Management of Peri-operative Complications is examined in the issue of Surgical Clinics, guest edited Drs. Lewis Kaplan and Stanley Rosenbaum. Topics include: ? fluids and electrolytes, hypoperfusion, shock states and ACS, surgical prophylaxis and complication avoidance bundles, NSQIP, SCIP and TQIP, post-operative malnutrition and probiotic therapy, post-operative malnutrition and probiotic therapy, damage control for intra-abdominal sepsis, multi-drug resistant organisms and antibiotic management, pneumonia and acute pulmonary failure, organ failure avoidance and mitigation strategies, delirium, EtOH withdrawl and polypharmacy withdrawl states, cellular and molecular physiology of nerve injury and persistent post-operative pain, acute pain management following operation: preventing chronic post-operative pain, massive transfusion and related issues, post-op ileus, SBO and colonic dysmotility, GI hemorrhage, and in-hospital rescue therapies

The difference among pluripotent stem cells, multipotent stem cells, and unipotent stem cells is pointed out. Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: human embryonic stem cells, human mesenchymal stem cells, germ cell-derived pluripotent stem cells, induced pluripotent stem cells, human umbilical cord blood-derived stem cells, breast tumor stem cells,and hematopoietic stem cells. Because of the potential of human embryonic stem cells to produce unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential. Because of their pluripotency, these cells have been used in various applications such as tissue engineering, regenerative medicine, pharmacological and toxicological studies, and fundamental studies of cell differentiation. The formation of embryoid bodies, which are three-dimensional aggregates of embryonic stem cells, is explained as this is the first step in cell differentiation. Such embryoid body culture has been widely used as a trigger for the in vitro differentiation of embryonic stem cells. The basic capacity of self-renewal of human embryogenic stem cells is explained. The role of TGF-beta in the propagation of human embryonic stem cells is discussed. The differentiation of human embryonic stem cells into neurons, hepatocytes, cardiomyocytes, and retinal cells is fully explained. Donor policies for hematopoietic stem cells are also explained.

Cutting edge information for all oral and maxillofacial surgeons on computed tomography and guided surgery! Topics include comparison of CT and cone beam technologies, stereolithographic modeling and surgical guide concepts, virtual technologies in dentoalveolar evaluation and surgery, computer guided planning and placement of dental implants, utilization in the treatment of facial trauma, digital technologies in pathology and reconstruction, 3D technologies in craniofacial and orthognathic surgery, evaluation and fabrication of custom cosmetic facial implants, and extraoral craniofacial applications.

This issue of Surgical Oncology Clinics of North America, Guest Edited by John M. Kane III, MD, is devoted to Sarcomas.? Articles in this issue include: Prognostic Factors and Staging for Soft Tissue Sarcomas; Margin Status and Local Recurrence: Correlation or Causation?; Systemic Chemotherapy in the Adjuvant and Clinical Metastatic Setting; Pulmonary Metastasectomy; Regional Therapy for Advanced Extremity Sarcomas; Current Approaches to Retroperitoneal Sarcomas; Updates on the Management of Gastrointestinal Stromal Tumors (GIST); Soft Tissue Sarcoma: Immunologic Implications; Atypical Lipomatous Tumor/Well Differentiated Liposarcoma: What is it?; Modern Surgical Therapy: Limb Salvage and the Role of Amputation; Adjuvant Radiation Therapy: and Preoperative, Postoperative, or Not at All.

This textbook is based on the curriculum for US, UK, Canadian and Australasian Orthopedic trainees. It offers an in-depth summary of the knowledge needed to pass the boards and FRCS examination in Trauma and Orthopedic surgery. The focus is on basic information on every orthopedic subspecialty, including: surgical anatomy, basic sciences, adult reconstruction, pediatric orthopedics, foot and ankle surgery, orthopedic pathology, the spine, sports surgery, upper limb, wrist and hand surgery, and orthopedic traumas. All sections are written by experts in the respective field and utilize a consistent bullet-point format, chosen to facilitate the learning experience and help readers memorize and organize knowledge. A clear and concise "take-home message" section precedes each topic, and key references are highlighted at the end of each chapter.

