A powerful, personal reflection on miscarriage from an acclaimed health and science journalist, drawing on original interviews and ground-breaking research to offer fresh insight into this underacknowledged subject. After losing four pregnancies with no obvious cause, Jennie Agg set out to understand why miscarriage remains such a profoundly misunderstood, under-researched and under-acknowledged experience. Part-memoir, part-scientific investigation, Life, Almost documents Agg's path to motherhood and her search for answers. Tracing each tentative step of her fifth pregnancy - as her body becomes a creature she does not wish to spook - Agg dismantles the myths that we unquestioningly accept about our reproductive lives- Why are we told miscarriage can't be prevented when half of all miscarriages are of perfectly healthy embryos? Why is it normal not to tell anyone you're pregnant for the first three months? Why don't we know why labour starts? Drawing on pioneering research and interviews with world-leading experts, Life, Almost is a ground-breaking book that will change how you think about miscarriage, and a moving reflection on grief and love at the edge of life as we understand it.

Has the college experience of women been an influence on the number of children desired and the number and spacing of their children? Do women come to college with their attitudes and values in this regard already formed? This study of 15,000 women, freshmen and seniors in 45 American colleges and universities, both secular and nonsecular, attempts to answer this question and to determine how such characteristics as religious preference, career intentions, and the number of children in her own family influence a woman's fertility values. Attention is paid to an earlier finding that Catholic college graduates have higher fertility than Catholic high school graduates, although higher education is usually associated with lower fertility. Originally published in 1967. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Why do American couples differ in the number of children they have? To answer this question the first major longitudinal study in American fertility was begun in 1957 with a series of interviews with parents of two children. Family Growth in Metropolitan America (1961) and The Third Child (1963) reported the results of the first two phases of this research project. In this book, in addition to evaluating the longitudinal design of the study, the authors report the results of the third and final interviews, a decade after the first, and attempt to answer such questions as: How well are couples able to predict their own fertility over the years? To what extent does the number of children desired affect the spacing of births? How is fertility affected by peer group relations, by the wife's participation in the labor force, by religion? Originally published in 1971. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

"Selected by" Choice" magazine as an Outstanding Academic Title for 1996""[Marsh and Ronner make for] a highly successful combination in which faultless clinical detail and a broad social and cultural approach are seamlessly woven to produce a very impressive and beautifully written historical work of the first importance." -- Irvine Louden, "Journal of the Social History of Medicine"

In "The Empty Cradle," Margaret Marsh and Wanda Ronner delve into the origins of the many misconceptions surrounding infertility as they explore how medical and cultural beliefs emerged throughout its controversial history. Drawing on a wide variety of sources -- including intimate diaries and letters, patient records, memoirs, medical literature, and popular magazines -- "The Empty Cradle" investigates the social, cultural, scientific, and medical dimensions of infertility over the past three hundred years.

Marsh and Ronner explore reactions -- among both physicians and husbands -- to the emerging scientific evidence that infertility was a condition for which men and women bear equal responsibility. The book concludes that infertility is still a subject affected by myth and misunderstanding. A lively and compelling history of a complex medical and cultural phenomenon, "The Empty Cradle" brings a valuable perspective to current debates about how we should think about and address the experience of infertility in our own time.

"Marsh and Ronner have sought to go beyond the published medical literature to disclose the voices of those most affected by the physiological and cultural condition of infertility... they have restored to the historical record the anguish and the hopes of women whoexperienced infertility." -- Rima D. Apple, "American Historical Review"

"The book's lucid explanations of medical terms and procedures will allow me to recommend it to my infertility patients. I plan to do so, trusting that it will give them a new perspective on their predicament. Knowing that it provided me a new perspective on both infertility and the practice of gynecology, I will also assign it an honored place in my medical library." -- Janet E. Shepherd, M.D., "Journal of the American Medical Association"

" "The Empty Cradle" demonstrates the profound impact of politics as well as culture on the development of medical practice. It is an excellent model for future scholarship on the complex relationship between science and society." -- Elaine Tyler May, "Journal of the History of Medicine and Allied Sciences"

