Evidence-based Nephrology provides students of nephrology and practicing clinicians with a convenient single source of clinical evidence that has been passed through an evidence-based filter. This fully revised second edition incorporates substantial new available data, updated methods of research synthesis, and a renewed focus on consumer engagement in the evaluation and management kidney disease. This updated textbook includes twenty new chapters and three new sections, covering supportive care and patient-centered care and outcomes. In addition, every chapter that was in the first edition has been extensively updated. This new edition covers epidemiology, acute kidney injury, primary diseases of the kidney, secondary diseases of the kidney, chronic kidney disease and complications, hemodialysis, chronic kidney disease stage 5, peritoneal dialysis, supportive care, transplantation, electrolytes and acid-base disorders, and patient centered care and outcomes for both adult and for pediatric patients. Boasting a new co-editor along with several new chapter authors and section editors, Evidence-based Nephrology is now an even better evidence-based nephrology tool, where each chapter provides a clear foundation of the topic that is supported by the best current evidence. This new edition includes broader coverage of the available evidence and addresses crucial clinical questions regarding the treatment and care of people with all stages of chronic kidney disease, including people undergoing any form of dialysis (hemodialysis or peritoneal dialysis), those requiring kidney transplantation and pediatric patients. Evidence-based Nephrology, Second Edition, is a core resource for the evidence-based nephrology practitioner who is otherwise limited by time constraints from researching every question that may arise daily in the care of their patients.

This book is intended for use by nephrologists, internists, hospitals, trainees in these specialties and indeed anyone interested in renal medicine. It contains top-class authoritative and up-to-date reviews by internationally renowned experts coming from some of the best nephrology centres in the world. It covers the diagnosis, causes and management of acute kidney injury. It also includes a discussion of the diagnosis of chronic kidney disease, including the use of simple clinical and laboratory data, imaging, proteinomics and renal biopsy. It reviews the general management of chronic kidney disease, including an in-depth analysis of kidney transplant immunology. This book is therefore a comprehensive, authoritative text with clear explanation of even the most complex topics.

This book provides a concise yet comprehensive overview of acid-base disorders. Each chapter reviews an acid-base disorder, covering pathophysiology, evaluation, and management of the disorder. The chapters also include clinical cases and a Q&A section, based on scenarios and questions that clinicians regularly encounter when treating patients with these disorders. The book concludes with two chapters on acid-based disorders in special patient populations, including critically ill patients, pregnant patients, and surgical patients. Written by an expert in the field, Acid-Base Disorders: Clinical Evaluation and Management is a state-of-the-art resource that should assist clinicians and practitioners in managing patients with acid-base disorders.

This book provides a concise yet comprehensive resource on Diabetic Kidney Disease. Similar to the previous edition, the book reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features, and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are also covered, as well as an overview to the novel approaches being designed by leading researchers in the field. A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease, 2e is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.

This work gives an introduction to all aspects of drug use in renal failure."Introduction to Renal Therapeutics" is an introduction to all aspects of drug use in renal failure. Covering various diseases affecting the kidneys, each chapter discusses the disease process and treatment. It also addresses the role of the pharmacist in patient care. Case studies and questions and answers are included at the end of each chapter.Written by members of the UK Renal Pharmacy Group, this book will be of particular interest to anyone new to, or planning a career in, renal pharmacy. It will also be of interest to nonspecialists who deal with renal patients and to pharmacy students, and to any healthcare professional with an interest in renal medicine.

The book focuses on pharmacological and non-pharmacological approaches of psychiatric syndromes that commonly occur in patients with kidney disease. It specifically reviews principles of psychotherapy and psychopharmacology with an emphasis on organ impairment and drug-drug interactions specific to nephrology. This book also covers issues with medication nonadherence in patients with chronic kidney disease and psychiatric comorbidity, as well as the associated issues in dialysis and renal transplantation. Additionally, chapters cover various other topics addressing an active stance towards health promotion in chronically ill patients, including the critical role of the diet and physical activity. Such advice is often complex and changing depending on the stage of chronic kidney disease and the individual needs of the patient. Written by specialists in the field, Psychonephrology: A Guide to Principles and Practice serves as a valuable reference and teaching tool that provides an opportunity for learning across a rapidly evolving medical field.

