Pathology of Asbestos-Associated Diseases integrates the newest research and advances in its discussion of asbestos-induced diseases. Organized in 13 chapters, the book begins with background information on the mineralogy of asbestos, occupation and environmental exposure to asbestos, and asbestosis. A detailed discussion on mesothelioma includes a historical background, addresses etiologic considerations and epidemiology, pathologic features, differential diagnosis and treatment and prognosis. Guidelines for assessing and identifying asbestos-associated carcinomas of the lung, including histopathology and differential diagnosis, are discussed. The text also addresses the explosion of research in the area of molecular biology and the abundance of information bearing on the mechanisms by which asbestos causes disease. Chapters also cover cytopathology and experimental models of asbestos-related diseases. The diseases associated with asbestos have significant medico-legal implications, and there are two chapters dedicated to addressing the issue. More than 190 illustrations complement the text. An invaluable reference for the pathologist, pulmonologist, radiologist, and occupational medical practitioner interested in asbestos-related disease as well as malpractice attorneys needing an understanding of asbestos, the diseases it induces, prognosis and clinical implications.

This volume contains the Proceedings of the XVIIth ISAC Meeting held in Valladolid, Spain, July 1-5, 2008. As such, it contains the most permanent records of the combined efforts of all attendants. The meeting was held at the School of Medicine of Valladolid, that had the privilege of a recent celebration. The celeb- tion was none other than its 600th anniversary, implying that all participants were surrounded by historical landmarks, from the historical building of the University, to the Museum of polychrome sculpture of Valladolid, to the Monastery of Clarisas in Tordesillas, to the beauty and charm of Salamanca. In this ambience we had three days of intense work, distributed in several oral sessions, preceded by plenary lectures given by our invited speakers who were kind enough to provide us with the latestprogressintheirspeci c elds. We also hadtimeallottedtoposterviewing. As regularattendantsto the XVIIth ISACMeeting, we want to expressourappreciation forthevaluablediscussionssurroundingeachposter, theenthusiasticpresentationof data, the comments of colleagues with suggestions for improvement, and the plans for collaborations that emerged from these discussions. Needless to say that XVIIth ISAC Meeting was the fruit of many collabo- tive efforts. The Local Organizing Committee pro ted from the advice of several colleagues from around the world, namely, Prof. Chris Peers from Leeds, UK, Prof. Prem Kumar from Birmingham, UK, Prof. Nanduri Prabhakar from Chicago, USA, Prof. Colin Nurse from Hamilton, Canada, and Prof. Rodrigo Iturriaga from Santiago, Chile

This is an essential portable handbook on bioterrorism and disaster medicine. Its practical and comprehensive text features chapters pertinent to bioterrorism, infectious disease, microbiology, virology, public health, epidemiology, and disaster medicine. It will serve as a practical guide for situation-specific disasters; recognize what injuries or illnesses to expect; provide proactive guidelines to define specific diseases; and give a guide of appropriate personnel protective equipment during these large-scale emergencies. It is an essential companion to those either interested or currently working in any of the aforementioned fields.

This volume addresses a broad spectrum of the environmental issues surrounding organic bromine and iodine compounds. It covers their partition among the environmental compartments and the potential for their long-range dissemination. The important issue of their atmospheric chemistry is discussed in detail in the context of ozone depletion and global warming, and the significant difference between the reactions of methyl bromide and methyl iodide are underscored. The mammalian toxicity is discussed and the mechanisms of the degradation and transformation of organic bromine and iodine compounds addressed. There has been considerable interest in naturally occurring metabolites in the current debate on the fate and partition of methyl bromide that is an important fungicide and is produced in substantial quantities as a metabolite of marine algae. The possible natural occurrence of diphenyl ethers that are used as flame retardants have also been raised. A discussion is given on plausible mechanisms for the biosynthesis of representative organic bromine and organic iodine metabolites. Reaction pathways are illustrated throughout and comprehensive references are given.

The quality of food is such a live issue at the moment that this title is an essential tool for researchers in a variety of disciplines. It provides a review of the key features of trace elements in soils, plants and the food web on which human beings survive. The authors' intention is to summarize up-to-date interdisciplinary data for the concise presentation of our understanding of trace-element transfer in the chain from soil to man.

At last a second edition of this hugely important text that reflects the progress and experience gained in the last decade and aims at providing background and training material for a new generation of risk assessors. The authors offer an introduction to risk assessment of chemicals as well as basic background information on sources, emissions, distribution and fate processes for the estimation of exposure of plant and animal species in the environment and humans exposed via the environment, consumer products, and at the workplace. The coverage describes the basic principles and methods of risk assessment within their legislative frameworks (EU, USA, Japan and Canada).

