Over the last two decades, there have been numerous exciting developments in the surgical field of articular cartilage repair. Magnetic resonance imaging plays a critical role in pre-operative surgical planning, through its ability to identify the extent and severity of cartilage lesions. It also plays an important role in post-operative management, by allowing surgeons to noninvasively monitor the morphological status of repaired cartilage tissue.This book covers recent advances in ultra high field MRI and biochemical MRI techniques such as T2 mapping, delayed gadolinium enhanced MRI of cartilage (dGEMRIC), gagCEST and sodium MRI. It is written by a multidisciplinary team including basic scientists, radiologists, orthopaedic surgeons and biomedical engineers. The volume is an ideal reference guide for musculoskeletal radiologists, basic research scientists, orthopedic surgeons and biomedical engineers etc.

Radiation therapy has developed and advanced dramatically in the last few decades. However, very little has been published or done in the area of biologically optimized treatment planning. Development of Biologically Optimized Radiation Therapy aims to fill and close an important gap in the literature with a well-focused and in-depth content. The book covers the biological, physical and clinical background of advanced biologically based radiation therapy optimization with focus on modern radiation therapy modalities such as electron, photon and light ion therapy. Highly recommended for its strong interdisciplinary profile, the book contains a meritorious compilation of previously unpublished materials in many areas of modern science. Undergraduates, researchers and practitioners such as oncologists, medical physicists and radiation biologists alike should find the book immensely informative and comprehensively thorough.

Core Concepts in Colonoscopy covers all aspects of diagnostic and therapeutic colonoscopy, emphasizing overarching concepts that gastroenterology fellows and physicians must know to achieve success in both the technical and cognitive aspects of the procedure. In this comprehensive resource, Dr. Douglas G. Adler and his contributors provides a straightforward and practical review of colonoscopy. Core Concepts in Colonoscopy aims to address and convey the core concepts of colonoscopy: from the structure and function of the colonoscope itself, to insertion techniques, loop formation and reduction, polypectomy techniques for any situation, the avoidance and management of perforations and other adverse events, as well as advanced techniques including (but not limited to) endoscopic mucosal resection and colonic stenting. Each chapter inside Core Concepts in Colonoscopy is lavishly illustrated with multiple key images to accentuate and enhance the written text, as well as a plethora of tips, tricks, and accumulated points of wisdom in each chapter on all facets of colonoscopy. Additional Website Component! Core Concepts in Colonoscopy is accompanied by a video website with specific videos connected to individual chapters that will illustrate basic and advanced colonoscopic techniques from many leading experts and will further enhance the learning process. The addition of the video website allows for a more robust learning experience and allows the reader to watch, listen, view repeatedly, and reinforces the techniques presented in the written text. GI fellows, junior gastroenterologists, and even advanced physicians will appreciate Core Concepts in Colonoscopy because of the user-friendly and efficient structure that allows for the material to be quickly read, as well as easily absorb the wealth of key practical knowledge found inside.

Get immediate access to crucial information about the most common EMG studies.

This handy, practical resource designed for quick reference at the point of care covers a wide spectrum of electrodiagnostic tests. Written for both novice and experienced electromyographers, this at-a-glance guide is concise enough to fit in a pocket, yet replete with essential technical detail, pearls, and clinical photos to illustrate proper study set-ups.

"Pocket EMG" covers what you need to know to successfully perform nerve conduction and needle EMG studies in a fast-paced clinical environment. It also includes helpful protocols for specific clinical problems.

The first section is devoted to nerve conduction studies and covers sensory and motor studies of the upper and lower extremities, late responses, and other tests including facial motor nerves, blink reflex, and repetitive nerve stimulation. Section two covers needle electromyography and catalogs set-ups for upper and lower extremity tests, paraspinals, and facial muscles. The final two sections contain study protocols for presenting chief complaints or suspected diagnoses, normal values, and high-yield tables and lists. Each test includes a photograph of the proper set-up, indications for performing the test, technical pointers, and physiological considerations.