This concise book provides an overview of the essential aspects of transplant nephrology. Chapters cover patient evaluation, treatment options, complications and post kidney transplant approaches to various common chronic diseases. The importance of proper immunosuppressants adjustment to improve the graft half-life and overall patient quality of life are also highlighted. Up to date and practical, this book gives nephrologists and providers that treat kidney transplant patients a succinct resource on management.

The first edition of Comorbidities in Chronic Kidney Disease is focused on the main clinical syndromes associated with renal failure. Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are characterized by a wide spectrum of comorbidities, potentially complicating patients clinical outcomes. In this volume, both editor and authors have planned a complete review of the main clinical syndromes associated with renal injury and failure. The first chapter is dedicated to epidemiological aspects of chronic kidney disease, and also introduces risk factors and associated comorbidities. Arterial hypertension and cardiovascular diseases are actually accountable as major risk factors for developing renal disease, and the next chapter is mainly focused on the latest trials in this field. The following chapter is dedicated to pathophysiology, diagnosis and treatment of dyslipidemia and atherosclerosis in patients with declined renal function. The subsequent chapter is exhaustively focused on the clinical features of secondary hyperparathyroidism and the diseases complications on kidneys, bone, vessels and heart, from early laboratory findings to severe vascular and heart valvular calcifications. The section that succeeds reflects on secondary anemia and consequent cardiorenal anemia syndrome with particular attention on the latest treatment schedules. Coronary artery disease is also discussed, especially for those concerned with clinical features and laboratory diagnosis in chronic kidney disease patients with impaired clearance of coronary acute syndrome biomarkers. Cardiorenal syndrome and sudden cardiac death are well-established clinical aspects in CKD patients, and they are discussed both in terms of pathophsysiological and clinical features. The book finally ends with two sections on hepato-renal syndrome and contrast-induced nephropathy (CIN). CIN represents daily challenges for all nephrologists because due to the large amounts of instrumental diagnostic tests and an increasing number of chronic kidney disease patients involved. This volume could be appreciated both by nephrologists and all clinicians involved in chronic patients management due to schematic and practical editing and form.

Despite our efforts at creating clinical performance measures, clinical practice guidelines and intense government regulations, we still have disparities in care, poor outcomes and quality that is inferior to many other nations. Bundling and payment reform challenge the ability to deliver good care to patients even further. Chronic dialysis is at a crossroads. Physicians and providers must incorporate new approaches, reinventing the paradigm of how to plot the course of patient therapy. This book offers new ideas. It is refreshing, timely and engaging, with a wide range of topics by leading authors, each designed to help meet the challenges yet to come.

Uric acid (UA) is an end-product of purine derivatives in human metabolism. Without further metabolism, it is excreted by kidneys and intestinal tract. Its serum concentration is controlled by the balance between production and excretion. High concentration of UA in human body has been discovered to be associated with various diseases, such as gout, hyperuricaemia, Lesch-Nyan disease, obesity, diabetes, high cholesterol, hypertension, kidney disease and heart disease. This book discusses the detection, applications and role in health and disease of uric acid.

This book is a wide-ranging guide to current and emerging applications of ultrasonography within nephrology that aims to provide readers with a sound understanding of the rationale for the use of ultrasound techniques in various disease settings, for example, complications following renal transplantation, arteriovenous fistulas, renal artery stenosis, nonstenotic renal artery pathology, renal vein pathology, aortic disease, and acute renal failure. Particular emphasis is placed on newer applications, such as those involving elastosonography, contrast-enhanced ultrasonography, and color Doppler imaging. There is no doubt that ultrasound techniques can improve the standard of care in nephrology, from vascular access planning to management of uremic complications. Nevertheless, many nephrologists continue to delegate the performance of ultrasonography to radiologists or other colleagues, which is especially regrettable given the advent of affordable, portable ultrasound scanners. This book will be of value for all clinicians interested in the role of ultrasound techniques in nephrology and will be especially useful for nephrologists seeking to incorporate ultrasonography into their practice.

