Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental interventions. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. The content is structured in six sections. The first deals with ethical, regulatory, and scientific considerations. Chapters in this section include US and international regulatory considerations, and optimization of anesthesia and analgesia. Part two is dedicated to the principles of anesthesia and analgesia with chapters covering topics in a non-species-specific way, but with a slant towards laboratory animals, including relevant pharmacology of the agents. Part three covers Anesthetic equipment and monitoring. Section four deals with periprocedural care including dedicated chapters to the assessment and management of pain in laboratory species. Part five provides practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species. Part six closes the book with special topics covering management of chronic pain, fetus and neonate interventions, considerations for in-vivo imaging and the study of pain. Anesthesia and Analgesia in Laboratory Animals is the complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs, and researchers who utilize animals in biomedical research.

One of the hallmarks of a master surgeon is the ability to navigate a wide variety of inevitable difficult situations in surgery, whether errors in judgment, technical mistakes, or unavoidable outcomes. Under the leadership of series editor Dr. Stephen R. Thompson, the Complications in Orthopaedics series provides real-world guidance on recognizing and avoiding errors, as well as how to "course-correct" during surgery. In this volume, Drs. P. Maxwell Courtney, Yale A. Fillingham, and a team of expert surgeons describe the most common errors and complications of adult reconstruction surgery, focusing on the knee and hip and demonstrating practical solutions that are integral to improving patient outcomes. Covers key topics such as Pain Management Following Total Hip Arthroplasty and Total Knee Arthroplasty, Achieving Balance and Stability During a Total Knee Arthroplasty, Unicompartmental Knee Arthoplasty, Neurovascular Injury in Total Hip Arthroplasty, Post-operative Periprosthetic Fractures in Total Hip Arthroplasty, Hip Preservation: Complications of PAO?, and many more. Describes and offers solutions to the most common or most devastating errors and complications in the practice of adult reconstruction surgery, combining the breadth of knowledge of academic surgeons with the in-the-trenches skills of community surgeons. Uses an easy-to-follow, standardized chapter format that covers preoperative errors, intraoperative issues, and postoperative complications. Includes procedural video clips to reinforce discussions in the text. Features a full-color design with numerous photographs, radiographs, and illustrations. Includes introductory material on relevant anatomy and necessary background information. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book is a comprehensive guide to the latest advances and techniques in vascular and endovascular surgery. Divided into nineteen chapters, the book begins with discussion on translational vascular research, new oral anticoagulants, and statins. The following sections provide detailed explanations of both common and more complex surgical procedures used in the treatment of vascular disorders and diseases. Highly illustrated with nearly 200 clinical images and tables, the book presents the experiences of vascular specialists worldwide. Key Points Comprehensive guide to the latest advances and techniques in vascular and endovascular surgery Covers both common and more complex surgical procedures Includes discussion on translational vascular research, new oral anticoagulants, and statins Highly illustrated with nearly 200 clinical images and tables

"Orthotics: A Comprehensive Clinical Approach" is an innovative and comprehensive new text that provides essential information about contemporary orthoses to guide the student and clinician in prescribing and utilizing these appliances in neuromuscular, musculoskeletal, and integumentary rehabilitation.

Written by recognized authorities in the field, Joan Edelstein, MA, PT, FISPO and Jan Bruckner, PhD, PT, this is a prime resource for practitioners and clinicians.

Individual chapters cover orthoses for the foot, ankle, knee, hip, trunk, neck, shoulder, elbow, wrist, and hand. Orthoses for patients with paraplegia, burns, and soft tissue contractures are detailed and illustrated. Prescription guidelines, evaluation techniques, goal setting, and training procedures are presented.

Each chapter has interesting "thought" questions and case studies to promote clinical reasoning and problem-solving skills. A unique feature of this text is the inclusion of a point-counterpoint discussion to demonstrate how clinicians can manage the same patient in different ways. This approach inspires broader thinking about clinical management.

Ophthalmic Anaesthesia is a new textbook written by an international group of authors who are recognized experts in the fields of anaesthesia and ophthalmology. Covering the entire subspecialty of anaesthesia for surgery of the eye, the book offers chapters on a variety of subjects including: the history of ophthalmic anaesthesia, physiology and pharmacology, anatomy, pre-operative assessment, paediatric anaesthesia, orbital regional anaesthesia, general anaesthesia, complications, high-volume cataract surgery, and future developments. Written by both academicians and experienced clinicians, this is a well-referenced and illustrated text describing the techniques used in the anaesthetic management of patients undergoing the most commonly performed surgical procedures in the world.

