorobenzotrifluoride, Chloroformic acid ethyl ester, 4-Chlorophenyl isocyanate, m-Cresidine, N, N'-Di-sec.-butyl-p-phenylenediamine, 1,4-Diaminoanthraquinone, 1,4-Dicyanobutane, Dicyclopentadiene, Diethanolamine, Diethylcarbamoyl chloride, Diethyliene glycol, Diglycidyl ether, Diisopropanolamine, Dimethyl therephthalate, 2,4-Dinitromethylaniline, Ethylene thiourea, 2-Ethylhexanal, 2-Ethylhexanol, Hydrazobenzene, Isopropyl ethylene glycol ether, Maleic acid dimethyl ester, Manganese dioxide, 2-Mercaptobenzothiazole, Methoxyacetic acid, Methylbutadiene -1,3, 3-Methylbutanol-1, 2-Methylpropanol-1, 2-Methylpropene, Monochloroacetic acid, 1,5-Naphthalene diamine, 5-Nitro-2-aminotoluene, m-Nitroaniline, 5-Nitroanisidine, p-Nitrosophenol, Phenyl isocyanate, Phenylglycidyl ether, o-Phthalodinitrile, Propargyl alcohol Sodium hypochlorite, Therephthalic acid, Thiram, Tributyl phosphate, Triethanolamine, Triethylene tetramine, Trimethylphenyl-ammonium chloride, Trimethylquinone, Vinyl fluoride.

This series is dedicated to serving the growing community of scholars and practitioners concerned with the principles and applications of environmental management. Each volume is a thorough treatment of a specific topic of importance for proper management practices. A fundamental objective of these books is to help the reader discern and implement man's stewardship of our environment and the world's renewable resources. For we must strive to understand the relation ship between man and nature, act to bring harmony to it, and nurture an environment that is both stable and productive. These objectives have often eluded us because the pursuit of other individual and societal goals has diverted us from a course of living in balance with the environment. At times, therefore, the environmental manager may have to exert restrictive control, which is usually best applied to man, not nature. Attempts to alter or harness nature have often failed or backfired, as exemplified by the results of imprudent use of herbicides, fertilizers, water, and other agents. Each book in this series will shed light on the fundamental and applied aspects of environmental management. It is hoped that each will help solve a practical and serious environmental problem."