Evolution is just a theory, isn't it? What is a scientific theory anyway? Don't scientists prove things? What is the difference between a fact, a hypothesis and a theory in science? How does scientific thinking differ from religious thinking? Why are most leading scientists atheists? Are science and religion compatible? Why are there so many different religious beliefs but only one science? What is the evidence for evolution? Why does evolution occur? If you are interested in any of these questions and have some knowledge of biology, this book is for you.

Directed Evolution Library Creation: Methods and Protocols, Second Edition presents user-friendly protocols for both proven strategies and cutting-edge approaches for the creation of mutant gene libraries for directed evolution. As well as experimental methods, information on current computational approaches is provided in a user-friendly format that will allow researchers to make informed choices without needing to comprehend the full technical details of each algorithm. Directed evolution has become a fundamental approach for engineering proteins to enhance activity and explore structure-function relationships, and has supported the rapid development of the field of synthetic biology over the last decade. Divided into three convenient sections, topics include point mutagenesis strategies, recombinatorial methods wherein genetic diversity is sourced from multiple parental genes that are combined via either homology-dependent or -independent techniques and a variety of computational methods to guide the design and analysis of mutant libraries. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Directed Evolution Library Creation: Methods and Protocols, Second Edition will serve as a reliable manual for both novice and experienced protein engineers and synthetic biologists and will enable further technical innovation and the exploitation of directed evolution for a deeper understanding of protein design and function.

This book develops and tests an ecological and evolutionary theory of the causes of human values—the core beliefs that guide people’s cognition and behavior—and their variation across time and space around the world. We call this theory the parasite-stress theory of values or the parasite-stress theory of sociality. The evidence we present in our book indicates that both a wide span of human affairs and major aspects of human cultural diversity can be understood in light of variable parasite (infectious disease) stress and the range of value systems evoked by variable parasite stress. The same evidence supports the hypothesis that people have psychological adaptations that function to adopt values dependent upon local infectious-disease adversity. The authors have identified key variables, variation in infectious disease adversity and in the core values it evokes, for understanding these topics and in novel and encompassing ways. Although the human species is the focus in the book, evidence presented in the book shows that the parasite-stress theory of sociality informs other topics in ecology and evolutionary biology such as variable family organization and speciation processes and biological diversity in general in non-human animals.

As a species, we are currently experiencing dramatic shifts in our lifestyle, family structure, health, and global contact. Evolutionary Anthropology provides a powerful theoretical framework to study such changes, revealing how current environments and legacies of past selection shape human diversity. This book is the first major review of the emerging field of Applied Evolutionary Anthropology bringing together the work of an international group of evolutionary scientists, addressing many of the major public health and social issues of this century. Through a series of case studies that span both rural and urban situations in Africa, Asia, Europe and South America, each chapter addresses topics such as natural resource management, health service delivery, population growth and the emergence of new family structures, dietary, and co-operative behaviours. The research presented identifies the great, largely untapped, potential that Applied Evolutionary Anthropology holds to guide the design, implementation and evaluation of effective social and public health policy. This book will be of interest to policy-makers and applied researchers, along with academics and students across the biological and social sciences.

Much of Charles Darwin's groundbreaking work as an evolutionary biologist stemmed from his study of birds. It is universally acknowledged that Darwin's observation of bird groups and species like the Galapagos finches, mockingbirds, and rock doves was critical to the development of his theories on natural selection, evolution, and sexual selection. The significant number of diverse birds that Darwin covered in his published works represents a most substantial ornithological contribution. His major books alone contain reference to and consideration of almost 500 bird species, as well as interesting and pertinent discussion of over 100 ornithological topics. "Charles Darwin's Birds" is a comprehensive treatment of Darwin's work as an ornithologist. Clifford Frith discusses every ornithological topic and bird species that Darwin researched, providing a complete historical survey of his published writing on birds. Through this, we learn how Darwin became an increasingly skilled and eventually exceptional ornithologist, and how his relationships grew with contemporary scientists like John Gould. It examines how Darwin was influenced by birds, and how the major themes of his research developed through his study of them. The book also features 4 appendices, which contain brief accounts of every bird species Darwin wrote about, basic ornithological information about each of the species, and a listing of where the species appears in Darwin's work.