From a background in ethnography, Israeli teacher Ben-David aims to understand the meaning of organ donation and transplantation from the perspectives of the three major partners involved: donors, recipients, and the medical teams. The participation of all partners, each with specific interests, enables human organs to become an exchangeable commodity with social significance. Applying the resulting information from her comprehensive study, Ben-David assesses the roles played by life and death in organ donation within the Israeli Jewish community. She also examines issues of social legitimacy connected to organ donation in the Israeli society, institutionalization of transplantations, and transplantation as a trigger for transformation to hero status.

This publication is intended as a guide to common diagnostic, operative and percutaneous techniques used in creating and maintaining vascular access for hemodialysis. When writing the text, the authors have focused on surgeons in training, fellows, interventional radiologists and clinically active nephrologists. Dialysis nurses and other clinicians involved in the care of end stage renal disease and dialysis patients will also greatly benefit from this handbook. This 2nd edition of the text contains expanded sections on ESRD, access surveillance and surgical and diagnostic devices, as well as new sections on peritoneal and dual lumen catheter placement, commonly used drugs and dialysis, hemo- and peritoneal dialysis techniques and CPT and ICD coding for statistical and billing purposes. These changes reflect the highly technical nature of clinical management in this evolving specialty.

In this issue of Thoracic Surgery Clinics, Guest Editor Cherie Erkmen brings considerable expertise to the topic of social disparities in thoracic surgery. Top experts in the field cover key topics such as social disparities in lung cancer, population health, esophageal cancer, benign lung diseases, and more. Provides in-depth, clinical reviews on social disparities in thoracic surgery, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 12 relevant, practice-oriented topics including Social Disparities Database and Big Data; Health Disparities in Recruitment and Enrollment in Research; Social Disparities in Lung Cancer Risk and Screening; and more.

This text, the proceedings of the 32nd International Conference on Transplantation and Clinical Immunology, held in Lyon, France, on May 25-26, 2000, addresses novel issues in terms of changing indications for transplantation in the management of organ failure, whether humans will remain the only source for organ procurement, prospects for engineering in organ replacement, and whether transplantation will remain the most appropriate approach to organ failure. Some promising treatments are approached, such as enzymic and biochemical replacement, gene therapy, tolerance induction, stem cell transplantation, and xenotransplantation. In addition to the constant improvement in conservative management of organ failure in general, ongoing research in selected fields is reported in the proceedings, such as: liver transplantation vs artificial liver; novel dialysis strategies vs evolving immunosuppression in kidney transplantation; islets transplantation and external implantable insulin pumps vs pancreas transplantation in diabetic patients and circulatory assistance and intramyocardial myoblast injection vs heart transplantation. Pivotal experience in selected emerging transplantations is included, that is, small bowel, limb, skin and neuronal transplantation. Such fascinating perspectives raise medical, economical, and ethical problems which are discussed in this book.

Epilepsy surgery is defined as any neurosurgical intervention whose pri- mary objective is to relieve medically intractable epilepsy (European Fed- eration of Neurological Societies Task Force 2000). The aim of epilepsy surgery is to reduce the number and intensity of seizures, minimise neuro- logical morbidity and antiepileptic drug (AED) toxicity, and improve quality of life. By definition, epilepsy surgery does not include normal surgical treatment of intracranial lesions where the primary goal is to di- agnose and possibly remove the pathological target, often an advancing tumour. In these patients, epileptic seizures are only one symptom of the lesion and will be treated concomitantly as part of the procedure. Temporal lobe epilepsy (TLE) is recognised as the most common type of refractory, focal epilepsy. In one third of all cases the neuronal systems responsible for the seizures that characterise this form of epilepsy fail to respond to currently available AEDs (Andermann F 2002). New imaging methods, especially magnetic resonance imaging (MRI), identify localising abnormalities in an increasing proportion of patients with intractable focal epilepsy. Consequently, the accuracy of the preoperative diagnostic pro- cedures has been significantly improved during the last decade; and suit- able candidates for surgery can be selected more reliably. Currently the main resources in most epilepsy surgery centres have been used to evaluate candidates for TLE surgery.

