How can new understandings about cancer cell interactions help doctors better control, and eventually cure, cancer? Cancer is a formidable enemy. In fact, people born in America since 1960 face a one in two chance of being diagnosed with cancer in their lifetimes. However, there's growing evidence that fewer cancers will be death sentences for patients. New approaches and understandings are transforming the medical world, increasing success rates for remissions, disease management, and cures. Dr. Ashani Weeraratna is at the forefront of this new level of care. In Is Cancer Inevitable?, Weeraratna-a pioneering melanoma researcher whose work explores the role aging plays in cancer cells' spread and drug resistance-gives readers an inside look at several of the latest cancer advances. Detailing the actions that are reducing the disease's impact and exploring what the future may hold, she explains how the molecular mechanisms involved in metastasis and the cells' microenvironments influence cancer's development and progression. Over the years, she writes, our understanding of how cancer cells move throughout the body, change as they plant themselves in the body's microenvironments, and even communicate with one another have led to major insights about how cancer works. With compelling detail, she takes us inside her lab, revealing how new insights are leading to major breakthroughs, even among patients with Stage IV cancer. She also explains how age-related changes in the microenvironment contribute to multiple aspects of melanoma formation and development. Such scholarship, she argues, is moving us toward a day when more patients will be declared cancer-free. An inspiring and deeply personal book, Is Cancer Inevitable? offers readers newfound hope. Features * Explores key insights and studies developed in recent years that have greatly influenced the world of cancer research, including how aging microenvironments within our bodies encourage metastasis and therapy resistance * Guides readers through Dr. Ashani Weeraratna's personal story of coming to the United States from Lesotho at the age of 17 and rising to become one of the pioneers in her field * Brings readers inside Weeraratna's lab, describing both the processes and the missions of her work * Raises awareness about how cancer works within the body and what any patient or family encountering the disease needs to understand-while also offering them hope based on new and forthcoming diagnostic and treatment methods * Outlines why we will never control-let alone cure-cancer if we don't find a common purpose and come together in collaboration, inviting the greatest minds from around the world to participate in finding and implementing solutions Johns Hopkins Wavelengths In classrooms, field stations, and laboratories in Baltimore and around the world, the Bloomberg Distinguished Professors of Johns Hopkins University are opening the boundaries of our understanding of many of the world's most complex challenges. The Johns Hopkins Wavelengths book series brings readers inside their stories, illustrating how their pioneering discoveries benefit people in their neighborhoods and across the globe in artificial intelligence, cancer research, food systems' environmental impacts, health equity, science diplomacy, and other critical arenas of study. Through these compelling narratives, their insights will spark conversations from dorm rooms to dining rooms to boardrooms.

Investigative reporter Brian Deer exposes a conspiracy of fraud and betrayal behind attacks on a mainstay of medicine: vaccinations. 2021 IPPY Book Award Winner (Gold) in Health/Medicine/Nutrition, Recipient of the Eric Hoffer Award for Nonfiction in the Culture Category. From San Francisco to Shanghai, from Vancouver to Venice, controversy over vaccines is erupting around the globe. Fear is spreading. Banished diseases have returned. And a militant "anti-vax" movement has surfaced to campaign against children's shots. But why? In The Doctor Who Fooled the World, award-winning investigative reporter Brian Deer exposes the truth behind the crisis. Writing with the page-turning tension of a detective story, he unmasks the players and unearths the facts. Where it began. Who was responsible. How they pulled it off. Who paid. At the heart of this dark narrative is the rise of the so-called "father of the anti-vaccine movement": a British-born doctor, Andrew Wakefield. Banned from medicine, thanks to Deer's discoveries, he fled to the United States to pursue his ambitions, and now claims to be winning a "war." In an epic investigation spread across fifteen years, Deer battles medical secrecy and insider cover-ups, smear campaigns and gagging lawsuits, to uncover rigged research and moneymaking schemes, the heartbreaking plight of families struggling with disability, and the scientific scandal of our time.