The Year Book of Plastic and Aesthetic Surgery provides information valuable for the continued professional development of plastic surgeons at all levels of skill and knowledge. The Year Book of Plastic and Aesthetic Surgery presents abstracts of articles from journals worldwide that touch upon all aspects of plastic and reconstructive surgery. Commentaries from experienced surgeons evaluate the clinical importance of each article and discuss its application to clinical practice. Focused, fast, and insightful information for the busy surgeon.

There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarises this research and how it is being applied for the benefit of patients.
After an introduction to the subject, part one reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs whilst part three covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty as well as scoliosis implants. The final part of the book summarises developments in regenerative therapies such as the use of stem cells for intervertebral disc regeneration.
With its distinguished editors and international team of contributors, Biomaterials for spinal surgery is a standard reference for both those developing new biomaterials and therapies for spinal surgery and those using them in clinical practice.
Summarises recent developments in materials and therapies for the treatment of spinal conditions and examines how it is being applied for the benefit of patientsReviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgeryDiscusses the use of bone substitutes and artificial intervertebral discs and covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty

New research has shown that neuroendocrine tumors are more common than previously thought. Progress in our understanding of the molecular pathogenesis of these not-so-rare cancers has resulted in renewed interest in developinginnovative therapeutic options. In particular, novel molecular targeted agents have been shown to have significant anti-tumor activity, and integration of these therapies has led to critical advances in management.

In this volume, an outstanding group of the world s leaders in the field have assembled to convey their knowledge of the epidemiology, biology, and management of allthemajor types of neuroendocrine tumors. The book takes a multi-modality approach to understanding disease processes and therapeutics, including chapters on medical and surgical treatment as well as a chapter devoted to imaging. Throughout, the authors emphasize recent advances in our understanding of molecular biology and the subsequent emerging therapeutic options.

"Advances in Calcium Phosphate Biomaterials" presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and veteran academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications.

Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia"

Transplantation of the Heart and HeartLungs (N.E. Shumway). Physiologic Principles and Clinical Use of Hypothermia (L.K. Davis, R.F. Davis). Anesthetic Evaluation and Management in Bloodless Surgery (N.S. Faithfull). Normothermic Mycocardial Preservation, an Optimal Approach for Myocardial Protection During All Forms of OpenHeart Surgery (R.E. Engelman et al.). Pharmacologic Manipulations to Minimize Bloodloss in Cardiac Surgery (A.C. Cernaianu, A.J. DelRossi). Sutureless Intraluminal Ring Grafts for Aortic Replacement (G.M. Lemole). Immunologic Consequences of Transfusion (P.I. Tartter). Traumatic Rupture of the Thoracic Aorta (R.C. Camishion, J.B. Alexander). Cardiomyoplasty (R.C.J. Chiu). Current Status of Autotransfusion (R.A. Vertrees, A.C. Cernaianu). Transesophageal Echocardiology (W.H. O'Connor). The Use of Circulatory Support in Cardiac Surgery (R.L. Kormos). 9 additional articles. Index.

Benign esophageal diseases are common problems treated by thoracic surgeons.? This issue includes articles on the diagnosis and management of several motility and reflux disorders that are considered benign, with an emphasis on the use of cutting-edge technology.