Work related musculoskeletal disorders (WRMSDs) are the leading cause of worker impairment, disability, compensation costs and loss of productivity in industrialized countries. The aging of the workforce and the increased diffusion of physically demanding jobs contribute to the widespread concern about musculoskeletal disorders.
The effective prevention of work related musculoskeletal disorders needs a multidisciplinary approach, drawing together experience from backgrounds in engineering, mechanics, physiology, occupational medicine and psychology; all considered in the context of ergonomics.
This book is a collection of lectures on both back and upper limb musculoskeletal disorders presented at an International Course sponsored by the Nordic Institute for Advanced Training in Occupational Health (NIVA), and the University of Bologna in September 1999. The lectures were given by renowned international researchers on the subject and therefore the book provides a comprehensive overview of all critical issues related to musculoskeletal disorders at work. The book forms an update to the latest research in the field and will interest a wide range of professionals and researchers in ergonomics as well as in the fields from which the material is drawn.
The book covers the main topics addressed in dealing with occupational ergonomics including:
* occupational biomechanics
* physiology
* epidemiology
* psychosocial issues
* medical diagnosis and management
* ergonomic solutions


eBook available with sample pages: 0203484916

This book offers a thorough and accessible look into the importance of recovery in both staying healthy and performing well, and highlights the detrimental effects of underrecovery on physical and mental health. Internationally renowned experts from psychology, physiology, sport medicine, health, and sport science offer interdisciplinary analysis of the effects of underrecovery as well as the use of applied intervention and prevention strategies. Over the last few decades, research in sports has provided numerous studies showing the importance of addressing recovery to find recovery-stress balance and build resources that help prevent illness and promote healthy living and well-being. Each chapter of this volume discusses a specific area of recovery, providing a collection of useful and practical lessons athletes and non-athletes can take forward in their training and beyond. Focusing on both research and applied counseling techniques to discuss recovery as an underestimated factor in physical and mental health, the book aims to enlighten readers on ways to incorporate recovery into their everyday lives to reduce stress and prevent injury. The book is written for the scientific community, applied health scientists, students, and interested readers. It draws on experiences and scientific findings from the field of sport to make them usable for an expanded understanding of recovery in the field of health and related areas such as the workplace.

Despite the significant decline in heart disease mortaht>' rates over the last 25 years, heart failure has remained a significant problem. We are now confronted with large numbers of terminally ill patients for whom conventional therapies for heart failure have been exhausted and for whom repeated hospital visits are necessary. There now is a major thrust towards a management strategy which embraces a comprehensive approach including vigorous preventive measures and earlier surgical interventions. This book outlines the major surgical options for the treatment of heart failure and brings together a very broad base of opinions with contributions from several outstanding individuals. With the improved knowledge and techniques to control rejection, transplantation has become the central pillar in the surgical management of this group of patients. Unfortunately, because of limited donor supply the teclmique cannot be applied to large numbers of patients. A great deal of excitement, however, exists in the potential for xenotransplantation as a supplement to homotransplantation. The use of cardiac assist devices has become a reality with several hundred LVADS and BiVADS implanted throughout the world and cardiac replacement with total artificial hearts continues to be used successfully as a bridge to transplantation. We are on the thieshold of the broad application of assist devices to provide prolonged relief of heart failure and restore patients to an ambulatoiy home environment and hopefully return to the work force in significant numbers.

Attachment of dissimilar materials in engineering and surgical practice is a perennial challenge. Bimaterial attachment sites are common locations for injury, repeated injury, and mechanical failure. Nature presents several highly effective solutions to the challenge of bimaterial attachment that differ from those found in engineering practice. "Structural Interfaces and Attachments in Biology "describes the attachment of dissimilar materials from multiple perspectives. The text will simultaneously elucidate natural bimaterial attachments and outline engineering principles underlying successful attachments to the communities of tissue engineers and surgeons. Included an in-depth analysis of the biology of attachments in the body and mechanisms by which robust attachments are formed, a review of current concepts of attaching dissimilar materials in surgical practice and a discussion of bioengineering approaches that are currently being developed.

When I first proposed this book, one of the hopes was that it would be the stage upon which would be conducted a quiet, well reasoned discussion of the various techniques of stereotactic radio surgery. At that time, there was quite a bit of rancorous debate that tended to obscure the scientific and medical merits of each of the separate methods. At the present time, I am happy to report that the field of stereotactic radiosurgery is much less riven by such inappropriate posturing. The field has taken many steps towards maturity, both technically and medically. In the course of this mat uration process, there have been many grandiose plans and speeches made on behalf of stereotactic radiosurgery. Inevitably, the reality will not live up to the hype, but such is the natural course of devel opment in these sorts of matters. However, even though events may not match our hopes, we should keep in mind the words of Herbert Parker. Recognizing that new modalities for the treatment of cancer do not stand much chance of revolutionary success, nevertheless, he quite correctly pointed out that " . . . with any type of radiatiQn, the margin between success and failure is small. If the chance of success is a little greater . . . thi might well be classed as a great advance. " Mark H."

