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Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development > Reproductive medicine > Infertility & fertilization
For many years, the focus of fertility research and treatment has been the female. In reality, at least half of all infertility cases have a male factor as a major or contributing cause. Recent advances in the diagnosis and treatment of male infertility have enabled pregnancies in cases where the male partner was previously considered to be untreatable or even sterile. With contributions from world- renowned experts, this comprehensive overview of male infertility covers anatomy, evaluation, treatment and prevention. The elucidation of the molecular genetics underpinning spermatogenesis and the development of new sperm function tests have increased our understanding of male infertility and led to new treatments which are discussed and evaluated. This volume presents the latest scientific developments in a clinically useful and practical format. The book is packaged with a high-quality surgical atlas on CD- ROM. This text will be valuable for urologists and reproductive endocrinologists at all levels.
Fertility Fuel is an integrative approach to understanding and overcoming infertility. While most fertility clinics thrive on scary statistics and over-medicalized interventions, it is possible to create your family without fear and desperation. Laying out five steps to get one's body in the best possible state to say YES to fertility, Fertility Fuel examines widely accepted western medicine protocols as well as the integration of adjunct therapies to improve fertility results. It discusses options and possible treatments that may not be on the patient's current radar and helps couples separate facts from scare tactics in their fertility quest. Founded in clinical experience as well as current exposure to modern integrative practices, Fertility Fuel is a patient advocate handbook for helping couples create a family.
This highly effective programme for women struggling to become pregnant draws on the proven, centuries-old techniques of traditional Chinese medicine to cure infertility. Dr Lewis explains in clear, accessible prose how any woman can identify the imbalances in her body - and how these imbalances can then be treated with a simple plan that entails lifestyle changes, diet, herbs and acupressure. On its own or in conjunction with traditional Western medical treatments, THE INFERTILITY CURE offers women hope - and what they desire most: a healthy baby. 'Lewis simplifies many complex concepts, such as the theory that there are four vital substances in the body (Yin, Yang, Qi, and Blood) and that they're likely to be suffering from imbalance caused by energy excess, deficiency, or stagnation' - Publishers Weekly
Reproductive medicine and surgery is a major subspecialty in the practice of obstetrics and gynaecology. This textbook provides an introduction to the field of subfertility and reproductive endocrinology, with contributions written by leading experts in the field. This book is based on and compliments a training programme run jointly by the British Fertility Society and the Royal College of Obstetricians and Gynaecologists, making it an indispensable handbook for medical trainees. It will also appeal to clinicians embarking on a career in obstetrics and gynaecology who want an excellent grounding in this area. Specialist nurses will also find the book a valuable resource, and scientists specialising in reproductive medicine and embryology will gain insight into the related clinical areas.
‘A vital, heartfelt read for anyone navigating the rough seas of infertility and pregnancy loss’ – Leah Hazard, author of Hard Pushed An insightful, moving memoir, capturing life working as a midwife in a busy NHS hospital at the same time as dealing with experiences of infertility, IVF and loss. As a young married couple, Sophie Martin and her husband spent years trying to conceive. They went through several rounds of IVF, at great expense, and even travelled overseas for treatment, never quite knowing whether they would one day have a family. Alongside this, Sophie was working hard at a job she loved: looking after expectant mothers and newborn babies as a midwife in a busy hospital, where the patients’ daily new additions were a constant reminder of Sophie’s own setbacks in pursuit of motherhood. The Infertile Midwife is a deeply personal, moving account of chasing something that you want so desperately. It also offers a much-needed look at how society treats infertility – from the language we use to the small talk we make – and the ways in which we can all do more to make things better for hopeful parents. With great warmth and honesty, Sophie shares her experiences of the bursts of hope and moments of great loss, but also the humour, love and joy that can be found in even the darkest places.
The last step in the IVF treatment cycle, embryo transfer, is also the process with the highest failure rate. No matter how good the laboratory technique is, a successful pregnancy will not be achieved without meticulous preparation of the uterus to accept the embryo. This book reviews the scientific evidence on endometrial receptivity, including histological, hormonal, biochemical, and immunological factors. Practical and concise, it supports gynecologists and embryologists to make evidence-based decisions that can influence the success rates of implantation and live births. Part of a series of books offering treatments and strategies for fertility and conception to optimize IVF outcomes, this volume is for all clinicians and embryologists working in reproductive medicine.
"Introducing the only clinically proven program--steeped in ancient
Chinese healing traditions--that has enabled hundreds of infertile
couples to conceive.
