Humans and flies look nothing alike, yet their genetic circuits are remarkably similar. Here, Lewis I. Held, Jr compares the genetics and development of the two to review the evidence for deep homology, the biggest discovery from the emerging field of evolutionary developmental biology. Remnants of the operating system of our hypothetical common ancestor 600 million years ago are compared in chapters arranged by region of the body, from the nervous system, limbs and heart, to vision, hearing and smell. Concept maps provide a clear understanding of the complex subjects addressed, while encyclopaedic tables offer comprehensive inventories of genetic information. Written in an engaging style with a reference section listing thousands of relevant publications, this is a vital resource for scientific researchers, and graduate and undergraduate students.

The first comprehensive look at menopause from prehistory to today Are the ways we look at menopause all wrong? Historian Susan Mattern says yes, and The Slow Moon Climbs reveals just how wrong we have been. Taking readers from the rainforests of Paraguay to the streets of Tokyo, Mattern draws on historical, scientific, and cultural research to reveal how our perceptions of menopause developed from prehistory to today. For most of human history, people had no word for menopause and did not view it as a medical condition. Rather, in traditional foraging and agrarian societies, it was a transition to another important life stage. This book, then, introduces new ways of understanding life beyond fertility. Mattern examines the fascinating "Grandmother Hypothesis"-which argues for the importance of elders in the rearing of future generations-as well as other evolutionary theories that have generated surprising insights about menopause and the place of older people in society. She looks at agricultural communities where households relied on postreproductive women for the family's survival. And she explores the emergence of menopause as a medical condition in the Western world. It was only around 1700 that people began to see menopause as a dangerous pathological disorder linked to upsetting symptoms that rendered women weak and vulnerable. Mattern argues that menopause was another syndrome, like hysterical suffocation or melancholia, that emerged or reemerged in early modern Europe in tandem with the rise of a professional medical class. The Slow Moon Climbs casts menopause, at last, in the positive light it deserves-not only as an essential life stage, but also as a key factor in the history of human flourishing.

The greatest mass extinction in Earth's history happened some 251 million years ago. In this cataclysm at least 90% of life was killed, both on land and in the sea, almost bringing evolution to a halt. What caused destruction on such an unimaginable scale? Was it the impact of a huge meteorite, or prolonged volcanic eruption in Siberia? In this acclaimed book, now updated to include the most recent research and findings, Michael Benton assembles all the evidence and gives his verdict.

Ecology studies biodiversity in its variety and complexity. It describes how species distribute and perform in response to environmental changes. Ecological processes and structures are highly complex and adaptive. In order to quantify emerging ecological patterns and investigate their hidden mechanisms, we need to rely on the simplicity of mathematical language. Ecological patterns are emerging structures observed in populations, communities and ecosystems. Elucidating drivers behind ecological patterns can greatly improve our knowledge of how ecosystems assemble, function and respond to change and perturbation. Mathematical ecology has, thus, become an important interdisciplinary research field that can provide answers to complex global issues, such as climate change and biological invasions. The aim of this book is to (i) introduce key concepts in ecology and evolution, (ii) explain classic and recent important mathematical models for investigating ecological and evolutionary dynamics, and (iii) provide real examples in ecology/biology/environmental sciences that have used these models to address relevant issues. Readers are exposed to the key concepts, frameworks, and terminology in the studies of ecology and evolution, which will enable them to ask the correct and relevant research questions, and frame the questions using appropriate mathematical models.

Lemurs share a common distant ancestor with humans. Following their own evolutionary pathway, lemurs provide the ideal model to shed light on the behavioural traits of primates including conflict management, communication strategies and society building and how these aspects of social living relate to those found in the anthropoid primates. Adopting a comparative approach throughout, lemur behaviour is cross-examined with that of monkeys, apes and humans. This book reviews and expands upon the newest fields of research in lemur behavioural biology, including recent analytical approaches that have so far been limited to studies of haplorrhine primates. Different methodological approaches are harmonised in this volume to break conceptual walls between both primate taxa and different disciplines. Through a focus on the methodologies behind lemur behaviour and social interactions, future primate researchers will be encouraged to produce directly comparable results.