Key Features:

Organized consistently and pocket-sized for quick reference in the EMG lab Includes a photo of the proper set-up for each test, indications for performing the test, and clinical pearls and pointers to enhance skills Contains study protocols for common complaints, normal value ranges for individual tests, and high-yield tables and lists

In this book the authors present current research in the study of endoscopy and endoscopic procedures. Topics discussed in this compilation include the videonasopharyngoscopy of the velopharyngeal sphincter during speech and swallowing; foetal airway endoscopy in ex utero intrapartum treatment (EXIT); and diagnostic and operative endoscopy in otorhinolaryngology.

Through 145 clinically-relevant cases, Musculoskeletal Imaging Cases covers the full spectrum of imaging for this field. Part of the Cases in Radiology series, this book follows the easy-to-learn case format of question and answer, complete with concise summaries and a generous amount of top-quality images. Pathologies addressed in the cases include: arthritis, bone and soft tissue tumors and tumor-like conditions, infection, trauma, internal derangement of joints, metabolic and hematologic disorders affecting the MSK system, bone marrow, infection, and pediatric problems. Within their sections, cases appear in a random order for the beneficial self-assessment experience of the reading cases as unknowns. Musculoskeletal Imaging Cases is ideal for the resident preparing for the boards, or the radiologist in need of a quick review.

Second-harmonic generation (SHG) microscopy has shown great promise for imaging live cells and tissues, with applications in basic science, medical research, and tissue engineering. Second Harmonic Generation Imaging offers a complete guide to this optical modality, from basic principles, instrumentation, methods, and image analysis to biomedical applications. The book features contributions by experts in second-harmonic imaging, including many pioneering researchers in the field. Written for researchers at all levels, it takes an in-depth look at the current state of the art and possibilities of SHG microscopy.

Organized into three sections, the book:

• Provides an introduction to the physics of the process, step-by-step instructions on how to build an SHG microscope, and comparisons with related imaging techniques
• Gives an overview of the capabilities of SHG microscopy for imaging tissues and cells including cell membranes, muscle, collagen in tissues, and microtubules in live cells by summarizing experimental and analytical methods
• Highlights representative biomedical and medical applications in imaging cancer, fibroses, autoimmune diseases, connective tissue disorders, eye pathologies, and cardiovascular disease

Historically, clinical imaging at the cellular and tissue level has been performed by pathologists on ex vivo biopsies removed by the surgeon. While histology remains the "gold standard" for pathologists, its interpretation remains highly subjective. Much of SHG research has focused on developing more quantitative, objective metrics. A tutorial for newcomers and an up-to-date review for experts, this book explores how SHG may be used to more precisely image a wide range of pathological conditions and diseases."

Featuring 150 cases and over 400 high-quality images, Pediatric Imaging Cases offers a complete survey of the field of pediatric radiology. Cases are formatted as questions and answers, allowing for self-assessment, complete with relevant radiologic findings, differential diagnoses, teaching points, further steps in management, and suggested further readings. Part of the Cases in Radiology series, this book offers a comprehensive overview of the clinical issues of pediatric radiology: cardiovascular system, gastrointestinal system, genitourinary system, spine, neuroradiology, chest and airway, and musculoskeletal system. Ideal for residents preparing for board exams as well as seasoned clinicians wishing to test their knowledge, Pediatric Imaging Cases provides a thorough investigation of the field.

This book covers all one needs to know about the utility of endomicroscopy in the diagnosis and management of gastrointestinal diseases. It provides a comprehensive description of the latest in diagnostic criteria and advances in the basic science pertaining to endomicroscopy of the gastrointestinal system. Each chapter introduces the key histologic, endoscopic, and endomicroscopic features of common gastrointestinal conditions, with generous illustration using typical images. The book will provide the practicing physicians with the principles of practice, and procedural techniques of endomicroscopy, as well as demonstrate the bench-to-bedside translational potential of endomicrosocpy in helping endoscopists manage their patients' gastrointestinal conditions. This book fills an enormous gap in providing a much needed atlas in GI endomicroscopic diagnosis. Readers can learn the diagnostic criteria of various gastrointestinal conditions as illustrated by high quality endoscopic, endomicroscopic and histology images. It contains the most extensive review of currently published studies of endomicroscopy in gastrointestinal conditions. It has numerous high quality endomicroscopic images along with high definition endoscopy and histology images illustrating the common gastrointestinal diseases. It will provide a platform for standardizing endomicroscopic practice and learning.

