Handbook of Statistics: Disease Modelling and Public Health, Part B, Volume 37 addresses new challenges in existing and emerging diseases. As a two part volume, this title covers an extensive range of techniques in the field, with this book including chapters on Reaction diffusion equations and their application on bacterial communication, Spike and slab methods in disease modeling, Mathematical modeling of mass screening and parameter estimation, Individual-based and agent-based models for infectious disease transmission and evolution: an overview, and a section on Visual Clustering of Static and Dynamic High Dimensional Data. This volume covers the lack of availability of complete data relating to disease symptoms and disease epidemiology, one of the biggest challenges facing vaccine developers, public health planners, epidemiologists and health sector researchers.

The research and review papers presented in this volume provide an overview of the main issues, findings, and open questions in cutting-edge research on the fields of modeling, optimization and dynamics and their applications to biology, economics, energy, finance, industry, physics and psychology. Given the scientific relevance of the innovative applications and emerging issues they address, the contributions to this volume, written by some of the world's leading experts in mathematics, economics and other applied sciences, will be seminal to future research developments and will spark future works and collaborations. The majority of the papers presented in this volume were written by participants of the 4th International Conference on Dynamics, Games and Science: Decision Models in a Complex Economy (DGS IV), held at the National Distance Education University (UNED) in Madrid, Spain in June 2016 and of the 8th Berkeley Bioeconomy Conference: The Future of Biofuels, held at the UC Berkeley Alumni House in April 2015.

This book is a survey of the research work done by the author over the last 15 years, in collaboration with various eminent mathematicians and climate scientists on the subject of tropical convection and convectively coupled waves. In the areas of climate modelling and climate change science, tropical dynamics and tropical rainfall are among the biggest uncertainties of future projections. This not only puts at risk billions of human beings who populate the tropical continents but it is also of central importance for climate predictions on the global scale. This book aims to introduce the non-expert readers in mathematics and theoretical physics to this fascinating topic in order to attract interest into this difficult and exciting research area. The general thyme revolves around the use of new deterministic and stochastic multi-cloud models for tropical convection and convectively coupled waves. It draws modelling ideas from various areas of mathematics and physics and used in conjunction with state-of-the-art satellite and in-situ observations and detailed numerical simulations. After a review of preliminary material on tropical dynamics and moist thermodynamics, including recent discoveries based on satellite observations as well as Markov chains, the book immerses the reader into the area of models for convection and tropical waves. It begins with basic concepts of linear stability analysis and ends with the use of these models to improve the state-of-the-art global climate models. The book also contains a fair amount of exercises that makes it suitable as a textbook complement on the subject.

This book presents novel research ideas and offers insights into radar system design, artificial intelligence and signal processing applications. Further, it proposes a new concept of antenna spatial polarization characteristics (SPC), suggesting that the antenna polarization is a function of the spatial direction and providing new ideas for radar signal processing (RSP) and anti-jamming. It also discusses the design of an advanced signal-processing algorithm, and proposes new polarimetric and anti-jamming methods using antenna inherent properties. The book helps readers discover the potential of radar information processing and improve its anti-interference and target identification ability. It is of interest to university researchers, radar engineers and graduate students in computer science and electronics who wish to learn the core principles, methods, algorithms, and applications of RSP.

This book presents recent research on the hybridization of intelligent methods, which refers to combining methods to solve complex problems. It discusses hybrid approaches covering different areas of intelligent methods and technologies, such as neural networks, swarm intelligence, machine learning, reinforcement learning, deep learning, agent-based approaches, knowledge-based system and image processing. The book includes extended and revised versions of invited papers presented at the 6th International Workshop on Combinations of Intelligent Methods and Applications (CIMA 2016), held in The Hague, Holland, in August 2016. The book is intended for researchers and practitioners from academia and industry interested in using hybrid methods for solving complex problems.

This book presents a detailed study of the Lanczos potential in general relativity by using tetrad formalisms. It demonstrates that these formalisms offer some simplifications over the tensorial methods, and investigates a general approach to finding the Lanczos potential for algebraic space-time by translating all the tensorial relations concerning the Lanczos potential into the language of tetrad formalisms and using the Newman-Penrose and Geroch-Held-Penrose formalisms. In addition, the book obtains the Lanczos potential for perfect fluid space-time, and applies the results to cosmological models of the universe. In closing, it highlights other methods, apart from tetrad formalisms, for finding the Lanczos potential, as well as further applications of the Newman-Penrose formalism. Given its scope, the book will be of interest to pure mathematicians, theoretical physicists and cosmologists, and will provide common ground for communication among these scientific communities.