Our experience of the world is driven by processes common to all animals: growth, survival, reproduction and death. Evolution and Human Behaviour explores the complexities of the human experience through the lens of Darwinism, drawing on a long and vibrant tradition of different theories and interpretations. This textbook offers a compelling synthesis of key concepts, addressing human thought, feeling and behaviour in fundamental evolutionary terms. This is a essential text for undergraduate students taking courses in psychology, human biology, ethology, anthropology and human behavioural ecology, providing an insightful and comprehensive introduction for anyone who wishes to understand how human behaviour has evolved. New to this Edition: - Additional chapters on health and disease, homosexuality, the nature of adaptations and life history theory. - Includes brand-new material on epigenetics, patterns of crime, error management theory, moral foundations theory, religion and gene culture co-evolution. - Now accompanied by a companion website offering additional reading material and useful practice questions - New 'controversy' boxes in each chapter, providing ideas for essay topics and classroom discussion

A billion-year history of movement, from bacteria to Olympic athletes. 'Packed with revelations, scholarly but clear, Restless Creatures carries you from the kinetics of the amoeba to that of the blue whale, from the swim-cycle of spermatozoa, to why skipping works best on the moon. A pop-science treat.' Gavin Francis, author of Adventures in Human Being Despite the overwhelming diversity of life on earth, one theme has dominated its evolution: the apparently simple act of moving from one place to another. Restless Creatures is the first book for a general audience telling the incredible story of locomotion in human and animal evolution. Evolutionary biologist Matt Wilkinson traces this 4-billion-year history, showing why our ancestors became two-legged, how movement explains why we have opposable thumbs and a backbone, how fish fins became limbs, how even trees are locomotion-obsessed, and how movement has shaped our minds as well as our bodies. He explains why there are no flying monkeys or biological wheels, how dinosaurs took to the air, how Mexican waves were the making of the animal kingdom, and why moving can make us feel good. Restless Creatures opens up an astonishing new perspective - that little in evolution makes sense unless in the light of movement.

When was the human threshold crossed? What is the evidence for evolving humans and their emerging humanity? This volume explores in a global overview the archaeology of the Middle Pleistocene, 800,000 to 130,000 years ago when evidence for innovative cultural behaviour appeared. The evidence shows that the threshold was crossed slowly, by a variety of human ancestors, and was not confined to one part of the Old World. Crossing the Human Threshold examines the changing evidence during this period for the use of place, landscape and technology. It focuses on the emergence of persistent places, and associated developments in tool use, hunting strategies and the control of fire, represented across the Old World by deeply stratified cave sites. These include the most important sites for the archaeology of human origins in the Levant, South Africa, Asia and Europe, presented here as evidence for innovation in landscape-thinking during the Middle Pleistocene. The volume also examines persistence at open locales through a cutting-edge review of the archaeology of Northern France and England. Crossing the Human Threshold is for the worldwide community of students and researchers studying early hominins and human evolution. It presents new archaeological data. It frames the evidence within current debates to understand the differences and similarities between ourselves and our ancient ancestors.

'Thrilling, provocative and mind-expanding' Mail on Sunday 'Masterful and illuminating' DAVID EAGLEMAN Dr Joseph Jebelli takes us on a seven-million-year journey through our own heads, drawing on insights from neuroscience, evolutionary biology, psychology, and philosophyto reveal how our brain's evolution turned us into Homo sapiens and beyond. Discover how memory has almost nothing to do with the past; magic mushroom use might be responsible for our intelligence; and how autism teaches us hugely positive lessons about our past and future. A single mutation is all it takes. 'Written with aplomb and an eye for arresting asides . . . This is an accessible and thought-provoking book' The Times

This book discusses the hypothesis that the primate pulvinar contains an original scaffold which is derived from cytoarchitectural markers and specific protein distributions. Thereafter, along primate evolution, different selective pressures acted in order to shape and fine-tune the connectivity of the pulvinar with specific regions of the neocortex. This divergence created, among other things, the different sets of retinotopic map representations in the pulvinar nucleus depending on functional and behavioral requirements of each species. The pulvinar, the largest nucleus of the primate thalamus, has extensive and reciprocal connections with several areas of the neocortex. These input-output loops suggest that the pulvinar may regulate the flow of information within and between cortical areas in a highly dynamic fashion. Therefore, understanding the anatomical subdivisions within the pulvinar, and its connectivity with the cortex, is paramount to understanding pulvinar physiological function. However, there is a stark contrast regarding the way that the pulvinar is subdivided depending on the technique employed. Cytoarchitectural and immunohistochemical methods reveal a very similar pattern of pulvinar subdivision across Old- and New-World monkeys. On the other hand, electrophysiological and connectivity studies expose clear discrepancies in pulvinar organization across primate evolution.