This important volume is the first to address the use of neuroimaging in civil and criminal forensic contexts and to include discussion of prior precedents and court decisions. Equally useful for practicing psychiatrists and psychologists, it reviews both the legal and ethical consideraitons of neuroimaging.

The book presents a clear and comprehensive review of the current status of the holographic microscopy with discussion of the positive and negative features of classical and holographic methods for solving the problem of three-dimesional (3D) imaging of phase microscopic objects. Classical and holographic methods of phase, interference and polarization contrast are discussed. Combination of the developed holographic methods with the methods of digital image processing allowed creating the digital holographic interference microscope (DHIM). The first 3D images of native phase microscopic objects such as blood cells were obtained using the DHIM. The results of DHIM application for study of blood erythrocytes, thin films, micro-crystals are presented.

Imaging in Parkinson's Disease provides up-to-date information concerning new applications of brain imaging to the study of Parkinson's disease. Written by experts in the field, the book focuses on structural and functional imaging methodologies that have recently been applied to study the natural history of Parkinson's disease, with emphasis on the development of the major motor manifestations of the illness as well as cognitive impairment and dementia. Individual chapters address the role of imaging in differential diagnosis and in the evaluation of pharmacologic and surgical treatment effects. In-depth discussion of the use of imaging tools to study disease mechanisms is also provided, with emphasis on the roles of neuroinflammation, protein aggregation, and abnormal network organization in parkinsonism. Additionally, the text covers a number of relevant novel topics including recent advances in volumetric and functional MRI, echosonography, dopaminergic and cholinergic neurotransmitter imaging, and applications to experimental interventions such as gene therapy and transplantation. Covering a wide range of subjects and beautifully illustrated, Imaging in Parkinson's Disease is a valuable reference for neurologists, neurosurgeons and neuropsychologists, and a helpful resource for students engaged in postgraduate biomedical and clinical training.

Breast MRI has emerged as a valuable adjunct to the conventional imaging modalities in the detection of primary and recurrent breast cancer. Yet, most radiologists who rely on MRI do not have knowledge of the fundamentals so essential to achieving and maintaining high image quality. With a focus on the basic imaging principles of breast MRI rather than on mathematical equations, this book takes a practical approach to imaging protocols that helps radiologists increase their diagnostic effectiveness. The text walks the reader through the basics of MRI, making it especially accessible to beginners. From a detailed outline of equipment prerequisites for obtaining high quality breast MRI to instructions on how to optimize image quality, expanded discussions on how to obtain optimized dynamic information, and explanations of good and bad imaging techniques, the book covers the topics that are most relevant to performing breast MRI.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.The latest advances in vibrational spectroscopic biomedical imagingWritten by expert spectroscopists, Vibrational Spectroscopic Imaging for Biomedical Applications discusses recent progress in the field in areas such as instrumentation, detector technology, novel modes of data collection, data analysis, and various biomedical applications. This full-color volume covers various IR imaging techniques, including transmission reflection, transflection, and attenuated total reflection (ATR) imaging, and Raman imaging. The efficient use of vibrational spectroscopy in clinical applications is emphasized in this state-of-the-art guide. Coverage includes: Automated breast histopathology using mid-IR spectroscopic imaging Synchrotron-based FTIR spectromicroscopy and imaging of single algai cells and cartilage Preparation of tissues and cells for infrared and Raman spectroscopy and imaging Evanescent wave imaging sFTIR, Raman, and surface-enhanced Raman spectroscopic imaging of fungal cells Widefield Raman imaging of cells and tissues Resonance Raman imaging and quantification of carotenoid antioxidants in the human retina and skin Raman microscopy for biomedical applications--efficient diagnosis of tissues, cells, and bacteria The current sate of Raman imaging in clinical application Vibrational spectroscopic imaging of microscopic stress patterns in biomedical materials Tissue imaging with coherent anti-Stokes Raman scattering microscopy