Isogeometric analysis (IGA) consists of using the same higher-order and smooth spline functions for the representation of geometry in Computer Aided Design as for the approximation of solution fields in Finite Element Analysis. Now, about fifteen years after its creation, substantial works are being reported in IGA, which make it very competitive in scientific computing. This book provides a contemporary vision of IGA by first discussing the current challenges in achieving a true bridge between design and analysis, then proposing original solutions that answer the issues from an analytical point of view, and, eventually, studying the shape optimization of structures, which is one of the greatest applications of IGA. To handle complex structures, a full analysis-to-optimization framework is developed, based on non-invasive coupling, parallel domain decomposition and immersed geometrical modeling. This seems to be very robust, taking on all of the attractive features of IGA (the design-analysis link, numerical efficiency and natural regularization), giving us the opportunity to explore new types of design.

This book highlights the remarkable importance of special functions, operational calculus, and variational methods. A considerable portion of the book is dedicated to second-order partial differential equations, as they offer mathematical models of various phenomena in physics and engineering. The book provides students and researchers with essential help on key mathematical topics, which are applied to a range of practical problems. These topics were chosen because, after teaching university courses for many years, the authors have found them to be essential, especially in the contexts of technology, engineering and economics. Given the diversity topics included in the book, the presentation of each is limited to the basic notions and results of the respective mathematical domain. Chapter 1 is devoted to complex functions. Here, much emphasis is placed on the theory of holomorphic functions, which facilitate the understanding of the role that the theory of functions of a complex variable plays in mathematical physics, especially in the modeling of plane problems. In addition, the book demonstrates the importance of the theories of special functions, operational calculus, and variational calculus. In the last chapter, the authors discuss the basic elements of one of the most modern areas of mathematics, namely the theory of optimal control.

This book reviews the state of the art in deep learning approaches to high-performance robust disease detection, robust and accurate organ segmentation in medical image computing (radiological and pathological imaging modalities), and the construction and mining of large-scale radiology databases. It particularly focuses on the application of convolutional neural networks, and on recurrent neural networks like LSTM, using numerous practical examples to complement the theory. The book's chief features are as follows: It highlights how deep neural networks can be used to address new questions and protocols, and to tackle current challenges in medical image computing; presents a comprehensive review of the latest research and literature; and describes a range of different methods that employ deep learning for object or landmark detection tasks in 2D and 3D medical imaging. In addition, the book examines a broad selection of techniques for semantic segmentation using deep learning principles in medical imaging; introduces a novel approach to text and image deep embedding for a large-scale chest x-ray image database; and discusses how deep learning relational graphs can be used to organize a sizable collection of radiology findings from real clinical practice, allowing semantic similarity-based retrieval.The intended reader of this edited book is a professional engineer, scientist or a graduate student who is able to comprehend general concepts of image processing, computer vision and medical image analysis. They can apply computer science and mathematical principles into problem solving practices. It may be necessary to have a certain level of familiarity with a number of more advanced subjects: image formation and enhancement, image understanding, visual recognition in medical applications, statistical learning, deep neural networks, structured prediction and image segmentation.

This book addresses the topic of fractional-order modeling of nuclear reactors. Approaching neutron transport in the reactor core as anomalous diffusion, specifically subdiffusion, it starts with the development of fractional-order neutron telegraph equations. Using a systematic approach, the book then examines the development and analysis of various fractional-order models representing nuclear reactor dynamics, ultimately leading to the fractional-order linear and nonlinear control-oriented models. The book utilizes the mathematical tool of fractional calculus, the calculus of derivatives and integrals with arbitrary non-integer orders (real or complex), which has recently been found to provide a more compact and realistic representation to the dynamics of diverse physical systems. Including extensive simulation results and discussing important issues related to the fractional-order modeling of nuclear reactors, the book offers a valuable resource for students and researchers working in the areas of fractional-order modeling and control and nuclear reactor modeling.

This reference provides detailed information which enables you to quickly understand the physics and modeling of mainstream devices. Packed with nearly 1,000 equations and 396 illustrations.

The author introduces the supersymmetric localization technique, a new approach for computing path integrals in quantum field theory on curved space (time) defined with interacting Lagrangian. The author focuses on a particular quantity called the superconformal index (SCI), which is defined by considering the theories on the product space of two spheres and circles, in order to clarify the validity of so-called three-dimensional mirror symmetry, one of the famous duality proposals. In addition to a review of known results, the author presents a new definition of SCI by considering theories on the product space of real-projective space and circles. In this book, he explains the concept of SCI from the point of view of quantum mechanics and gives localization computations by reducing field theoretical computations to many-body quantum mechanics. He applies his new results of SCI with real-projective space to test three-dimensional mirror symmetry, one of the dualities of quantum field theory. Real-projective space is known to be an unorientable surface like the Mobius strip, and there are many exotic effects resulting from Z2 holonomy of the surface. Thanks to these exotic structures, his results provide completely new evidence of three-dimensional mirror symmetry. The equivalence expected from three-dimensional mirror symmetry is transformed into a conjectural non-trivial mathematical identity through the new SCI, and he performs the proof of the identity using a q-binomial formula.