Carina Klein examines the quality of the existing modern ammonoid zonation based on three methods, being Unitary Associations (UA), Constrained Optimization (CONOP) as well as Ranking and Scaling (RASC). The author sets out which of these three methods is best suitable to refine these zones. The results obtained are compared to each other with regard to ammonoid succession and resolution as well as with empirical data from selected reference sections. The analysis reveals that the UA and RASC methods are the most suitable since the results best mirror the empirical data from the single outcrops.

Bryophytes, which are important constituents of ecosystems globally and often dominate carbon and water dynamics at high latitudes and elevations, were also among the pioneers of terrestrial photosynthesis. Consequently, in addition to their present day ecological value, modern representatives of these groups contain the legacy of adaptations that led to the greening of Earth. This volume brings together experts on bryophyte photosynthesis whose research spans the genome and cell through whole plant and ecosystem function and combines that with historical perspectives on the role of algal, bryophyte and vascular plant ancestors on terrestrialization of the Earth. The eighteen well-illustrated chapters reveal unique physiological approaches to achieving carbon balance and dealing with environmental limitations and stresses that present an alternative, yet successful strategy for land plants.

The study of animal communication has led to significant progress in our general understanding of motor and sensory systems, evolution, and speciation. However, one often neglected aspect is that signal exchange in every modality is constrained by noise, be it in the transmission channel or in the nervous system. This book analyses whether and how animals can cope with such constraints, and explores the implications that noise has for our understanding of animal communication. It is written by leading biologists working on different taxa including insects, fish, amphibians, lizards, birds, and mammals. In addition to this broad taxonomic approach, the chapters also cover a wide array of research disciplines: from the mechanisms of signal production and perception, to the behavioural ecology of signalling, the evolution of animal communication, and conservation issues. This volume promotes the integration of the knowledge gained by the diverse approaches to the study of animal communication and, at the same time, highlights particularly interesting fields of current and future research.

This volume is part of the definitive edition of letters written by and to Charles Darwin, the most celebrated naturalist of the nineteenth century. Notes and appendixes put these fascinating and wide-ranging letters in context, making the letters accessible to both scholars and general readers. Darwin depended on correspondence to collect data from all over the world, and to discuss his emerging ideas with scientific colleagues, many of whom he never met in person. The letters are published chronologically: Volume 21 includes letters from 1873, the year in which Darwin received responses to his work on human and animal expression. Also in this year, Darwin continued his work on carnivorous plants and plant movement, finding unexpected similarities between the plant and animal kingdoms, raised a subscription for his friend Thomas Henry Huxley, and decided to employ a scientific secretary for the first time - his son Francis.

How did the zebra really get its stripes, and the giraffe its long neck? What is the science behind camel humps, leopard spots, and other animal oddities? Such questions have fascinated us for centuries, but the expanding field of evo-devo (evolutionary developmental biology) is now providing, for the first time, a wealth of insights and answers. Taking inspiration from Kipling's 'Just So Stories', this book weaves emerging insights from evo-devo into a narrative that provides startling explanations for the origin and evolution of traits across the animal kingdom. Held's unique and engaging style makes this narrative both enlightening and entertaining, guiding students and researchers through even complex concepts and encouraging a fuller understanding of the latest developments in the field. The first five chapters cover the first bilaterally symmetric animals, flies, butterflies, snakes, and cheetahs. A final chapter surveys recent results about a menagerie of other animals.

Astronomer Peter Linde takes the reader through the story of the search for extraterrestrial life in a captivating and thought-provoking way, specifically addressing the new research that is currently devoted towards discovering other planets with life. He discusses the methods used to detect possible signals from other civilizations and the ways that the space sciences are changing as a result of this new field. "Are we alone?" is a mystery that has forever fascinated mankind, gaining momentum by scientists since the 1995 discovery of the existence of exoplanets began to inspire new ways of thinking in astronomy. Here, Linde tries to answer many philosophical questions that derive from this area of research: Is humanity facing a change of paradigm, that we are not unique as intelligent beings? Is it possible to communicate with others out there, and even if we can-should we?