The increasing understanding of individual differences in response to in-vitro fertilization (IVF) treatment, resulting from genetic and ethnical differences, has increased the potential for individualized treatment for patients, resulting in improved pregnancy and live-birth outcomes. This illustrated book summarizes, and provides updates on, the most recent developments in individualized infertility treatment and embryo selection techniques. Individualization is not only confined to the different steps in the ovarian stimulation process and the luteal phase support, but also to embryo selection techniques, which include, among others, the analysis of embryo development pattern and genetic testing. Chapters cover a multitude of topics, ranging from oocyte maturation and immunological testing to fertilization technique in the IVF laboratory and preparation for optimal endometrial receptivity in cryo cycles. Essential reading for IVF specialists and embryologists in IVF Clinics and also an important text for medical consultants specializing in reproductive medicine, gynecology and embryology.

'Reproflexology' - the study and treatment of male and female reproductive and fertility conditions using reflexology - is aspecialist therapy that has been pioneered and carefully developed by Barbara Scott over 20 years. The therapy can be applied either as a stand-alone treatment to support natural conception or alongside fertility treatment. This is the first book to be published on treating fertility issues using reflexology.Reproductive reflexology can be a minefield with much conflicting advice being given about what practitioners can and cannot do. Because of this many practitioners choose not to work with clients who are having fertility issues. In this book Barbara Scott gives clear guidance on how to gain information from clients, how to interpret that information, how to plan treatment and what reproflexology techniques to use. This will give practitioners the knowledge and confidence to work with clients who have a wide range of reproductive conditions and who are trying to conceive.

Surrogacy is India's new form of outsourcing, as couples from all over the world hire Indian women to bear their children for a fraction of the cost of surrogacy elsewhere with little to no government oversight or regulation. In the first detailed ethnography of India's surrogacy industry, Amrita Pande visits clinics and hostels and speaks with surrogates and their families, clients, doctors, brokers, and hostel matrons in order to shed light on this burgeoning business and the experiences of the laborers within it. From recruitment to training to delivery, Pande's research focuses on how reproduction meets production in surrogacy and how this reflects characteristics of India's larger labor system.

Pande's interviews prove surrogates are more than victims of disciplinary power, and she examines the strategies they deploy to retain control over their bodies and reproductive futures. While some women are coerced into the business by their families, others negotiate with clients and their clinics to gain access to technologies and networks otherwise closed to them. As surrogates, the women Pande meets get to know and make the most of advanced medical discoveries. They traverse borders and straddle relationships that test the boundaries of race, class, religion, and nationality. Those who focus on the inherent inequalities of India's surrogacy industry believe the practice should be either banned or strictly regulated. Pande instead advocates for a better understanding of this complex labor market, envisioning an international model of fair-trade surrogacy founded on openness and transparency in all business, medical, and emotional exchanges.

Reproductive medicine and surgery is a major subspecialty in the practice of obstetrics and gynaecology. This textbook provides an introduction to the field of subfertility and reproductive endocrinology, with contributions written by leading experts in the field. This book is based on and compliments a training programme run jointly by the British Fertility Society and the Royal College of Obstetricians and Gynaecologists, making it an indispensable handbook for medical trainees. It will also appeal to clinicians embarking on a career in obstetrics and gynaecology who want an excellent grounding in this area. Specialist nurses will also find the book a valuable resource, and scientists specialising in reproductive medicine and embryology will gain insight into the related clinical areas.

This innovative book is one of the first resources to describe in detail the technique of digital time-lapse microscopy, a state-of-the-art analytical tool which is revolutionizing the field of assisted reproduction. Over 180 high-quality video sequences, accessible online via the password included in the book, provide a practical and highly visual guide to this new technology and the wealth of detail it can reveal about human embryo development. Written by a team of experts from across numerous clinical and scientific subspecialties, this book is a comprehensive guide to all aspects of the technique. It covers both the general principles of time-lapse microscopy and the specifics of working with various devices, with chapters on EmbryoScopeTM, Primo VisionTM and EevaTM as well as set-up and troubleshooting. Full electronic access to all text, images and supplementary videos makes this the ideal everyday reference for embryologists, clinicians and others working in IVF laboratories.

