Tumor Neurosurgery provides information on the basic knowledge and clinical management required for optimal care of neurooncology patients. Providing an up-to-date synopsis of the field of tumor neurosurgery, the book covers the most common sites and tumor pathologies encountered by neurosurgeons. The chapters are organized under broad topics, including investigative studies, perioperative care and the role of newer techniques. The clinical management of CNS tumors in adults and children is described, including spinal tumors, both intradural and extradural. This book provides coverage of relevant topics in the field of tumor neurosurgery, for residents and registrars in training, and for recent graduates of training programs.

Ronald Brisman, M.D. This book will discuss three areas where the The multiplicity of procedures with varying neurosurgeon may provide an important degrees of risks and benefits sometimes re contribution to the relief of intractable pain: quires a sequential approach, but always an trigeminal and other facial neuralgias, chronic individual one, matching an appropriate treat noncancer pain, and cancer pain. By one ment plan or procedure for a particular patient intervention, the neurosurgeon often may pro at a specific time in his or her illness. vide long-lasting pain relief. New techniques, The neurosurgical chapters in this book which have developed since the 1970s and represent my experience with several hundred continue to evolve, dominate the neurosur patients during a 12-year period from 1975 gical armamentarium because they are not only through 1987. I have relied heavily on the effective, but safe. These include percutaneous works of others, which have been quoted from radio frequency electrocoagulation for trigem the neurosurgical literature, but this book is inal neuralgia, spinal stimulation for chronic not meant to be encyclopedic. noncancer pain, and intraspinal morphine in At least as important as knowing when to fusion for cancer pain. operate is knowing when not to do so, and this Sometimes a procedure relieves pain but the is particularly true of the treatment of pain. pain recurs; it may be necessary to repeat the Most patients with pain do not require neuro procedure, which in the case of radiofrequency surgical intervention."

Written by world authorities on the subject, this reference comprehensively covers every aspect of colorectal cancer. Addressing the molecular mechanisms, genetics, identification, and therapy of disease, this guide covers new pharmaceutical developments, current screening protocols, and modern methods of disease management by specialists at renowned institutions such as the Royal Marsden Hospital, the Memorial Sloan Kettering Cancer Center, and the Vanderbilt-Ingram Cancer Center.

With a large volume of ultrasound images and teaching videos, Pleural Ultrasound for Clinicians: A Text and E-book is a print and interactive digital resource that provides practical guidance for all those undertaking pleural ultrasound investigations and procedures. With clear, precise instructions for clinical practice, it will help clinicians: Recognise normal anatomy as well as common pleural pathologies Perfect techniques for ultrasound-guided pleural procedures Learn how to choose the correct ultrasound equipment for their department Test their knowledge through the self-assessment and revision sections

This authoritative, highly illustrated text and color atlas provides a systematic guide to commonly performed minor surgical and dermatology procedures. Accompanied by video clips, this critical resource on skin and minor surgery is designed for all trainees and practitioners, including experienced surgeons, dermatologists, family doctors, nurses, and the supporting healthcare team. Divided into four main color-coded sections, the book covers essential background information including postoperative management and aftercare, the key knowledge required for diagnosis and management, and the skills necessary to perform procedures step by step. Comprehensive coverage-Learn to perform a whole range of procedures from small skin surgical procedures to vasectomy Step-by-step techniques-See how to perform each technique with numerous color illustrations, animations and video clips Practical advice, boxes, tables, warnings, and indications of difficulty level-Achieve success and avoid common pitfalls Authoritative yet contemporary-Gain wisdom from this long-established, trusted book brought completely up to date by today's practitioners

1. A guide to managing paediatric surgical patients in a remote and rural setting 2. Includes guidance on differences in presentation and problems relating to the Tropical environment 3. A key resource in understanding paediatric surgical patients needs when being managed remotely

This book explores an innovative study of women who undergo cosmetic study and the doctors who carry it out. It situates cosmetic surgery as a personal choice made by women against the social and cultural reality of the way womens bodies are scrutinised in Western countries.

Providing the most current information on injuries to the head and neck sustained by young athletes, this practical text presents a thorough review of the complex and emerging issues for youths and adolescents involved in contact/collision sports. While concussions are among the most common injuries, fractures of the skull and facial bones and structural brain injuries can be serious and are discussed in chapters of their own, as are stingers and other cervical spine and cord issues and disease. Injuries to the eyes, ears and jaw are likewise examined. Prevention is a major theme throughout the book, as seen in chapters on protective head- and neckwear, transportation of injured players, and sideline response and return-to-play. Head and Neck Injuries in Young Athletes will be an excellent resource not only for orthopedists and sports medicine specialists treating growing athletes, but also specialists and team physicians who are on the scene at sporting events where these injuries may occur.