Lessons in Environmental Microbiology provides an understanding of the microbial processes used in the environmental engineering and science fields. It examines both basic theory as well as the latest advancements in practical applications, including nutrient removal and recovery, methanogenesis, suspended growth bioreactors, and more. The information is presented in a very user-friendly manner; it is not assumed that readers are already experts in the field. It also offers a brief history of how microbiology relates to sanitary practice, and examines the lessons learned from the great epidemics of the past. Numerous worked example problems are presented in every chapter.

In 2004 an amount of 187 tons of palladium has been sold in world market. The main demands were automotive catalyst (58%), electronics (14%), jewellery (14%) and dental practises (13%). Especially, the increasing use of palladium in catalytic converters is a reason for substantial research in this field. Emission, environmental distribution and possible health effects of pla- num have been summarized detailed in two recent books "Emissionen von Platinmetallen: Analytik, Umwelt- und Gesundheitsrelevanz" and "Anth- pogenic Platinum Group Emissions - Their Impact on Man and Envir- ment" published by Springer in 1999 and 2000 (Zereini & Alt (Eds)). But there is a clear lack of information concerning palladium. It is very imp- tant to condense the present state of research findings from emission to potential health risks for the environment and humans. Very important is the chapter about analytical determination of pal- dium, which shows clearly the problems of several analytical techniques. Some data published during the last decade have to be re-evaluated because of insufficient analytical techniques. Also the finding that palladium c- pounds are relatively soluble and mobile in environmental settings is a great issue for further investigations. I think it is the right time for such a comprehensive book about palladium research and I am sure that readers with different scientific background like chemists, biologists, geologists medical doctors e.g. will benefit very much from reading this book.

Oxidative stress is one of the major symptoms accompanying physiological functions and numerous diseases. Oxidants and free radicals are connected with diseases such as cancer, diabetes, infectious, cardiovascular and neurodegenerative diseases and also in the aging process itself. Therefore, comprehensive knowledge of the underlying mechanisms of oxidant and free radical production and the defence against this permanent threat to cells is important for the understanding of many physiological and pathophysiological processes. This book overviews the basic mechanisms of oxidant formation and antioxidant defences. In addition, the formation of oxidants and their detoxification, the damage of macromolecules and the major repair and removal systems will be highlighted.

"Musculoskeletal, Sports, and Occupational Medicine: Rehabilitation Medicine Quick Reference" provides the core knowledge the busy practitioner needs to deliver top-notch rehabilitative care to patients with musculoskeletal, sports, or occupational injuries. Covering 107 alphabetically arranged topics from Achilles Tendinopathy to Whiplash, this nuts and bolts resource is designed to provide concise and accurate information. The book begins with a template for evaluating a patient with musculoskeletal injury, and covers the full gamut of conditions and sequelae commonly seen by practitioners dealing with bone, joint, and soft tissue problems in athletes, injured workers, and individuals of any age with musculoskeletal issues.

Every entry is standardized for quick look-up in the office or clinic, and features description, etiology, risk factors, clinical features, natural history, diagnosis, red flags, treatment, prognosis, helpful hints and suggested readings.

Every entry is standardized for quick look-up in the office or clinic, and features description, etiology, risk factors, clinical features, natural history, diagnosis, red flags, treatment, prognosis, helpful hints, and suggested readings. All "Rehabilitation Medicine Quick Reference"titles offer: Consistent Approach and Organization: at-a-glance outline format allows readers to find the facts quickly Concise Coverage: of must-know information broken down into easy-to-locate topics Fast Answers to Clinical Questions: diagnostic and management criteria for problems commonly encountered in daily practice Hands-on Practical Guidance: for all types of interventions and therapies Multi-Specialty Perspective: ensures that issues of relevance to all rehabilitation team members are addressed

The Legacy of Carbon Dioxide: Past and Present Impacts covers the truly varied roles carbon dioxide has played and continues to play in the character of our planet. Chapters address the synthesis of CO2 in stars, the evolution of the atmosphere over billions of years, the chemical and physical properties of CO2 and how those influence common phenomena. How well this knowledge is understood and how it was determined, including existing uncertainties in our confidence and the stress from competing possibilities are discussed. Much of the technological jargon in various incorporated sciences has been modified to ease consumption by the non-expert. Features: Provides a historical panorama on how much the world has changed over the eons and the vast influence of carbon dioxide in these changes Follows CO2 through acidic explosive waters, volcanic episodes, sequestered reservoirs, and the chemistry of life Examines the broad scope of chemical and physical attributes carbon dioxide is capable of and their impacts Much of the technological verbiage in various incorporated sciences has been modified to ease consumption by the non-expert. This book is a valuable resource for readers interested in the science of carbon dioxide as well as natural science, the environment, scientific methods, chemistry, and geological sciences.

