Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development > Reproductive medicine > Infertility & fertilization
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Essential IVF - Basic Research and Clinical Applications (Hardcover, 2004 ed.)
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Essential IVF - Basic Research and Clinical Applications (Hardcover, 2004 ed.)
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There is no clearer testament to the importance and efficacy of in
vitro fertilization in the treatmentof the infertilepatient than
the fact that over one million babies have been born since its
clinical introduction in 1978. The successof this
worldwideendeavorhas evolvedto treat some of the formerly most
intractable forms of infertility and requires individuals with
different skills and insights whose activities are often
compartmentalized into clinical, laboratory and research functions.
The intent of Essential lVF is to present current issues in
clinical IVF that encompass the varied activities of those engaged
in this enterprise. By integrating clinical, basic research and
laboratory-related aspects of human reproduction, readers with
diverse interests should obtain a more complete understanding of
the impact, importance and inter-relatedness of each in the
progress of infertility treatment, and an appreciation of whether
emerging technologies will or should contribute to this progress in
the near future. The topics selected for this volume include
research that has begun to explain the origins of differential
follicular, gamete, embryo and uterine competence, and specific
laboratory procedures and protocols that may have important
clinical implications forthe generation ofdevelopmentally viable
embryos. Human embryoresearchoverthe past 25 years has notonly
confirmed that the developmental potential of each embryo is
unique, but more importantly, demonstrated how genetic and
nongenetic factors for sperm and oocyte determineembryo
competencewell before fertilization. Several chapters deal with the
origins of normal and compromised gametes and how those with high
competence can be identified and isolated for fertilization.
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