This extensively updated new edition provides an indispensable account of modern in-vitro fertilization practice, building upon the popularity of previous editions. The authors initially give a comprehensive review of the biology of human gametes and embryos, before outlining basic to advanced IVF techniques. New developments in practical techniques and understanding are discussed, including in-vitro maturation, vitrification, preservation of fertility for cancer patients, stem cell technology, preimplantation genetic testing, and the role of epigenetics and imprinting. The revised introduction also incorporates a 'refresher' study review of fundamental principles of cell and molecular biology, now updated with current knowledge of meiosis in human oocytes, embryo metabolism and basic principles of genome editing. With high-quality illustrations and extensive, up-to-date reading lists, it is a must-have textbook for trainee and practising embryologists, as well as clinicians who are interested in the scientific principles that underpin successful IVF.

Has the college experience of women been an influence on the number of children desired and the number and spacing of their children? Do women come to college with their attitudes and values in this regard already formed? This study of 15,000 women, freshmen and seniors in 45 American colleges and universities, both secular and nonsecular, attempts to answer this question and to determine how such characteristics as religious preference, career intentions, and the number of children in her own family influence a woman's fertility values. Attention is paid to an earlier finding that Catholic college graduates have higher fertility than Catholic high school graduates, although higher education is usually associated with lower fertility. Originally published in 1967. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Why do American couples differ in the number of children they have? To answer this question the first major longitudinal study in American fertility was begun in 1957 with a series of interviews with parents of two children. Family Growth in Metropolitan America (1961) and The Third Child (1963) reported the results of the first two phases of this research project. In this book, in addition to evaluating the longitudinal design of the study, the authors report the results of the third and final interviews, a decade after the first, and attempt to answer such questions as: How well are couples able to predict their own fertility over the years? To what extent does the number of children desired affect the spacing of births? How is fertility affected by peer group relations, by the wife's participation in the labor force, by religion? Originally published in 1971. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

"Original, important, moving, witty and exquisitely-written. WHAT a feat." - BERNARDINE EVARISTO "Incredible... beautiful and funny and humane." - EMILIE PINE "Pristine poetry and prose." KATHERINE MAY, AUTHOR OF WINTERING "Babies who are this small, he says, have a good chance of survival. Small is not good for babies. It is not whimsical or cute or the cause of admiration. It is the first time it occurs to us that they might not survive. Babies die from smallness." Claire Lynch knew that having children with her wife would be complicated but she could never have anticipated the extent to which her life would be redrawn by the process. This dazzling debut begins with the smallest of life's substances, the microscopic cells subdividing in a petri dish in a fertility treatment centre. She moves through her story in incremental yet ever growing steps, from the fingernail-sized pregnancy test result screen which bears two affirmative lines to the premature arrival of her children who have to wear scale-model oxygen masks in their life-saving incubators. Devastatingly poignant and profoundly observant - and funny against the odds - Claire considers whether it is our smallness that makes our lives so big.

An original graphic novel based on the IVF stories of its husband-and-wife authors and the 1-in-50 couples around the world like them. Conrad and Joanne met in their final year of university and have been virtually inseparable since then. For a while, it felt like they had all the time in the world. Yet now, when they are finally ready to have kids, they find that getting pregnant isn't always so easy. Ahead of them lies a difficult, expensive, and emotional journey into the world of assisted fertility, where each 'successful' implantation is followed by a two-week wait to see if the pregnancy takes. Join Joanne and Conrad, their friends, their family, their coworkers, and a stream of expert medical practitioners as they experience the highs and the lows, the tears and the laughter in this sensitive but unflinching portrayal of the hope and heartbreak offered to so many by modern medicine.

In Taking Baby Steps, Jody Lynee Madeira takes readers inside the infertility experience, from dealing with infertility-related emotions through forming treatment relationships with medical professionals to confronting difficult medical decisions. Based on hundreds of interviews, this book investigates how women, men, and medical professionals negotiate infertility's rocky terrain to create life and build families-a journey across personal, medical, legal, and ethical minefields that can test mental and physical health, friendships and marriages, spirituality, and financial security.

Selecting good-quality sperm for use in in-vitro fertilization is a key step in assisted reproduction. For many years purely morphological attributes have been used to assess suitability, but increasingly biochemical and molecular biological techniques are now identifying sperm with the best chances of producing viable and healthy embryos. Focusing on modern sperm function testing, this manual provides technical details of commonly used tests and gives an overview of the laboratory techniques used to evaluate sperm samples. Covering a variety of testing methods in detail, from manual and computer-assisted semen analysis to zona pellucida binding assays, and tests assessing sperm DNA damage such as the TUNEL assay. Describing the underlying science, practical advice for performing the tests is given, including tips for optimizing outcomes and trouble-shooting. This is an essential guide for reproductive medicine specialists, clinical andrologists, urologists and gynecologists working with sub-fertile men.

A comprehensive integrative handbook on fertility treatment, and Assisted Reproduction Techniques (ART), the book is written by specialist contributors for health professionals and Complementary and Alternative Medicine (CAM) practitioners, and for those seriously considering ART themselves. Integrated approaches to infertility offer both a greater awareness and understanding of the combination of factors that can influence the chances of success when undergoing different types of ART. Leading experts review the evidence and discuss the benefits of different approaches to support the physiological and emotional aspects of fertility and fertility treatment. The book covers everything from identifying and treating conditions that may reduce fertility, including immunological abnormalities and specific male and female factors, to how nutrition, acupuncture, reflexology and yoga can support couples going through assisted reproduction, including helping to improve some immunological aspects. There is also a chapter that looks specifically at support for the over 40's.

