Recent years have seen important advances in the technology and techniques available to surgeons performing gynecologic surgery as well as reconstructive of clinical pelvic procedures. These developments took place in a wide variety settings from regional teaching centers to private clinical facilities. In 1996, the leading investigators from around the world gathered to discuss the present status of pelvic surgery and adhesion prevention with a look toward the future of patient care. This volume contains the proceedings of that meeting: the Third Interna tional Congress on Pelvic Surgery and Adhesion Prevention. Each chapter in cludes the material presented at the congress as well as a timely update of the authors' latest research and clinical thinking. Presentation integrating basic and clinical science provide the basis for con sidering peritoneal repair after surgery including the interaction of growth factors and other biochemical messengers. Research has increased the understanding of mesothelial reepithelialization and has led to new surgical technologies to reduce adhesion fonnation. A state-of-the-art review of emerging surgical adjuvants for adhesion prevention is provided, including discussion of barriers, gels, and poly mers as well as "designer" drugs effective at modifying the peritoneal response to injury. Assessment of clinical outcome in a wide variety of gynecologic surgical procedures brings into focus the benefits available as a result of these new tech nologies."

AsanadditiontotheEuropeanpostgraduatetrainingsystemforyoung neurosurgeons, we began to publish in 1974 this series of Advancesand Technical Standards in Neurosurgery which was later sponsored by the EuropeanAssociationofNeurosurgicalSocieties. This series was ?rst discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathersoftheseriesbeingJeanBrihaye,BernardPertuiset,FritzLoewand HugoKrayenbuhl. ThuswereestablishedtheprinciplesofEuropean- operationwhich havebeenbornfromthe Europeanspirit,?ourishedin theEuropeanAssociation,andhavebeenassociatedthroughoutwiththis series. ThefactthattheEnglishlanguageisnowtheinternationalmediumfor communicationatEuropeanscienti?cconferencesisagreatassetinterms ofmutualunderstanding. Thereforewehavedecidedtopublishallcont- butionsinEnglish,regardlessofthenativelanguageoftheauthors. All contributions are submitted to the entire editorial board before publicationofanyvolumeforscrutinyandsuggestionsforrevision. Ourseriesisnotintendedtocompetewiththepublicationsoforiginal scienti?cpapersinotherneurosurgicaljournals. Ourintentionis,rather,to present?eldsofneurosurgeryandrelatedareasinwhichimportantrecent advanceshavebeenmade. Thecontributionsarewrittenbyspecialistsin thegiven?eldsandconstitutethe?rstpartofeachvolume. Inthesecondpartofeachvolume,wepublishdetaileddescriptionsof standardoperativeproceduresandindepthreviewsofestablishedkno- edge in all aspects of neurosurgery, furnished by experienced clinicians. This part is intended primarily to assist young neurosurgeons in their postgraduatetraining. However,weareconvincedthatitwillalsobeu- fultoexperienced,fullytrainedneurosurgeons. We hope therefore that surgeons not only in Europe, but also throughouttheworld,willpro?tbythisseriesofAdvancesandTechnical StandardsinNeurosurgery. TheEditors Contents ListofContributors...XIII Advances .. Gene Technology Based Therapies in the Brain. T. Wirth1,4 and S. Yla- Herttuala1,2,3, 1A. I. Virtanen Institute,University of Kuopio, Kuopio,F- land, 2DepartmentofMedicine,UniversityofKuopioandGeneTherapyUnit, Kuopio, Finland, 3Gene Therapy Unit, Kuopio University Hospital, Kuopio, Finland,4ArkTherapeuticsOy,Kuopio,Finland Abstract...3 IntroductiontoGeneTherapy:ThePast,PresentandFuture...4 PotentialAreasforGeneTherapyintheBrain...6 GeneTherapyforParkinson'sDisease...7 GeneTherapyforAlzheimer'sDisease...8 GeneTherapyforVascularBrainDiseases...9 GeneTherapyforBrainTumours...11 ChallengesofGeneTherapyintheBrain...12 GeneTransferVectors...15 ViralGeneTransferVectors...17 Retroviruses...17 HerpesSimplexVirus-1(HSV-1)...17 Adenoviruses...18 Adeno-AssociatedVirus(AAV's)...18 Non-ViralVectors...19 Ethics...20 ConcludingRemarks...21 Acknowledgement...21 References...21 VIII Contents TechnicalStandards AnatomyoftheOrbitanditsSurgicalApproach. G. Hayek,Ph. Mercier,and H. D. Fournier, Laboratory of Anatomy, Faculty of Medicine, University of Angers,Angers,France Abstract...35 Introduction...36 AnatomyoftheOrbit...36 TheOrbitalCavity...36 TheOrbitalFasciaorPeriorbita...38 OrbitalContents...39 OrbitalMuscles...40 TheArteriesoftheOrbit...42 VeinsoftheOrbit...47 NervesoftheOrbit...48 LacrymalGland...55 ApproachRoutestotheOrbit...56 Incision...56 TheLateralApproachRoute...57 OsteoplasticTechniques...58 Non-OsteoplasticTechniques...58 TheSuperiorApproachRoute...60 TheHybridLateral/SuperiorRoute...63 Discussion...