This concise, educational, and thorough reference will educate women who are contemplating, undergoing, or recovering from plastic surgery. In Outsmarting Mother Nature: A Woman's Complete Guide to Plastic Surgery in the 21st Century, a female plastic surgeon explains all the major procedures in cosmetic surgery, offering frank insights into both physical and psychological issues and expectations. Dr. Iliana Sweis, who not only performs but has undergone cosmetic procedures, details the stages most women will go through from the time they begin to contemplate plastic surgery. The book explains how one can best prepare for a procedure, what to expect during the actual surgery, and how to handle the healing phase. The first several chapters discuss the emotional aspects underlying the desire to undergo plastic surgery, including its social and professional impacts. Each of the subsequent chapters is devoted to individual plastic surgery procedures in significant detail, using a question-and-answer format. Case studies illustrate what cosmetic procedures can, and cannot, accomplish—and the reality checks that need to be in place as part of the decision to proceed.

Destined to be the definitive reference in this complex surgical area, Endoscopic Craniosynostosis Surgery is the first single resource to offer complete coverage of techniques, outcomes, complications, and results when treating patients with craniosynostosis endoscopically. Dr. David F. Jimenez, a pioneer in the field who has developed minimally invasive endoscopic surgeries to treat very young infants with this condition, provides all appropriate data and detailed guidance on every aspect of the management of craniosynostosis using endoscopic techniques. Covers the surgical management of every type of single suture synostosis as well as multiple and complex synostosis. Presents surgical techniques in depth, with a complete review of short- and long-term outcomes and results. Provides detailed information on patient anesthesia and how to set up the operating room for surgery. Includes detailed descriptions of helmets and their management. Features hundreds of radiographs, clinical photos, and procedural illustrations, as well as procedural videos. Discusses complication avoidance, provides surgical pearls throughout, and supplies patient information online. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access bonus images plus all of the text, figures, and references from the book on a variety of devices.

This book offers readers fresh insights on applying Extended Reality to Digital Anatomy, a novel emerging discipline. Indeed, the way professors teach anatomy in classrooms is changing rapidly as novel technology-based approaches become ever more accessible. Recent studies show that Virtual (VR), Augmented (AR), and Mixed-Reality (MR) can improve both retention and learning outcomes. Readers will find relevant tutorials about three-dimensional reconstruction techniques to perform virtual dissections. Several chapters serve as practical manuals for students and trainers in anatomy to refresh or develop their Digital Anatomy skills. We developed this book as a support tool for collaborative efforts around Digital Anatomy, especially in distance learning, international and interdisciplinary contexts. We aim to leverage source material in this book to support new Digital Anatomy courses and syllabi in interdepartmental, interdisciplinary collaborations. Digital Anatomy - Applications of Virtual, Mixed and Augmented Reality provides a valuable tool to foster cross-disciplinary dialogues between anatomists, surgeons, radiologists, clinicians, computer scientists, course designers, and industry practitioners. It is the result of a multidisciplinary exercise and will undoubtedly catalyze new specialties and collaborative Master and Doctoral level courses world-wide. In this perspective, the UNESCO Chair in digital anatomy was created at the Paris Descartes University in 2015 (www.anatomieunesco.org). It aims to federate the education of anatomy around university partners from all over the world, wishing to use these new 3D modeling techniques of the human body.

The mechanical properties of whole bones, bone tissue, and the bone-implant interfaces are as important as their morphological and structural aspects. Mechanical Testing of Bone and the Bone-Implant Interface helps you assess these properties by explaining how to do mechanical testing of bone and the bone-implant interface for bone-related research.
Articles explore the basic mechanical principles of bone-related study and how to conduct mechanical testing of bone specimens. More practical than theoretical, the text includes 42 chapters in three sections that cover mechanical properties of bone, general considerations of mechanical testing, basic facilities and instruments for mechanical testing; mechanical testing procedures on bone tissues; and mechanical testing procedures on the implant-bone interface. There are approximately three hundred illustrations, including line drawings, diagrams, tables, and photographs.
Mechanical Testing of Bone and the Bone-Implant Interface is the most concise, straightforward, and in-depth treatment ever to be published - long needed by the orthopedic and bone research communities.

In this issue of Foot and Ankle Clinics, guest editor Dr. Don Anderson brings his considerable expertise to the topic of Applied Translational Research in Foot and Ankle Surgery. Applied translational research is designed to ensure the highest possible chance of success, and in this issue, top experts in foot and ankle surgery help you produce more meaningful, applicable results that take both safety and efficacy into consideration. Contains 14 practice-oriented topics including utilizing novel in-clinic assessments to identify aberrant foot biomechanics; foot and ankle alignment and biomechanical implications; patient-specific FE analysis of foot and ankle biomechanics; biomechanics of chronic ankle instability; and more. Provides in-depth clinical reviews on applied translational research in foot and ankle surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.