With remarkable progress being reported in living donor liver transplants and small bowel transplantation, the 9th Keio International Symposium for Life Sciences and Medicine was auspiciously timed. Titled "Current Issues in Liver/Small Bowel Transplantation," the Tokyo symposium brought together researchers from Japan and other parts of the world. This volume is a compilation of papers from the symposium, organized into five key areas of interest to medical professionals: Technical aspects and physiological problems in split/living donor liver transplantation; Viral hepatitis and liver transplantation; Current status and future prospects in small bowel transplantation; Liver transplantation for malignant hepatic tumors; and Novel strategies in immunosuppression. Containing the most up-to-date information on these vital issues, the book is an essential resource for all researchers and practitioners concerned with liver and small bowel transplantation.

Nineteen cutting-edge articles by leading practitioners review critical issues concerning biocompatible materials-polymers, metals, and other materials-used in or on the human body. Topics range from biopolymers used in controlled release drug delivery systems and synthetic burn-wound dressings to specific orthopedic devices. Each application-oriented article integrates basic science, engineering and medical experience with discussions of quality control. The contributors offer a wealth of valuable data and experience to materials scientists, research engineers, and academic physicians and surgeons. Their many examples provide rich insights into our experience today with a broad spectrum of modern biomaterials applications.

Discover effective, outcome-oriented ways to help CFS patients who have endured useless or inappropriate treatments! From the author: For many years I have viewed brain function as a system of electrochemical impulses continually flashing through the brain. These neural networks can often be modulated fairly simply by 'tuning' them. The point I have been trying to make for many years is that this process may be pharmacologically regulated extremely rapidly in a manner which does not yet seem to be recognized by the medical profession. In this remarkable volume, Dr. Jay A. Goldstein clearly presents both the theoretical and the practical aspects of his revolutionary approach to treating CFS and other conditions that have often been termed psychosomatic. Dr. Goldstein (author of Chronic Fatigue Syndromes: The Limbic Hypothesis and Betrayal by the Brain: The Neurologic Basis of Chronic Fatigue Syndrome, Fibromyalgia Syndrome, and Related Neural Network Disorders) shows how he achieves results for patients with CFS and a variety of other syndromes in days, rather than months or years. This well-referenced book answers questions, from the most basic to the most complex, including: What is neurosomatic medicine? How did Dr. Goldstein come to pioneer and practice this specialty? What abnormalities in brain function produce neurosomatic disorders? How can an understanding of these abnormalities help you provide effective treatment? Why do these treatments sometimes work so rapidly? What is receptor profiling, and how does it indicate the type of receptor dysregulation in an individual patient? In Part I: Inventing Neurosomatic Medicine, Dr. Goldstein describes the remarkable how and why of his life and his development of this new field of medicine, including his clashes with the medical/psychoanalytic establishment. One of the greatest medical innovators of the modern era, Dr. Goldstein has seen over 20,000 CFS patients and has experienced most of the pitfalls that having such a large number of patients entails. He shares his insight on legal issues, such as how to deal with the law and court systems, how to best provide expert testimony, and how to defend against spurious legal actions. In addition, Dr. Goldstein describes how he learned to work effectively outside of the managed care system. In Part II: Society for Neuroscience Conference Proceedings, the author shares his expertise to bring you experimental results and pearls of wisdom relating to neurosomatic medicine from the 28th and 29th Annual Meetings of the Society for Neurosciencethe largest and most important neuroscience conference in the world. Dr. Goldstein sorted through thousands of experiments presented at the conferences to bring you the most relevant findings. Part III: Pathophysiology and Treatment is essential reading for anyone planning to practice neurosomatic medicine. In this section, richly illustrated with over 70 pages of color figures and diagrams that make complicated concepts clear, Dr. Goldstein shares his knowledge about dozens of the agents he uses to help CFS sufferers and others manage their pain, fatigue, and other symptoms. This is information that simply cannot be found anywhere else, and will prove invaluable to all fledgling neurosomatic practitioners. This one-of-a-kind volume is thoughtfully put togetherfrom the extensive list of abbreviations near the beginning to the exhaustive references and an appendix with diagnostic criteria, a treatment algorithm, a medication list of treatment options available now or in the near future, and a checklist of CFS symptoms.

