Surgical Anatomy of the Ocular Adnexa is a beautifully and thoughtfully illustrated anatomical text that provides the ophthalmic surgeon or any surgeon working in the eyelid/orbital region with detailed yet concise, easy to read and understand descriptions of the anatomy in any particular region of the eyelid, orbit or nasolacrimal system. Throughout the text are clinical pearls and vignettes to help the reader appreciate why certain anatomical features are important to understand. Key anatomical concepts are highlighted and easy to visualize with real cadaver photos as well as the artists rendition of the same region. This book: - Develops a thorough understanding of the anatomy in the eyelid, orbit, nasolacriaml and periocular regions. - Fosters an appreciation of how knowledge of the anatomy leads to a better understanding of the pathophysiology of various disease processes involving the eyelid, orbit, nasolacrimal and periocular region. - Conveys the importance of anatomy in the surgical approach to various disease processes in the eyelid, orbit, nasolacrimal and periocular regions. This second edition will be an invaluable guidel to all those working in the eyelid, orbital, and nasolacrimal areas including residents, fellows and staff in ophthalmology, otolaryngology/head and neck surgery, plastic surgery and neurosurgeons working in and around the orbit.

While a surgeon many decades agotreated diseases from headtotoe, this concept has evolved, and today some degree of specialization is the rule worldwide. In many countries various boards for sub-specializations are designed, and after a broad training in general surgery, many young surgeons move on further into a specific field. Knowledge of anatomy and precise surgical technique remain the foundation of high quality surgery. A knowledgeable surgeon, equipped with excellent theore- cal and clinical skills, will only be accomplished when he or she masters the - erative techniques of the practice of surgery. The legacy of an academic surgeon or a surgical teacher relies in great part onthe transmission of his or her surgical abilities. Significant influence on the development in esophageal surgery arises from the surgical understanding of the anatomical and functional structures of the esophagus as well as the ongoing developments in the multidisciplinary m- agement in this challenging field of surgery. In bringing forth this atlas, we were motivated by the desire to create a comp- hensive and educational atlas on esophageal diseases, emphasizing all details of pathophysiologies, diagnostic strategies, pre- and postoperative management, and operative techniques covering minimally invasive and open procedures ranging fromstraightforward tomore complex procedures.

Bringing together the most up-to-date research on post-traumatic arthritis (PTA) and its management, this book is a comprehensive presentation of the current thinking on all aspects of the mechanisms of joint injury and subsequent development of PTA. Divided into thematic sections, it includes discussions of the incidence and burden of PTA, both in society at large and in the military population specifically; the relevant experimental work on PTA, from basic science to animal models; peri-articular tissue responses to of joint injury and potential mechanisms of PTA; the current clinical assessment and treatment of common joint injuries leading to PTA; and emerging technologies and treatments for PTA, including biomarkers and stem cell therapies. Taken together, it will be an invaluable resource for orthopedic surgeons, rheumatologists and other joint injury researchers and clinicians.

This new edition presents an authoritative account of the current state of brain biomechanics research for engineers, scientists and medical professionals. Since the first edition in 2011, this topic has unquestionably entered into the mainstream of biomechanical research. The book brings together leading scientists in the diverse fields of anatomy, neuroimaging, image-guided neurosurgery, brain injury, solid and fluid mechanics, mathematical modelling and computer simulation to paint an inclusive picture of the rapidly evolving field. Covering topics from brain anatomy and imaging to sophisticated methods of modeling brain injury and neurosurgery (including the most recent applications of biomechanics to treat epilepsy), to the cutting edge methods in analyzing cerebrospinal fluid and blood flow, this book is the comprehensive reference in the field. Experienced researchers as well as students will find this book useful.

Transplantation is a medically successful and cost-effective way to treat people whose organs have failed-but not enough organs are available to meet demand. Ethics and the Acquisition of Organs is concerned with the major ethical problems raised by policies for acquiring organs. The main topics are the rights of the dead, the role of the family, opt in and opt out systems, the conscription of organs, living organ donation from adults and children, directed donation and priority for donors, and the sale of organs. In this ground-breaking work, T. M. Wilkinson uses concepts from moral and political theory such as autonomy, rights, posthumous interests, justice, and well-being, in a context informed by the clinical, legal, and policy aspects of transplantation. The result is a rigorous philosophical exploration of real problems and options. He argues that the ethics of acquiring organs for transplantation is not only of great intellectual interest, but also of practical importance. As such, this book will be of profit not only to students and academics who work in applied ethics and bioethics, but also to the lawyers, policy-makers, clinicians, and lobby groups interested in transplantation.