Colorectal Cancer Screening provides a complete overview of colorectal cancer screening, from epidemiology and molecular abnormalities, to the latest screening techniques such as stool DNA and FIT, Computerized Tomography (CT) Colonography, High Definition Colonoscopes and Narrow Band Imaging. As the text is devoted entirely to CRC screening, it features many facts, principles, guidelines and figures related to screening in an easy access format. This volume provides a complete guide to colorectal cancer screening which will be informative to the subspecialist as well as the primary care practitioner. It represents the only text that provides this up to date information about a subject that is continually changing. For the primary practitioner, information on the guidelines for screening as well as increasing patient participation is presentedd. For the subspecialist, information regarding the latest imaging techniques as well as flat adenomas and chromoendoscopy are covered. The section on the molecular changes in CRC will appeal to both groups. The text includes up to date information about colorectal screening that encompasses the entire spectrum of the topic and features photographs of polyps as well as diagrams of the morphology of polyps as well as photographs of CT colonography images. Algorithms are presented for all the suggested guidelines. Chapters are devoted to patient participation in screening and risk factors as well as new imaging technology. This useful volume explains the rationale behind screening for CRC. In addition, it covers the different screening options as well as the performance characteristics, when available in the literature, for each test. This volume will be used by the sub specialists who perform screening tests as well as primary care practitioners who refer patients to be screened for colorectal cancer.

This issue of Critical Care Nursing Clinics, Guest Edited by Darlene Lovasik, RN, MN, CCRN, CNRN, will feature such article topics as: Evaluation and Work-up for Transplant; Basic Immunology; Pharmacology; Liver, Pancreas, Kidney Transplants; Living Donor Kideny, Liver Transplants; Heart, Lung, Intestinal and Multivisceral Transplants; Complications After Transplant; Patient Education; Psychosocial Concerns; Ethical Issue; Financial/Operational Considerations; Organ Donation.

Mallet Toes, Hammertoes / Claw toes - PIP correction, Hammertoes / Clawtoes - MTP correction, Flexor-to-Extensor Transfer, Metatarsalgia: Distal Metatarsal Osteotomies, Metatarsalgia: Proximal Metatarsal Osteotomies, Crossover and Valgus Toe Deformity, Revision Lesser Toe Surgery, Freiberg's Infraction, Fifth Toe Deformities, Congenital Toe Deformities, Bunionette Deformity - Etiology & Exostectomy, Bunionette deformity - Osteotomies, Postoperative Complications

A left ventricular assist device (LVAD) is a surgically implanted pump that helps the left ventricle pump blood to the rest of the body.? The purpose of this issue is to let cardiologists know about the latest devices, their complications, and the clinical situations in which they are most beneficial.

A comprehensive review of bariatric and metabolic surgery for the general surgery Topics include: The obesity epidemic/economic impact and diabetes epidemic/economic impact, physiology of obesity/diabetes, physiology of weight loss surgery, history of bariatric surgery, laparoscopic adjustable gastric banding, sleeve gastrectomy, biliopancreatic diversion/duodenal switch, laparoscopic gastric bypass, complications of laparoscopic adjustable gastric binding, complications of laparoscopic gastric bypass, outcomes/comparative effectiveness studies, co-morbidity reduction data, economic impact of bariatric surgery, adolescent bariatric surgery, revisional bariatric surgery, the future of bariatric surgery, and more

This volume of the Urologic Clinics covers the indications, controversies, and complications of Lymphadenectomy in Urologic Oncology.? Cancer of the prostate, bladder, testicles, and kidney are covered, along with new imaging modalities and complications of open and minimally invasive lymphadenectomy.

This issue of Perioperative Nursing Clinics, Guest Edited by Vivek Shetty and Grant Marshall, will focus on Collaborative Care of the Facial Injury Patient, with topics such as: Psychosocial issues; Substance Use and Injury; Intimate Partner Violence, and Barriers to Collaborative Care.