Diabetic Nephropathy (DN) is the leading cause to end-stage renal disease all over the world. Unfortunately, no effective treatment is available to stop its progression. So far, many key issues remain unrevealed in relation to its pathogenesis, new forms of therapy, and complication intervention. In this book, the authors aim to provide updated medical knowledge and practical management strategies to medical professionals who are caring for DN patients based on their ample clinical experiences, strong bench and bedside research background, and tight collaboration with experts in other fields caring for common complications in DN. The authors also want to shed light on the work of bench researchers in fields of DN and its complications from a clinical perspective.

This book is the first title that focuses exclusively on kidney disease and its impact in the cardiac catheterization laboratory. The increasing prevalence of vascular risk factors such as diabetes, obesity and hypertension coupled with increased longevity has resulted in a worldwide epidemic of cardiovascular and chronic kidney disease (CKD). Never has the impact of one organ system on the other been so profound, as in the current context of cardio-renal interactions. The cross talk between the heart and kidneys is highly relevant in the field of interventional cardiology, given the increasing number of trans-catheter procedures being performed in patients with underlying kidney disease. These procedures also have a significant impact on kidney function and require thoughtful interdisciplinary planning by a cardiorenal team, to achieve optimal outcomes This book assembles the collective expertise of several international leaders in the field of interventional cardiology and nephrology to summarize this complex interface. The book is divided into seven sections to comprehensively cover the topic, including sections on best practices with reduction of contrast associated acute kidney injury, cutting edge techniques to minimize kidney risk with complex interventions, impact of transcatheter valvular procedures on kidney function and the utility of cardio-nephrology teams . Less recognized complications with high morbidity such as athero-embolic renal disease are featured prominently, to increase awareness in the interventional cardiology and nephrology communities. This book is a valuable resource for interventional and structural cardiologists, general cardiologists and nephrologists dealing with the significant overlap areas between these two specialties. It is also relevant to medical students, trainee physicians in nephrology and cardiology, advanced care practitioners and nursing personnel in both specialties . Given the major impact of kidney function on outcomes in patients undergoing cardiac procedures, this textbook serves as a focal point to integrate relevant clinical data from both specialties and help interventional cardiologists achieve optimal outcomes, especially in patients with (or at risk for) kidney disease.

This third edition of this text is organized into seven sections that address the educational needs of dietitians around the world who seek current information about nutritional management of chronic kidney disease (CKD). Part I addresses the differences in the epidemiology of CKD and renal replacement therapy worldwide, such as environmental, ethnic, cultural, political and macroeconomic factors. Part II includes a thorough review of the components of the nutrition assessment, which includes information about psychosocial issues affecting nutritional status in kidney disease and drug-nutrient interactions, and parts III and IV review preventative strategies for common disorders associated with CKD such as hypertension, type 2 diabetes, obesity and cardiovascular disease are provided, and current evidence-based treatment recommendations for the nutrition management of non-dialyzed, dialyzed and transplanted adults are addressed. Part V presents the nutritional concerns of CKD populations with special needs (i.e., pregnancy, infancy, childhood, adolescence and the elderly). The nutrition management of other disorders associated with kidney disease are covered in Part VI; these include protein-energy wasting and the inflammatory response, bone and mineral disorders, nephrotic syndrome, nephrolithiasis, and acute kidney injury. Lastly, Part VII is devoted to cutting-edge research on topics of concern in nutrition in kidney disease such as the gut microbiome including pre- and probiotics, appetite regulation, advanced glycation end products, physical activity and structured exercise, and dietary patterns including plant-based diets. When appropriate, the new clinical practice guidelines in nutrition for individuals with CKD are integrated into the chapters. The third edition of Nutrition in Kidney Disease will be a highly informative resource for nephrologists, nutrition scientists, nutritionists, and researchers and students whose research, practice, and education includes nutrition and kidney disease.