Mental disorders arise from neural and psychological mechanisms that have been built and shaped by natural selection across our evolutionary history. Looking at psychopathology through the lens of evolution is the only way to understand the deeper nature of mental disorders and turn a mass of behavioral, genetic, and neurobiological findings into a coherent, theoretically grounded discipline. The rise of evolutionary psychopathology is part of an exciting scientific movement in psychology and medicine - a movement that is fundamentally transforming the way we think about health and disease. Evolutionary Psychopathology takes steps toward a unified approach to psychopathology, using the concepts of life history theory - a biological account of how individual differences in development, physiology and behavior arise from tradeoffs in survival and reproduction - to build an integrative framework for mental disorders. This book reviews existing evolutionary models of specific conditions and connects them in a broader perspective, with the goal of explaining the large-scale patterns of risk and comorbidity that characterize psychopathology. Using the life history framework allows for a seamless integration of mental disorders with normative individual differences in personality and cognition, and offers new conceptual tools for the analysis of developmental, genetic, and neurobiological data. The concepts presented in Evolutionary Psychopathology are used to derive a new taxonomy of mental disorders, the Fast-Slow-Defense (FSD) model. The FSD model is the first classification system explicitly based on evolutionary concepts, a biologically grounded alternative to transdiagnostic models. The book reviews a wide range of common mental disorders, discusses their classification in the FSD model, and identifies functional subtypes within existing diagnostic categories.

1. 1 Nautilus and Allonautilus: Two Decades of Progress W. Bruce Saunders Department of Geology Bryn Mawr College Bryn Mawr PA 19010 wsaunder@brynmawr. edu Neil H. Landman Division of Paleontology American Museum of Natural History New York, New York 10024 landman@amnh. org When Nautilus: Biology and Paleobiology of a Living Fossil was published in 1987, it marked a milestone in cross-disciplinary collaboration. More than half of the contributing authors (36/65) were paleontologists, many of whom were collaborating with neontological counterparts. Their interest in studying this reclusive, poorly known animal was being driven by a search for clues to the mode of life and natural history of the once dominant shelled cephalopods, through study of the sole surviving genus. At the same time, Nautilus offered an opportunity for neontologists to look at a fundamentally different, phylogenetically basal member of the extant Cephalopoda. It was a w- win situation, combining paleontological deep-time perspectives, old fashioned expeditionary zeal, traditional biological approaches and new techniques. The results were cross-fertilized investigations in such disparate fields as ecology, functional morphology, taphonomy, genetics, phylogeny, locomotive dynamics, etc. As one reviewer of the xxxvi Introduction xxxvii book noted, Nautilus had gone from being one of the least known to one of the best understood of living cephalopods.

Written for non-experts, this volume introduces the mechanisms that underlie reticulate evolution. Chapters are either accompanied with glossaries that explain new terminology or timelines that position pioneering scholars and their major discoveries in their historical contexts. The contributing authors outline the history and original context of discovery of symbiosis, symbiogenesis, lateral gene transfer, hybridization or divergence with gene flow and infectious heredity. By applying key insights from the areas of molecular (phylo)genetics, microbiology, virology, ecology, systematics, immunology, epidemiology and computational science, they demonstrate how reticulate evolution impacts successful survival, fitness and speciation. Reticulate evolution brings forth a challenge to the standard Neo-Darwinian framework, which defines life as the outcome of bifurcation and ramification patterns brought forth by the vertical mechanism of natural selection. Reticulate evolution puts forward a pattern in the tree of life that is characterized by horizontal mergings and lineage crossings induced by symbiosis, symbiogenesis, lateral gene transfer, hybridization or divergence with gene flow and infective heredity, making the “tree of life� look more like a “web of life.� On an epistemological level, the various means by which hereditary material can be transferred horizontally challenges our classic notions of units and levels of evolution, fitness, modes of transmission, linearity, communities and biological individuality. The case studies presented examine topics including the origin of the eukaryotic cell and its organelles through symbiogenesis; the origin of algae through primary and secondary symbiosis and dinoflagellates through tertiary symbiosis; the superorganism and holobiont as units of evolution; how endosymbiosis induces speciation in multicellular life forms; transferrable and non-transferrable plasmids and how they symbiotically interact with their host; the means by which pro- and eukaryotic organisms transfer genes laterally (bacterial transformation, transduction and conjugation as well as transposons and other mobile genetic elements); hybridization and divergence with gene flow in sexually-reproducing individuals; current (human) microbiome and viriome studies that impact our knowledge concerning the evolution of organismal health and acquired immunity; and how symbiosis and symbiogenesis can be modelled in computational evolution.

The book integrates our understanding of the factors and processes underlying the evolution of multicellularity by providing several complementary perspectives (both theoretical and experimental) and using examples from various lineages in which multicellularity evolved. Recent years marked an increased interest in understanding how and why these transitions occurred, and data from various fields are providing new insights into the forces driving the several independent transitions to multicellular life as well as into the genetic and molecular basis for the evolution of this phenotype. The ultimate goal of this book is to facilitate the identification of general and unifying principles and mechanisms.