The History and Evolution of Hand Transplantation, World Experience After More Than a Decade of Clinical Hand Transplantation, How to Establish a Hand Transplant Program, Recipient Selection - Who is the Right Candidate for Hand Transplantation? Donor-related Issues in Hand Transplantation, Surgical and Technical Aspects of Hand Transplantation - Is it Just Another Replant? Functional Outcome After Hand Transplantation - What can be Achieved? Strategies to Enhance Nerve Regeneration, Immunosuppressive Protocols and Immunological Challenges Related to Hand Transplantation, Acute and Chronic Rejection in Hand Transplantation - What have we Learned? Favoring the Risk Benefit Balance for Hand Transplantation - The Pittsburgh Approach Ethical, Financial and Policy Considerations of Hand Transplantation

Management of knee trauma has changed rapidly over the past decade, with the acquisition of additional knowledge and new surgical techniques. At present, the optimal management of knee injuries requires the synthesis of multiple approaches drawn from orthopaedics and related surgical fields. The goal of this work is to comprehensively discuss the current state of the art in management of all types of knee trauma, including soft tissue and osteoarticular injuries. In order to take care of the patient with knee trauma, the orthopaedic surgeon must be able to assess and manage injuries of menisci, ligaments, articular surfaces, and bone, as all of these structures must work harmoniously for the knee to function properly. This book has been organized into five major sections. The first section on fundamental principles covers anatomy, articular cartilage injury and repair, osteochondral fractures, soft tissue management, extensile exposure, exter nal fixation, and the use of allografts in the knee. These chapters set the stage for the second section, which covers major fractures of the distal femur and tibial plateau, and the third section, where injuries of the exten sor mechanism are discussed. In section four, injuries of the menisci and ligaments are covered comprehensively, including discussion of multiple liga ment disruptions and knee dislocations. The final section covers late recon structive problems and complications of knee trauma, including knee stiff ness, malunions and nonunions, arthrodesis, total knee replacements for posttraumatic arthritis, fractures about total knee replacement, and extensor mechanism disruption in total knee replacements."

The technological capacity to transform biology - repairing, reshaping and replacing body parts, chemicals and functions - is now part of our lives. Humanity is confronted with a variety of affordable and non-invasive 'enhancement technologies': anti-ageing medicine, aesthetic surgery, cognitive and sexual enhancers, lifestyle drugs, prosthetics and hormone supplements. This collection focuses on why people find these practices so seductive and provides ethnographic insights into people's motives and aspirations as they embrace or reject enhancement technologies, which are closely entangled with negotiations over gender, class, age, nationality and ethnicity.

This issue of Neurologic Clinics addresses the cognitive impact of various forms of brain injury.

A global pool of surgeons and researchers using 3-dimensional imaging for facial plastic surgery present topics on: Image fusion in pre-operative planning; The use of 3D imaging tools including stereolithographic modeling and intraoperative navigation for maxillo-mandibular and complex orbital reconstruction; Custom-made, three-dimensional, intraoperative surgical guides for nasal reconstruction; The benefits and limits of using an integrated 3D virtual approach for maxillofacial surgery; 3D volume assessment techniques and computer-aided design and manufacturing for pre-operative fabrication of implants in head and neck reconstruction; A comparison of different new 3D imaging technologies in facial plastic surgery; 3-D photography in the objective analysis of volume augmentation including fat augmentation and dermal fillers; Assessment of different rhinoplasty techniques by overlay of before and after 3D images; 3D volumetric analysis of combined facial lifting and volumizing (volume enhancement); 3-D facial measurements and perceptions of attractiveness; Teaching 3-D sculpting to Facial Plastic Surgeons, 3-D insights on aesthetics; Creation of the virtual patient for the study of facial morphology; 3-dimensional video analysis of facial movement; 3D modeling of the behavior of facial soft tissues for understanding facial plastic surgery interventions

In this issue of Surgical Oncology Clinics of North America, Guest Editor Mark Krasna and colleagues discuss a wide range of topics devoted to lung cancer.? Articles focus on pathology; updated staging systems; epidemiology of lung cancer - smoking, second hand smoke, and genetics; molecular markers for incidence, prognosis, and response to therapy; screening; diagnostic work-up; non-invasive staging techniques; surgical resection; the role of surgery following induction therapy for stage III NSCLC; the role of adjuvant chemotherapy in NSCLC (stages I-III); and much more.