Surgery of the Eyelids, Lacrimal System, and Orbit, second edition is a richly illustrated text of oculofacial plastic surgery, with contributions from over 50 nationally and internationally recognized expert authors. Extensively updated from the first edition, this comprehensive text details the evaluation and surgical management of conditions ranging from basic functional eyelid malpositions to complex aesthetic facial reconstructions. It is an excellent resource for those in training as well as seasoned practitioners wanting to be updated on the newest techniques in eyelid, lacrimal, and orbital surgery. The added section in aesthetic surgery includes both surgical and nonsurgical techniques for facial rejuvenation such as botulinum toxin injections, facial fillers, and chemical and laser resurfacing. With over 350 figures, the reader will be able to gain an in-depth understanding and step-by-step instruction of basic and advanced oculofacial plastic surgical procedures. The recognized expert contributing authors provide readers with trusted insight into new and advanced surgical techniques.
The text is intuitively organized into functional sections including eyelid malpositions, eyelid reconstruction, lacrimal surgery, orbital surgery, and aesthetic facial surgery. Topics include eyelid lacerations and acute adnexal trauma, clinical presentation of eyelid lesions, management of periocular neoplasms, reconstruction of the lower eyelid, reconstruction of the upper eyelid, reconstruction of canthal defects, management of entropion and trichiasis, management of ectropion and floppy eyelids, management of blepharoptosis, management of eyelid retraction, management of blepharospasm and hemifacial spasm, management of facial palsy, evaluation of the lacrimal system, management of pediatric nasolacrimal duct obstruction, surgery of the lacrimal system, orbital and periorbital fracture, evaluation & spectrum of orbital disease, surgical exploration of the orbit, surgical decompression of the orbit, optic nerve sheath decompression, management of orbital cellulitis, enucleation and evisceration, orbital Exenteration, complications of the anophthalmic socket, rejuvenation of the forehead and eyebrows, upper eyelid blepharoplasty, lower eyelid and midfacial rejuvenation, chemical and laser resurfacing of the eyelids and face, botulinum toxin injections for facial rhytids, soft tissue fillers for facial aesthetics, and face-lifting techniques.

This is the only guide you need to pass the MRCS Part B OSCE examination. This unique two-volume set includes comprehensive revision notes on all the areas covered in the exam, numerous practice scenarios with model answers in the format they would be encountered in the exam, and essential exam technique tips. Written by a team of editors and authors with extensive experience of the exam and all the recent changes, it broaches topics that can often trip up the candidate, including communication and history-taking skills. Revision is aided by over 130 images and illustrations, as well as boxes highlighting clinical tips and exam hints.
Volume 1 covers basic surgical skills, including peri-operative care, as well as patient safety, history-taking, communication skills, applied surgical sciences and critical care. Practice scenarios and model answers show you exactly how the examiners will expect you to approach the exam.
Volume 2 addresses the stations that exam the four specialty areas: Trunk and Torso; Limbs and Spine; Head and Neck, and Neuroscience. It covers the anatomy, physiology and pathology in each of these four speciality areas along with detailed clinical exam scenarios and a bank of likely clinical questions and model answers.

This is the only guide you need to pass the MRCS Part B OSCE examination. This unique two-volume set includes comprehensive revision notes on all the areas covered in the exam; numerous practice scenarios with model answers in the format they would be encountered in the exam; and essential exam technique tips. Written by a team of editors and authors with extensive experience of the exam and all the recent changes, it broaches topics that can often trip up the candidate, including communication and history-taking skills. Revision is aided by over 130 images and illustrations, as well as boxes highlighting clinical tips and exam hints.
Volume 2 addresses the stations that exam the four specialty areas: Trunk and Torso; Limbs and Spine; Head and Neck, and Neuroscience. It covers the anatomy, physiology and pathology in each of these four speciality areas along with detailed clinical exam scenarios and a bank of likely clinical questions and model answers.

This volume features up-to-date protocols for the isolation, preservation, and validation of various cell sources comprising large and small animal models, examining the impact of cell transplantation on acute and chronic liver diseases. Hepatocyte Transplantation: Methods and Protocols guides readers through laboratory protocols for the generation of humanized livers for the assessment of biological actions in vivo and techniques to monitor cell engraftment after cell transplantation in vivo are described and procedures for computational analyses of hepatocyte transplantation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Hepatocyte Transplantation: Methods and Protocols is an essential resource for researchers and clinicians to assess the biological as well as the therapeutic potential of hepatocyte transplantation.