A comprehensive reference of cutting-edge advanced techniques for quantitative image processing and analysis

Medical diagnostics and intervention, and biomedical research rely progressively on imaging techniques, namely, the ability to capture, store, analyze, and display images at the organ, tissue, cellular, and molecular level. These tasks are supported by increasingly powerful computer methods to process and analyze images. This text serves as an authoritative resource and self-study guide explaining sophisticated techniques of quantitative image analysis, with a focus on biomedical applications. It offers both theory and practical examples for immediate application of the topics as well as for in-depth study.

Advanced Biomedical Image Analysis presents methods in the four major areas of image processing: image enhancement and restoration, image segmentation, image quantification and classification, and image visualization. In each instance, the theory, mathematical foundation, and basic description of an image processing operator is provided, as well as a discussion of performance features, advantages, and limitations. Key algorithms are provided in pseudo-code to help with implementation, and biomedical examples are included in each chapter.

Image registration, storage, transport, and compression are also covered, and there is a review of image analysis and visualization software. The accompanying live DVD contains a selection of image analysis software, and it provides most of the algorithms from the book so readers can immediately put their new knowledge to use.

Members of the academic community involved in image-related research as well as members of the professional R&D sector will rely on this volume.
It is also well suited as a textbook for graduate-level image processing classes in the computer science and engineering fields.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. 295 cases and more than 1700 illustrations teach you how to accurately interpret genitourinary tract images 4 STAR DOODY'S REVIEW! "The high-quality images and pithy discussions make this book very useful to radiologists, both in training and in practice....The book's best features are the excellent image quality, the inclusion of images of differential diagnostic considerations, and concise discussions of the cases. This is an excellent resource for radiologists in training and in practice. The case-based format is excellent for board preparation, and its concise prose provides all the necessary information while leaving out the excess."--Doody's Review Service Genitourinary Imaging Cases presents an efficient and systematic approach to examining images of the genitourinary system. You will find an unmatched collection of 295 cases ranging from normal anatomy to the full spectrum of disease -- including renal cystic masses, renal infection, renal vascular disease, and female pelvic abnormalities. Included with these cases are 1700+ high-quality images that are representative of what you would see on various imaging modalities. The book's easy-to-navigate organization is specifically designed for use at the workstation. The concise text, numerous images, and helpful icons speed access to essential information and simplify the learning process. Features: Each case includes findings, differential diagnosis, comment/discussion, and clinical pearls Icons, a grading system depicting the full spectrum of diseases, common to rare, and imaging findings, typical to unusual, along with the consistent chapter organization make this perfect for rapid at-the-bench consultation Strong focus on pathology Special emphasis on the latest diagnostic modalities that include both CT and MR images

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Essential light scattering theories, techniques, and practices Extend tissue characterization and analysis capabilities using cutting-edge biophotonics tools and technologies. This comprehensive resource details the principles, devices, and procedures necessary to fully employ light scattering in clinical and diagnostic applications. Biomedical Applications of Light Scattering explains how to work with biological scatterers and scattering codes, accurately model tissues and cells, build time-domain simulations, and resolve inverse scattering issues. Noninvasive biopsy procedures, precancer and disease screening methods, and fiber optic probe design techniques are also covered in this detailed volume. Analyze light scattering spectra from complex and continuous media Build high-resolution cellular models using FDTD and PSTD methods Work with confocal microscopic imaging and diffuse optical tomography Measure blood flow using laser Doppler, LSCI, and photon correlation Perform noninvasive optical biopsies using elastic scattering techniques Assess bulk tissue properties using differential pathlength spectroscopy Detect precancerous lesions using angle-resolved low-coherence interferometry Risk-stratify patients for colonoscopies using enhanced backscattering methods

In "CT Suite" the doctor and anthropologist Barry F. Saunders provides an ethnographic account of how a particular diagnostic technology, the computed tomographic (CT) scanner, shapes social relations and intellectual activities in and beyond the CT suite, the unit within the diagnostic radiology department of a large teaching hospital where CT images are made and interpreted. Focusing on how expertise is performed and how CT images are made into diagnostic evidence, he concentrates not on the function of CT images for patients but on the function of the images for medical professionals going about their routines. Yet Saunders offers more than insider ethnography. He links diagnostic work to practices and conventions from outside medicine and from earlier historical moments. In dialogue with science and technology studies, he makes a significant contribution to scholarship on the visual cultures of medicine.