This second edition of the essential guide for reproductive professionals is now available in a Clinical Guide and a Case Studies Guide, presenting the most current knowledge on counseling patients with diverse needs amidst rapidly advancing modern technology. The Case Studies guide relates the accessible, real-world experiences and perspectives as leading international practitioners share their stories applying clinical concepts to treatment practice. Chapters cover current, unaddressed and emerging areas in reproductive mental health including consequences of direct-to-consumer DNA testing, racial and cultural sensitivity and tele-mental health. Among the new topics are transgender ART, recurrent pregnancy loss, post-partum adjustment, and the pregnant therapist. For an in-depth presentation of clinical concepts, discover the Clinical Guide, which provides a foundational understanding of the medical and psychosocial experience of fertility treatment. An essential aid for medical and mental health professionals, this comprehensive guide allows clinicians to develop and refine the skills required to address the increasingly complex needs of fertility patients.
The 1990s marked a new era in family formation. Increased access to donor sperm enabled single women and lesbian couples to create their families on their own terms, outside the bounds of heterosexual married relationships. However, emerging "alternative" families were not without social and political controversy. Women who chose to have children without male partners faced many challenges in their quest to have children. Despite current wider social acceptance of single people and same sex couples becoming parents, many of these challenges continue. In Romancing the Sperm, Diane Tober explores the intersections between sperm donation and the broader social and political environment in which "modern families" are created and regulated. Through tangible and intimate stories, this book provides a captivating read for anyone interested in family and kinship, genetics and eugenics, and how ever-expanding assisted reproductive technologies continue to redefine what it means to be human.
Having Your Baby Through Egg Donation is a helpful, authoritative guide to negotiating the complex and emotive issues that arise for those considering whether or not to pursue egg donation. It presents information clearly and with compassion, exploring the practical, financial, logistical, social and ethical questions that commonly arise. This fully updated second edition also includes recent developments in the field, including travelling for egg donation and the emerging field of epigenetics. This book will be valued by all those considering or undergoing donor conception, as well as the range of professionals who support them, including infertility counsellors, psychologists, therapists and social workers.
This new volume in the Reproductive Medicine for Clinicians series focuses on the practical clinical impact of problems linked to infertility, discussing topics such as luteal support in ART cycles, ovulation induction using pulsatile administration of GnRH, how to deal with the metabolic changes in PCOS, treatment to restore fertility in endometriosis and how to improve implantation, which are common aspects of daily clinical practice. It also addresses significant novel areas like the biological clock in human reproduction, reproduction at advanced parental age and medical and social egg freezing, offering valuable insights for patients and their doctors. Further, the book covers various areas of growing importance, such as how to access the uterine cavity; the future of imaging in reproduction; non-invasive prenatal testing; ART and male infertility; as well as breast cancer and fertility preservation. Last but not least, it examines the medical, ethical and legal aspects of a number of challenges for current and future reproductive medicine, including uterine transplantation and human genetic modification. Bringing together updates on some of the most important problems in reproductive medicine and also covering ethical and legal bases, this book offers an overview of potential treatments for infertility. As such, it is a valuable resource for gynecologists, obstetricians, endocrinologists and all specialists dealing with reproductive health.
An original graphic novel based on the IVF stories of its husband-and-wife authors and the 1-in-50 couples around the world like them. Conrad and Joanne met in their final year of university and have been virtually inseparable since then. For a while, it felt like they had all the time in the world. Yet now, when they are finally ready to have kids, they find that getting pregnant isn't always so easy. Ahead of them lies a difficult, expensive, and emotional journey into the world of assisted fertility, where each 'successful' implantation is followed by a two-week wait to see if the pregnancy takes. Join Joanne and Conrad, their friends, their family, their coworkers, and a stream of expert medical practitioners as they experience the highs and the lows, the tears and the laughter in this sensitive but unflinching portrayal of the hope and heartbreak offered to so many by modern medicine.
'Essential reading for anyone who has been through the sadness of a lost pregnancy' The Times 'Sensitive and insightful' Sunday Times Style 'This book will be a godsend to any woman going through the murky devastation that is called miscarriage but feels like something else entirely: the loss of a baby' Ariel Levy 'A compassionate, nuanced book that does this very complicated grief justice' Pandora Sykes 'This book will be the friend to hold your hand while you navigate your own pathway of grief. I'm so glad it's here' Elle Wright Beyond Grief also contains interviews with experts and other women who have experienced losses of their own, including Elizabeth Day, Leandra Medine Cohen, Melissa Odabash, Jools Oliver, Alexandra Stedman and Latham Thomas. Pippa Vosper tragically lost her son Axel in 2017, when she was five months pregnant, and has since written about miscarriage and baby loss online and in a series of pieces for Vogue. Beyond Grief: Navigating the Journey of Pregnancy and Baby Loss is the book she wishes had been available when her son died. It covers every aspect of pregnancy and baby loss at any stage, from the practical to the emotional, with advice from experts and stories from women who have been through it themselves. Beyond Grief offers both an inclusive perspective and a guiding hand to anyone who has experienced any kind of pregnancy loss, as well as those who are trying to support them through it.