This book represents the proceedings from a conference that took place in Dallas in the spring of 1999 which was entitled "Pediatric Gender Assignment - A Critical Reappraisal." Some participants rightfully argued that the conference really focused on the issue of pediatric gender assignment, and that reassignment was not applied in most cases. Their comments were reflected in the title of this monograph. This multidisciplinary meeting was sponsored by a conference grant from the National Institutes of Health, and a broad inquiry into this complex topic took place from many points of view. Basic scientists offered insight into mechanisms of sexual differentiation of the gonads, physical phenotype and imprinting of the central nervous system. Endocrinologists reviewed their experience in diagnosis and management, surgeons described traditional as well as innovative approaches, and there was strong representation from the ethical and behavioral sciences. In putting together such a panel, it was essential that we identify a cast of speakers who could address their viewpoints with strong convictions, and yet not let their passions render the meeting counter productive. We were not disappointed. While many differing points of view were firmly expressed by the panelists and audience, all viewpoints were accorded the respect they deserved. The concept behind the meeting and this book really originated in 1997 shortly after Diamond and Sigmundson published their long term follow up study of the John/Joan case.

Concise - designed specifically for the undergraduate medical student by a highly experienced team of surgical educators. Accessible - bullet text ideal for rapid reference, supported by key points boxes, tables and illustrations. Flexible - ideal for use when on the ward and during finals revision. Complete - print book supplemented by video clips and online question and answer material for the full learning and revision package.

Kidney Transplants are the most frequently performed solid organ transplants. Pancreas transplantation offers unique survival and quality of life benefits to selected diabetics with or without concomitant renal failure. Usually, kidney and pancreas transplant recipients are managed by the same team of physicians and surgeons. Current textbooks dealing with kidney and pancreas transplantation are unfortunately usually in the form of introductory manuals or primers and lack crucial practical detail and scientific depth relevant to the practicing physician. The transplant physicians and surgeons at Cleveland Clinic have collaborated to produce a textbook devoted to kidney and pancreas transplantation that addresses the need for a work that is well grounded in scientific principles, quantitative clinical reasoning, clinical pharmacology, tested clinical practices and overall clinical applicability. Also addressed are key aspects in the initiation, maintenance and sustained growth of viable clinical programs in kidney and pancreas transplantation.

