The major progress in computer vision allows us to make extensive use of medical imaging data to provide us better diagnosis, treatment and predication of diseases. Computer vision can exploit texture, shape, contour and prior knowledge along with contextual information from image sequence and provide 3D and 4D information that helps with better human understanding. Many powerful tools have been available through image segmentation, machine learning, pattern classification, tracking, reconstruction to bring much needed quantitative information not easily available by trained human specialists. The aim of the book is for both medical imaging professionals to acquire and interpret the data, and computer vision professionals to provide enhanced medical information by using computer vision techniques. The final objective is to benefit the patients without adding to the already high medical costs.

The expanded and revised edition will split Chapter 4 to include more details and examples in FMRI, DTI, and DWI for MR image modalities. The book will also expand ultrasound imaging to 3-D dynamic contrast ultrasound imaging in a separate chapter.

A new chapter on Optical Imaging Modalities elaborating microscopy, confocal microscopy, endoscopy, optical coherent tomography, fluorescence and molecular imaging will be added. Another new chapter on Simultaneous Multi-Modality Medical Imaging including CT-SPECT and CT-PET will also be added. In the image analysis part, chapters on image reconstructions and visualizations will be significantly enhanced to include, respectively, 3-D fast statistical estimation based reconstruction methods, and 3-D image fusion and visualization overlaying multi-modality imaging and information. A new chapter on Computer-Aided Diagnosis and image guided surgery, and surgical and therapeutic intervention will also be added.

A companion site containing power point slides, author biography, corrections to the first edition and images from the text can be found here: ftp: //ftp.wiley.com/public/sci_tech_med/medical_image/

Send an email to: [email protected] to obtain a solutions manual. Please include your affiliation in your email.

A step-by-step guide to performing image-guided breast interventions Written by a team of experts, this practical how-to guide provides a systematic overview of the most current image-guided interventional techniques used to diagnose breast abnormalities. In the first part of the book, the authors discuss how to acquire tissue samples using minimally invasive procedures such as ultrasound-, x-ray-, and MRI-based interventions, and present information on pretherapeutic localization and classification of lesions. The second part of the book covers the essentials of fine-needle aspiration and cytologic assessment, followed by a chapter on histologic evaluation and up-to-date pathology reporting categories for core and vacuum biopsy specimens. Features: 1,295 high-quality clinical images from the authors? daily practice illustrate radiographic findings and examination approaches More than 50 cases studies for self-assessment Separate chapters on patient preparation, instrumentation, galactography and ductoscopy, and sentinel node biopsy Color-coded text boxes highlight tips, tricks, pitfalls, checklists, and guidelines for rapid review of essential concepts Consistent chapter structure for maximum accessibility Interventional Breast Imaging is a must-have resource for all radiologists and gynecologists. It will improve the accuracy and confidence of any clinician involved in image-guided breast interventions.

Gastric adenocarcinoma is the second most common cancer worldwide. It is usually diagnosed at a late stage and prognosis is poor; even with modern diagnostic and treatment methods the 5-year survival is only 10%. Improvements in overall patient survival can only be achieved by earlier diagnosis and by tailored therapeutic strategies based on tumor type, location and stage at presentation. This volume provides a state-of-the-art, integrated diagnostic and therapeutic approach to patient management. The role of the upper GI series, endoscopy, endoscopic ultrasound, MDCT, MRI, and PET/CT in the diagnosis, staging and follow-up of patients with gastric cancer is emphasized. The relative strengths and limitations of these diagnostic examinations will be presented in context with the most recent epidemiologic, pathologic, and therapeutic concepts regarding this tumor. With expert contributions from members of an international multidisciplinary team, this is an invaluable guide to the diagnosis and management of gastric malignancies.

Electrical neuroimaging is based on the analysis of brain electrical activity recorded from the human scalp with multichannel EEG. It offers enormous potential for the dynamic mapping of brain functions, and for the non-invasive diagnosis of neurological and psychiatric conditions. This authoritative reference gives a systematic overview of new electrical imaging methods, with a sound introduction to the basics of multichannel recording of EEG and event-related potential (ERP) data, as well as spatio-temporal analysis of the potential fields. The book enables researchers to measure valid data, select and apply appropriate analysis strategies, and avoid the most common mistakes when analyzing and interpreting EEG/ERP data. Importantly, it informs the research communities of the possibilities opened by these space-domain oriented approaches to the analysis of brain electrical activity, and of their potential to offer even more powerful diagnostic techniques when integrated with other clinically relevant data.