Having been originally introduced as a term to facilitate discussion of a specific group of patients regarded as entering a state of unawareness following coma, the 'Persistent Vegetative State' (PVS) has established itself as an apparently discrete medical condition with clear-cut implications for ethicists and lawyers that exceed any scientifically based understanding. As a consequence of this upgrading, conclusions drawn about the status and hence the management of this uncommon condition have been increasingly extended to other patients with much more common forms of disability. This book traces the origins of prevailing perceptions about PVS and submits these to critical examination. In doing this it comes to the conclusion that inadequate attention has been paid to acknowledging what is not known about affected individuals and that assumptions have consistently come to be traded as facts. Re-examination of the basis of the PVS and the adoption of a more scientific approach is long overdue and is owed to the community at large which has generally been provided by many medical practitioners with a 'dumbed-down' account of the condition. The book will be of interest to philosophers, medical graduates and neuroscientists but is also intended to remain accessible to the general reader with an interest in the wider implications of trends in medical thinking for attitudes towards many classes of patient. It has an extensive bibliography and will be of specific interest to bioethicists and lawyers with professional interests in PVS.

Advances in Cosmetic Surgery reviews the year's most important questions in this fast-changing field. A distinguished editorial board identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in cosmetic surgery bring concepts to a clinical level and explore their everyday impact on patient care. Contains 25 articles on such topics as platelet-rich fibrin (wound healing and aesthetic); high-definition liposuction; non-surgical approaches to the aging neck; non-surgical rhinoplasty; and robotic hair restoration. Provides in-depth, clinical reviews in cosmetic surgery, providing actionable insights for clinical practice. Presents the latest information in the field under the leadership of an experienced editorial team. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

The treatment of end-stage heart failure with advanced surgical therapies has evolved significantly over the last several years and is a dynamic subspecialty within cardiac surgery. "Surgical Treatmentfor Advanced Heart Failure "describes the surgical management of advanced heart failure, including coronary artery revascularization, mitral valve repair, aortic valve replacement, ventricular remodeling, cardiac resynchronization, mechanical circulatory support with short-term devices for acute stabilization, long-term mechanical support as a bridge to transplant and for destination therapy, left ventricular assist devices, complete cardiac replacement with the total artificial heart, and cardiac transplantation. With contributions from a distinguished group of heart failure cardiologists and transplant surgeons, it is an authoritative resource for cardiac surgeons, cardiologists, and surgeons.

Clinical Research Methods for Surgeons is a comprehensive guide for the surgical scientist, and serves as both a critical review of existing literature and a reference guide for clinical research methodologies as they apply to surgery. The text addresses the clinical research questions facing 21st century surgeons, and provides clear direction on how to incorporate sophisticated research techniques into practice. In addition to the surgical generalist, this practical volume is specifically oriented to surgeons who treat unique diseases, yet have no single resource to facilitate clinical research in these specific areas.
This comprehensive and easy-to-use guide encompasses the entire process of clinical study design, application, and assessment. Part One is aimed at the young surgeon about to engage in new studies, and gives a general overview of the infrastructure of clinical research. Parts Two and Three are geared towards experienced investigators interested in pursuing clinical research and surgeons reviewing the literature for practical application. Part Two focuses on study design and related statistical issues, while Part Three is concerned with measuring and assessing the outcome of clinical studies. Part Four presents topics of interest to the active investigator, such as quality of care and cost-effectiveness analyses. Clinical Research Methods for Surgeons is relevant to both beginning investigators and established researchers, and addresses the unique concerns of surgical diseases and acknowledges that they require special approaches to deal with clinical questions.

Featuring 26 chapters by doctors and other researchers, this handbook reviews the basic information and offers specific instructions concerning: informed consent, conscious sedation and monitoring, antibiotic prophylaxis, endoscopic electrosurgery, the benign esophagus, esophageal manometry, pH test

This book covers the basics of evoked spinal cord potentials

(SCPs) with reference to studies in animals. Many illustrations help the reader grasp the neurophysiological and neuropharmacological background of spinal cord functions. Case studies offer insight into monitoring and diagnosing spinal cord dysfunctions and spinal cord diseases. The book is intended for students in clinical neurophysiology, neurosurgery, neurology, orthopedics and neuroanesthesia.

Currently, individuals interested in seeking an in-depth discussion of transplantation immunology must seek individual articles published in several journals, or extrapolate information from various non-transplant immunology textbooks. The purpose of this text is to provide the reader with a single source of information for the basic science of immunobiology of organ transplantation. It is unique that it focuses on immunobiology from the basic research side, with an emphasis on the cellular and molecular levels.
The readers will be physicians, scientists, and graduate students interested and engaged in the study of immunology as it relates to allo- and xenotransplantation. This book is designed to be the reference standard for the immunobiology of transplantation.