Modern society is altering the lifestyle and longevity of its members much more quickly than evolutionary adaptation to these changes can take place. The problem of calcium deficiency in the population is compounded by the growing percentage of aged individuals with relatively fragile, less massive skeletons. Current-day civilizations are much more effective in prolonging human life in a state of relative debility than even a few decades ago. This reality is unlikely to change and mandates that we develop strategies to prevent aging-related diseases like osteoporosis before they become manifest. Osteoporosis: Genetics, Prevention and Treatment places emphasis on the (1) genetic predisposition, (2) early recognition and (3) prevention of osteoporosis. The intent is not to move the practitioner's attention away from intervention therapy of osteoporosis, but rather to expand their view of this disease as one beginning at birth and one in which susceptibility is manifest at the conclusion of adolescence, not at menopause. The book concludes with an informed view of the future in terms of the recognition, prevention and management of osteoporosis.

THE SUNDAY TIMES NUMBER ONE BESTSELLER

‘A vital book about dying. Awe-inspiring and exquisite. Obligatory reading for the living’ Nigella Lawson

At the age of thirty-six, on the verge of completing a decade’s training as a neurosurgeon, Paul Kalanithi was diagnosed with inoperable lung cancer. One day he was a doctor treating the dying, the next he was a patient struggling to live.

When Breath Becomes Air chronicles Kalanithi’s transformation from a medical student asking what makes a virtuous and meaningful life into a neurosurgeon working in the core of human identity – the brain – and finally into a patient and a new father.

What makes life worth living in the face of death? What do you do when when life is catastrophically interrupted? What does it mean to have a child as your own life fades away?

Paul Kalanithi died while working on this profoundly moving book, yet his words live on as a guide to us all. When Breath Becomes Air is a life-affirming reflection on facing our mortality and on the relationship between doctor and patient, from a gifted writer who became both.

SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2017

There are numerous textbooks detailing almost every aspect of the different laparoscopic procedures. However, in this era of evidence-based medicine, a text focusing on the controversies from the laparoscopic as well as the general surgeon's point of view is missing.

This book is not intended to be yet another textbook of laparoscopy; instead, its main purpose is to address unsettled issues of controversy. This will significantly enhance evidence-based knowledge of this developing field, stimulate thinking and discussions in rounds and meetings, assist surgeons in their decision making and stimulate further research.

This book is not aimed only at laparoscopic surgeons with their steadily increasing number but also at general surgeons and surgical trainees. It will define and sharpen points of controversy by internationally recognized authors, and thus provide 'state of the art' quality to each topic.

Many questions related to stem cell properties and neural stem cell lineage and differentiation still linger. This second edition revises and expands upon the successful first edition in order to provide the most current, cutting-edge methods of today for the scientists working to answer these questions. The use of these step-by-step, readily reproducible laboratory protocols will allow investigators to produce pure populations that can serve as a means of understanding the biology of neural stem cells and adapting them for transplantation into disease models. This is an excellent source of information and inspiration.

The possibility of treating patients with organ replacement therapy has created a new frontier in medical care. Hospitals have to deal with such vital issues as selecting potential recipients of transplants, ensuring equity in allocating organs, pre- and peri-transplantation care of patients, and post-transplantation follow-up of organ recipients. The decisions pertaining to these issues often fall to social workers, who, with their bifocal concern for individuals and society, have significant contributions to make. Here, Dhooper reviews the contributions of the few social workers in this field and suggests ways of improving their work, consolidating their professional gains, and maximizing their impact. Dhooper discusses all aspects of organ transplantation, and explores and proposes new social work roles and appropriate skills for involvement at the individual, organizational, and community levels. He deals with the larger moral, societal, economic, and technical issues, as well as the here-and-now concerns of the social worker. Recommended for social workers trained for practice in the 1990s and beyond, and particularly those specializing in health and mental health social work.

This volume of proceedings contains in their entirety the reports submitted at the 6th International Congress of Minimally Invasive Surgery and the 3rd World Congress of the Academy for Multidisciplinary Neurotraumatology, held concurrently in Nagoya, Japan, in March 2005, and provides valuable insights into the latest innovations in clinical neurosurgery for practitioners from a broad range of disciplines.

