The use of human tissue for transplantation is becoming a billion-dollar business. This book is the first comprehensive exploration of the American tissue transplantation industry. It traces the chain of distribution of musculoskeletal tissue (e.g. bones and ligaments) and skin from the generous donation of grieving families to its transplantation into hundreds of thousands of persons each year. Commodification, commercialization, and the occasional use of tissue for "cosmetic" surgery have raised ethical questions about the acceptability of "markets" in human body parts that have been altruistically donated by families. Inevitably, questions about the informed consent and the need for responsible stewardship by the industry have been raised, often in the Press.

The book provides a comprehensive background to these ethical problems by explaining the historical development, breadth, and organization of the tissue industry, including the technical developments that have made it simultaneously clinically relevant and an attractive market for investment capital. It explores the similarities and differences in how government regulates other tissues and solid organs (such as hearts and kidneys). Contributions to the book come from an interdisciplinary group of scholars, industry representatives, government regulators, and, not least, families who have donated tissue from their dead loved ones.

This issue of the Atlas of the Oral and Maxillofacial Surgery Clinics of North America focuses on Fat Grafting for Aesthetic Facial Surgery, and is edited by Drs. Shahrokh C. Bagheri, Husain Ali Khan, and Behnam Bohluli. Articles will include: Current techniques in fat grafting; Fat grafting in different facial aesthetic units; Fat grafts with stem cells; Fat grafts with growth factors; Fat grafts for facial augmentation; Fat grafts as an adjunct to other facial aesthetic surgeries; Fat grafts in maxillofacial reconstruction; Fat grafts in orthognathic surgery; Fat grafts for periorbital rejuvenation; Complications of fat grafting; Fat grafting: Challenges and debates; The past, present, and future of facial fat grafting; and more!

This issue of Surgical Clinics of North America focuses on Trauma, and is edited by Drs. Oscar Guillamondegui and Bradley Dennis. Articles will include: Prehospital Assessment of Trauma; Trauma Systems; Assessment and Resuscitation in Trauma Management; Balanced Resuscitation in Trauma Management; Surgical Management of Traumatic Brain Injury; Surgical Management of Spinal Cord Injury; Surgical Management of Chest Injury; Surgical Management of Abdominal Trauma: Solid Organ Injury; Surgical Management of Abdominal Trauma: Hollow Viscus Injury; Surgical Management of Musculoskeletal Trauma; Surgical Management of Vascular Trauma; Surgical Management of Geriatric Trauma; Radiology of Trauma and the General Surgeon; Trauma Education and Prevention, and more!

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Elin R. Sigurdson, is devoted to Clinical Trials in Surgical Oncology. Dr. Sigurdson has assembled expert authors to review the following topics: Commentary on Randomized Controlled Trials; Randomized Clinical Trials in Soft Tissue Sarcoma; Randomized Clinical Trials in Gastrointestinal Stromal Tumors; Randomized Clinical Trials in Melanoma; Randomized Clinical Trials in Breast Cancer; Randomized Clinical Trials in Gastroesophageal Carcinoma; Randomized Clinical Trials in Hepatocellular Carcinoma; An Update on Randomized Clinical Trials in Advanced and Metastatic Colorectal Carcinoma; Randomized Clinical Trials in Colon and Rectal Cancer; Randomized Clinical Trials in Anal Cancers; The Elderly in Randomized Clinical Trials; Hereditary Syndromes in Clinical Trials; Future Clinical Trials: Genetically Driven Trials; Randomized Clinical Trials in Neuroendocrine Tumors, and more!