This book is written as a reference and guidebook for practicing surgeons, gastroenterologists, and interventional radiologists with an interest in hepatobiliary diseases. It presents a strategy to enhance surgeons practice and the care of patients.

In this issue of Foot and Ankle Clinics, guest editor Dr. Scott Ellis brings his considerable expertise to the topic of Managing Complications of Foot and Ankle Surgery. Top experts in the field cover key topics such as ankle and TTC fusion, complications from lesser toe surgery, ORIF ankle, navicular fracture, ankle instability, Achilles failed repair, and more. Contains 16 relevant, practice-oriented topics including hallux valgus and hallux rigidus; failed Lisfranc/midfoot arthritis/arthrodesis; flatfoot; persistent pain after hindfoot fusion; and more. Provides in-depth clinical reviews on managing complications of foot and ankle surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In 2005, surgeons in France removed part of the face from a cadaver and grafted it onto the head of a 38-year-old woman grossly disfigured by a dog attack. Three years later, in December, 2008, surgeons at the Cleveland Clinic announced they had performed the first U.S. face transplant. Although modern culture is accustomed to pushing medicine and the human body beyond all limits, the world's first partial face transplant and the seven that have followed have caused a stir that still reverberates globally.

This book begins with the story of Isabelle Dinoire, the recipient of the first face transplant, and chronicles her surgery and battles with tissue rejection. Its scope widens with a look at how surgical teams, including three U.S. transplant teams, are in a global race to perform the first full face transplant, and at how medical history has led up to this point--with prior successful transplants ranging from body parts as simple as cornea to those as neurologically complicated as the heart, a hand, and a penis.

The most novel among these surgeries--the face transplant--conjures up particular and expansive psychological issues. Authors Bluhm and Clendenin show how transplant recipients struggle with functional issues including a lifetime of anti-rejection drugs, a danger highlighted by the recent death of the second face transplant patient, in China. But just as challenging in the case of face transplant is the psychological effect on--and potential threat to--identity. Who are you, if suddenly your face--or a significant portion of it--is not what you were born with? What is it like to look in the mirror, and see a face that is not the one you have always had? Dinoire lamented, "It will never be me." That statement is an absolute simplification of the identity issues a face transplant can create, explain the authors. Bluhm and Clendenin show how, across history and media, humankind--via medicine, literature, film, and other media--has dreamed of a day when face transplants would be possible.

With so many disfigurements occurring among the military in Iraq, and experimental face transplants too expensive for implementation in the private sector, it is likely that the U.S. military will take the reins and further face transplant techniques as quickly as possible to serve injured personnel.

In this issue of Dental Clinics, guest editor Dr. Stephanie M. Munz brings her considerable expertise to the topic of Special Care Dentistry. In this issue, top experts in the field focus on the provision of dental care services for people with cognitive, physical, medical, or developmental conditions which can preclude them from receiving routine dental care. Key topics include patients with cleft lip, orofacial pain, and neurosensory disorders, in addition to teledentistry, mentorship, advocacy, and the impact of the COVID pandemic. Contains 11 relevant, practice-oriented topics including dental materials in special care dentistry; the pandemic impact on oral health of patients with special healthcare needs; teledentistry for patient-centered screening and assessment; oral health advocacy over the lifespan for the patient with special healthcare needs; interprofessional collaboration for the patient with special healthcare needs; and more. Provides in-depth clinical reviews on special care dentistry, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

One of the hallmarks of a master surgeon is the ability to navigate a wide variety of inevitable difficult situations in surgery, whether errors in judgment, technical mistakes, or unavoidable outcomes. Under the leadership of series editor Dr. Stephen R. Thompson, the Complications in Orthopaedics series provides real-world guidance on recognizing and avoiding errors, as well as how to "course-correct" during surgery. In this volume, Drs. P. Maxwell Courtney, Yale A. Fillingham, and a team of expert surgeons describe the most common errors and complications of adult reconstruction surgery, focusing on the knee and hip and demonstrating practical solutions that are integral to improving patient outcomes. Covers key topics such as Pain Management Following Total Hip Arthroplasty and Total Knee Arthroplasty, Achieving Balance and Stability During a Total Knee Arthroplasty, Unicompartmental Knee Arthoplasty, Neurovascular Injury in Total Hip Arthroplasty, Post-operative Periprosthetic Fractures in Total Hip Arthroplasty, Hip Preservation: Complications of PAO?, and many more. Describes and offers solutions to the most common or most devastating errors and complications in the practice of adult reconstruction surgery, combining the breadth of knowledge of academic surgeons with the in-the-trenches skills of community surgeons. Uses an easy-to-follow, standardized chapter format that covers preoperative errors, intraoperative issues, and postoperative complications. Includes procedural video clips to reinforce discussions in the text. Features a full-color design with numerous photographs, radiographs, and illustrations. Includes introductory material on relevant anatomy and necessary background information. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