This highly effective programme for women struggling to become pregnant draws on the proven, centuries-old techniques of traditional Chinese medicine to cure infertility. Dr Lewis explains in clear, accessible prose how any woman can identify the imbalances in her body - and how these imbalances can then be treated with a simple plan that entails lifestyle changes, diet, herbs and acupressure. On its own or in conjunction with traditional Western medical treatments, THE INFERTILITY CURE offers women hope - and what they desire most: a healthy baby. 'Lewis simplifies many complex concepts, such as the theory that there are four vital substances in the body (Yin, Yang, Qi, and Blood) and that they're likely to be suffering from imbalance caused by energy excess, deficiency, or stagnation' - Publishers Weekly

For many years, the focus of fertility research and treatment has been the female. In reality, at least half of all infertility cases have a male factor as a major or contributing cause. Recent advances in the diagnosis and treatment of male infertility have enabled pregnancies in cases where the male partner was previously considered to be untreatable or even sterile. With contributions from world- renowned experts, this comprehensive overview of male infertility covers anatomy, evaluation, treatment and prevention. The elucidation of the molecular genetics underpinning spermatogenesis and the development of new sperm function tests have increased our understanding of male infertility and led to new treatments which are discussed and evaluated. This volume presents the latest scientific developments in a clinically useful and practical format. The book is packaged with a high-quality surgical atlas on CD- ROM. This text will be valuable for urologists and reproductive endocrinologists at all levels.

Infertility affects an estimated 50 million women worldwide and has a wide range of causes including eating disorders, smoking, chemotherapy, diseases such as STIs, as well as genetic factors and malformations. The preliminary assessment and diagnosis involves a potentially broad array of lab and imaging tests, physical examination and potentially genetic tests, after which a management plan is selected depending on the woman’s age, the cause(s) and duration of the infertility. Female Infertility: Core Principles and Clinical Management provides clinicians with a comprehensive understanding of how best to overcome infertility using the various treatment options now available. The book opens with an introduction to the anatomy and physiology of the female reproductive system before describing the assessment and investigative tools used in primary and secondary healthcare settings. Subsequent chapters describe how to secure optimum functionality of the ovaries, the measurement of ovarian reserves, stimulation protocols and the process of oogenesis and oocyte collection. Given their potential adverse impact on the quality of oocytes and implantation, dedicated chapters focus on the treatment of polycystic ovarian syndrome and endometriosis. Concluding chapters address fast moving and future technologies, including the use of pluripotent stem cells for treating different medical conditions; the management of mitochondrial disease and the transplantation of cryopreserved ovaries. Highly illustrated and written by a team of international experts in the field, Female Infertility: Core Principles and Clinical Management serves as an essential resource for all clinicians, nurses and clinical scientists who specialise in reproductive medicine, gynecology, oncology, infertility and embryology.

Fertility is one of the major health and wellbeing issues for modern women, and Emma Cannon's Total Fertility offers clear, warm and supportive advice to help you on your own unique fertility journey. This book will help you get pregnant now, whether you are going for natural or assisted conception, and also focus on fertility preservation to help you stay fertile longer so you can get pregnant in the future. Emma Cannon answers the many nagging questions women have about fertility and conception; questions such as: How can I get a sense of my fertility? Can I preserve my fertility? When exactly should we be having sex? Does my diet really matter? Does stress lower my chances of conceiving? What exercise should I be doing? Reducing stress and approaching fertility with a calm and positive attitude is central to her approach to getting pregnant, so Emma also helps you develop a 'fertile mindset' with a toolbox of simple suggestions to cultivate emotional wellness for your particular fertility 'type'. Written in Emma's trademark optimistic, warm and non-judgmental tone, Total Fertility is a book for anyone who is thinking - or has ever thought of - getting pregnant.