This issue of Oral and Maxillofacial Surgery Clinics of North America focuses on Evaluation of the Surgical Margin, and is edited by Drs. Joshua E. Lubek and Kelly Magliocca. Articles will include: Understanding the Surgical Margin: A Pathologist's Perspective; Understanding the Surgical Margin: A Molecular Assessment; Margin Analysis: Squamous Cell Carcinoma of the Oral Cavity; Margin Analysis: Squamous Cell Carcinoma of the Oropharynx; Bone Margin Analysis: Segmental Versus Marginal Resection in Malignant Disease; Bone Margin Analysis for Benign Odontogenic Tumors; Bone Margin Analysis for Osteonecrosis and Osteomyelitis of the Jaws; Margin Analysis: Malignant Salivary Gland Neoplasms of the Head and Neck; Margin Analysis: Benign Salivary Gland Neoplasms of the Head and Neck; Margin Analysis: Cutaneous Malignancy of the Head and Neck; Margin Analysis: Sarcoma of the Head and Neck; Has Reconstruction Improved Tumor Surgery Outcomes?; and more!

This issue of Interventional Cardiology Clinics, edited by the series Editor-in-Chief, Dr. Matthew Price, will cover Transcatheter Closure of Patent Foramen Ovale. Some of the topics discussed in this issue include, but are not limited to, PFO and the Interatrial Septum: Clinical-Anatomic Correlations; Current Dataset for PFO Closure in Cryptogenic; Stroke: Randomized Clinical Trials and Observational Studies; PFO closure: Devices and Technique; Identification and quantification of PFO-mediated shunts: echocardiography and transcranial Doppler; PFO closure for Hypoxemia; and Imaging Assessment of the interatrial Septum for ASD and PFO closure, among others.

FRCS General Surgery Section 1: 500 SBAs and EMIs, Second Edition has been thoroughly revised to ensure the content remains completely up to date and accurate. With 50 new questions, FRCS General Surgery Section 1: 500 SBAs and EMIs offers the most relevant and comprehensive set of practice questions for trainees preparing for the exam. Chapters are mapped to the syllabus to deliver structured revision in all the key topics tested in the exam. Featuring a wealth of practice questions and fully descriptive answers, this book provides the essential revision tool to maximise chances of success. 500 SBA and EMI scenario based questions reflecting the formats encountered in the exam Answers feature concise, case-based descriptions to consolidate knowledge Extensive evidence-based referencing to relate theory to clinical practice Visually-enhanced answers to improve understanding of key concepts

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Kelly Hunt, is devoted to Breast Cancer. Dr. Hunt has assembled expert authors to review the following topics: Tomosynthesis in breast cancer imaging: how does it fit into preoperative evaluation and surveillance?; Lobular breast cancer: different disease, different algorithms?; Hypofractionated radiation therapy in breast conserving therapy; Oncoplastic breast reconstruction: should all patients be considered?; Neoadjuvant endocrine therapy: who benefits most?; Breast cancer disparities: how can we leverage genomics to improve outcomes?; Anatomy and breast cancer staging: is it still relevant?; When does atypical ductal hyperplasia require surgical intervention?; Surgical intervention for lymphedema; Are there alternative strategies in the local management of DCIS?; Genetic testing and genetic counseling: what is standard of care?; Molecular subtypes and local-regional control of breast cancer; Intraoperative margin assessment in breast cancer management; Triple negative breast cancer: who should receive neoadjuvant chemotherapy?; and more!

Advanced Perioperative Crisis Management is a high-yield, clinically-relevant resource for understanding the epidemiology, pathophysiology, assessment, and management of a wide variety of perioperative emergencies. Three introductory chapters review a critical thinking approach to the unstable or pulseless patient, crisis resource management principles to improve team performance and the importance of cognitive aids in adhering to guidelines during perioperative crises. The remaining sections cover six major areas of patient instability: cardiac, pulmonary, neurologic, metabolic/endocrine, and toxin-related disorders, and shock states, as well as specific emergencies for obstetrical and pediatric patients. Each chapter opens with a clinical case, followed by a discussion of the relevant evidence. Case-based learning discussion questions, which can be used for self-assessment or in the classroom, round out each chapter. Advanced Perioperative Crisis Management is an ideal resource for trainees, clinicians, and nurses who work in the perioperative arena, from the operating room to the postoperative surgical ward.