The 1990s marked a new era in family formation. Increased access to donor sperm enabled single women and lesbian couples to create their families on their own terms, outside the bounds of heterosexual married relationships. However, emerging "alternative" families were not without social and political controversy. Women who chose to have children without male partners faced many challenges in their quest to have children. Despite current wider social acceptance of single people and same sex couples becoming parents, many of these challenges continue. In Romancing the Sperm, Diane Tober explores the intersections between sperm donation and the broader social and political environment in which "modern families" are created and regulated. Through tangible and intimate stories, this book provides a captivating read for anyone interested in family and kinship, genetics and eugenics, and how ever-expanding assisted reproductive technologies continue to redefine what it means to be human.
This comprehensive review of the factors that affect the harvesting and preparation of oocytes and the management of embryos will allow practitioners to make evidence-based decisions for successful IVF. The book reviews and re-considers the value of strategies and outcomes in the management of fertility and conception rates, centred on the production of oocytes, and successful development of the embryo. Authored by leading experts in the field, chapters engage with treatments and strategies that affect the production of oocytes and embryos, optimizing outcomes in the management of female fertility, conception rates, and live births. This vital guide covers controlled ovarian hyperstimulation, the role of AMH in determining ovarian reserve, and primary stimulation agents and the use of adjuncts. Integral for all clinicians and embryologists working in reproductive medicine units, readers are provided with evidence-based, comprehensive advice and review of all factors affecting the management of oocytes and the embryo that are vital for successful IVF cycles.
In order to maximize the chance of IVF success, couples need to ensure that their preconceptual health is optimal to increase the quality of gametes and reproductive fitness. This text reviews the medical and lifestyle factors that can affect the body at preconception stage, such as micronutrients, stress, hormonal and gynecologic assessment, as well as environmental factors such as optimal weight and age for childbirth. This book will enable all medical practitioners and healthcare professionals to give evidence-based advice to influence the success rate of subsequent IVF cycles, and ensure that every child is born in the best possible condition. Part of a four-book series on optimizing different aspects of the IVF cycle, this book focusses on preparing the body for assisted conception. Other books in the series focus on the egg and embryo, the endometrium, and the sperm.
Public concern over high-profile mistakes in IVF clinics and the concomitant increase in governmental regulation, have given rise to widespread recognition of the need for accreditation of IVF clinics. Modern accreditation schemes are largely based on the principles of ISO 9001 and related standards, at the heart of which lies the expectation of a formal quality management system. Risk analysis and risk minimization are also being demanded of IVF clinics, but many only have limited understanding of how to approach these essential management tasks. This book brings together the basics of quality management and risk management, focussing on 'prophylactic management' - prevention rather than cure. Each chapter in this new edition is fully updated and extended to include new material such as, quality and risk management in the ART clinic, and an illustrative example of a 'well-run' clinic. This is the essential guide for clinicians and IVF laboratory staff.
This concise guide to the often overlooked association between erectile dysfunction and hypertension/cardiovascular disease covers a wide range of aspects of importance to the clinician. It examines the impact of antihypertensive drug therapy on erectile function and explains how the management of erectile dysfunction in hypertensive patients depends on a variety of factors. Different treatment approaches are described, including lifestyle modification, PDE-5 inhibitors and other novel agents and behavioral therapy and helpful therapeutic algorithms are presented. A further focus of the book is the potential role of erectile dysfunction as an early diagnostic indicator of asymptomatic coronary artery disease and a prognostic marker for cardiovascular events. In addition, key background information is supplied on epidemiology and pathophysiology, and the significance of erectile dysfunction in different patient groups, such as the elderly and those with chronic kidney disease, is examined. Erectile dysfunction is a major public health problem affecting more than ten percent of the general male population and is now considered to be predominantly of vascular origin. This book will be informative and of practical value for all practitioners responsible for caring for the very many patients who experience erectile dysfunction in the setting of hypertension and cardiovascular disease.