Originally published in 1933, this book is a culmination of a lifetime of research by Hans Friedrich Gadow into the evolution of the vertebrae. Gadow outlines the various forms of vertebral development as a guide to larger and more general questions on the morphological scheme of the evolution of vertebrate creatures, and uses plentiful diagrams, photographs and reconstructions to trace spinal development. This book will be of value to anyone with an interest in the history of science.

In this worldwide survey, Clive Gamble explores the evolution of the human imagination, without which we would not have become a global species. He sets out to determine the cognitive and social basis for our imaginative capacity and traces the evidence back into deep human history. He argues that it was the imaginative ability to 'go beyond' and to create societies where people lived apart yet stayed in touch that made us such effective world settlers. To make his case Gamble brings together information from a wide range of disciplines: psychology, cognitive science, archaeology, palaeoanthropology, archaeogenetics, geography, quaternary science and anthropology. He presents a novel deep history that combines the archaeological evidence for fossil hominins with the selective forces of Pleistocene climate change, engages with the archaeogeneticists' models for population dispersal and displacement, and ends with the Europeans' rediscovery of the deep history settlement of the Earth.

Evolution has, ever since its inception, been one of the most ideologically fraught fields in all of science. It has given birth to the myth about biological racial "types," with distinct rankings of "genetic superiority". Evolution has always been mistrusted by religious fundamentalists, contributing to a rise in creationist education that dovetails with the mass scientific illiteracy we see today. And today the coronavirus is mutating into ever more dangerous strands because huge swaths of the population have rejected the science that predicted this outcome if people remained unvaccinated. With so much fear and misunderstanding, it is crucial to set the record straight. Enter evolutionary biologist Joseph Graves. In A Voice in the Wilderness, he makes the case that widespread understanding of evolution is crucial to solving all these problems. Graves shows how the science of evolution can lead us to new paths of achieving social unity. He refutes common, pseudoscientific misconceptions that undergird racism, homophobia, sexism, classism, and more-all issues on which many perceive evolutionary biology to be a reactionary force. He shows how evolution can either make pandemics better, or-if its lessons are unheeded-worse. And he tackles the political and religious objections to the study of evolution as well. Graves' own experience powers much of the narrative. As a pioneering Black biologist, a leftist, and a Christian, Graves uses his personal story from a child of the Jim Crow south to a major researcher leader in his field to rewrite his field-and show how it can be a force not for reaction, but for justice. Provocative and timely, A Voice in the Wilderness is at once a powerful work of scientific antiracism and a moving history of a trailblazing life.

This volume handles in various perspectives the concept of function and the nature of functional explanations, topics much discussed since two major and conflicting accounts have been raised by Larry Wright and Robert Cummins' papers in the 1970s. Here, both Wright's 'etiological theory of functions' and Cummins' 'systemic' conception of functions are refined and elaborated in the light of current scientific practice, with papers showing how the 'etiological' theory faces several objections and may in reply be revisited, while its counterpart became ever more sophisticated, as researchers discovered fresh applications for it. Relying on a firm knowledge of the original positions and debates, this volume presents cutting-edge research evincing the complexities that today pertain in function theory in various sciences. Alongside original papers from authors central to the controversy, work by emerging researchers taking novel perspectives will add to the potential avenues to be followed in the future. Not only does the book adopt no a priori assumptions about the scope of functional explanations, it also incorporates material from several very different scientific domains, e.g. neurosciences, ecology, or technology. In general, functions are implemented in mechanisms; and functional explanations in biology have often an essential relation with natural selection. These two basic claims set the stage for this book's coverage of investigations concerning both 'functional' explanations, and the 'metaphysics' of functions. It casts new light on these claims, by testing them through their confrontation with scientific developments in biology, psychology, and recent developments concerning the metaphysics of realization. Rather than debating a single theory of functions, this book presents the richness of philosophical issues raised by functional discourse throughout the various sciences.