This issue of Surgical Clinics of North America focuses on Surgical Critical Care, and is edited by Dr. Cynthia Talley. Articles will include: Brain Death; Indications and Methods of Anticoagulant Reversal; Ultrasound and Other Innovations for the ICU; Severe Sepsis Strategies; Renal Failure in the Critically Ill; Decompensated Cirrhosis and Fluid Resuscitation; Gastrointestinal Complications; Nutrition for the Critically Ill; End of Life and Goals of Care; Resuscitation for Hypovolemic Shock; Ventilator Strategies for COPD and ARDS; Traumatic Brain Injury Management; The Mobility and Impact of Frailty in the ICU; Delirium and PTSD Prevention; and more!

The purpose of this book is to contribute to basic and clinical medical research on cochlear implants for inner ear malformation and cochlear nerve deficiency. Cochlear implantation for children is performed worldwide, and the outcomes concerning speech and hearing acquisition are epoch-making. However, there are some difficulties associated with applying this operative treatment to patients who have complicated inner ear malformations or cochlear nerve deficiencies that have slowed the development of their speech, hearing, and/or sense of balance. The first part of the book outlines the fundamental aspects of inner ear maldevelopment to facilitate readers' understanding of cochlear implantation from the point of view of embryology, morphology, and genetics. In turn, the second part describes current clinical cases and presents successful clinical reports. The book offers a primary resource for otolaryngologists, neurologists, and pediatricians with an interest in this field.

1 Die Press-Fit-Verankerung.- 2 Indikation, Technik und Ergebnisse der konischen Schraubpfanne bei Primar-und Revisionseingriffen.- 3 Keramik-Polyethylen versus Metall-Polyethylen - Eine in vivo-Analyse.- 4 Keramische Pfanneneinsatze fur totalen Huftgelenkersatz.- 5 Mittelfristige Ergebnisse mit der Keramik-Gleitpaarung in der Huftendoprothetik.- 6 Werkstoffkundliche Aspekte zum UHMW-Polyethylen.- 7 Muller-Bogenschaft-Prothese - Langzeitergebnisse mit vollstandiger Datenerfassung..- 8 Verankerungsprinzipien des Exeter-Schaftes.- 9 Der Lubinus-Schaft.- 10 CLS-Multicenterstudie - 11jahrige Erfahrungen.- 11 Konische Schaftverankerung bei zementfreien Huftendoprothesen.- 12 Die CHENDO-Femurprothese - Trabekular orientiertes Endoprothesensystem.- 13 Bionik als Grundlage eines trabekular orientierten Endoprothesensystems.- 14 CL. ESKA-Stiele/Endoprothesen.- 15 Die Druckscheibenprothese - Fruhergebnisse bei Patienten mit Arthritis.- 16 Zementfreie Schaftverankerung der Individualprothese..- 17 Axis-Stufenschaft.- 18 Die ESKA-Schenkelendoprothese Cut zur inneren metaphysaren Fixation.- 19 Resultate nach zementfreier Implantation des BiContact-Huftendoprothesengeradschaftes.- 20 Robotik am Huftgelenk - Das Robotersystem Robodoc.- 21 Computerassistierter Einbau von Huftprothesenschaften mit dem CASPAR-System.- 22 Erste Erfahrungen mit dem Surgigate-System von Medivision bei der Implantation der Huftpfanne.- 23 Erste Erfahrungen aus der klinischen Testung der computerassistierten Pfannenpositionierung bei der Implantation von Huft-Total-Endoprothesen mit dem NavitrackTM-System.- 24 Computergestutzte Prothesenauswahl und Implantationskontrolle.