Fetal Echocardiography is a comprehensive, lavishly illustrated guide to fetal heart scanning for anyone involved in obstetric ultrasound. Authored by a leading pediatric cardiologist with over 30 years of experience, it brings together all the information needed by cardiologists, obstetricians, sonographers or maternal-fetal medicine clinicians in order to obtain clear, high-quality echocardiograms and interpret them. Initial chapters provide the basic principles of echocardiography and how to obtain the standard views, giving numerous illustrations of each standard view and the possible deviations from normal. Subsequent chapters present a complete pictorial representation of almost all malformations recognised in fetal life. An overview of the likely outcome of each malformation is given, backed up by personal data involving nearly 4000 abnormal fetal hearts. Additional chapters cover Fetal Arrhythmias and Early Fetal Heart Scanning. Highly illustrated and full of practical guidance, Fetal Echocardiography is an invaluable resource for all practitioners involved in obstetric scanning.

Essential Medical Imaging is a concise introductory text covering the clinical role of radiology in adult and paediatric medicine and surgery. The emphasis is on placing radiology in a clinical context and guiding the reader to apply imaging modalities to specific clinical problems. An introductory section outlines the principles of image generation and image interpretation, as well as risks, benefits and costs. Subsequent sections review key clinical considerations and illustrate important radiology findings for each common clinical condition and patient population. A library of annotated normal radiological images and a terminology and abbreviations section are also included. A companion CD containing more detailed text and an extensive collection of clinical images accompanies the text. Highly visual and practical, Essential Medical Imaging is an invaluable resource for medical students, trainees in radiology, medicine & surgery, and for radiographers and all allied health professionals.

Prostate cancer is one of the most common malignancies in men in the Western world. Although a wide range of treatment regimens are available for this disease, there are few evidence-based guidelines for treatment selection. This volume describes the clinical value of imaging for improving not only staging and treatment selection, but also the diagnosis, treatment planning, and treatment follow-up for patients with prostate cancer.
A multidisciplinary disease management approach is critical in this disease. For the radiologist, understanding the pathophysiology, critical clinical issues, and advantages and limitations of different treatments is essential for meaningful interpretation of imaging studies. Similarly, for the practicing clinician, understanding the advantages and limitations of imaging modalities and the importance of optimal technique are crucial to the rational use of imaging. This volume serves as a valuable reference for radiologists, urologists, medical and radiation oncologists and all practitioners involved in the management of prostate cancer.

A truly interdisciplinary clinical text, Clinical Neuroradiology investigates the structure-function relationship for major CNS diseases, illustrated by considering actual clinical cases. Authored by a leading neuroradiologist, this landmark publication provides neuroradiologists with clinical neurological correlates and neurologists with imaging correlates for all key neurological conditions. Organised by brain region, each chapter contains an introductory section of clinically relevant neuroanatomy followed by a series of case studies giving: * Brief history and summary of findings * Differential diagnosis * Imaging findings, related to clinical deficits * Pertinent neuronal circuits, neurochemistry and neurogenetics * Basic therapeutic approaches to each syndrome Due to its utility in demonstrating structural-functional correlates, a separate chapter on stroke is included. Lavishly illustrated with images from all modalities and outstanding anatomical diagrams rendered in true radiographic (rather than 'upside-down' anatomic) orientation, Clinical Neuroradiology is an invaluable resource for everyone involved in the diagnosis and management of neurological disorders.

Through a case-based approach, this book illustrates the best practices for all facets of breast cancer imaging - from screening of asymptomatic patients to cancer staging, identifying metastases, and assessing efficacy of treatment - in a succinct, practical source. Contributing authors from a wide range of subspecialties provide well-rounded guidance to meet the needs of today's multidisciplinary work environment.

From "AB systems" to "Zipper artefact" - even for the experienced practitioner in MRI, the plethora of technical terms and acronyms can be daunting and bewildering. This concise but comprehensive guide provides an effective and practical introduction to the full range of this terminology. It will be an invaluable source of reference for all students, trainees and medical professionals working with MRI. More than 800 terms commonly encountered in MR Imaging and Spectroscopy are clearly defined, explained and cross-referenced. Illustrations are used to enhance and explain many of the definitions, and references to further reading will point the reader to more in-depth coverage. As well as being a compendium of terms from A to Z, the volume concludes with a useful collection of appendices, which tabulate many of the key constants, properties and equations of relevance.