For around half of the couples who have trouble conceiving the cause of infertility is sperm-related. Intracytoplasmic sperm injection (ICSI) is the most common and successful treatment for male infertility. Here, the pioneers for the technique, along with authorities in the field, describe the underlying science of ICSI and other micromanipulation techniques. Practical advice for performing the techniques is covered in depth, including sperm selection, laser-assisted ICSI, and the use of piezo in ICSI. Examining the safety of ICSI in animal models as well as the impact of ICSI on the health and well-being of the children conceived through the procedure is discussed. This manual is an essential resource for clinical embryologists and laboratory personnel wishing to refine or develop techniques and improve outcomes.

In early 2020, Rosanna Davison gave a raw and sincere account of the 14 miscarriages she had suffered before choosing to have a baby via gestational surrogate. Then, just weeks later, she discovered she was pregnant with identical twin boys, conceived naturally. In this heartfelt and honest book, Rosanna reveals her difficult journey to motherhood and examines the stigma and silence that surrounds infertility. From the anguish of her multiple pregnancy losses to the decision to explore surrogacy, as well as the practical and emotional challenges involved in pursuing this route to parenthood, she reveals what it was like to find out she was expecting miracle twins just months after her daughter was born. She describes how she and her husband have coped with the long and intense road to becoming parents of three children under two. Shining a light on miscarriage and motherhood, Rosanna tells her story.

'This book is an absolute game-changer' - Dr Xand Van Tulleken 'Everyone concerned about their fertility should read this book' - Dr Raj Mathur, Chair of the British Fertility Society The book you can trust to help you achieve a healthy pregnancy. Whether you are trying for a baby now or preparing for a family in future, The Fertility Book is the no-nonsense guide you need to help you to optimize your chances of a healthy pregnancy. World-renowned fertility consultant Adam Balen and reproductive biologist Grace Dugdale dispel the myths in this comprehensive guide to reproductive health, explaining in easy-to-understand terms the genetic and lifestyle factors at play. They take an honest look at the evidence for both conventional and alternative approaches, equipping you with powerful tools to improve your chances of a natural conception and an understanding of how to create the best environment for a healthy pregnancy. If you do decide to seek help through assisted conception, this book will be with you every step of the way, explaining what treatments are available and how to approach them, so that you can come to an informed decision about what is right for you. Professor Adam Balen and Grace Dugdale have decades of experience helping couples on their journey to conception and beyond. Now in this, their first book for a general readership, they explain everything you need to know to understand your own fertility.

The increasing understanding of individual differences in response to in-vitro fertilization (IVF) treatment, resulting from genetic and ethnical differences, has increased the potential for individualized treatment for patients, resulting in improved pregnancy and live-birth outcomes. This illustrated book summarizes, and provides updates on, the most recent developments in individualized infertility treatment and embryo selection techniques. Individualization is not only confined to the different steps in the ovarian stimulation process and the luteal phase support, but also to embryo selection techniques, which include, among others, the analysis of embryo development pattern and genetic testing. Chapters cover a multitude of topics, ranging from oocyte maturation and immunological testing to fertilization technique in the IVF laboratory and preparation for optimal endometrial receptivity in cryo cycles. Essential reading for IVF specialists and embryologists in IVF Clinics and also an important text for medical consultants specializing in reproductive medicine, gynecology and embryology.

Few recent technologies have attracted as much attention as In Vitro Fertilization (IVF), a technique in which ova are fertilized in a glass dish and transferred to the prospective mother. Despite a large body of literature and much recent publicity on the ethics of new re-productive technologies, however, we are far from understanding what actually goes on in the nation's 138 in vitro fertilization centers, and even farther from possessing a clear public policy regarding this controversial technology. In this book the author examines two different, and often opposing worlds of in vitro fertilization: the public's political, legal and ethical concerns surrounding the technique, and the personal, pragmatic world of the individual patients who come to the centers seeding a cure for infertility. The crux of this analysis revolves around the intersection, and sometimes the antagonism, between these two worlds. While use of the centers is growing extremely fast, there is an absence of any federal-level policy to monitor this technique. To fill this vacuum, individual practitioners of IVF and other new reproductive technologies. The author investigates the current effects of these guidelines in interviews with physicians, scientists, policy makers, and patients at IVF centers, and argues that in this case, the public policy we implement should take its direction from the self-regulation that is already occurring on a local level and which is so well-developed that it has in effect taken the place of a formal federal policy. For all those interested in, or contemplating the rapidly growing field of in vitro fertilization, this is an objective analysis which answers many perplexing questions.

The experiences of infertility and childlessness, while not worse than other griefs and disappointments people experience, are nevertheless distinctive in a number of important respects. Unlike other griefs, they often take place in private, with no body, no funeral, and no public acknowledgement of the loss. In her profound and wise theology of childnessness, Emma Nash takes her own story as a starting point, examining several distinctive features of this painful human experience. She asks what biblical and theological resources offer consolation, and what liberative action individuals and churches might take to make an appropriate response. Weaving trauma theology together with personal experience, Nash offers a profound and heartfelt theological reflection which breaks the barriers between pastoral resource and carefully constructed theology.

Approximately five million children have been born worldwide as a result of assisted reproductive technology (ART). These techniques are now practised independently in most of the world's nations. Although the vast majority of ART parents and children are healthy following the procedures involved, there is an imperative to maintain a high standard of practice and monitor outcomes carefully. Interpretation of outcome data is difficult for a variety of reasons. As ART technologies evolve and new variants are established, the need for robust assessment of outcomes increases. This book gives a thorough review of potential complications of ART, with detailed analysis of outcome data for the various conditions described. A worldwide perspective is given throughout, with an international team of chapter authors.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.