The Trauma Care Manual 3e is the definitive evidence-based manual of best trauma practice. Now in its third edition, this valuable book continues to provide clear practical guidelines for the management of victims of major trauma. New coverage includes chapters on abdominal and urological trauma, aswell as trauma in the obese patient. Also included is coverage of pre-hospital management; trauma centres, sytems & teams; modern trauma resuscitation; trauma physiology & metabolism; damage control surgery. Written by members of Trauma Care, this book offers a nationally accepted set of standards for good practice.

This book provides surgeons and gastroenterologists with state-of-the-art techniques in terms of advanced colonoscopy. Chapters introduce methods of removing polyps that were not previously amenable to colonoscopic snare polypectomy. Advanced techniques such as closure of perforations and intestinal stenting are extensively covered. The text maintains a strong emphasis on surgical/endoscopic technique. Extensive discussion on equipment and skill acquisition is also covered. As many readers will never have seen these complex procedures before, extensive photographs and video clips are provided. The authors provide tips, tricks, and pitfalls that will help the reader incorporate these new techniques into their practice. Advanced Colonoscopy: Polypectomy and Beyond will be of great value to any surgeon or gastroenterologist currently performing colonoscopy and interested in advanced techniques.

This atlas is a comprehensive guide to the treatment and correction of scars. It is divided into four sections covering the different types of scar: atrophic and stretch marks, keloid and hypertrophic, normotrophic, and mixed. For each scar type, the various invasive and minimally invasive procedures and their results are documented with the aid of numerous high-quality photographs. In the section on keloid and hypertrophic scars, treatment is presented according to scar localization. In addition, the influence of etiology on treatment is considered, with distinction between scars due to injuries, animal bites, inflammatory diseases (including acne and varicella), and burns. Care is taken to distinguish between approaches suitable for fresh scars (in the inflammation, proliferation, and maturation phases) and those appropriate for scars present for more than one year. Potential adverse effects and complications of treatment are also explored. "

This book charts the history of the worldwide introduction of an operative treatment method for broken bones, osteosynthesis, by a Swiss-based association, called AO. The success of the close cooperation between the AO's surgeons, scientists and manufacturers in establishing a complicated and risky technique as a standard treatment sheds light on the mechanisms of medical innovation at the crossroads of surgery, science and industry and the nature of modern medicine in general.

Modern imaging methods have made it possible to detect breast cancer at an earlier stage than in the past. Nevertheless, a large majority of suspicious findings at screening subsequently prove to be benign. It is therefore important to be able to identify benign lesions in a manner that is reliable, tissue sparing, patient friendly, and cost-effective. More than 70% of breast biopsies can now be performed using minimally invasive procedures that meet these criteria. This book examines in detail vacuum-assisted minimally invasive breast biopsy systems (ATEC, EnCor, Intact, Mammotome and Vacora), stereotactic systems, MRI-guided procedures, and ductoscopy. Further chapters are devoted to the pathology of the breast tissue obtained using these procedures, their limitations, the implications of recent advances in breast imaging, and the results of cost-benefit analyses. The closing chapter provides a systematic review and meta-analysis of recent data.

This book summarizes rapid progress and innovation in transplantation and regenerative medicine - the merger of reconstructive plastic surgery and transplantation - called Vascularized Composite Allotransplantation. This merger includes face, hand, uteri, larynx, tongue, penis and trachea translplantations as well as other body part transplants using grafts derived from organ donors. These sorts of transplants are now performed more commonly. Cell therapies for immunomodulation are surrogates for immune responses after transplantation to non-invasive imaging of neuroregeneration for improving functional outcomes after transplant.

As an addition to the European postgraduate training system for young neurosurgeons, we began to publish in 1974 this series of Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Neurosurgical Societies. This series was first discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the series being Jean Brihaye, Bernard Pertuiset, Fritz Loew and Hugo Krayenbuhl. Thus were established the principles of European co operation which have been born from the European spirit, flourished in the European Association, and have been associated throughout with this senes. The fact that the English language is now the international medium for communication at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contri butions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publication of any volume for scrutiny and suggestions for revision. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the first part of each volume.

The Hip Joint, written in 2016, provides a detailed account of the hip joint's anatomy and biomechanics and covers recent trends in orthopaedic surgery of the hip joint, including the latest advances in revision total hip arthroplasty (THA), computer-assisted navigation for THA, resurfacing of the hip joint and neoplastic conditions around the hip as well as indications, complications and outcomes of hip arthroscopy. Another book, The Hip Joint in Adults: Advances and Developments, gives additional important details of how hip joint surgery has evolved around the world. While much of the basic knowledge in this area is constant, it is critically important to stay current on those areas that do change. This updated second edition of The Hip Joint contains a host of original articles from contributory authors all around the world, showing the evolution of the hip joint till the present day, building upon the solid foundation set by the first edition. It covers hot topics such as 3D printing in orthopaedics and traumatology, stem cell therapy in orthopaedics, hip resurfacing, hip-preserving surgery, sports medicine for the hip joint, robotic-assisted surgery in orthopaedics and neoplastic conditions around the hip.