The last step in the IVF treatment cycle, embryo transfer, is also the process with the highest failure rate. No matter how good the laboratory technique is, a successful pregnancy will not be achieved without meticulous preparation of the uterus to accept the embryo. This book reviews the scientific evidence on endometrial receptivity, including histological, hormonal, biochemical, and immunological factors. Practical and concise, it supports gynecologists and embryologists to make evidence-based decisions that can influence the success rates of implantation and live births. Part of a series of books offering treatments and strategies for fertility and conception to optimize IVF outcomes, this volume is for all clinicians and embryologists working in reproductive medicine.

This extensively updated new edition provides an indispensable account of modern in-vitro fertilization practice, building upon the popularity of previous editions. The authors initially give a comprehensive review of the biology of human gametes and embryos, before outlining basic to advanced IVF techniques. New developments in practical techniques and understanding are discussed, including in-vitro maturation, vitrification, preservation of fertility for cancer patients, stem cell technology, preimplantation genetic testing, and the role of epigenetics and imprinting. The revised introduction also incorporates a 'refresher' study review of fundamental principles of cell and molecular biology, now updated with current knowledge of meiosis in human oocytes, embryo metabolism and basic principles of genome editing. With high-quality illustrations and extensive, up-to-date reading lists, it is a must-have textbook for trainee and practising embryologists, as well as clinicians who are interested in the scientific principles that underpin successful IVF.

'What would it mean to name this place I'm in, to map it? To say: this is the landscape. It looks like this, smells like this, at night these are the sounds that carry on the wind. Almost-motherhood . . .' When Miranda Ward and her husband decided to have a baby, they were young and optimistic. But five years, three miscarriages and one ectopic pregnancy later, she is still dealing with the ongoing aftermath of that decision, and the shadow it's cast over her relationship to her partner, her body and her future. In this searing, lyrical and radically honest memoir, Ward charts her journey through the uncertain landscape of almost-motherhood, asking questions of geography on the most intimate scale. How can we learn to be at home in our own bodies, even when we feel adrift from them? What language do we have for the spaces in between, the periods of wanting and waiting? And how do we maintain hope as we navigate towards an unknown future?

For around half of the couples who have trouble conceiving the cause of infertility is sperm-related. Intracytoplasmic sperm injection (ICSI) is the most common and successful treatment for male infertility. Here, the pioneers for the technique, along with authorities in the field, describe the underlying science of ICSI and other micromanipulation techniques. Practical advice for performing the techniques is covered in depth, including sperm selection, laser-assisted ICSI, and the use of piezo in ICSI. Examining the safety of ICSI in animal models as well as the impact of ICSI on the health and well-being of the children conceived through the procedure is discussed. This manual is an essential resource for clinical embryologists and laboratory personnel wishing to refine or develop techniques and improve outcomes.

Intrauterine insemination (IUI), also known as artificial insemination, is a fertility treatment that uses a catheter to place washed sperm directly into the uterus. Its aim is to increase the number of sperm reaching the fallopian tubes and subsequently increase the chances of fertilisation (American Pregnancy Association). This book is the first in a new series, Handbook on Infertility. Beginning with an overview of Intrauterine Insemination, the following chapters guide readers step by step through the process, from basic science to clinical application. Ethical, psychosocial and medicolegal aspects are also covered. Written by an internationally recognised author and editor team, this useful manual serves as a quick reference guide and includes photographs, illustrations and tables to enhance learning. Key points First title in new series Handbook on Infertility Presents complete overview of intrauterine insemination Includes chapters on ethical, psychosocial and medicolegal aspects Internationally recognised author and editor team

Infertility is a significant health issue and one that has received increasing media attention in the UK and elsewhere in recent years. For affected couples, it is the cause of substantial distress and feelings of isolation that can lead to associated anxiety and depression. This is compounded by a perceived lack of support from health services as well as a lack of available information regarding its management. This book provides current information and practical advice on the underlying causes, diagnosis and management of infertility in a clear and concise style that is accessible to patients. The book covers all aspects of infertility from investigation, treatment, successful pregnancy and coping with childlessness. The text is written in a plain-spoken style that is easy to read and absorb, with liberal use of bullet points, diagrams, graphs, photographs, tables and other illustrations. Case studies and patient perspectives are included throughout the text to bring key concepts to life.