This book describes the surgical bariatric procedures most frequently performed worldwide and examines their evolution in recent years both within Italy and internationally. For each operation, indications, the surgical technique, potential complications, and the outcomes with respect to weight and obesity-associated comorbidities are presented. In view of the significant failure rate revealed by studies on the long-term results of bariatric surgery, the problem of weight regain and revision surgery are also discussed in detail, covering the different types of revision, conversion to other procedures, and the main outcomes. In addition, individual chapters focus on selected topics of importance. The role of bariatric surgery in the cure of type 2 diabetes ("diabetes surgery") is discussed and the debate over the significance of gastroesophageal reflux disease and hiatal hernia for choice of procedure is summarized. Finally, the most common endoluminal procedures, which have been gaining in importance, are described and other bariatric operations, outlined.

This is an interdisciplinary book which for the first time assembles the wide spectrum of information on the basic and clinical aspects of the natural anti-Gal antibody, the alpha-gal epitope and the enzyme producing it, alpha-1,3-galactosyltransferase. Anti-Gal is the most abundant antibody in humans, apes and Old World monkeys (monkeys of Asia and Africa). It binds specifically to the alpha-gal epitope (Galalpha1-3Galbeta1-4GlcNAc-R) on glycoproteins and glycolipids. Humans, apes and Old World monkeys lack alpha-gal epitopes. In contrast, the alpha-gal epitope is produced in large amounts on cells of nonprimate mammals prosimians and New World monkeys (monkeys of South America), by the glycosylation enzyme alpha-1,3-galactosyltransferase. This differential distribution of the alpha-gal epitope and anti-Gal in mammals is the result of an evolutionary selective process which led to the inactivation of alpha-1,3-galactosyltransferase in ancestral Old World primates. A direct outcome of this event is the present rejection of xenografts such as pig organs in humans and monkeys because of the binding of human anti-Gal to alpha-gal epitopes on pig cells. The various chapters in this book were contributed by researchers studying basic and clinically related aspects of this area. The book aims to provide comprehensive and updated information on this antigen/antibody system, which at present is the major obstacle in xenotransplantation, and on some of the genetic engineering approaches developed for overcoming this obstacle. In addition, this book describes the significance of anti-Gal and alpha-gal epitopes in some parasitic, bacterial and viral infections, as well as in the pathogenesis ofautoimmune diseases such as Graves' disease. Finally, this book describes novel approaches for exploiting the natural anti-Gal antibody for increasing immunogenicity of cancer and viral vaccines in humans. This book is edited and partly written by Dr. Uri Galili who originally discovered anti-Gal and the unique evolution of &agr;-1,3-galactosyltransferase, and by Dr. Jose-Luis Avila who has been studying anti-Gal significance in Chagas' disease and in Leishmania infections. This book covers the main areas of research on &agr;-1,3galactosyltransferase, its product the &agr;-gal epitope (Gal&agr;1-3Gal&bgr;1-4GlcNAc-R) and the natural anti-Gal antibody that interacts with this epitope. The book includes chapters on: The evolution of &agr;-1,3 galactosyltransferase in mammals; the structure of the &agr;-1,3galactosyltransferase gene; the structure function relationship of the &agr; 1,3galactosyltransferase enzyme; the molecular characteristics of &agr;-gal epitopes on glycolipids and glycoproteins and methods for its detection; the natural anti-Gal antibody and its significance in xenotransplantation; attempts to prevent xenograft rejection by elimination of &agr;-1,3galactosyltransferase gene, and by modulating &agr;-gal epitope expression and anti-Gal activity; significance of anti-Gal and &agr;-gal epitopes in viral, bacterial and protozoal infections; and the possible clinical exploitation of anti-Gal for the enhancement of cancer and viral vaccine immunogenicity.