The latest edition of this text provides a comprehensive overview of the "natural flow of knowledge" regarding inflammatory bowel disease, with an emphasis on state-of-the art approaches that should be the basis for diagnosis and treatment of most patients. In addition to updated chapters, this volume includes new chapters on such topics as the impending biosimilar revolution, quality of care, and new challenges to previously held beliefs about IBD diagnosis, treatment, and pathogenesis. The book is also one of the first to have a chapter written specifically by and for physician extenders in the training of colleagues and the treatment of patients, which is of increasing importance moving forward in the medical profession. Written by experts in the field, Inflammatory Bowel Disease: Diagnosis and Therapeutics, Third Edition is a valuable resource for physicians, nurses, researchers, and other health care providers interested in the latest cutting-edge knowledge for treating patients with inflammatory bowel disease.

This book provides clear instruction on the surgical treatment of joint problems in adult hemophilia patients. The procedures applicable to specific joints, including the shoulder, elbow, hip, knee and ankle, are carefully reviewed with the aid of high-quality illustrations. The surgical treatment of articular hemophilic pseudotumors and bone cysts is also considered. In addition, clinically relevant information is provided on a range of topics, such as the treatment of hemophilic hemarthrosis, the imaging of hemophilic joints, hematological perioperative management, anesthesia, rehabilitation and pharmacoeconomics. Finally, the controversial issues of postoperative thromboembolic prophylaxis and the role of COX-2 inhibitors in hemophiliacs are reviewed. The guidance provided draws on both the authors' extensive personal experience and an in-depth review of the pertinent literature. The book offers an excellent, up-to-date account of knowledge on musculoskeletal problems and approaches to joint surgery in adults with hemophilia. It will be of value to orthopedic surgeons, rehabilitation physicians, hematologists, radiologists and pharmacy researchers.

The international symposium "Syringomyelia 2000" in Kobe, Japan, brought together experts in neurosurgery, neurology, and neuropathology. The decade leading up to this event saw remarkable developments in surgery and imaging technology. The symposium was thus an opportunity for researchers and clinicians to enhance and broaden the scope of their knowledge and to become more aware of work being done in complementary fields. With its collection of papers presented at the Kobe conference, this volume contains a thorough and comprehensive description of syringomyelia - its classification, pathology, and pathophysiology; experimental studies; and its association with abnormalities of the craniocervical junction, Chari II malformation, tethered cord, and other disorders. This compilation provides valuable state-of-the-art information for professionals in the fields of neurosurgery, neurology, and neuropathology and for all others concerned with syringomelia.

In response to persistent donor organ shortages, organs from marginal donors, such as expanded criteria donors (ECD) and donation after cardiac death (DCD) donors, are now accepted and have been successfully transplanted, reducing the waiting times for transplantation. Especially in Japan, transplantation of DCD kidneys has a relatively long history because of the difficulty or lack of national consensus in accepting brain death, which has made it possible to accumulate considerable clinical experience. Thus, the current organ shortage has stimulated interest in the use of marginal donors for transplantation. On the other hand, however, it is known that these organs have a high rate of delayed graft function and a more complicated postoperative course. These drawbacks have created the greatest clinical challenge in transplantation to date because of the current shortage and limitations of donors using ECD and DCD.

This book, prepared by distinguished authorities in their fields, is intended for clinicians and researchers. It highlights the use of marginal donors as a comparatively novel source of transplantation organs and provides a thorough overview of marginal donors from their historical origins to recent clinical applications, including the state-of-the-art science of organ/donor management, procurement, and preservation. Also provided is valuable information on ABO-incompatible donors which extend the availability of donor sources. Each chapter offers an individual analysis of the optimal requirements for the safe management and preservation of organs, including the heart, lung, liver, kidney, pancreas, and pancreatic islets.

This book identifies the key scientific articles in the field of Intensive Care and explains why these papers are important in contemporary clinical management. Identifying those influential contributors who have shaped the practice of modern Intensive care practice, the book includes commentaries on 50 seminal papers in a wide range of areas. enal This an invaluable reference for trainees, fellows, and surgeons studying for exams, as well as for seasoned surgeons and physicians who want to stay current in their field.