This book is an up-to-date reference on all aspects of anticoagulation and hemostasis in neurosurgery. After an opening section on basic principles and drug classes in current use, detailed consideration is given to coagulation issues relevant to all patients, not just neurosurgical ones. The coverage includes, for example, deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. A variety of important issues specific to neurosurgical practice are then addressed, and a summary of current guidelines and best practices is provided. By bringing together the latest knowledge from across the discipline, this book will serve as a sound basis for informed decision making in surgical practice. It will be of daily value for neurosurgeons and trainees worldwide and will also be of interest to emergency room physicians, surgeons in general, critical care physicians, neurologists, and hospital medicine specialists.

As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series of Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Neurosurgical Societies. This series was first discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the series being Jean Brihaye, Bernard Pertuiset, Fritz Loew and Hugo Krayenbiihl. Thus were established the principles of European co operation which have been born from the European spirit, flourished in the European Association, and have throughout been associated with this series. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publi cation of any volume. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the first part of each volume.

TRENDS IN LINGUISTICS is a series of books that open new perspectives in our understanding of language. The series publishes state-of-the-art work on core areas of linguistics across theoretical frameworks, as well as studies that provide new insights by approaching language from an interdisciplinary perspective. TRENDS IN LINGUISTICS considers itself a forum for cutting-edge research based on solid empirical data on language in its various manifestations, including sign languages. It regards linguistic variation in its synchronic and diachronic dimensions as well as in its social contexts as important sources of insight for a better understanding of the design of linguistic systems and the ecology and evolution of language. TRENDS IN LINGUISTICS publishes monographs and outstanding dissertations as well as edited volumes, which provide the opportunity to address controversial topics from different empirical and theoretical viewpoints. High quality standards are ensured through anonymous reviewing.