Adventure and extreme sports are increasing in popularity and it is not surprising that commercial adventure tourism and the accompanying life style and fashion, have become increasingly important to world economy. These unique sports involve not only major physical endurance and mental challenges but interaction and bonding with nature. They also tend to attract and excite audiences, both at the event and in the media. They are exciting to watch and redraw the boundaries of human achievement with the accompanying risks of injury and death. Adventure sports are usually performed in beautiful, exciting and remote locations or in extreme environments far away from medical assistance. Extreme sports usually involve an element of increased risk. These risks are highlighted by the media, usually after a reported accident or fatality but may vary according to the involvement of the participant; the weekend recreational adventure sports athlete or the experienced professional. A wide variety of sports fall into the category of adventure and extreme sports and with an increasing number of disciplines, this field is ever expanding. Sports are performed in contact with the "ground"; mountain running and biking, rock climbing, ice climbing and mountaineering. In the air: skydiving and base jumping. On water: surfing, white water kayaking and rafting, board sailing and diving. And also involve mechanical vehicles and animals! Some sports may be performed as a combination of few disciplines, such as water and air, e.g. kite surfing, and as so involve very unique mechanisms of injury. Sports events can also be merged to form a multi-sport race comprising many disciplines lastly from single to multi day races. Sports may involve competition with others, against the environment or with oneself, frequently the most ferocious adversary. Adventure sports are becoming increasingly popular in the general public and a few take these sports to an extreme level with the accompanying risks. Those that do, bring such time and dedication that they become professional in terms of training, preparation and finance. More and more people are enjoying adventure sports and unfortunately increased numbers are becoming injured as a result. Future research is progressing alongside the sport development, to allow the sport mechanisms, injury patterns and predisposing factors to be better understood. It is the hope of all researchers to make the sports safer without detracting from their adventurous nature. The aim and scope of our book would be to bring the sports medicine involved ineach of these sports into one volume. We would explain each sport including subtle similarities and differences, the common injury mechanisms, patterns of injury and treatment options. Additional chapters would include the mental characteristics of adventure racers and extreme sports athletes, together with the complexities of competing in hot and cold extreme environments. The book will present chapters focussing on the sports listed below, concentrating on published literature and newly formed studies by experts in the fields of injury epidemiology, prevention, management and rehabilitation.

This is a user-friendly reference on all aspects of office-based anorectal surgery for general surgeons and surgeons in training. Well-illustrated, this practical manual shows step-by-step procedures for commonly performed anorectal procedures. The book includes ancillary considerations of ambulatory surgery with timely chapters on set-up of the facility, anesthetic considerations, selection of patients, pre-op and post-op management, nursing aspects, and coding and billing.

The new age of biologic treatment of the ACL is coming. In The ACL Handbook: Knee Biology, Mechanics, and Treatment, the authors cover the past and current state of ACL injuries and treatment, and then introduce and explain the key concepts for understanding the new biologic approach to ACL treatment. The use of factors to enhance graft healing are reviewed, as well as an in-depth review of the science of platelet-rich plasma and its cellular components (platelets, white cells, and plasma). Chapters on in vitro models for science as well as the advantages and disadvantages of animal models for ACL research are included, as are chapters on the new technique of bio-enhanced ACL repair. All are discussed in easily readable text aimed at anyone with an interest of what is coming next in ACL surgery.

This book is designed for anyone involved in surgical education. While it is intended as a core reference for surgeons who want to develop their surgical education knowledge and practice, it also a valuable resource for anyone undertaking a higher degree in health professions education. Divided into five parts, it starts with chapters on foundational knowledge, exploring the past before documenting the current state of surgical education and highlighting various educational leadership and governance topics. The second part examines a range of theories that inform surgical education - cognitive, behavioural and social, while the third part offers practical guidance on elements of surgical education - curriculum design, selection, feedback, assessment, evaluation, simulation and managing trainee underperformance. It also includes chapters on supporting the development of psychomotor skills, operative skills in theatre, professionalism, teamwork and patient safety. The next part shifts the focus to research in surgical education, introducing readers to all phases of conducting education research based on qualitative, quantitative and mixed methods paradigms. The final part looks to the future of surgical education and of surgical educators. Assembling these topics in one volume makes this book invaluable to anyone involved in surgical education.

This text provides a comprehensive and contemporary overview of surgical approaches to lesions of the posterior fossa. It will serve as a resource for neurosurgeons and otologists who treat patients with tumors and vascular diseases of the posterior fossa. It provides a concise review of surgical strategies that address the most important pathologies affecting the posterior fossa. It is richly illustrated with photographs and illustrations of the surgical strategies covered. All chapters are written by experts with world-wide recognition for their contributions in their respective subspecialty. Skull Base Surgery of the Posterior Fossa will be of great utility to Neurosurgeons, Otolaryngologists, and Radiation Therapists with an interest in diseases that affect the posterior fossa, as well as Senior Residents in Neurosurgery and Otolaryngology, and Fellows of Skull Base Surgery and Otology.