This book represents the first European effort to provide a collection of test descriptions used in evaluation of the compatibility of biomaterials in contact with tissues and blood. The urge to compile this book arose from the fact that it is the properties of the material which ultimatively seem to determine the functional outcome of a medical device, almost regardless of how ingenious the construction of the very device is. The longer the exposure is, the more important these basic properties become. Unfortunately only a small part of the interactive phenomena is fully elucidated and understood. This challenge reflects itself in an effort to cover numerous aspects of testing, beginning with fundamental analysis of the material, continuing with the mechanical properties, the resistance to degradation and the analysis of surface and chemical properties including adsorption patterns of proteins ending with test on cell cultures, ex vivo and in vivo. A number of the tests which are generally accepted as being important are already described as official requirements (primarily Pharmacopeas). These official requirements are not included in order to limit the size of the book. It is the aim of this book to present the tests like a recipe in a uniform way to ease the reader in finding his/her way through the material and to present it as a kind of "cook-book" in an order to provide an easy access to copy the procedures. This has unfortunately not been possible in all circumstances.

This comprehensive book discusses cartilage repair and all its aspects. These aspects vary from basic insights in cartilage biology and regeneration via MRI, to results of existing cartilage repair techniques and upcoming novel approaches. Fundamental cartilage biology is the topic covered within the first chapters of the book. These chapters not only provide an insight in healthy, damaged and regenerative cartilage but also describe developments in gene therapy and methods to enhance chondrogenesis of stemcells and prevent hypertophic differentiation. There is a huge progress in the possibilities of MR imaging of both healthy, damaged and regenerative cartilage. These developments not only enable better monitoring of cartilage repair but may also unravel the pathophysiology of the development of cartilage defects. Different cartilage repair techniques (e.g. allografts, autologous chondrocytes transplantation [ACT], microfracture), there technical aspects (e.g. developments towards an total arthroscopic approach), pitfalls, and outcomes are reported in the following chapters. In these chapters factors important for the results of cartilage repair such as meniscal repair, patient factors are described. Finally, an overview of novel cartilage repair techniques such as minced cartilage, denovo cartilage and more areas are discussed in this comprehensive addition to the literature.

This book presents the revolutionary approach to the treatment of hearing loss proposed by Professor Henryk Skarzynski and developed in collaboration with the group of internationally recognized experts on clinical and experimental otolaryngology, otosurgery, and audiology. The authors present an in-depth look at different aspects of this comprehensive concept of treatment of partial and total deafness with hearing implants, and discuss the approaches to diagnostics and patient selection, results in different groups of patients, the surgical technique, and procedures. This book also covers audiological aspects, auditory training, patient's performance, and psychology. This book is a comprehensive review of the method of partial and total deafness treatment developed and introduced into clinical practice by Professor Henryk Skarzynski. The publication is noteworthy for presenting a multifaceted approach to the subject from related science experts' and clinicians' point of view.

The increasing prevalence of morbid obesity has led the World Health Organization to coin the descriptive term "globesity" to reflect the worldwide nature of the problem. Providing health care to these patients, especially when surgery is required, can be extremely challenging owing to the specific needs in respect of logistics, facilities, and professional expertise. Appropriate care has too often been unachievable and unaffordable outside of established bariatric centers, but such centers themselves usually have insufficient capacity and resources to cope with growing demand. This book aims to provide guidance and helpful tips and tricks on how to deal with obese patients within a general surgery setting. Epidemiology, organizational and logistical aspects, nursing issues, patient assessment, anesthesiology, and surgical practicalities are expertly covered in the opening chapters. Techniques of relevance to the general surgeon are described according to anatomic region, covering the head and neck; cardiothoracic and vascular system; upper and lower GI tract; pancreas, liver and adrenal glands; urinary tract and kidneys; the reproductive system; and the abdominal wall. Results achieved by bariatric surgery worldwide are reviewed, and the book closes with a chapter devoted to plastic and reconstructive surgery. The Globesity Challenge to General Surgery highlights a need for global rethinking on public health as regards resource allocation and patterns and standards of care, improving outcomes through greater affordability.

The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. The most common cause of significant skin loss is thermal injury, followed by trauma and chronic ulcerations.

Over the past decades extraordinary advances have been made in the understanding of cellular and molecular processes of wound healing and the pathobiology of chronic wounds. This knowledge has led to wound care innovations that facilitate more rapid closure of wounds with better functional and aesthetic outcome. A sensible and resource-saving utilization of these innovative technologies requires a broad knowledge of these processes and innovations.

This book intends to give an overview about today's wound care developments in tissue engineering and skin replacement. It presents a variety of indications and diversities of clinical applications to help the surgeon select a specific procedure for each clinical situation.