Saunders's analyses are informed by strands of cultural history and theory including art historical critiques of realist representation, Walter Benjamin's concerns about violence in "mechanical reproduction," and tropes of detective fiction such as intrigue, the case, and the culprit. Saunders analyzes the diagnostic "gaze" of medical personnel reading images at the viewbox, the two-dimensional images or slices of the human body rendered by the scanner, methods of archiving images, and the use of scans as pedagogical tools in clinical conferences. Bringing cloistered diagnostic practices into public view, he reveals the customs and the social and professional hierarchies that are formulated and negotiated around the weighty presence of the CT scanner. At the same time, by returning throughout to the nineteenth-century ideas of detection and scientific authority that inform contemporary medical diagnosis, Saunders highlights the specters of the past in what appears to be a preeminently modern machine.

A must-read for anyone working in electronics in the healthcare sector This one-of-a-kind book addresses state-of-the-art integrated circuit design in the context of medical imaging of the human body. It explores new opportunities in ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), nuclear medicine (PET, SPECT), emerging detector technologies, circuit design techniques, new materials, and innovative system approaches. Divided into four clear parts and with contributions from a panel of international experts, Medical Imaging systematically covers: X-ray imaging and computed tomography-X-ray and CT imaging principles; Active Matrix Flat Panel Imagers (AMFPI) for diagnostic medical imaging applications; photon counting and integrating readout circuits; noise coupling in digital X-ray imaging Nuclear medicine-SPECT and PET imaging principles; low-noise electronics for radiation sensors Ultrasound imaging-Electronics for diagnostic ultrasonic imaging Magnetic resonance imaging-Magnetic resonance imaging principles; MRI technology

Prostate cancer is one of the most common malignancies in men in the Western world. Although a wide range of treatment regimens are available for this disease, there are few evidence-based guidelines for treatment selection. This volume describes the clinical value of imaging for improving not only staging and treatment selection, but also the diagnosis, treatment planning, and treatment follow-up for patients with prostate cancer.
A multidisciplinary disease management approach is critical in this disease. For the radiologist, understanding the pathophysiology, critical clinical issues, and advantages and limitations of different treatments is essential for meaningful interpretation of imaging studies. Similarly, for the practicing clinician, understanding the advantages and limitations of imaging modalities and the importance of optimal technique are crucial to the rational use of imaging. This volume serves as a valuable reference for radiologists, urologists, medical and radiation oncologists and all practitioners involved in the management of prostate cancer.