The use of light for probing and imaging biomedical media is promising for the development of safe, noninvasive, and inexpensive clinical imaging modalities with diagnostic ability. The advent of ultrafast lasers has enabled applications of nonlinear optical processes, which allow deeper imaging in biological tissues with higher spatial resolution. This book provides an overview of emerging novel optical imaging techniques, Gaussian beam optics, light scattering, nonlinear optics, and nonlinear optical tomography of tissues and cells. It consists of pioneering works that employ different linear and nonlinear optical imaging techniques for deep tissue imaging, including the new applications of single- and multiphoton excitation fluorescence, Raman scattering, resonance Raman spectroscopy, second harmonic generation, stimulated Raman scattering gain and loss, coherent anti-Stokes Raman spectroscopy, and near-infrared and mid-infrared supercontinuum spectroscopy. The book is a comprehensive reference of emerging deep tissue imaging techniques for researchers and students working in various disciplines.

This third edition provides a concise and generously illustrated survey of the complete field of medical imaging and image computing, explaining the mathematical and physical principles and giving the reader a clear understanding of how images are obtained and interpreted. Medical imaging and image computing are rapidly evolving fields, and this edition has been updated with the latest developments in the field, as well as new images and animations. An introductory chapter on digital image processing is followed by chapters on the imaging modalities: radiography, CT, MRI, nuclear medicine and ultrasound. Each chapter covers the basic physics and interaction with tissue, the image reconstruction process, image quality aspects, modern equipment, clinical applications, and biological effects and safety issues. Subsequent chapters review image computing and visualization for diagnosis and treatment. Engineers, physicists and clinicians at all levels will find this new edition an invaluable aid in understanding the principles of imaging and their clinical applications.

There are few techniques that have influenced therapeutic strategies in modem cardiology to a similar extent as coronary arteriography. Bypass surgery as well as transluminal coronary angioplasty would not have been possible without coronary angiography serving as a 'midwife' in their evolu­ tion. Despite the widespread and long-standing use in clinical practice, however, the interpretation of coronary angiograms has not changed very much since the early days. Most angiogr~s are still reviewed in a visual and semi-quantitative and thus often very subjective way. In the face of an almost exploding field for interventional catheterization including thrombolysis, balloon dilatation, and other rapidly evolving techniques for transluminal revascularization or recanalization, a more detailed and quantitative analysis of coronary arteriograms is urgently required. In addition to the delineation of coronary morphology, we need dynamic and functional information about flow and perfusion to understand the physiological significance of anatomic abnormalities. Coronary arteriography contains and can provide most of this information. With the application of appropriate techniques, it can be made available in the catheterization laboratory even during the patient's investiga­ tion, thus facilitating and improving clinical decision making. Objective and reproducible analysis will furthermore enhance our understanding about the pathophysiology of coronary disease.

In the past, coronary arteriography was the only modality available to provide high quality images of the coronary anatomy. Quantitative coronary arteriography (QCA) was developed, implemented, validated and extensively applied to obtain accurate and reproducible data about coronary morphology and the functional significance of coronary obstructions. Over the last few years extensive basic technological research supported by clinical investigations has created competing modalities to visualize coronary morphology and the associated perfusion of the myocardial muscle. Currently, the following modalities are available: X-ray coronary arteriography, intracoronary ultrasound, contrast- and stress-echocardiography, angioscopy, nuclear cardiology, magnetic resonance imaging, and cine and spiral CT imaging. For all these imaging modalities, the application of dedicated quantitative analytical software packages enables the evaluation of the imaging studies in a more accurate, reliable, and reproducible manner. These extensions and achievements have resulted in improved diagnostics and subsequently in improved patient care. Particularly in patients with ischaemic heart disease, major progress has been made to detect coronary artery disease in an early phase of the disease process, to follow the atherosclerotic changes in the coronary arteries, to establish the functional and metabolic consequences of the luminal obstructions, and accurately to assess the results of interventional therapy. Aside from all these high-tech developments in cardiac imaging techniques, the transition from the analogue to the digital world has been going on for some time now. For the future, it has been predicted that the CD-R will be the exchange medium for cardiac images and DICOM-3 the standard file format. This has been a major achievement in the field of standardization activities. Since these developments will have a major impact on the way images will be stored, reviewed and exchanged in the near future, an important part of this book has been dedicated to DICOM and the filmless catheterization laboratory. Cardiovascular Imaging will assist cardiologists, radiologists, nuclear medicine physicians, image processing specialists, physicists, basic scientists, and fellows in training for these specialties to understand the most recent achievements in cardiac imaging techniques and their impact on cardiovascular medicine.