For nearly 50 years, Sleisenger & Fordtran's Gastrointestinal and Liver Disease has been the go-to reference for gastroenterology and hepatology residents, fellows, physicians, and the entire GI caregiving team. Now in a fully revised 11th Edition, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with the newest techniques, technologies, and treatments for every clinical challenge you face in gastroenterology and hepatology. A logical organization, more than 1,100 full-color illustrations, and easy-to-use algorithms ensure that you'll quickly and easily find the information you need. Features new and expanded discussions of chronic hepatitis B and C, Helicobacter pylori infection, colorectal cancer prevention through screening and surveillance, biologic agents and novel small molecules to treat and prevent recurrences of inflammatory bowel disease (IBD), gastrointestinal immune and autoimmune diseases, and more. Offers reliable coverage of key topics such as Barrett's esophagus, gut microbiome, enteric microbiota and probiotics, fecal microbiota transplantation, and hepatic, pancreatic, and small bowel transplantation. Provides more quick-reference algorithms that summarize clinical decision making and practical approaches to patient management. Employs a consistent, templated, format throughout for quick retrieval of information. Includes monthly updates online, as well as more than 20 procedural videos. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Handbook of Peritoneal Dialysis Second Edition Steven Guest M.D. This book is a guide to the clinical practice of Peritoneal Dialysis. Chapters provide the core curriculum for expertise in PD therapy and address relevant clinical challenges faced by caregivers. Contained in this Handbook: Peritoneal Membrane Physiology, PET, Modified PET, DATT, Acute and Chronic PD Prescription, Catheters and Placement Techniques, PD Solutions, Infectious and Non-infectious Complications, Fluid Management in PD, PD in the Diabetic and Morbidly Obese Patient, Nutritional and Metabolic Issues in PD, Survival in the PD Population, Setting Up a PD Program / Infrastructure.

The updated 5th edition of the Handbook of Dialysis is full of evidence-based, practical information on all aspects of dialysis training and therapy. Authored by international nephrology experts, each chapter addresses a different area of the clinical realities of patient management. Topics include screening, diagnosis and management of dialysis patients, including diagnostic work-ups, patient safety, and patient monitoring issues in acute dialysis and hemodialysis cases. This is the essential dialysis manual, filled with up-to-date dialysis information, including preparation, procedures, surgery, problems and side-effects. Features:" NEW expanded coverage of vascular access placement and management NEW discussion of urgent start peritoneal dialysis NEW chapter on practical implementation of sorbent dialysis NEW updated section on home and intensive hemodialysis therapies Coverage of topics including: peritoneal dialysis, acute dialysis, hemodiafiltration, home and intensive dialysis, blood-based therapies, the physiology of peritoneal dialysis, diabetes, hypertension, optimal management of anemia, infections, nutrition, mineral bone disorder, and much more! Quick-reference outline format Content illustrated with tables, diagrams and charts Your book purchase includes an eBook version created for Android, iPad, iPhone, iPod touch, PC, & Mac. This eBook features: Complete content with enhanced navigation A powerful search tool that pulls results from content in the book, your notes, and even the web Cross-linked pages, references, and more for easy navigation Highlighting tool for easier reference of key content throughout the text Ability to take and share notes with friends and colleagues Quick-reference tabbing to save your favorite content for future use

Nutritional Management of Renal Disease, Fourth Edition, offers in-depth reviews of the metabolic and nutritional disorders prevalent in patients with renal disease and serves as an in-depth reference source concerning nutrition and kidney disease. This classic translational reference provides correct diagnosis - and therefore correct treatment - of renal, metabolic, and nutritional disorders. Nephrologists, diebetologists, endocrinologists, dieticians, and nutritionists depend on a strong understanding of the molecular basis for the disease. This fourth edition includes thorough new case reports, offering expert advice on how to use the latest research and clinical findings in counseling patients about dietary and lifestyle options. Readers gain insight into which treatments, medications, and diets to use based on the history, progression, and genetic make-up of a patient.