This volume provides a concise yet comprehensive overview on surgical procedures performed on the cirrhotic patient. The text explains the underlying pathophysiologic alterations in liver disease and cirrhosis, provides assessment of disease severity and risk factors, and helps to predict potential outcomes based on the nature of the operation. Operations discussed in detail include bariatric surgery, colorectal surgery, hepatic surgery, kidney transplantation, gynecological procedures, neurosurgical procedures, and ophthalmic surgery. The book is also supplemented with instructive color illustrations and tables. Written by experts in the field, Surgical Procedures on the Cirrhotic Patient is a valuable, multidisciplinary resource for clinicians who treat the cirrhotic patient. With a Foreword by Thomas E. Starzl, the father of liver transplantation.

Guest editors Jin Bo Tang and Grey Giddons have assembled an expert team of authors on the topic of Hand Surgery in Asia and Europe. Article topics include: Multiple Digit and major limb replantation in Asia and Europe; Microsurgical flaps in repair and reconstruction of the hand; Composite tissue transfer: Novel techniques; Primary flexor tendon repair with early active motion: Part 1. Experience in Asia; Primary flexor tendon repair with early active motion: Part 2. Experience in Europe; Conservative treatment of hand fractures in United Kingdom; Current European practice in proximal interphalangeal joint arthroplasty; Treatment of scaphoid fractures: European approaches; Carpal ligaments: A functional classification; Current European practice in wrist arthroplasty and more!

This issue of Facial Plastic Surgery Clinics, guest edited by Dr. Benjamin C. Marcus, is devoted to Functional Rhinoplasty. Articles in this outstanding issue include: Essential Anatomy and Evaluation for Functional Rhinoplasty; Septoplasty: Basic and Advanced Techniques; The Role of the Inferior Turbinate in Rhinoplasty; The External Nasal Valve; The Internal Valve: Dynamic and Static Repairs; The Art of Osteotomies; Repair of Nasal Septum Perforations; Management of Pediatric Rhinoplasty; Cleft Septorhinoplasty: Form and Function; The Saddle Deformity: Camouflage and Reconstruction; Revision Functional Surgery: Salvaging Function; and Advances in Technology for Functional Rhinoplasty.

This issue of Surgical Clinics of North America focuses on Cardiothoracic Surgery, and is edited by Dr. John H. Braxton. Articles will include: Review of ICU Management of the Cardiac and Thoracic Surgery Patient and the Team Approach; Minimally Invasive and Robotically Assisted Cardiac Surgery; Surgical Treatment of Heart Failure; The Changing Face of the Cardiothoracic Surgical Team; Thoracic Trauma and Management; Minimally Invasive and Robotically Assisted Thoracic Surgery; The Impact on Less Invasive Surgery on Esophageal Diseases; Lung Cancer Screening and its Impact of Surgical Volume; The Surgical Treatment of Coronary Artery Occlusive Disease: Modern Treatment Strategies for an Age Old Problem; Transcutaneous Valve Repair and Update; Robotic Lobectomy and Segmentectomy: Technical Details and Results; Diagnostic Imaging and Newer Modalities for Thoracic Diseases: PET Imaging and EBUS for Staging and its Implication for Lung Cancer; Mitral Valve Repair: French Correction vs. American Correction; Cardiac Screening in the Noncardiac Surgery Patient; and more!

Each year, Advances in Surgery reviews the most current practices in general surgery. A distinguished editorial board, headed by Dr. John Cameron, identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in general surgery bring concepts to a clinical level and explore their everyday impact on patient care.

This issue of Facial Plastic Surgery CLinics, guest edited by Dr. James B. Lucas, is devoted to Facial Reconstruction Post-Mohs Surgery. Articles in this issue include Anatomy of the Skin and the Pathogenesis of Non-Melanoma Skin Cancer; Mohs Micrographic Surgery: the Essentials; Physiology and Biomechanics of Skin Flaps; Flap Basics I: Rotation and Transposition Flaps; Flap Basics II: Advancement Flaps; Flap Basics III: Interpolated Flaps; Skin and Composite Grafting Techniques; Scalp and Forehead Defects; Defects of the Eyelids; Auricular Defects; Cutaneous Nasal Defects; Defects of the Lips and Chin; Cheek Defects; and Scar Revision and Recontouring Post-Mohs Surgery.