An overview of imaging modalities, PRINCIPLES OF RADIOGRAPHIC IMAGING: AN ART & A SCIENCE, 5th Edition delivers essential information on radiographic contrast, density, detail, and distortion, as well as the latest instrumentation and technology used in the imaging sciences. Building logically from the simplest concepts to the more complex, the book ties topics together visually and conceptually in a thorough presentation of radiographic exposure.

The book contains all the basic notions of Positron Emission Tomography that span from physiology to radiochemistry, physics, math and statistics. All material was carefully crafted and is now presented in graphical manner to ease reading, studying and browsing. It suits equally undergraduate and graduate academic students but it shall be of interest to clinical fellows or professionals in the biomedical sector that use PET in their activity or develop technologies in the area.

WHO and partners have been working towards devising an agenda, an action plan, tools and guidelines to increase access to appropriate medical devices. This document is part of a series of reference documents being developed for use at the country level. The series will include the following subject areas: * policy framework for health technology* medical device regulations* health technology assessment* health technology management* needs assessment of medical devices* medical device procurement* medical equipment donations* medical equipment inventory management* medical equipment maintenance* computerized maintenance management systems* medical device data* medical device nomenclature* medical devices by health-care setting* medical devices by clinical procedures* medical device innovation, research and development.These documents are intended for use by biomedical engineers, health managers, donors, nongovernmental organizations and academic institutions involved in health technology at the district, national, regional or global levels.Once established, the inventory serves as the foundation for moving forward within the HTM system and ensuring safe and effective medical equipment. The inventory may be used to develop budgets for capital purchases, maintenance and running costs; to build and support an effective clinical engineering department, by allowing for workshop planning, hiring and training of technical support staff, and establishing and maintaining service contracts; to support an effective medical equipment management program, such as planning preventive maintenance activities and tracking work orders; and to plan the stock of spare parts and consumables. The inventory may also be used to support equipment needs assessment within the health-care facility and to record the purchase, receipt, retirement and discarding of equipment. Facility risk analysis and mitigation, and emergency and disaster planning, are also supported by an inventory.

Perioperative echocardiography has come of age, as evidenced by separate examinations and certifications processes. Albeit a unique area within echocardiography, perioperative echocardiography is not only concerned with precise diagnosis (e.g. presence and severity of mitral regurgitation) but also with mechanisms of action (e.g. valve repair versus replacement) and in assessment of intervention (e.g. inadequacy of mitral valve repair). The echocardiographer is an integral member of the surgical, perfusion, anesthetic and nursing team, providing them with what is known and what is unknown. This highly-illustrated, case-oriented text provides the reader with 100 case presentations, peroperative/intraoperative echocardiographic features, echocardiographic-assisted decision-making for planned intervention, and postoperative echocardiographic assessment. The editors and contributors provide the reader with both common and rare cardiac problems so that the reader can perform a systematic TEE examination and apply the acquired data to intraoperative decision-making.

Atlas of Cardiovascular Computed Tomography is a comprehensive atlas containing photomicrographs, anatomic illustrations, tables, and charts paired with extensive legends and explanations that are supplemented by extensive research, peer-reviewed articles, and textbooks. In addition to providing historical perspective and current direction for computed tomography, this atlas focuses on research involving coronary artery diseases and anomalies, congestive heart failure, atherosclerotic plaques and asymptomatic disease, as well as imaging techniques, including preparation, acquisition, and processing, involving the great vessels and carotids, the peripheral vasculature, and coronary and pulmonary veins. There also will be discussion of the role of computed tomography in the emergency room and in private cardiology practice.

ECG: ESSENTIALS OF ELECTROCARDIOGRAPHY is designed to help you understand the fundamental knowledge and skills necessary to successfully perform an ECG. Its concise yet comprehensive coverage includes instruction on the anatomy of the heart, electrophysiology of the heart, and ECG basics. To prepare you for completing ECGs in the field, this student-friendly text presents a combination of introductory cardiovascular anatomy, relationships of other body systems to heart health, need-to-know legal and ethical considerations, patient assessment techniques, instructions on how to complete and document ECGs, and basic interpretation of the ECG tracing. "Call-outs" point out material you should memorize, while "Quick Checks" help you test your comprehension as your progress through the text. In addition, thorough coverage of objectives you must master to qualify to sit for the National Healthcareer Association's (NHA) EKG Technician Certification exam are included throughout.