Friedrich Nietzsche's complex connection to Charles Darwin has been much explored, and both scholarly and popular opinions have tended to assume a convergence in their thinking. In this study, Dirk Johnson challenges that assumption and takes seriously Nietzsche's own explicitly stated 'anti-Darwinism'. He argues for the importance of Darwin for the development of Nietzsche's philosophy, but he places emphasis on the antagonistic character of their relationship and suggests that Nietzsche's mature critique against Darwin represents the key to understanding his broader (anti-)Darwinian position. He also offers an original reinterpretation of the Genealogy of Morals, a text long considered sympathetic to Darwinian naturalism, but which he argues should be taken as Nietzsche's most sophisticated critique of both Darwin and his followers. His book will appeal to all who are interested in the philosophy of Nietzsche and its cultural context.

Since their discovery in 1869, the dictyostelids have attracted the attention of scientists in a wide variety of fields. This interest has stemmed from their peculiar lifestyle and developmental properties, which were shaped by the evolutionary forces that generated multicellularity during eukaryotic evolution. More recently, the dictyostelids have gained attention due to the striking similarities found at the genomic, cellular and biochemical levels with human cells, which has propelled the species Dictyostelium discoideum to become a model system for biology and medicine in many laboratories. This book covers the latest advances in our knowledge of these extraordinary organisms with topics spanning from their evolutionary history, ecology and diversity to the recent discoveries regarding their cellular and molecular biology.

The annual Evolutionary Biology Meetings in Marseilles serve to gather leading scientists, promote the exchange of ideas and encourage the formation of international collaborations. This book contains the most essential contributions presented at the 14th Evolutionary Biology Meeting, which took place in September 2010. It comprises 19 chapters organized according to the following categories: * Evolutionary Biology Concepts * Biodiversity and Evolution * Macroevolution * Genome Evolution Offering an up-to-date overview of recent results in the field of evolutionary biology, this book is an invaluable source of information for scientists, teachers and advanced students.

Jacques Ninio addresses molecular biology from the evolutionist's viewpoint, reviewing major research areas such as acquisitive evolution; the comparison of protein structures in three dimensions; the stability of the genetic code; and prebiotic replication. Originally published in 1983. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

In recent years, progress in fish biology has advanced at an unprecedented rate and has led to many breakthroughs in the field. This book provides a wealth of information on the strategies that fish adopt with respect to waters with markedly different physical and chemical characteristics. It shows how their physiology, behaviour and lifestyles are adapted to exploit particular niches and gives comprehensive insight into fish life under extreme conditions. The readers are introduced to the ways in which fish exemplify many phenomena of general biological interest - the existence of competitors, chaos, and predator-prey interaction. Fish pathology as well as the components of the immune system are addressed. In this book, original and at times controversial views are presented, areas which have so far received inadequate attention are highlighted and avenues for further research are suggested.

This volume integrates the latest findings on earliest life forms, identified and characterised in some of the oldest rocks on Earth. New material from prominent researchers in the field is presented and evaluated in the context of previous work. Emphasis is placed on the integration of analytical methods with observational techniques and experimental simulations. The opening section focuses on submarine hot springs that the majority of researchers postulates served as the cradle of life on Earth. In subsequent sections, evidence for life in strongly metamorphosed rocks such as those in Greenland is evaluated and early ecosystems identified in the well preserved Barberton and Pilbara successions in Southern Africa and Western Australia. The final section includes a number of contributions from authors with alternate perspectives on the evidence and record of early life on Earth. Audience This volume will be valuable to researchers and graduate students in biogeosciences, geochemistry, paleontology and geology interested in the origin of life on earth.