This book details a model of consciousness supported by scientific experimental data from the human brain. It presents how the Corollary Discharge of Attention Movement (CODAM) neural network model allows for a scientific understanding of consciousness as well as provides a solution to the Mind-Body problem. The book provides readers with a general approach to consciousness that is powerful enough to lead to the inner self and its ramifications for the vast range of human experiences. It also offers an approach to the evolution of human consciousness and features chapters on mental disease (especially schizophrenia) and on meditative states (including drug-induced states of mind). Solving the Mind-Body Problem bridges the gap that exists between philosophers of mind and the neuroscience community, allowing the enormous weight of theorizing on the nature of mind to be brought to earth and put under the probing gaze of the scientific facts of life and mind.

Three major aspects that distinguish this book are that (1) it contains the most detailed analysis of the sexual reproduction (oogenesis, fertilization and embryonic incubation) in a particular phylum of the aquatic invertebrates (Bryozoa) ever made; this analysis is based on an exhaustive review of the literature on that topic published over the last 260 years, as well as extensive original histological, anatomical and morphological data obtained during studies of both extant and extinct species; (2) this broad analysis has made it possible to reconstruct the major patterns, stages and trends in the evolution of sexual reproduction in various bryozoan clades, showing numerous examples of parallelisms during transitions from broadcasting to embryonic incubation, from planktotrophic to non-feeding larvae and from lecithotrophy to placentation; corresponding shifts in oogenesis, fertilization and embryonic development are discussed in detail; and (3) the key evolutionary novelties acquired by Bryozoa are compared with similar innovations that have evolved in other groups of marine invertebrates, showing the general trends in the evolution of their sexual reproduction. Ecological background of these innovations is considered too. Altogether these aspects make the monograph an “Encyclopedia of bryozoan sexual reproduction,� offering an integral picture of the evolution of this complex phenomenon.

Assembles a collection of experts to provide a current account of different approaches (e.g., traditional, comparative and experimental) being applied to study mobility. Moreover, the book aims to stimulate new theoretical perspectives that adopt a holistic view of the interaction among intrinsic (i.e. skeletal) and extrinsic (i.e. environmental) factors that influence differential expression of mobility. Since the environment undoubtedly impacts mobility of a wide variety of animals, insights into human mobility, as a concept, can be improved by extending approaches to investigating comparable environmental influences on mobility in animals in general. The book teases apart environmental effects that transcend typical categories (e.g., coastal versus inland, mountainous versus level, arboreal versus terrestrial). Such an approach, when coupled with a new emphasis on mobility as types of activities rather than activity levels, offers a fresh, insightful perspective on mobility and how it might affect the musculoskeletal system.

This book represents a cutting-edge contribution giving an all-around perspective of eco-immunology today. Beside questions of the utmost importance for the whole community of immunologists, e.g, the intrinsic limits of immunological experiments performed at the bench on a limited number of selected models, the book covers several other facets of the eco-immunological approach, including host-parasite interactions, human aging and population immunology. Throughout the book the importance of population dynamics and evolutionary diversification of immune systems is frequently recalled, and makes the reader aware of the basic similarities and differences existing between humans and the models adopted for studying human immune system. The evidenced differences have been recently challenging the reliability of several established animal models and in the book it is discussed for the first time in analytical terms whether mice are reliable models of human inflammatory disorders.

This volume explains the key ideas, questions and methods involved in studying the hidden world of vibrational communication in animals. The authors dispel the notion that this form of communication is difficult to study and show how vibrational signaling is a key to social interactions in species that live in contact with a substrate, whether it be a grassy lawn, a rippling stream or a tropical forest canopy. This ancient and widespread form of social exchange is also remarkably understudied. A frontier in animal behavior, it offers unparalleled opportunities for discovery and for addressing general questions in communication and social evolution. In addition to reviews of advances made in the study of several animal taxa, this volume also explores topics such as vibrational communication networks, the interaction of acoustic and vibrational communication, the history of the field, the evolution of signal production and reception and establishing a common vocabulary.