Soft tissue tumours are extremely common although difficult to understand due to a large number of sub-types, leading to a significant increase in their imaging in the last decade. This highly illustrated practical book provides a simplified, systematic approach to imaging, reporting and diagnosing these tumours. It covers all the modalities with emphasis on ultrasound and MRI, along with the newer techniques in these modalities. This concise guide to soft tissue lesions, will help clinicians to quickly understand the spectrum of tumours and identify the appropriate imaging techniques to best serve their patients. Key Features: * Provides guidance by international experts on various types of soft tissue tumours (benign, malignant and tumour mimics), their relevant imaging features to help suggest specific or differential diagnosis and when to biopsy and when to refer to specialist centres. * Proves to be an excellent resource for general and specialist radiologists, radiology trainees, sonographers, sarcoma surgeons and oncologists for day-to-day reporting. * Discusses the importance of proper imaging and biopsy of tumors and the implications of unplanned excisions in sarcoma.

This handy guide is packed full of information to support medical students, junior doctors and other health professionals in making an accurate diagnosis in relation to different presenting complaints. Now in its fifth edition, the Pocketbook takes the reader through the key steps of narrowing a differential diagnosis, including history, examination and investigation findings. It has been fully updated to cover the full range of common presenting problems facing clinicians today. This book is easy-to-read and logical, making it useful for all clinicians within a variety of settings, from the classroom to emergency department and primary care. This Fifth Edition covers 125 common presenting problems in both medicine and surgery in a consistent format. Each topic includes a list of all potential causes of the condition, colour coded to indicate common, occasional or rare causes. Important geographical variations are also highlighted. Two sections cover the differential diagnosis of biochemical and haematological disorders which provide a ready check when reviewing abnormal results The text includes a targeted guide to the relevant general and specific follow-up investigations which should be carried out as appropriate. Each topic ends with a box highlighting important learning points, or indicating symptom and signs suggestive of significant pathology which require urgent action. A new authorial team have thoroughly revised the contents and ensured the coverage is entirely appropriate for the book's readership.

Immunosuppression in solid organ transplantation is experiencing a worldwide revival since new drugs are now available in the late-1990s and others are under development. In order to contribute to the design of future strategies, a critical approach of surrogate endpoints is given and long-term side effects are analyzed, together with the impact of non-compliance, quality-of-life and economical parameters. In this book, international specialists have set up the scientific rationale and provided new bases for further immunosuppressive strategies.

An ever-increasing number of surgical procedures are now being performed in ambulatory settings. Hospital beds are at a premium and resources are becoming scarcer. This atlas guides readers through all the practicalities: it looks at the potential of short-stay surgery, how to set it up and how it may be relevant to all surgical specialities. Specialists well- known in their sphere discuss and illustrate operations that can be performed without a stay in hospital. The topics covered will become more and more relevant as time goes by, and those who read this book will be able to stay well ahead of the game. It is designed to help surgeons plan for the future and discover the vast potential for this form of surgery.

Thanks to the advent of leading-edge technologies, there is a new cross-sectional field of surgery: robotic surgery. Due to the rapid development of robotic surgery systems such as da Vinci, there is a great need to refresh one's knowledge every day. This book covers all surgical areas: urological surgery, digestive surgery, and cardiac surgery in addition to mitral valvular disease. It also summarizes the most current topics in robotic surgery addressed by well-known experts from around the world. These specialists' expertise provides useful insights into modern educational techniques for the latest trends in surgery-knowledge that will be valuable to students, residents, and experts who are eager to learn more about advanced medical care including da Vinci as a cross- cutting surgical device, even if it lies outside their specialty field.

The topic of heart failure although extensively researched and reported, has several gray areas. This is especially seen in determining strategies for combating advanced heart failure. The global burden of ischemic heart disease is increasing at an alarming rate to almost pandemic proportions. Even in the presence of state-of the art technology for prompt and successful coronary reperfusion, the population progressing to ischemic cardiomyopathy is substantial. The treatment strategies for ischemic cardiomyopathy do not always ensure optimal clinical results, the reasons for which are varied. The proper patient selection is vital as is the tailoring of suitable therapy. The approach is thus multi-pronged, of which surgical ventricular restoration (SVR) has a definite role. Despite various randomized studies like the STICH-hypothesis 2, where there was a huge selection bias, with patients subjected to an erroneous technique of SVR, with inadequate ventricular remodelling assessment. The present need is to understand the unique anatomy of the left ventricle, its function and perturbations with the onset of heart failure, in order to plan therapeutic strategies to restore near normal anatomy and function. A study of the hemodynamics in ischemic cardiomyopathy is essential, as it differs in certain aspects from other causes of heart failure like idiopathic dilated cardiomyopathy and valvular heart diseases. Since information on these aspects are scattered in various scholarly articles, a concise source in the form of a book would be appropriate and useful for both cardiologists and cardiac surgeons. This project represents a concise review of normal and abnormal cardiac anatomy and physiology, the evolution of SVR to EVLPP with validation of near normal ventricular restoration, plus act as a reference guide for cardiac surgeons with interest in SVR.