The book is an update on contentious or unsettled issues concerning invasive diagnostic and therapeutic challenges in cancer and related disorders, focusing on the surgical approach. Topics include recommendations for the best practice in using the surgery safety checklist, surgical strategies in a variety of thoracic cancers, renal cell carcinoma, tumors of parathyroid glands, mesothelioma, and bariatric surgeries. The focus is on the diagnostic and therapeutic challenges of aggressive cancerous entities, choosing the most beneficial modes for optimal outcomes and patient survival. Chapters also address radioimaging and therapy outcomes in different intracranial lesions leading to severe neurological disabilities. The areas of medical practice addressed are still veiled in uncertainty, yet-unresolved pathogenetic background, and have a substantial component of empirical rather than evidence-based clinical approach. Pursuing and sharing new ideas and innovations is essential for improving the management and outcome. The book endeavors to disseminate and deliberate on the latest medical knowledge, studies, and advancements in surgical and diagnostic dealing with cancer. The book is addressed to physicians and surgeons, and all allied health care professionals engaged in patient care and therapy.

Peripheral nerves are biologic wires that convey the desire for motion from brain to muscle, and the experience of touch from skin to brain. When a nerve is cut, the individual fibers, or axons, must regenerate from the site of injury to reconnect with their skin and muscle targets. Nerve regeneration is a process of bewildering complexity that requires the coordinated action of multiple biologic systems. Gene expression within the neuron is altered to support axon growth, regenerating axons must cross the complex environment of the nerve injury and enter pathways that lead to functionally appropriate end organs, Wallerian degeneration clears these pathways of axon debris, and Schwann cells in the distal nerve must produce growth factors to support regeneration. In spite of this complexity, the surgical repair of transected nerve remains a mechanical process that has changed little in the last century, and that restores normal function to only 10% of adults with nerve injuries. Improving the outcome of nerve repair will require close cooperation between surgeon and scientist. Skyrocketing clinical demands on the surgeon and the rapidly increasing sophistication of neuroscience have interacted to form two distinct cultures. Nerve Repair bridges these cultures by providing a translational review of the clinical and basic science relevant to nerve repair. It provides the clinician with an understanding of pertinent research, and the basic scientist with an overview of the clinical manifestations of nerve injury and regeneration. It is also grounded in the history of peripheral nerve surgery and biology so that modern concepts can be understood in the context of their origins.

In Children's Rights Under the Law, Professor Samuel M. Davis examines ways in which the law relates to children, from private law (torts, contracts, property, child labor, and emancipation) to public law (First Amendment rights of children in school, abortion decision-making for children, school discipline, compulsory school attendance, and regulation of obscenity). Professor Davis discusses the major Supreme Court decisions involving the parent-child-state relationship. He describes issues of medical decision-making for children, personal freedoms of children, and property entitlements of children, and addresses issues that arise in the educational context, or "school law." Professor Davis also covers child neglect and abuse, and summarizes major Supreme Court cases in the juvenile justice area, discussing the broad jurisdiction of the juvenile court, arrest and search and seizure as they apply to children, and police interrogation of children. Finally, he examines how some cases are prosecuted as criminal cases in adult court, issues related to the adjudicatory process (akin to the trial in adult court), and issues related to disposition in juvenile court (akin to the sentencing phase of criminal proceedings).

Kidney stone is a significant disease with a 12-15% prevalence in the United States. Patients with a history of stones have a 50% risk of making another stone in 5 years or 80% risk in their lifetime. The goal of this book is to educate the reader on the nuts and bolts of stone disease and to provide new and updated information to help them tackle this painful disease.

The Oxford Desk Reference: Major Trauma is the missing link between basic trauma management and advanced specialist care. Advanced Trauma Life Support courses have revolutionised trauma care in the last 3 decades, but there is little advice for the key decision makers in trauma care once the primary and secondary surveys are complete. This volume is a practical and evidence-based desk reference, giving a comprehensive walk-through from the initial phases of injury, through key decision-making in the resuscitation room, to surgical principles and rehabilitation. Including chapters on damage control, ballistic and blast injuries, and bariatric trauma, this text covers all the main areas of trauma care necessary for the trauma specialist in the 21st Century.
The Oxford Desk Reference emphasises practical help but also covers the evidence and science behind trauma management. It includes the most up-to-date guidance from national bodies making recommendations for trauma care, using an international team of contributing authors. This book will become an essential tool for everyday use in the management of trauma.

This book describes and illustrates an approach to surgery for spinal cord tumors that is based on a refined concept of anatomic compartmentalization. The aim of this approach is to enable maximum preservation of spinal cord function through confinement of the surgical work to the involved compartment or compartments. Importantly, this involvement differs according to tumor type, and the classification favored by the author takes this fully into account. After introductory chapters on epidemiology and pathology, the anatomy of the spinal cord relevant to surgery for spinal cord tumors is discussed in detail and the proposed classification is clearly explained. The surgical approach to each of the identified anatomic compartments is then described, with attention to the roles of intraoperative mapping techniques, diffusion tensor imaging, and electrophysiologic studies in ensuring that spinal cord functions are spared. Examples of the author's experience when applying the proposed approach are presented. The book is meant for neurosurgeons at all levels of experience.