In this issue of Atlas of the Oral and Maxillofacial Surgery Clinics, guest editors Drs. Mark A. Miller and David M. Yates bring their considerable expertise to the topic of Common Procedures in Cleft and Craniofacial Surgery. Articles from top experts in the field include coverage of cleft lip surgery, different surgical approaches to craniosynostosis, and other craniofacial syndromes, as well as reconstruction and bone grafting. Contains 12 relevant, practice-oriented topics including primary cleft lip deformity; cleft nasal deformity; endoscopic approaches to craniosynostosis; open approaches to craniosynostosis; cranial deformities; and more. Provides in-depth clinical reviews on common procedures in cleft and craniofacial surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Thoracic Surgery Clinics, Guest Editor Cherie Erkmen brings considerable expertise to the topic of social disparities in thoracic surgery. Top experts in the field cover key topics such as social disparities in lung cancer, population health, esophageal cancer, benign lung diseases, and more. Provides in-depth, clinical reviews on social disparities in thoracic surgery, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 12 relevant, practice-oriented topics including Social Disparities Database and Big Data; Health Disparities in Recruitment and Enrollment in Research; Social Disparities in Lung Cancer Risk and Screening; and more.

From a background in ethnography, Israeli teacher Ben-David aims to understand the meaning of organ donation and transplantation from the perspectives of the three major partners involved: donors, recipients, and the medical teams. The participation of all partners, each with specific interests, enables human organs to become an exchangeable commodity with social significance. Applying the resulting information from her comprehensive study, Ben-David assesses the roles played by life and death in organ donation within the Israeli Jewish community. She also examines issues of social legitimacy connected to organ donation in the Israeli society, institutionalization of transplantations, and transplantation as a trigger for transformation to hero status.

This publication is intended as a guide to common diagnostic, operative and percutaneous techniques used in creating and maintaining vascular access for hemodialysis. When writing the text, the authors have focused on surgeons in training, fellows, interventional radiologists and clinically active nephrologists. Dialysis nurses and other clinicians involved in the care of end stage renal disease and dialysis patients will also greatly benefit from this handbook. This 2nd edition of the text contains expanded sections on ESRD, access surveillance and surgical and diagnostic devices, as well as new sections on peritoneal and dual lumen catheter placement, commonly used drugs and dialysis, hemo- and peritoneal dialysis techniques and CPT and ICD coding for statistical and billing purposes. These changes reflect the highly technical nature of clinical management in this evolving specialty.

Ophthalmic Anaesthesia is a new textbook written by an international group of authors who are recognized experts in the fields of anaesthesia and ophthalmology. Covering the entire subspecialty of anaesthesia for surgery of the eye, the book offers chapters on a variety of subjects including: the history of ophthalmic anaesthesia, physiology and pharmacology, anatomy, pre-operative assessment, paediatric anaesthesia, orbital regional anaesthesia, general anaesthesia, complications, high-volume cataract surgery, and future developments. Written by both academicians and experienced clinicians, this is a well-referenced and illustrated text describing the techniques used in the anaesthetic management of patients undergoing the most commonly performed surgical procedures in the world.

"Orthotics: A Comprehensive Clinical Approach" is an innovative and comprehensive new text that provides essential information about contemporary orthoses to guide the student and clinician in prescribing and utilizing these appliances in neuromuscular, musculoskeletal, and integumentary rehabilitation.

Written by recognized authorities in the field, Joan Edelstein, MA, PT, FISPO and Jan Bruckner, PhD, PT, this is a prime resource for practitioners and clinicians.

Individual chapters cover orthoses for the foot, ankle, knee, hip, trunk, neck, shoulder, elbow, wrist, and hand. Orthoses for patients with paraplegia, burns, and soft tissue contractures are detailed and illustrated. Prescription guidelines, evaluation techniques, goal setting, and training procedures are presented.

Each chapter has interesting "thought" questions and case studies to promote clinical reasoning and problem-solving skills. A unique feature of this text is the inclusion of a point-counterpoint discussion to demonstrate how clinicians can manage the same patient in different ways. This approach inspires broader thinking about clinical management.