The ACA at 10 marks the tenth anniversary of the Affordable Care Act with essays from prominent analysts of US health policy and politics. Its contributors, an interdisciplinary roster of scholars, policymakers, and health policy researchers, explore critical issues and themes in the ACA's evolution. Topics include the role of race in US health politics, the ACA's surprising economic impacts, the history of ACA litigation and its implications for future health reform, the paradoxes of post-ACA Medicaid, shifting directions in public opinion, and much more. Offering a comprehensive accounting of the signal event in US health policy of the last half-century, this issue constitute a landmark contribution to the health politics literature. Contributors. Daniel Beland, Linda Blumberg, Andrea Louise Campbell, Sherry Glied, Sarah Gordon, Scott Greer, Colleen Grogan, Michael Gusmano, Allison Hoffman, Jon Holahan, Nicole Huberfeld, Lawrence Jacobs, Holly Jarman, David Jones, Timothy Stolzfus Jost, Katie Keith, Aryana Khalid, Larry Levitt, John McDonough, Stacey McMorrow, Suzanne Mettler, Jamila Michener, Jonathan Oberlander, Mark Peterson, Philip Rocco, Marilyn Tavenner, Frank Thompson, Carolyn Hughes Tuohy, Alex Waddan

Advances in Virus Research, Volume 111, the latest release in a serial that highlights new advances in the field, presents interesting and timely chapters authored by an international board of subject matter experts.

The ACA at 10 marks the tenth anniversary of the Affordable Care Act with essays from prominent analysts of US health policy and politics. Its contributors, an interdisciplinary roster of scholars, policymakers, and health policy researchers, explore critical issues and themes in the ACA&'s evolution. Topics include the role of race in US health politics, the ACA's surprising economic impacts, the history of ACA litigation and its implications for future health reform, the paradoxes of post-ACA Medicaid, shifting directions in public opinion, and much more. Offering a comprehensive accounting of the signal event in US health policy of the last half-century, this issue constitute a landmark contribution to the health politics literature. Contributors. John Benson, Robert Blendon, Lawrence Brown, Marc Cohen, Mary Findling, Erika Franklin Fowler, Austin Frakt, Anuj Gangopadhyaya, Bowen Garrett, Sarah Gollust, Simon Haeder, Paula Lantz, Adrianna McIntyre, Edward Miller, James Morone, Pamela Nadash, Jeff Niederdeppe, Sayeh Nikpay, Jonathan Oberlander, Eric Patashnik, India Pungarcher, Sara Rosenbaum, Eric Schneider, Michael Sparer, Joseph White, Susan Webb Yackee

Water containing significant amounts of inorganic and organic contaminants can have serious environmental consequences and serious health implications when ingested. Contamination of Water: Health Risk Assessment and Treatment Strategies takes an interconnected look at the various pollutants, the source of contamination, the effects of contamination on aquatic ecosystems and human health, and what the potential mitigation strategies are. This book is organized into three sections. The first section examines the sources of potential contamination. This includes considering the current scenario of heavy metal and pesticide contamination in water as well as the regions impacted due to industrialization, mining, or urbanization. The second section goes on to discuss water contamination and health risks caused by toxic elements, radiological contaminants, microplastics and nanoparticles, and pharmaceutical and personal care products. This book concludes with a section exploring efficient low-cost treatment technologies and remediation strategies that remove toxic pollutants from water. Contamination of Water incorporates both theoretical and practical information that will be useful for researchers, professors, graduate students, and professionals working on water contamination, environmental and health impacts, and the management and treatment of water resources.

Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

A global health crisis creates great uncertainty, high stress, and anxiety within society. During such a crisis, when information is unavailable or inconsistent, and when people feel unsure of what they know or what anyone knows, behavioral science indicates an increased human desire for transparency, direction, and meaning of what has happened. At such a time, the roles of stakeholders that emerge with their words and actions can help keep people safe, help them cope with emotions, and ultimately bring their experience into context leading to meaningful results. But as this crisis shifts beyond public health and workplace safety, there are implications for business continuity, job loss, and radically different ways of working. While some may already seek meaning from the crisis and move towards the ""next normal,"" others feel a growing uncertainty and are worried about the future. Therefore, it is important to analyze the role of stakeholders during these uncertain times. Stakeholder Strategies for Reducing the Impact of Global Health Crises provides a comprehensive resource on stakeholder action and strategies to deal with crises by analyzing the needs of society during global health crises, how stakeholders should communicate, and how resilience and peace can be promoted in times of chaos. The chapters cover the roles of stakeholders during a pandemic spanning from the government and international development agencies to industry and non-government organizations, community-based organizations, and more. This book not only highlights the responsibilities of each of the stakeholders but also showcases the best practices seen during the COVID-19 pandemic through existing theories and case studies. This book is intended for researchers in the fields of sociology, political science, public administration, mass media and communication, crisis and disaster management, and more, along with government officials, policymakers, medical agencies, executives, managers, medical professionals, practitioners, stakeholders, academicians, and students interested in the role of stakeholders during global health crises.