Following recent developments in hypofractionated stereotactic radiation therapy (SRT) for brain and spine tumors, this new edition offers a fully updated and comprehensive "how-to" guidance on hypofractionated SRT for brain and spine metastases, glioma, benign tumors, and other tumor types. Presenting the state of the art of the technology and practice, this book: * Discusses the pros and cons of hypofractionated SRT compared to single-fraction radiosurgery, providing a deeper understanding of radiosurgery and radiobiology * Explains the toxicity and adverse effects of hypofractionated SRT including the dosage of 24 Gy in two spine SBRT fractionation schemes, aiding practitioners in communicating the risks and benefits of treatment and in obtaining consent from their patients * Outlines the current standards for safe practice, including checklists for implementation * Explores new technologies for brain and spine tumors including LITT, MR-guided focused ultrasound, and Zap technology, with chapters authored by well-recognized experts in the radiation, oncology, and neurosurgery communities; this book delivers a level of technological and clinical detail not available in journal papers This book is suitable for radiation oncologists, neurosurgeons, and medical physicists who specialize in brain and/or spine radiosurgery or want to start a program and need a comprehensive reference with key checklists for practice.

Each year approximately two million people who are burned require medical treatment. Seventy thousand require hospitalization, and nine thousand die from their injuries. "Coping StrategieS" provides the burn patient and his/her family a unique source of information and insight on the effects of disfigurement, sexuality, cosmetics, prosthetics, coping with stress, anxiety and guilt, and about employment strategies. These topics are addressed by professionals and survivors and parents of survivors--uniting all points of view and making this work important reading.

Moyamoya disease (MMD) was first reported as a new entity among vascular disorders in 1957. Named for the abnormal vascular networks found around the occluded distal internal carotid artery, it is the most common pediatric cerebrovascular disease in East Asia. In recent years large amounts of data on MMD have been collected and important investigations have been carried out in Japan and Korea, even as the pathophysiology of the disease remains to be discovered. This monograph covers a diversity of topics and presents a systematic compilation of the data and current status of MMD in clinical practice and basic research. With contributions by more than 70 authors, the book includes sections on genetics, computational analysis of hemodynamic shear stress, new imaging techniques, and endovascular treatment of MMD, along with practical applications and future directions for gene and stem cell therapies. For neurosurgeons as well as neurologists and pediatricians, this volume will help lead to more efficient and informed management of MMD.

Volume 13: Pineal, Pituitary, and Spinal Tumors is organized in six sections, for convenience and quick access to critical information. Section I, Types of Tumors includes a chapter on molecular characterization of Embryonal tumors, a chapter on diagnosis of metastatic oligodendroglioma using fine-needle aspiration cytology, one covering intra-arterial chemotherapy of oligodendroglial tumors and another on the role of cyclooxygenase-2 in the development and growth of Schwannomas, and others, closing with a chapter on trigeminal neuralgia with cerebellopontine angle tumors. Section II, Diagnosis, includes two chapters on cell counting in histopathologic slides of tumors. Section III offers three chapters which discuss aspects of intraoperative ultrasonography. Section IV covers brain tumor surgery, and Section V surveys Brain Metastasis. The final section offers a wide-ranging review of General Diseases, with chapters on, among others, Alexander Disease; Lipoma; Transplantation of human umbilical cord blood mononuclear cells in cases of neonatal hypoxic-ischemic brain damage; and a chapter discussing the use of mobile phones and brain cancer risk in children. Like its twelve predecessors in the series, this volume merits distinction for its thorough approach, its roster of 78 distinguished contributors representing 14 different countries and its detailed examination of leading-edge technology and methods.

Contemporary Coloproctology covers colorectal surgery, as practiced today, in an easily accessible format with emphasis on bringing key facts rapidly into focus. It is ideal reading both for the medical trainee and the practicing colorectal surgeon. As well as a succinct presentation of the current colorectal knowledge base, each chapter contains practical advice and pearls of wisdom from established practicing clinicians. A unique feature of the format is the identification of key references and questions and scenarios that present real life decisions in colorectal surgery. Edited and authored by outstanding surgeons in their fields, this book brings the reader expertise in surgery and management across the various conditions encountered in coloproctology.

This illustrated textbook is an essential and invaluable guide to young clinicians and researchers of Trauma and Orthopaedics, reporting all classification systems which are currently utilised in the clinical setting. It includes classifications relevant to both Elective Orthopaedic Practice and Orthopaedic Trauma. Clear graphic illustrations accompany the description of all different classification schemes in a comprehensive manner, together with a structured presentation of existing clinical evidence. In this manner each chapter of the different anatomical sites and pathologies assists the decision making of the readers regarding treatment strategy as well as informed consent of their patients. It is envisaged that this textbook will be a point of reference not only to the surgeons in training (residents) but also to senior surgeons and academic clinicians.