There is no clearer testament to the importance and efficacy of in vitro fertilization in the treatmentof the infertilepatient than the fact that over one million babies have been born since its clinical introduction in 1978. The successof this worldwideendeavorhas evolvedto treat some of the formerly most intractable forms of infertility and requires individuals with different skills and insights whose activities are often compartmentalized into clinical, laboratory and research functions. The intent of Essential lVF is to present current issues in clinical IVF that encompass the varied activities of those engaged in this enterprise. By integrating clinical, basic research and laboratory-related aspects of human reproduction, readers with diverse interests should obtain a more complete understanding of the impact, importance and inter-relatedness of each in the progress of infertility treatment, and an appreciation of whether emerging technologies will or should contribute to this progress in the near future. The topics selected for this volume include research that has begun to explain the origins of differential follicular, gamete, embryo and uterine competence, and specific laboratory procedures and protocols that may have important clinical implications forthe generation ofdevelopmentally viable embryos. Human embryoresearchoverthe past 25 years has notonly confirmed that the developmental potential of each embryo is unique, but more importantly, demonstrated how genetic and nongenetic factors for sperm and oocyte determineembryo competencewell before fertilization. Several chapters deal with the origins of normal and compromised gametes and how those with high competence can be identified and isolated for fertilization.
This concise, truncated version of Nagy, Varghese and Agarwal's Practical Manual of In Vitro Fertilization is comprised of select practical chapters for a portable, affordable and up-to-date resource. Building and Managing an IVF Laboratory covers a variety of topics, including: - Setting up and running an IVF laboratory - IVF laboratory equipment and culture systems - Organization of the IVF unit - Licensing and regulation in the ART laboratory - Quality control and troubleshooting Practical for both clinicians and researchers alike, Building and Managing an IVF Laboratory brings together all of the need-to-know information about these important topics in reproductive medicine.
From its crude and uneasy beginnings thirty years ago, Chinese sperm banking has become a routine part of China's pervasive and restrictive reproductive complex. Today, there are sperm banks in each of China's twenty-two provinces, the biggest of which screen some three thousand to four thousand potential donors each year. Given the estimated one to two million azoospermic men--those who are unable to produce their own sperm--the demand remains insatiable. China's twenty-two sperm banks cannot keep up, spurring sperm bank directors to publicly lament chronic shortages and even warn of a national 'sperm crisis' (jingzi weiji). Good Quality explores the issues behind the crisis, including declining sperm quality in the country due to environmental pollution, as well as a chronic national shortage of donors. In doing so, Wahlberg outlines the specific style of Chinese sperm banking that has emerged, shaped by the particular cultural, juridical, economic and social configurations that make up China's restrictive reproductive complex. Good Quality shows how this high-throughput style shapes the ways in which men experience donation and how sperm is made available to couples who can afford it.
The complete guide to getting pregnant and improving fertility naturally - even if you've been told your chances of conception are low Worried about your ability to have children in the next five years? Have you been trying to get pregnant for a while now and it's just not happening? Does it seem like every woman you know is having a hard time getting pregnant and you don't want that to be you when you're ready? Do you want natural, non-invasive options to conceive? If you answered "yes" to any one of these questions, "Yes, You Can Get Pregnant" is for you. A nationally renowned women's health and fertility expert, Aimee Raupp has helped hundreds of women optimize their fertility and get pregnant, even after age 40. Here, she provides her complete program for improving your chances of conceiving and overcoming infertility, including the most effective complementary and lifestyle approaches and the latest nutritional advice. Her remedies help you how to get in tune with your body, eat the best fertility-enhancing foods, and avoid environmental toxins to achieve a healthy and stress-free pregnancy. In a friendly, understanding, and inspirational manner, "Yes, You Can Get Pregnant" provides hope, scientifically-backed knowledge, and emotional support to help you become the mother you want to be.
This concise, truncated version of Zini and Agarwal's Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction offers select, clinical chapters for a handy, more affordable, state-of-the-art resource. Sperm Chromatin for the Clinician addresses such vital issues as: -Male subfertility and sperm chromatin damage -Aging and sperm DNA damage -Cancer and implications for sperm quality -Environmental factors -Cryopreservation and sperm DNA integrity -Postnatal effects of sperm chromatin damage Practical for clinicians and researchers alike, Sperm Chromatin for the Clinician contains all of the need-to-know information about this cutting-edge topic in reproductive medicine. "
This concise, truncated version of Parekattil and Agarwal's" Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants" is the first resource dedicated solely to clinicalissues of infertility. With select chapters that will prove invaluable to the reproductive medicine clinician, "Male Infertility for the Clinician"addresses issues like: - Diagnosis and management of male infertility conditions such as varicocele, ejaculatory duct obstruction and congenital epididymal obstruction - New approaches to Klinefelter's syndrome - A concise structured approach to the genetics of male infertility - Management of cancer patients (oncofertility) and ethical considerations in special male infertility circumstances -New advances in biomaterials for reconstruction and new robotic-assisted microsurgical techniques Practical for clinicians and researchers alike, "Male Infertility for the Clinician"contains all of the need-to-know information about these cutting-edge topics in reproductive medicine. |
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