Prostate cancer is the commonest cancer in men. Current treatments include surgery to remove the whole prostate or radiotherapy of the whole prostate. These radical treatments can treat the cancer effectively but often cause unwanted side effects. Meanwhile widespread screening with prostate-specific antigen has led to an increased diagnosis of localised prostate cancer; at the same time, widespread use of abdominal imaging has led to increased detection of renal masses. In response to demand for improved outcomes with reduced side effects, focal therapy has emerged as an important procedure in managing both prostate and renal cancers. It targets individual areas of cancer, reducing unwanted side effects and the amount of damage to collateral tissue. This new method of treatment has major advantages: it involves less radiation, the removal of less tissue and less time spent in hospital. Handbook of Focal Therapy for Prostate and Renal Cancer provides a comprehensive, timely review of targeted ablation methods to treat prostate and renal cancers. It describes the most effective techniques in current practice, with discussion of the selection criteria, ablation technologies and their limitations, and advice on the management of common side effects. The book opens with a summary of the principles of prostate and renal cancer treatment and the mechanisms of focal therapy. Separate sections on prostate and kidney follow, covering the role of focal therapy, side effects and their treatment and follow-up after targeted ablation. Written in a practical, clinically-oriented style, Handbook of Focal Therapy for Prostate and Renal Cancer is the ideal reference for urologists, radiologists and radiation oncologists wishing to employ the latest focal therapy techniques in the care of their patients.

Adenocarcinoma is the predominant malignancy found in the colon and rectum. Colorectal cancer is the third most common cancer diagnosed in the developed world with a high incidence of mortality and morbidity. The average five-year survival rate remains poor at 55%, although the development of new drugs has improved the survival rate of colorectal cancer patients. The prognosis of colorectal cancer remains poor in spite of the development of novel therapeutic strategies. Human colorectal cancer represents a heterogeneous group of diseases, and its molecular classification is increasingly important. Characterization of novel biomarker targets may lead to prolong the survival rate of colorectal cancer. Biomarkers may have a potential role in screening, diagnosis, prognosis and monitoring disease. Mutations in the KRAS gene in ~40% of tumors have been reported to be induced by genetic and epigenetic alterations. This book, comprised of four chapters, introduces recent topics regarding colorectal cancer, and provides recent highlighted information concerning prevention, diagnosis and treatment. This book will be of interest to undergraduate and graduate students, biomedical researchers, and medical doctors focused on the fields of molecular and cellular biology, medical sciences, and clinical challenges.

Selected as a Doody's Core Title for 2022! Concise, readable, practical and well-illustrated, the sixth edition of the Handbook of Kidney Transplantation has been thoroughly updated and revised to reflect the most current knowledge and practice in the field. Ideal for physicians, surgeons, fellows, and nurses who manage kidney transplant patients, it covers everything from treatment options for end-stage renal disease to transplantation, post-operative management and transplant immunology, focusing on every key aspect of the clinical practice of kidney transplantation. Includes new chapters on the Allocation of Deceased Donor Organs and Kidney Transplantation in the Developing World, as well as expanded chapters on living donation and immunosuppressive drugs and protocols. Outlines the major concerns surrounding renal transplantation and the most successful approaches to problems arising in short-term and long-term patient care. Covers immunobiology and immunosuppression, as well as surgery, histocompatibility, and short and long-term follow-up. Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time — providing a seamless reading experience online or offline Powerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooks Multiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive design The ability to highlight text and add notes with one click

Qualifizierte Diagnostik des Urinsediments! Dieses Lehrbuch vermittelt umfassend in Theorie und Praxis die qualifizierte Diagnostik des Urinsediments. Es erklart die Grundlagen der Urinsedimentdiagnostik und gibt daruber hinaus auch versierten Untersuchern zahlreiche Tipps. Exzellente Digitalfotografien in der Hellfeld- und Phasenkontrast-Mikroskopie zeigen eindeutig alle morphologischen Merkmale und unterstutzen das sichere Erkennen und Differenzieren der Bestandteile des Urinsediments. Fur Nephrologen, Urologen, Gynakologen, Internisten, Allgemeinmediziner, Studierende der Medizin, MTLAs und medizinisches Fachpersonal. Die 3. Auflage wurde umfassend aktualisiert, einige Kapitel ganzlich erneuert und durch zahlreiche neue hochaufloesenden mikroskopischen Aufnahmen als auch durch Kurzvideos als Zusatzmaterial erweitert.