This book summarizes the main advances in the field of nonlinear evolution and pattern formation caused by longwave instabilities in fluids. It will allow readers to master the multiscale asymptotic methods and become familiar with applications of these methods in a variety of physical problems. Longwave instabilities are inherent to a variety of systems in fluid dynamics, geophysics, electrodynamics, biophysics, and many others. The techniques of the derivation of longwave amplitude equations, as well as the analysis of numerous nonlinear equations, are discussed throughout. This book will be of value to researchers and graduate students in applied mathematics, physics, and engineering, in particular within the fields of fluid mechanics, heat and mass transfer theory, and nonlinear dynamics.

This volume gathers contributions in the field of partial differential equations, with a focus on mathematical models in phase transitions, complex fluids and thermomechanics. These contributions are dedicated to Professor Gianni Gilardi on the occasion of his 70th birthday. It particularly develops the following thematic areas: nonlinear dynamic and stationary equations; well-posedness of initial and boundary value problems for systems of PDEs; regularity properties for the solutions; optimal control problems and optimality conditions; feedback stabilization and stability results. Most of the articles are presented in a self-contained manner, and describe new achievements and/or the state of the art in their line of research, providing interested readers with an overview of recent advances and future research directions in PDEs.

This work makes major contributions to the thriving area of social, communication, and distributed networks by introducing novel methodologies and tools toward the study of the evolutionary behaviors of these networks, as well as their computational complexity and rates of convergence. By departing from the classical approaches and results in the literature, this work shows that it is possible to handle more complex and realistic nonlinear models where either the traditional approaches fail or lead to weak results. The author also develops several easily implementable algorithms, delivering excellent performance guarantees while running faster than those that exist in the literature. The study undertaken and the approaches adopted enable the analysis of the evolution of several different types of social and distributed networks, with the potential to apply to and resolve several other outstanding issues in such networks.

This monograph presents urban simulation methods that help in better understanding urban dynamics. Over historical times, cities have progressively absorbed a larger part of human population and will concentrate three quarters of humankind before the end of the century. This "urban transition" that has totally transformed the way we inhabit the planet is globally understood in its socio-economic rationales but is less frequently questioned as a spatio-temporal process. However, the cities, because they are intrinsically linked in a game of competition for resources and development, self organize in "systems of cities" where their future becomes more and more interdependent. The high frequency and intensity of interactions between cities explain that urban systems all over the world exhibit large similarities in their hierarchical and functional structure and rather regular dynamics. They are complex systems whose emergence, structure and further evolution are widely governed by the multiple kinds of interaction that link the various actors and institutions investing in cities their efforts, capital, knowledge and intelligence. Simulation models that reconstruct this dynamics may help in better understanding it and exploring future plausible evolutions of urban systems. This would provide better insight about how societies can manage the ecological transition at local, regional and global scales. The author has developed a series of instruments that greatly improve the techniques of validation for such models of social sciences that can be submitted to many applications in a variety of geographical situations. Examples are given for several BRICS countries, Europe and United States. The target audience primarily comprises research experts in the field of urban dynamics, but the book may also be beneficial for graduate students.

This book introduces methods of robust optimization in multivariate adaptive regression splines (MARS) and Conic MARS in order to handle uncertainty and non-linearity. The proposed techniques are implemented and explained in two-model regulatory systems that can be found in the financial sector and in the contexts of banking, environmental protection, system biology and medicine. The book provides necessary background information on multi-model regulatory networks, optimization and regression. It presents the theory of and approaches to robust (conic) multivariate adaptive regression splines - R(C)MARS - and robust (conic) generalized partial linear models - R(C)GPLM - under polyhedral uncertainty. Further, it introduces spline regression models for multi-model regulatory networks and interprets (C)MARS results based on different datasets for the implementation. It explains robust optimization in these models in terms of both the theory and methodology. In this context it studies R(C)MARS results with different uncertainty scenarios for a numerical example. Lastly, the book demonstrates the implementation of the method in a number of applications from the financial, energy, and environmental sectors, and provides an outlook on future research.

This book explores the ways in which the broad range of technologies that make up the smart city infrastructure can be harnessed to incorporate more playfulness into the day-to-day activities that take place within smart cities, making them not only more efficient but also more enjoyable for the people who live and work within their confines. The book addresses various topics that will be of interest to playable cities stakeholders, including the human-computer interaction and game designer communities, computer scientists researching sensor and actuator technology in public spaces, urban designers, and (hopefully) urban policymakers. This is a follow-up to another book on Playable Cities edited by Anton Nijholt and published in 2017 in the same book series, Gaming Media and Social Effects.