Determining the precise timing for the evolutionary origin of groups of organisms has become increasingly important as scientists from diverse disciplines attempt to examine rates of anatomical or molecular evolution and correlate intrinsic biological events to extrinsic environmental events. Molecular clock analyses indicate that many major groups are twice as old, or more, than a literal reading of the fossil record attests, implying that the fossil record is incomplete. Few paleontologists agree that the fossil record is inadequate, arguing instead that our understanding of the molecular clock is far from ideal. Telling the Evolutionary Time: Molecular Clocks and the Fossil Record represents a discussion between molecular biologists and paleontologists, in which they investigate the significance of competing sources of data, explain the nature of molecular clocks and the fossil record, and strive to develop compromise models that incorporate contradictory opinions. These are presented as a series of case studies dealing with many of the most important groups of complex organisms, such as protists, land plants, flowering plants, complex animals, chordates, vertebrates, tetrapods, and modern birds. Bringing fresh insight and various perspectives to a complicated argument, this book assembles all sides of the debate into one comprehensive text. It is a significant volume for research scientists and advanced students across the field of evolutionary biology.

Charles Darwin's On the Origin of Species By Means of Natural Selection is both a key scientific work of research, still read by scientists, and a readable narrative that has had a cultural impact unmatched by any other scientific text. First published in 1859, it has continued to sell, to be reviewed and discussed, attacked and defended. The Origin is one of those books whose controversial reputation ensures that many who have never read it nevertheless have an opinion about it. Jim Endersby's major scholarly edition debunks some of the myths that surround Darwin's book, while providing a detailed examination of the contexts within which it was originally written, published and read. Endersby provides a very readable introduction to this classic text and a level of scholarly apparatus (explanatory notes, bibliography and appendixes) that is unmatched by any other edition.

Paris at the time of the French Revolution was the world capital of science. Its scholars laid the foundations of today's physics, chemistry and biology. They were true revolutionaries: agents of an upheaval both of understanding and of politics. Many had an astonishing breadth of talents. The Minister of Finance just before the upheaval did research on crystals and the spread of animal disease. After it, Paris's first mayor was an astronomer, the general who fought off invaders was a mathematician while Marat, a major figure in the Terror, saw himself as a leading physicist. Paris in the century around 1789 saw the first lightning conductor, the first flight, the first estimate of the speed of light and the invention of the tin can and the stethoscope. The metre replaced the yard and the theory of evolution came into being. The city was saturated in science and many of its monuments still are. The Eiffel Tower, built to celebrate the Revolution's centennial, saw the world's first wind-tunnel and first radio message, and first observation of cosmic rays. Perhaps the greatest Revolutionary scientist of all, Antoine Lavoisier, founded modern chemistry and physiology, transformed French farming, and much improved gunpowder manufacture. His political activities brought him a fortune, but in the end led to his execution. The judge who sentenced him - and many other researchers - claimed that 'the Revolution has no need for geniuses'. In this enthralling and timely book Steve Jones shows how wrong this was and takes a sideways look at Paris, its history, and its science, to give a dazzling new insight into the City of Light.

The extended continental South American turtle record (Norian to Lujanian) allows us to follow the evolution of this reptile clade from its origins. Several significant stem turtle taxa such as: Palaeochersis talampayensis and Condorchelys antiqua provide information on the first steps of turtle evolution. Others such as: Chubutemys copelloi or Patagoniaemys gasparinae provide clues to the origin of the bizarre horned tortoises of the clade Meiolaniidae. The panpleurodiran species such as Notoemys laticentralis or Notoemys zapatocaensis shed light on the origin of modern pleurodiran turtles. This book explores aquatic and terrestrial cryptodiran turtles, South Gondwana pleurodiran turtles, North Gondwana pleurodiran turtles; Meiolaniforms and early differentiation of Mesozoic turtles.

This book provides a series of comprehensive views on various important aspects of vertebrate photoreceptors. The vertebrate retina is a tissue that provides unique experimental advantages to neuroscientists. Photoreceptor neurons are abundant in this tissue and they are readily identifiable and easily isolated. These features make them an outstanding model for studying neuronal mechanisms of signal transduction, adaptation, synaptic transmission, development, differentiation, diseases and regeneration. Thanks to recent advances in genetic analysis, it also is possible to link biochemical and physiological investigations to understand the molecular mechanisms of vertebrate photoreceptors within a functioning retina in a living animal. Photoreceptors are the most deeply studied sensory receptor cells, but readers will find that many important questions remain. We still do not know how photoreceptors, visual pigments and their signaling pathways evolved, how they were generated and how they are maintained. This book will make clear what is known and what is not known. The chapters are selected from fields of studies that have contributed to a broad understanding of the birth, development, structure, function and death of photoreceptor neurons. The underlying common word in all of the chapters that is used to describe these mechanisms is "molecule". Only with this word can we understand how these highly specific neurons function and survive. It is challenging for even the foremost researchers to cover all aspects of the subject. Understanding photoreceptors from several different points of view that share a molecular perspective will provide readers with a useful interdisciplinary perspective.