1 Anatomische Grundlagen.- 1.1 Zahnentwicklung.- 1.2 Zahngewebe.- 1.2.1 Dentin.- 1.2.2 Schmelz.- 1.2.3 Wurzelzement.- 1.2.4 Zahnpulpa.- 1.2.5 Parodontium.- 2 Anomalien der Zahne.- 2.1 Stoerungen der Schmelzbildung.- 2.2 Stoerungen der Dentinbildung.- 2.3 Farbanomalien der Zahne.- 3 Karies.- 3.1 Schmelzkaries.- 3.1.1 Fissurenkaries.- 3.1.2 Approximalkaries.- 3.2 Dentinkaries.- 3.2.1 Dentinkaries vor Schmelzkavitat.- 3.2.2 Dentinkaries nach Schmelzkavitat.- 3.2.3 Zonen der Dentinkaries.- 3.3 Chronische Karies.- 3.4 Zementkaries.- 3.5 Strahlenkaries.- 4 Veranderungen der Pulpa.- 4.1 Regressive Veranderungen der Pulpa.- 4.2 Traumatische Veranderungen der Pulpa.- 4.3 Entzundungen der Pulpa (Pulpitis).- 4.3.1 Akute Pulpitis.- 4.3.2 Chronische Pulpitis.- 4.3.2.1 Formen der chronischen Pulpitis.- 4.3.2.2 Wurzelfullung.- 5 Parodontopathien.- 5.1 Gingivitis.- 5.1.1 Akute Gingivitis.- 5.1.1.1 Akute nekrotisierende, ulzeroese Gingivitis (Plaut-Vincent-Gingivitis).- 5.1.2 Gingivaabszess.- 5.2 Chronische Gingivitis.- 5.2.1 Chronische fibrosierende Gingivitis durch Medikamente.- 5.2.1.1 Phenytoin.- 5.2.1.2 Ciclosporin.- 5.2.1.3 Nifedipin.- 5.2.2 Hormonal beeinflusste chronische Gingivitis.- 5.3 Epulis.- 5.3.1 Epulis granulomatosa.- 5.3.2 Epulis fibromatosa (oder fibrosa, fibrase Hyperplasie).- 5.3.3 Riesenzellepulis, peripheres Riesenzellgranulom (Epulis gigantocellularis).- 5.4 Parodontitis.- 5.4.1 Apikale Parodontitis.- 5.4.1.1 Akute apikale Parodontitis.- 5.4.1.2 Periapikaler Abszess.- 5.4.1.3 Chronische apikale Parodontitis.- 6 Odontogene Zysten.- 6.1 Definition und Einteilung.- 6.2 Allgemeine Gesichtspunkte der Zystenentwicklung.- 6.3 Klinik der Zysten.- 6.4 Klassifikation.- 6.5 Entzundlich bedingte Zysten.- 6.5.1 Radikulare Zysten.- 6.5.2 Residualzysten.- 6.6 Dysontogenetische Zysten.- 6.6.1 Primordialzysten (Keratozysten).- 6.6.2 Follikulare Zysten.- 6.6.3 Durchbruchszysten (Eruptionszysten).- 6.6.4 Gingivale Zysten.- 6.6.5 Kalzifizierende odontogene Zysten.- 6.6.6 Paradentale Zysten.- 6.6.7 Glandulare odontogene Zysten.- 6.6.8 Zysten im Rahmen von Fehlbildungssyndromen.- 6.7 Nicht odontogene Kieferzysten.- 7 Odontogene Tumoren.- 7.1 Gutartige odontogene Tumoren.- 7.1.1 Ameloblastom.- 7.1.2 Odontogener plattenepithelialer Tumor.- 7.1.3 Kalzifizierender epithelialer odontogener Tumor (Pindborg-Tumor).- 7.1.4 Odontogener Klarzelltumor.- 7.1.5 Ameloblastisches Fibrom.- 7.1.6 Ameloblastisches Fibrodentinom (Dentinom und amelo-blastisches Fibroodontom).- 7.1.7 Odontoameloblastom.- 7.1.8 Adenomatoider odontogener Tumor.- 7.1.9 Kalzifizierende odontogene Zyste.- 7.1.10 Komplexes Odontom.- 7.1.11 Zusammengesetztes Odontom (Compound odontoma).- 7.1.12 Odontogenes Fibrom (Fibrom des Kiefers).- 7.1.13 Myxom (odontogenes Myxom, Myxofibrom).- 7.1.14 Gutartiges Zementoblastom (Zementoblastom, echtes Zementom).- 7.1.14.1 Echtes Zementom.- 7.1.14.2 Zemento-ossifizierendes Fibrom.- 7.2 Boesartige odontogene Tumoren.- 7.2.1 Odontogene Karzinome.- 7.2.1.1 Boesartiges Ameloblastom.- 7.2.1.2 Primares intraossares Karzinom.- 7.2.1.3 Boesartige Varianten anderer odontogener epithelialer Tumoren.- 7.2.1.4 Boesartige Tumoren in odontogenen Zysten.- 7.2.2 Odontogenes Sarkom.- 7.2.2.1 Ameloblastisches Fibrosarkom (Ameloblastisches Sarkom).- 7.2.2.2 Ameloblastisches Fibrodentinosarkom (Ameloblastisches Fibroodontosarkom).- 7.2.2.3 Odontogenes Karzinosarkom.- 8 Erkrankungen des Kieferknochens.- 8.1 Osteomyelitis.- 8.1.1 Akute, eitrige Osteomyelitis.- 8.1.2 Chronische, eitrige Osteomyelitis.- 8.1.3 Chronische, fokal-sklerosierende Osteomyelitis.- 8.1.4 Chronische, diffus-sklerosierende Osteomyelitis.- 8.1.5 Chronische Osteomyelitis mit proliferativer Periostitis.- 8.1.6 Sonderformen der Osteomyelitis.- 8.1.6.1 Mykobakterielle Osteomyelitis.- 8.1.6.2 Aktinomykotische Osteomyelitis.- 8.1.6.3 Bruchspaltosteomyelitis.- 8.1.6.4 Radioosteomyelitis.- 8.2 Osteosklerose.- 8.3 Osteomalazie.- 8.4 Hypoparathyreoidismus.- 8.5 Primarer Hyperparathyreoidismus.-

Cell-Cycle Mechanisms and Neuronal Cell Death examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degeneration. Leading Authors discuss this topic in relation to the major neurological disorders, including Alzheimer 's disease, stroke and epilepsy. This book serves to gain new insights into the molecular determinants of neuronal death and to establish new targets for therapeutic intervention.