Forms of embodied labor, such as surrogacy and participation in clinical trials, are central to biomedical innovation, but they are rarely considered as labor. Melinda Cooper and Catherine Waldby take on that project, analyzing what they call "clinical labor," and asking what such an analysis might indicate about the organization of the bioeconomy and the broader organization of labor and value today. At the same time, they reflect on the challenges that clinical labor might pose to some of the founding assumptions of classical, Marxist, and post-Fordist theories of labor.
Cooper and Waldby examine the rapidly expanding transnational labor markets surrounding assisted reproduction and experimental drug trials. As they discuss, the pharmaceutical industry demands ever greater numbers of trial subjects to meet its innovation imperatives. The assisted reproductive market grows as more and more households look to third-party providers for fertility services and sectors of the biomedical industry seek reproductive tissues rich in stem cells. Cooper and Waldby trace the historical conditions, political economy, and contemporary trajectory of clinical labor. Ultimately, they reveal clinical labor to be emblematic of labor in twenty-first-century neoliberal economies.

Has the college experience of women been an influence on the number of children desired and the number and spacing of their children? Do women come to college with their attitudes and values in this regard already formed? This study of 15,000 women, freshmen and seniors in 45 American colleges and universities, both secular and nonsecular, attempts to answer this question and to determine how such characteristics as religious preference, career intentions, and the number of children in her own family influence a woman's fertility values. Attention is paid to an earlier finding that Catholic college graduates have higher fertility than Catholic high school graduates, although higher education is usually associated with lower fertility. Originally published in 1967. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Why do American couples differ in the number of children they have? To answer this question the first major longitudinal study in American fertility was begun in 1957 with a series of interviews with parents of two children. Family Growth in Metropolitan America (1961) and The Third Child (1963) reported the results of the first two phases of this research project. In this book, in addition to evaluating the longitudinal design of the study, the authors report the results of the third and final interviews, a decade after the first, and attempt to answer such questions as: How well are couples able to predict their own fertility over the years? To what extent does the number of children desired affect the spacing of births? How is fertility affected by peer group relations, by the wife's participation in the labor force, by religion? Originally published in 1971. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Maintaining consistent and reliably high success rates is a daily challenge for every IVF laboratory. This step-by-step guide is an essential aid in navigating the complex maze of physical, chemical, biological, and logistic parameters that underpin successful gamete and embryo culture: temperature, pH, osmolality, gas supplies, air quality, light exposure, infections, managing supplies, personnel, as well as overall quality control. Numerous real-life troubleshooting case reports are presented, identifying all aspects necessary for troubleshooting. Process maps and flow charts accompanying each chapter offer a logical and systematic approach to problem solving in the laboratory. This is an essential resource for scientists in assisted reproductive technology and specialists in reproductive biology and medicine, helping IVF clinics to achieve the dream of every infertile couple: the birth of a healthy child.

How well do you really know your body?

How easy do you think it will be for you to get pregnant - or NOT to get pregnant?

You've probably never really been educated about your reproductive years - perhaps you learnt everything you know from friends, or from the media, or online. You might be ready for a baby now; or, like so many other women, you might want to delay the birth of your first child while you establish your career. Perhaps you're thinking about freezing your eggs.

Professor Joyce Harper is an internationally recognized expert on female fertility and fertility education, and in 12 chapters she covers the full scope of your reproductive years, from your first period to menopausal symptoms. Her straightforward, scientifically based advice will give you all the information you need to make informed decisions about your reproductive choices. Only when you really understand your menstrual cycle works can you optimise your lifestyle to get pregnant successfully - while being properly aware of how and when your fertility will decline.

Your Fertile Years answers all your questions about things like egg freezing and IVF, and debunks not only the myths surrounding fertility treatment, but also the misinformation and scare stories that surround conception and pregnancy, including the bottom line on supplements, diet and holistic therapies.

A shining beacon in the murky fertility landscape, this book will accompany you through your fertile years, giving you the guidance you need to make decisions that work for you, your family, your career and your body.