The book presents pedagogical reviews of important topics on high energy physics to the students and researchers in particle physics. The book also discusses topics on the Quark-Gluon plasma, thermal field theory, perturbative quantum chromodynamics, anomalies and cosmology. Students of particle physics need to be well-equipped with basic understanding of many concepts underlying the standard models of particle physics and cosmology. This is particularly true today when experimental results from colliders, such as large hadron collider (LHC) and relativistic heavy ion collider (RHIC), as well as inferences from cosmological observations, are expected to further expand our understanding of particle physics at high energies. This volume is the second in the Surveys in Theoretical High Energy Physics Series (SThEP). Topics covered in this book are based on lectures delivered at the SERC Schools in Theoretical High Energy Physics at the Physical Research Laboratory, Ahmedabad, and the University of Hyderabad.

This book aims to face particles in flows from many different, but essentially interconnected sides and points of view. Thus the selection of authors and topics represented in the chapters, ranges from deep mathematical analysis of the associated models, through the techniques of their numerical solution, towards real applications and physical implications. The scope and structure of the book as well as the selection of authors was motivated by the very successful summer course and workshop "Particles in Flows'' that was held in Prague in the August of 2014. This meeting revealed the need for a book dealing with this specific and challenging multidisciplinary subject, i.e. particles in industrial, environmental and biomedical flows and the combination of fluid mechanics, solid body mechanics with various aspects of specific applications.

This unique volume introduces and discusses the methods of validating computer simulations in scientific research. The core concepts, strategies, and techniques of validation are explained by an international team of pre-eminent authorities, drawing on expertise from various fields ranging from engineering and the physical sciences to the social sciences and history. The work also offers new and original philosophical perspectives on the validation of simulations. Topics and features: introduces the fundamental concepts and principles related to the validation of computer simulations, and examines philosophical frameworks for thinking about validation; provides an overview of the various strategies and techniques available for validating simulations, as well as the preparatory steps that have to be taken prior to validation; describes commonly used reference points and mathematical frameworks applicable to simulation validation; reviews the legal prescriptions, and the administrative and procedural activities related to simulation validation; presents examples of best practice that demonstrate how methods of validation are applied in various disciplines and with different types of simulation models; covers important practical challenges faced by simulation scientists when applying validation methods and techniques; offers a selection of general philosophical reflections that explore the significance of validation from a broader perspective. This truly interdisciplinary handbook will appeal to a broad audience, from professional scientists spanning all natural and social sciences, to young scholars new to research with computer simulations. Philosophers of science, and methodologists seeking to increase their understanding of simulation validation, will also find much to benefit from in the text.

This book gathers the peer-reviewed proceedings of the 12th Annual Meeting of the Bulgarian Section of the Society for Industrial and Applied Mathematics, BGSIAM'17, held in Sofia, Bulgaria, in December 2017. The general theme of BGSIAM'17 was industrial and applied mathematics, with a particular focus on: high-performance computing, numerical methods and algorithms, analysis of partial differential equations and their applications, mathematical biology, control and uncertain systems, stochastic models, molecular dynamics, neural networks, genetic algorithms, metaheuristics for optimization problems, generalized nets, and Big Data.

This proceedings book presents selected contributions from the XVIII Congress of APDIO (the Portuguese Association of Operational Research) held in Valenca on June 28-30, 2017. Prepared by leading Portuguese and international researchers in the field of operations research, it covers a wide range of complex real-world applications of operations research methods using recent theoretical techniques, in order to narrow the gap between academic research and practical applications. Of particular interest are the applications of, nonlinear and mixed-integer programming, data envelopment analysis, clustering techniques, hybrid heuristics, supply chain management, and lot sizing and job scheduling problems. In most chapters, the problems, methods and methodologies described are complemented by supporting figures, tables and algorithms. The XVIII Congress of APDIO marked the 18th installment of the regular biannual meetings of APDIO - the Portuguese Association of Operational Research. The meetings bring together researchers, scholars and practitioners, as well as MSc and PhD students, working in the field of operations research to present and discuss their latest works. The main theme of the latest meeting was Operational Research Pro Bono. Given the breadth of topics covered, the book offers a valuable resource for all researchers, students and practitioners interested in the latest trends in this field.

This handbook serves as a comprehensive, systematic reference to the major mathematical models used in radio engineering and communications, and presents computer simulation algorithms to help the reader estimate parameters of radio systems. It provides the technical details necessary to design and analyze radar, communication, radio navigation, radio control, electronic intelligence and electronic warfare systems. Mathcad routines, cited in the handbook, should help the reader to optimize radar system performance analysis, and can be used to create custom-made software that better answers specific needs.