A comprehensive description of macroscopic, microscopic, and radiological methods for the diagnosis of bone diseases. The book presents all the procedures involved in diagnosis, using not only radiological and histological techniques, but also modern immunohistochemical and scintigraphic methods. Succinct and well-structured therapeutic recommendations are provided for an array of bone diseases, making this a practice-oriented reference work for pathologists, radiologists, rheumatologists, and orthopedists.

Re-EngineeringoftheDamagedBrainandSpinalCord isdedicatedtoTetsuoKanno,M. D. ProfessorofNeurosurgery Bypresenting theoriginal papers thatmakeupthis thefeaturesofthelocalmedicallandscapeinthe- third supplement we wish to make a further contri- gionswheretheyareenacted. Whatismore,progr- bution to the issue of functional rehabilitation, this sivenew?ndingsmustbealsosubjectedtoafrequent soimportantandfascinatingmodernareaofresearch revision. Ontopofthis,itshouldnotbeforgottenthat inthe?eldofneurosciences. Thecongresspaperswe even when committal therapy guidelines are c- haveselectedconstituteagoodre?ectionofthetrans- sistentlyapplied,thereareconsiderablevariationsin disciplinary objectives. The literature references are therangeofpotentialcomplicationsandintheo- designedasaguidetoleadtheinterestedreadertoa comeofprospectivecontrolledmulti-centreandmul- deeperandmoredetailedunderstandingoftheindi- nationalstudiesontheissueofqualitymanagement. vidualissues. Functionalrehabilitationhasbeenanoriginaltask The demand for "evidence-based medicine" is well ofneurosurgeryfromtheveryoutset. The1990shave justi?ed; however, it rapidly comes up against the enteredtheannalsofbrainresearchasthe"Decadeof limitsoffeasibility,especiallywherecontrolledthe- theBrain". Sincethentherehasbeenaneverstronger peuticstudiesareconcerned. TheCochrancollection growthofneuroscienti?cinterestworldwide,accom- of high-quality evidence-based healthcare databases paniedbysubstantial?nancialengagement. Thishas hasthusfarbeenofnohelptousindrawingupthe- primarily resulted in advances in basic neuro- peutic recommendations for the re-engineering of biologicalandneurophysiologicalresearchandalsoin brain and spinal-cord lesions. Today as ever, the thegrowthofneuroscienti?cknowledgeaboutbasic opinion of experts and empirically based medical mechanismsformotor control,paincontrol,aware- treatment and posttraumatic neurorehabilitation ness, cognition, learning and memory. The conse- continuetooccupyanindispensablepositionforthe quencemustbetoensurethattheadvancesmadeinthe everydayclinicalpracticeofneurosurgicalandneu- neuroscienti?cresearchareaareadequatelyexpanded traumatological therapies. Promising adjunct - intopracticalneurosurgicalcareandre-engineeringof proachesincludeneuropharmacology,forcascadesof brainandspinalcordlesionsandtoensureuponnew molecular interactions are known to be underlying approaches. Following this a fundamental path will activity-dependent plasticity and skills learning, as resultinanimprovedandmoree%ocientpreventionin many of these processes involve the major tra- thefuture,themeasuresthatstandrightatthefore- mitters. Furthermore,biologicalinterventionsby- front of all rehabilitation principles, meaning that ingendogenousneuronsandgliaaswellasexogenous conventionalconceptsmustbemodi?edtokeeppace stemcells,bone-marrowcells,macrophages,andother withthemoretask-speci?c,intensive,andprogressive types may promote the regeneration of nerve cells, demands. In this connection a series of guidelines, tissue, and neural circuitry. Class one studies have recommendations, and expert opinions and also beenmade,andnowclasstwostudieshavebeeni- algorithms have been elaborated by national and tiated, for example in connection with acute spinal international expert panels and multidisciplinary as- cord injury (SCI). The clinical application of fu- sociationsfortheacutemedicalcareofpatients.