Doktorarbeit / Dissertation aus dem Jahr 2007 im Fachbereich Medizin - Radiologie, Nuklearmedizin, Note: magna cum laude, Universitat zu Koln (Klinik und Poliklinik fur Nuklearmedizin), 112 Quellen im Literaturverzeichnis, Sprache: Deutsch, Abstract: Nach Radioiodtherapie (RIT) stellt der Patient fur seine Umwelt (Angehorige, Personal auf Therapiestation und Unbeteiligte) eine Strahlenquelle dar. Die chemische Form des exhalierten Radioiods nach erfolgter RIT ist dabei ein wichtiger Faktor zur Beurteilung der zu erwartenden effektiven Dosis infolge von Inhalation. Die Bioverfugbarkeit wird in der Reihenfolge elementares Iod > aerosolische Iodformen > organisch gebundenes Iod jeweils um den Faktor 10 verringert. Somit ist aus Sicht des Strahlenschutzes eine Radioiodexhalation in moglichst vollstandig organisch gebundener Form wunschenswert. In der vorliegenden Arbeit wurde Ausmass und chemische Form der Radioiodexhalation in Tierexperimenten exogen moduliert und untersucht. Die Ergebnisse zeigen, dass Schilddrusenmedikamente einen Einfluss auf die Radioiodexhalation nach 131I]-Applikation haben. Bei unbeeinflusster Schilddruse wird das 131I] zum Grossteil in organisch gebundener Form abgeatmet. Bei der Kaliumiodid (KI) und Perchloratgruppe konnte gezeigt werden, dass der organisch gebundene Iodanteil mit steigender Blockierung der Schilddruse abnimmt. Der elementare Iodanteil vergrossert sich gegenlaufig. Es konnte ferner gezeigt werden, dass das Ausmass dieser Veranderung der prozentualen Verteilung der unterschiedlichen Radioiodformen im Exhalat von der Menge des praapplizierten Medikaments abhangig ist. Die KI und Perchlorat Gruppen lassen vermuten, dass mit steigender Blockade die Menge des exhalierten Iods ansteigt. Die Bestimmung des absoluten Anteils des durch Exhalation eliminierten Iods lieferte Werte zwischen 0,21 und 0,54 %. Diese Werte sind grossenordnungsmassig gut mit den bisher beim Menschen bestimmten Werten vergleichbar. Thyreostatika konnen fo

The only complete work on vascular hemodynamics
Recently, vascular hemodynamics has undergone major advances, resulting from increasingly sophisticated imaging, computational, and clinical research methodologies. The effects of these advances are likely to be profound at both the scientific and clinical levels. Now, Vascular Hemodynamics provides a self-contained treatment of this rapidly advancing topic as it relates to vascular disease and related pathologies in the human body.
Utilizing a multidisciplinary approach encompassing engineering, vascular biology, vascular imaging, and clinical practice, the book provides a survey of the basic science and clinical research in hemodynamics of the vasculature. The topics presented involve sophisticated modeling, imaging, and measurement techniques. The text emphasizes both the technical and clinical aspects of the field.
Additionally, Vascular Hemodynamics:
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Includes a wide variety of models of vascular pathology, including physical models, finite-element models, linear-system models, transmission-line models, and dye-dilution models
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Discusses diverse pathologies of the large vessels, the microvasculature, and the systematic vasculature
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Brings together a range of imaging modalities related to hemodynamics
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Includes both introductory-level and research-oriented material on each topic
Vascular Hemodynamics is the only single-text treatment of this important topic, making it a vital reference for researchers and students of bioengineering, radiology, vascular surgery, neurology, nephrology, cardiology, and oncology.

The new edition of Physics for Medical Imaging has been fully updated to reflect the latest advances in technology and legislation and the needs of today's radiology trainees. Invaluable reading, particularly for those sitting the primary and final examinations of the Royal College of Radiology, UK, the book will also be of value to radiographers and personnel interested in medical imaging. The concise text is also accompanied by clear line drawings and sample images to illustrate the principles discussed. Closely matches needs of FRCR examination candidates. Updated to reflect changes to FRCR examination. More medically orientated. Covers new legislation concerning radiological safety etc. 'Must-know' summaries at end of each chapter. Completely new design.

This book describes an optical clearing method based on reversible reduction of tissue scattering due to refractive index matching of scatterers and ground matter. This technique, which has been of great interest for research and application in the last decade, is a promising technique for future developments in the fields of tissue imaging, spectroscopy, phototherapy, and laser surgery.

This book addresses the question 'What is physics for?' Physics has provided many answers for mankind by extending his ability to see. Modern technology has enabled the power of physics to see into objects to be used in archaeology, medicine including therapy, geophysics, forensics and other spheres important to the good of society. The book looks at the fundamental physics of the various methods and how they are used by technology. These methods are magnetic resonance, ionising radiation and sound. By taking a broad view over the whole field it encourages comparisons, but also addresses questions of risk and benefit to society from a fundamental viewpoint. This textbook has developed from a course given to third year students at Oxford and is written so that it can be used coherently as a basis for shortened courses by omitting a number of chapters.