This book gives a comprehensive survey of the epidemiology of common environmental exposures, including diet, water, particulates in outdoor air, nitrogen dioxide, ozone, environmental tobacco smoke, radon in homes, electromagnetic fields, and lead. Design and analysis issues, risk assessment and meta-analysis, and future directions in environmental epidemiology are also covered. All chapters provide a review of the literature as well as a discussion of important methodologic issues, particularly exposure assessment and statistical methods. The book's focus is on environmental exposures that are suspected of causing disease, but often remain controversial. Most of these exposures are widespread and low-level, and are thought to increase the risk of chronic diseases that have many causes. Although the disease risks due to these exposures may be low, the public health burden may be important because large numbers of people are exposed. Such exposures are inherently difficult to detect via observational epidemiology. This book seeks to clarify the challenges involved and suggests ways to move forward. It will be useful to students and practitioners of public health, environmental health, and epidemiology.

Many business leaders do not take care of their health. Each chapter of this interactive manual explores an aspect of the health and vitality of the modern business leader, and provides solutions based on up-to-date medical science and more than 20 years' experience at INSEAD with more than 75,000 corporate executives.

This authoritative text on occupational lung disorders builds upon the fundamentals, including clinical, epidemiological, and predictive approaches. It discusses interstitial and malignant diseases, airways diseases, and other respiratory issues, such as diving, working at high altitudes, and abnormal sleep conditions. It also covers related long-term conditions, such as asthma and COPD. This edition has been completely revised and brought up to date for all physicians dealing with pulmonary disorders caused by the environment or the workplace. Print Versions of this book also include access to the ebook version.

Protecting Endangered Species in the United States is a collection of original papers by economists, biologists and political scientists with a common theme--protecting species at risk while safeguarding social order is a policy challenge that entangles biology, politics, and economics. The volume begins by assessing the biological needs that define the endangered species problem. The authors then explore the political realities that delimit the debate--who pays the costs and receives the benefits, and how interest groups affect species protection. The book addresses the economic choices that must be confronted for effective protection strategies including incentive schemes to promote preservation on public and private land.

In September 2005, Yerevan (Armenia) hosted an International Conference dedicated to the 70th anniversary of the publication of the so called green paper, published by N.W. Timofeeff-Ressovsky, K. Zimmer and M. Delbruck in 1935, entitled On the origin of gene mutations and gene structure. The importance of this paper for genetics and radiobiology was enormous - not only for radiobiology, but for genetics in general. The target of the radiation action was indeed the gene, that for the first time found a clear, operational definition. The organisers of this Conference proposed to convene scientists from all over the world to discuss the impact of radiation risk estimates in normal and emergency situations. This was the starting point of the NATO Advanced Research Workshop, whose proceedings are published in this book.

Only ultrasound book that deals specifically with infectious and tropical diseases

This book presents a broad overview of the many intersections between health and the environment that lie at the basis of the most crucial environmental health issues, focusing on the responses provided by international and EU law. Consistent with the One Health approach and moving from the relevant international and EU legal frameworks, the book addresses some of the most important issues of environmental health including the traditional, such as pollution of air, water and soil and related food safety issues, as well as new and emerging challenges, like those linked to climate change, antimicrobial resistance and electromagnetic fields. Applying an intersectoral and interdisciplinary approach, it also investigates other branches of international and EU law including human rights law, investment law, trade law, energy law and disaster law. The work also discusses ethics and intergenerational equity. Ultimately, the book assesses the degree of effectiveness of the international and EU normative framework, and the extent to which the relevant legal instruments contribute to the protection of public health from major environmental hazards. The book will be a valuable resource for students, academics and policy makers working in the areas of Environmental Health law, Global Health law, International law and EU law.

This book provides extensive information on the chemicals that inhabit our environment, our food, our water and our air and the impact that they may be having on human health. The author is a medical scientist, with training in the law. The book documents current understanding about pesticides in food, the plastics revolution, toxic metals, air, water and electronic waste pollutants, chemical exposure in the workplace, radiation pollutants, chemical exposure and hearing loss, how our bodies deal with chemicals, genetic variability and the risk of disease, the effect of chemicals on genes, mitochondria and the immune system and what we can do about it all. Industrialisation has resulted in many thousands of chemicals, which are being continuously developed and often escaping from where they are used into our human environment, without us really knowing enough about them. In high dosages or with continuous small dosage, the evidence suggests, that many of them could interfere with human health and some of them are known to be doing so. But for the vast majority, we are left wondering whether some could be responsible for some diseases the causes of which are inadequately understood. Every chapter is thoroughly reinforced with several pages of references from the peer-reviewed literature.