A Mohawk Memoir from the War of 1812 presents the story of John Norton, or Teyoninhokarawen, an important war chief and political figure among the Grand River Haudenosaunee (or Iroquois) in Upper Canada. Norton saw more action during the conflict than almost anyone else, being present at the fall of Detroit; the capture of Fort Niagara; the battles of Queenston Heights, Fort George, Stoney Creek, Chippawa, and Lundy's Lane; the blockades of Fort George and Fort Erie; and a large number of skirmishes and front-line patrols. His memoir describes the fighting, the stresses suffered by indigenous peoples, and the complex relationships between the Haudenosaunee and both their British allies and other First Nations communities. Norton's account, written in 1815 and 1816, provides nearly one-third of the book's content, with the remainder consisting of Carl Benn's introductions and annotations, which enable readers to understand Norton's fascinating autobiography within its historical contexts. With the assistance of modern scholarship, A Mohawk Memoir presents an exceptional opportunity to explore the War of 1812 and native-newcomer issues not only through Teyoninhokarawen's Mohawk perspective but in his own words.

How a coalition of Black health professions schools made health equity a national issue. Racism in the US health care system has been deliberately undermining Black health care professionals and exacerbating health disparities among Black Americans for centuries. These health disparities only became a mainstream issue on the agenda of US health leaders and policy makers because a group of health professions schools at Historically Black Colleges and Universities banded together to fight for health equity. We'll Fight It Out Here tells the story of how the Association of Minority Health Professions Schools (AMHPS) was founded by this coalition and the hard-won influence it built in American politics and health care. David Chanoff and Louis W. Sullivan, former secretary of health & human services, detail how the struggle for equity has been fought in the field of health care, where bias and disparities continue to be volatile national issues. Chanoff and Sullivan outline the history of Black health care, from pre-Emancipation to today, centering on the work of AMHPS, which brought to light health care inequities in 1983 and precipitated virtually all minority health care legislation since then. Based on extensive research in the literature, as well as more than seventy interviews with the people central to this fight for legislative and policy change, We'll Fight It Out Here is the important story of a vital coalition movement, virtually unknown until now, that changed the national understanding of health inequities. The work of this coalition of Black health schools continues, both in supporting the training of more doctors and health professionals from minority backgrounds and in advancing issues related to health equity. By highlighting these endeavors, We'll Fight It Out Here brings attention to a pivotal group in the history of the health equity movement and provides a road map of practical mechanisms that can be used to advance it.

A devastating, empathetic look at the opioid epidemic in the United States, through the eyes of a paramedic on the front lines. [I] set my cardiac monitor down by the young man's head. He is lifeless, his face white with a blue tinge. I apply the defibrillator pads to his hairless chest . . . A week from today, after the young man's brain shows no signs of electrical activity, the medical staff will take the breathing tube out, and with his family gathered by his side, he will pass away at the age of twenty-three. When Peter Canning started work as a paramedic on the streets of Hartford, Connecticut, twenty-five years ago, he believed drug users were victims only of their own character flaws. Although he took care of them, he did not care for them. But as the overdoses escalated, Canning began asking his patients how they had gotten started on their perilous journeys. And while no two tales were the same, their heartrending similarities changed Canning's view and moved him to educate himself about the science of addiction. Armed with that understanding, he began his fight against the stigmatization of users. In Killing Season, we ride along with Canning through the streets of Hartford as he tells stories of opioid overdose from a street-level vantage point. A first responder to hundreds of overdoses throughout the rise of America's epidemic, Canning has seen the impact of prescription painkillers, heroin, and the deadly synthetic opioid fentanyl firsthand. Bringing us into the room (or the car, or the portable toilet) with the victims of this epidemic, Canning explains how he came to favor harm reduction, which advocates for needle exchange, community naloxone, and safe-injection sites. Through the rapid-fire nature of one paramedic's view of addiction and overdose, readers will come to understand more than just the science and misguided policies behind the opioid epidemic. They'll also share in Canning's developing empathy. Stripping away the stigma of addiction through stories that are hard-hitting, poignant, sad, confessional, funny, and overall, human, Killing Season will change minds about the epidemic, help obliterate stigma, and save lives.