Animals perform many athletic tasks to an amazing degree of accomplishment: not only spectacular feats of running and jumping but also routine actions that ensure survival such as feeding, vocalization, diving, flying, and many more. The study of performance capacity (defined as the ability of an animal to conduct a key task) is of great interest to both ecologists and evolutionary biologists. At an ecological level, how well individuals perform often dictates opportunities for reproduction, occupation of preferred territories, or capturing prey. Therefore, variation in performance capacities can be a key determinant of variation in fitness within animal populations. At an evolutionary level, variation in function often follows closely from variation in form, and therefore enables animals to invade novel habitats, or to overtake other species. This novel book examines how and why animal athletes have evolved. It uses examples from across the animal kingdom and integrates them in the broader context of ecology and evolution, thereby identifying common themes that transcend taxonomic divisions. Animal Athletes is an accessible textbook of particular relevance to undergraduates, graduate students, researchers, and professionals in the fields of evolutionary biology, ecology, vertebrate morphology, and functional morphology, and will also appeal to the interested layperson.

Hopefully, this book will be taken off of the shelf frequently to be studied carefully over many years. More than 40 researchers were involved in this project, which examines respiration, circulation, and metabolism from ?sh to the land vertebrates, including human beings. A breathable and stable atmosphere ?rst appeared about 500 million years ago. Oxygen levels are not stable in aquatic environments and exclusively water-breathing ?sh must still cope with the ever-changing levels of O 2 and with large temperature changes. This is re?ected in their sophisticated count- current systems, with high O extraction and internal and external O receptors. 2 2 The conquest for the terrestrial environment took place in the late Devonian period (355-359 million years ago), and recent discoveries portray the gradual transitional evolution of land vertebrates. The oxygen-rich and relatively stable atmospheric conditionsimpliedthatoxygen-sensingmechanismswererelativelysimpleandl- gain compared with acid-base regulation. Recently, physiology has expanded into related ?elds such as biochemistry, molecular biology, morphology and anatomy. In the light of the work in these ?elds, the introduction of DNA-based cladograms, which can be used to evaluate the likelihood of land vertebrates and lung?sh as a sister group, could explain why their cardio-respiratory control systems are similar. The diffusing capacity of a duck lung is 40 times higher than that of a toad or lung?sh. Certainly, some animals have evolved to rich high-performance levels.

Sometimes referred to as 'the grand old man of science', Alfred Russel Wallace (1823-1913) was a naturalist, evolutionary theorist, and friend of Charles Darwin. In this study of tropical flora and fauna, he takes the reader on a tour of the equatorial forest belt - the almost continuous band of forest that stretches around the world between the tropics. There, chameleon-like caterpillars alter the colours of their cocoons, parasitical trees override their hosts with spectacular aerial root systems, and some of the most pressing questions of Victorian evolutionary science arise: how do animals and plants come to be brightly coloured? Can their adaptations provide clues about past geological eras? And was Darwin wholly correct in his theory of sexual selection? First published in 1878, Wallace's book is a skilfully written reflection of contemporary naturalism, still highly readable and relevant to students in the history of science.

Jean Octave Edmond Perrier was a French zoologist who lived through the tumult of British Darwinism and Lyellism, and reminds us in this revealing account that French scientists had much to contribute to such perennial topics as evolution, catastrophism and creationism. While very much a product of the Third Republic, Perrier's account also aimed to outline timeless issues and permanent advances in taxonomic and developmental biology since classical Greece and Rome. In this aim he succeeds with surprisingly modern perspectives for a book first published in 1884. Perrier was born May 9, 1844 at Tulle, the son of the principal of a school which now bears his name, Lycee Edmond Perrier. In 1864 he was accepted to the Ecole Normale Superieure, where he was strongly influenced by Louis Pasteur and Henri de Lacaze-Duthiers. After working for three years at a high school in Agen, he obtained a post of naturalist-aid at the Museum National d'Histoire Naturelle (1868), advancing in that institution to Chair of Natural History of Molluscs, Worms and Corals (1876-1903) and then Director of the museum (1900-1919) and Chair of Comparative Anatomy (1903-1921). Previous directors of the museum included many of the scientists he discusses in this book: George Cuvier (1822-1823, 1826-1827, 1830-1831), Isidore Geoffrey St Hilaire (1860- 1861), and Alphonse Milne-Edwards (1891-1900). Perrier's own research on echinoderms and earthworms took him on several expeditions in 1880-1885, mostly to Atlantic and Mediterranean coasts, but also to the Caribbean.