Transferring hematopoietic stem cells and immune cells has continued to be a promising therapeutic alternative and a fascinating area of cell biology as well as a field of persistent procedural problems. This explains why substantial parts of basic research on cell growth and differentiation, immune tolerance and antitumor effects, gene transfer, minimal residual disease and supportive care have settled around clinical transplantation in hematology and oncology. This second volume updates the current role of allogeneic and autologous transplantation in leukemias, lymphomas and solid cancers, including controversial strategies and novel experimental approaches. Outstanding representatives of leading groups guarantee first-hand information and indicate how we can work and cooperate more effectively to the benefit of our patients.

Reoperation is one of surgery's greatest challenges. This book provides a practical reference on how to prevent, identify and treat all abdominal complications. Organised primarily by body system Reoperative Abdominal Surgery covers the spectrum of conditions and complications faced by the general surgeon. Separate chapters also cover safety issues, and specific issues related to diagnosis, surgical technique and patient presentation. Combining the expertise and advice of leading international surgeons the book offers a clinical instructive manual for trainee and practising surgeons. Focus on abdominal surgery the key province of the general surgeon Expert guidance on the prevention, identification and management of post-operative complications Key reference on difficult surgical area for residents and young surgeons Experience and advice from best surgeons around the world Covers entire spectrum of reoperative abdominal surgery

This manual reviews the definitions and typical approach to quality assurance in healthcare and includes a review of the most prominent quality studies. A program for quality management in surgery is presented with chapters reviewing patient safety and external reporting requirements. An introduction to medical malpractice and risk management is also provided and followed by a chapter on how to implement the necessary behavioral changes to improve quality practices. The appendix includes useful protocols, forms and order sets.

Eureka: General Surgery and Urology is an innovative book for medical students that fully integrates core science, clinical medicine and surgery. The book benefits from an engaging and authoritative text, written by specialists in the field, and has several key features to help you really understand the subject: Chapter starter questions - to get you thinking about the topic before you start reading Break out boxes which contain essential key knowledge Clinical cases to help you understand the material in a clinical context Unique graphic narratives which are especially useful for visual learners End of chapter answers to the starter questions A final self-assessment chapter of Single Best Answers to really help test and reinforce your knowledge The book starts with the First Principles chapter which clearly explains key concepts such as assessment of the patient fitness for surgery, patient consent and pain management. The Clinical Essentials chapter provides an overview of the symptoms and signs of surgical disease, investigations and management options. A series of disease-based chapters briefly describe, by system, relevant structure and function, history and examination and main surgical presentations, each chapter introduced by engaging clinical cases that feature unique graphic narratives. The Emergencies chapter covers the principles of immediate care in situations such as acute appendicitis. Finally, the Self-Assessment chapter comprises 80 multiple choice questions in clinical Single Best Answer format, to thoroughly test your understanding of the subject. The Eureka series of books are designed to be a 'one stop shop': they contain all the key information you need to know to succeed in your studies and pass your exams.

Key Clinical Topics in Critical Care offers an indispensable and practical guide for exam revision and clinical practice. Written and edited by specialists with a wealth of clinical experience, this book provides rapid access to core topics in critical care. Each topic is written in a concise and easy-to-digest format, making this book the essential resource for exam revision and quick reference at the point of care. * Over 100 topics presented in alpha order, from acute coronary syndrome to weaning from ventilation * Succinct coverage of clinical features, diagnosis, treatment and complications * Effective exam revision for FRCA, FFICM and EDIC candidates * Includes clinical photos and diagrams to improve understanding of key concepts * Contributions from experienced specialists to ensure authoritative, accurate content