The subject of medical entomology contin- factors such as insecticide susceptibility, vec- ues to be of great importance. Arthropodborne tor competence, host preference and similar im- diseases such as malaria, yellow fever, dengue portant phenomena. Now, a variety of new and filariasis continue to cause considerable methods are available to study genes, and to human suffering and death. Problems in ani- genetically alter important characteristics in mal production, wildlife and pets of humans vectors as a potential means of controlling hu- caused by arthropods still exact a large eco- man and animal diseases. nomic toll. In the past 2 decades, the invasion Many of the traditional tasks of medical en- of exotic pests and pathogens has presented tomologists continue to be important. Arthro- new problems in several countries, including pod systematics is important because the need the USA. For example, the year 1999 saw the for accurate identification of arthropods is vital invasion of the eastern USA by Aedes japonicus, to an understanding of natural disease cycles. an Asian mosquito, and West Nile virus, a mos- Systematics has been made even more challeng- quito-transmitted African arbovirus related to ing because of the current appreciation of the St. Louis encephalitis virus. number of groups of sibling species among vec- At the same time old and new health prob- tors of important disease pathogens. New mo- lems with arthropods occur, the traditional ap- lecular tools are assisting in separating these proaches to arthropod control have become forms.

This is a thorough revision and update of the highly successful first edition, which which achieved sales in excess of 4,500. The text serves as a comprehensive introduction to parasitology for both undergraduate and beginning graduate students. In this edition, particular emphasis is placed on parasites of human and veterinary importance. The first three chapters in the text are concerned with how parasites 'work, ' their biochemistry, molecular and cell biology and physiology. The remaining chapters cover ecology and epidemiology, immunology and chemotherapy, with the final chapter covering integrated control. This new edition contains new material on cell and molecular biology, vectors and control, which is in contrast to the general biological approach of the first edition. The second edition will succeed the first as the major text on parasitology for students in biology, zoology, microbiology, medicine, veterinary medicine, tropical medicine and public health

This open access book not only describes the challenges of climate disruption, but also presents solutions. The challenges described include air pollution, climate change, extreme weather, and related health impacts that range from heat stress, vector-borne diseases, food and water insecurity and chronic diseases to malnutrition and mental well-being. The influence of humans on climate change has been established through extensive published evidence and reports. However, the connections between climate change, the health of the planet and the impact on human health have not received the same level of attention. Therefore, the global focus on the public health impacts of climate change is a relatively recent area of interest. This focus is timely since scientists have concluded that changes in climate have led to new weather extremes such as floods, storms, heat waves, droughts and fires, in turn leading to more than 600,000 deaths and the displacement of nearly 4 billion people in the last 20 years. Previous work on the health impacts of climate change was limited mostly to epidemiologic approaches and outcomes and focused less on multidisciplinary, multi-faceted collaborations between physical scientists, public health researchers and policy makers. Further, there was little attention paid to faith-based and ethical approaches to the problem. The solutions and actions we explore in this book engage diverse sectors of civil society, faith leadership, and political leadership, all oriented by ethics, advocacy, and policy with a special focus on poor and vulnerable populations. The book highlights areas we think will resonate broadly with the public, faith leaders, researchers and students across disciplines including the humanities, and policy makers.

The advent of tropical medicine was a direct consequence of European and American imperialism, when military personnel, colonial administrators, businessmen, and settlers encountered a new set of diseases endemic to the tropics. Professor Farley describes how governments and organizations in Britain, the British colonies, the United States, Central and South America, South Africa, China, and the World Health Organization faced one particular tropical disease, bilharzia or schistosomiasis. Bilharzia is caused by a species of blood vessel-inhabiting parasitic worms and today afflicts over 200 million people in seventy-four countries. John Farley demonstrates that British and American imperial policies and attitudes largely determined the nature of tropical medicine. Western medical practitioners defined the type of medical system that was imposed on the indigenous populations; they dictated which diseases were important and worthy of study, which diseases were to be controlled, and which control methods were to be used.

A novel methodology is put forward in this book, which empowers researchers to investigate and identify potential spatial processes among a set of regions. Spatial processes and their underlying functional spatial relationships are commonly observed in the geosciences and related disciplines. Examples are spatially autocorrelated random variables manifesting themselves in distinct global patterns as well as local clusters and hot spots, or spatial interaction leading to stochastic ties among the regions. An example from observational epidemiology demonstrates the flexibility of Moran's approach by analyzing the spatial distribution of cancer data from several perspectives. Recent advances in computing technology, computer algorithms, statistical techniques and global and local spatial patterns by means of Moran's "I" feasability. Moran's "I" is an extremely versatile tool for exploring and analyzing spatial data and testing spatial hypotheses.

Biologically Active Natural Products: Pharmaceuticals demonstrates the connections between agrochemicals and pharmaceuticals and explores the use of plants and plant products in the formulation and development of pharmaceuticals. Experts from around the world examine a multitude of topics, including evaluation of extracts from tropical plants for potential anticancer activity and cancer chemopreventive activity; use of Chinese lacquer tree sap products as pharmaceutical intermediates; and new approaches to drug discovery from the rainforest.