Aimed at consultant colorectal surgeons and those in training who wish to expand their practice into pelvic floor pathology- a complex and developing area of surgery- Pelvic Floor Disorders for the Colorectal Surgeon provides a modern, thought-provoking approach to pelvic floor disorders written by emerging young leaders in the field. These conditions are of high importance and interest to colorectal surgeons, but also gynaecologists, gastroenterologists and general gastrointestinal surgeons.
The layout of the text book is in 3 sections. The first provides an organizational and diagnostic approach to pelvic floor problems that is conceptual in scope, the second details the patho-anatomical and physiological entities that this diagnostic approach will bring to light and describes their management, while the third is more technical, covering key new diagnostic and therapeutic procedures and their results. The textbook aims to encourage the reader to critically analyze some of their own cherished views, and those more widely established, on colorectal pelvic floor practice.

Cracking the Intercollegiate General Surgery FRCS Viva: A Revision Guide 2e provides the framework and knowledge to pass the non-subspecialty sections of the FRCS (General Surgery) viva and clinical examination. This comprehensive and up to date revision text covers all essential topics in critical care, emergency and general surgery as well as research papers, basic statistics and data manipulation for the academic section.This essential revision guide provides you with the vital points for each topic, presented in a concise, structured manner and referenced where appropriate. It is essential reading for anyone preparing for the FRCS General Surgery exam.

Success in any exam requires careful preparation, background reading and, importantly, prior self-assessment. Containing 1000 Single Best Answer (SBA) questions for the MRCS Part A, this book offers surgical trainees a wealth of exam practice, written and edited by expert authors with recent experience of the MRCS syllabus. Get Through MRCS Part A: SBAs covers the entire syllabus, split into sections on pathology, applied surgical anatomy and physiology. Each question is accompanied by a detailed answer together with a road map highlighting important topics. Written by surgeons, for surgeons, working your way through this book is the best practise for your MRCS Part A examination.

This book identifies the 50 key scientific articles in the field of vascular and endovascular surgery. It provides a commentary to each carefully selected paper and explains why these papers are so important, thus providing every surgeon with the foundation stones of knowledge in this fast-moving area. There has been an exponential increase in the volume and quality of published research relating to vascular and endovascular surgery in recent decades. Among thousands of articles, a small fraction is truly "game changing." Such studies form the foundations of vascular surgery today and the selection of papers within this book provide the 50 landmark papers every 21st-century vascular and endovascular surgeon needs to know. A valuable reference not only to the established surgeon, but also to vascular surgery residents and trainees, as well as to more experienced surgeons as they continue to learn new techniques and approaches and to improve their knowledge of vascular disorders and treatments. The papers provide an evidence-based resource for those surgeons preparing for professional exams and may inspire clinicians to produce new research. About the Editors Juan Carlos Jimenez MD, MBA Professor of Surgery Gonda (Goldschmied) Vascular Center David Geffen School of Medicine at UCLA Los Angeles, California Samuel Eric Wilson, MD Distinguished Professor of Surgery and Chair Emeritus University of California Irvine Irvine, California

This text for students and researchers, takes an interdisciplinary approach to describing the chemistry and physics of materials, their biocompatibility, and the consequences of implantation of devices made of these materials into the human body. The reader is introduced to the principles of polymer science and the study of metals, ceramics and composites, and also to the basic biology required to understand the nature of the host-transplant interface. Topics covered in this book include the macromolecular components of cells and tissues, self-assembly processes, biological cascade systems, microscopic structure of cells and tissues, immunology, transplantation biology, and the pathobiology of wound healing. Topics covered in the materials science chapters include the structures and properties of polymers, metals, ceramics and composites, and the processes for forming materials as well as the pathobiology of devices. The final two chapters deal with tissue engineering and the relations between the biology of cells and tissue transplantation, and the engineering of tissue replacements using passaged cells.

Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the multiscale modeling of hemodynamics and their personalization with conventional clinical data. Focusing on three physiological disciplines, readers will learn how to derive a suitable mathematical model and personalize its parameters to account for pathologies and diseases. Written by leading experts, this book mirrors the top trends in mathematical modeling with clinical applications. In addition, the book features the major results of the "Research group in simulation of blood flow and vascular pathologies" at the Institute of Numerical Mathematics of the Russian Academy of Sciences. Two important features distinguish this book from other monographs on numerical methods for biomedical applications. First, the variety of medical disciplines targeted by the mathematical modeling and computer simulations, including cardiology, vascular neurology and oncology. Second, for all mathematical models, the authors consider extensions and parameter tuning that account for vascular pathologies.