Even the brightest lights grow dim if they are not attended, and the great old torch-bearers and their works needs refreshment. After Nicaise all the Europeans, except the English speaking people, had new editions and translations of Guy's Major Surgery. With this translation of Nicaise's edition, all of the eight seminal treatises by the surgeons who brought surgery anew into Europe now are available to the English-Reader. The long discursive Introductions and footnotes by Nicaise and Joubert, and footnotes and explanatory insertions by this translator supplement Guy's text with a fine history of French surgery. Indeed, as Nicaise wrote in the historical Introduction to his edition of Pierre Franco, if we were to combine the introductions in his editions of Henri de Mondeville, Pierre Franco, and Guy de Chauliac with Malgaigne's Introduction to his edition of Ambroise Pare, we will have a complete history of European Surgery before the modern era. Guy's era was that of the Great Plague, and his book was written after its first invasion. His respectful attitude toward his colleagues and his suave gentility secured him as an officer of the Church, and as a Surgeon for The Popes at Avignon.

1. Imaging for Orthopedics (Including Normal X-rays) 2. Infection of Bone and Joints 3. Tuberculosis of Bone and Joints 4. Orthopedics Oncology 5. Fracture and Fracture Healing 6. Advanced Trauma Life Support 7. Upper Limb Traumatology 8. Spinal Injury 9. Pelvis and Hip Injury 10. Lower Limb Traumatology 11. Fracture Management 12. Amputations 13. Sports Injury 14. Neuromuscular Disease 15. Peripheral Nerve Injury 16. Joint Disorders 17. Metabolic Disorders of Bone 18. Pediatric Orthopedics 19. Osteochondritis and Avascular Necrosis 20. DNB CET Questions 21. Complete Summary of Orthopedics (Including Recent MCQs)

This book describes the molecular mechanisms of lung cancer development and progression that determine therapeutic interventions in the era of genomics, when the rapid evolution in lung cancer diagnosis and treatment necessitates critical review of new results to integrate advances into practice. The text opens with background and emerging information regarding the molecular biology of lung cancer pathogenesis. Updated results regarding lung cancer prevention and screening are discussed, followed by chapters on diagnostic techniques and pathological evaluation. This leads on to a detailed presentation of treatment modalities, from surgery and radiation therapy to standard chemotherapy and targeted agents. The coverage includes resistance to therapy and the emergence of immunotherapy for lung cancer; in addition, the current evidence in respect of small cell lung cancer is summarized. The book presents insights from experts across disciplines to emphasize the importance of collaborative care. Advances in our understanding of issues in geriatric oncology and palliative care complete the comprehensive discussion of lung cancer.

This book is intended for surgeons wanting to take their antireflux practice to an advanced level. It focuses on what experts do in real life, highlights pitfalls in skillful patient selection and fundoplication surgical technique, and addresses how to handle the "curve balls". It also provides recommendations on obtaining high patient satisfaction and building relationships with referring physicians. It is intended as an "expert" level manual to help readers move to the next level in their practices. From patient assessment and selection, anticipation of perioperative challenges, intraoperative problem-solving and technique, and postoperative management of side-effects, to reducing long-term recurrence rates and resumption of antisecretory medication, these expert authors dig deep to share the pearls of wisdom that make the difference between the average surgeon and the expert. Written by experts in the field, Fundoplication Surgery: A Clinical Guide to OptimizingResults confronts the issues that have hindered the broader use of fundoplication nationally and is a valuable resource and reference guide for addressing ambiguous symptoms and test results in one's practice.

This new edition presents information and knowledge on the field of biomedical devices and surgical tools. The authors look at the interactions between nanotechnology, nanomaterials, design, modeling, and tools for surgical and dental applications, as well as how nanostructured surfaces can be created for the purposes of improving cell adhesion between medical devices and the human body. Each original chapter is revised in this second edition and describes developments in coatings for heart valves, stents, hip and knee joints, cardiovascular devices, orthodontic applications, and regenerative materials such as bone substitutes. There are also 8 new chapters that address: Microvascular anastomoses Inhaler devices used for pulmonary delivery of medical aerosols Surface modification of interference screws Biomechanics of the mandible (a detailed case study) Safety and medical devices The synthesis of nanostructured material Delivery of anticancer molecules using carbon nanotubes Nano and micro coatings for medical devices This book is appropriate for engineers, material scientists, chemists, physicists, biologists, medical and dental professionals with an interest in biomedical devices and tools, and researchers in the same fields.

This book presents regenerative strategies for the treatment of knee joint disabilities. The book is composed of four main sections totaling 19 chapters which review the current knowledge on the clinical management and preclinical regenerative strategies. It examines the role of different natural-based biomaterials as scaffolds and implants for addressing different tissue lesions in the knee joint. Section one provides an updated and comprehensive discussion on articular cartilage tissue regeneration. Section two focuses on the important contributions for bone and osteochondral tissue engineering. Section three overview the recent advances on meniscus repair/regeneration strategies. Finally, section four further discusses the current strategies for treatment of ligament lesions. Each chapter is prepared by world know expert on their fields, so we do firmly believe that the proposed book will be a reference in the area of biomaterials for regenerative medicine.

One: Historical Reflections.- 1. Reflections on the development of organ transplantation.- Two: Immunology of Organ Transplantation.- 2. Cellular and molecular mechanisms of allograft rejection.- 3. What does the alloreactive T cell see?.- 4. HLA matching and organ transplantation.- 5. An effective strategy for transplantation of highly sensitized patients.- 6. Rapid lymphocyte crossmatching for renal transplantation.- Three: Organ Allograft Rejection.- 7. Fifteen-year experience with fine needle aspiration biopsies at the University of Helsinki.- 8. Study of antibody specificity in highly sensitized patients using human monoclonal antibody technology.- 9. Idiotypic-Antiidiotypic antibody interaction and renal transplant survival.- Four: Immunosuppression.- 10. Transplantation and blood transfusion in 1990.- 11. Quadruple-drug immunosuppressive induction treatments for immunological high-risk patients in cadaveric renal transplantation using poly-and monoclonal antibodies.- 12. Sequential combination immunotherapy for cadaveric renal transplantation: OKT3 versus rabbit ATG induction.- 13. Multi-organ transplant experience with OKT3 and strategies for use at the University of Cincinnati Medical Center.- 14. Cyclosporine withdrawal in renal transplant recipients maintained on azathioprine, prednisone and cyclosporine.- 15. Early experience with FK 506 in liver transplantation.- 16. Deoxyspergualin. A novel immunosuppressant: experimental and clinical studies.- 17. Preliminary results with FK 506 in pancreas grafting in a nonhuman primate model.- 18. The effect of DST on graft outcome - the Turkish experience.- 19. Induction of specific unresponsiveness (tolerance) to experimental and clinical allografts using polyclonal antilymphocyte serum and donor-specific bone marrow.- 20. Comparison of cyclosporine assays using radioimmunoassay, fluorescent polarization immunoassay and high-performance liquid chromatography.- Five: Renal Transplantation.- 21. Long-term outcome in renal transplantation.- 22. Ten-year experience with 500 renal transplants.- 23. Long-term results in recipients of cadaveric renal allografts under cyclosporine therapy.- 24. Transplantation of single and double kidneys from pediatric donors.- 25. ABO-incompatible living related donor transplantation.- 26. The use of single pediatric cadaver kidneys for transplantation into adult recipients.- 27. Living unrelated donor renal transplantation.- 28. Renal transplantation in Tunisia - a three-year experience.- 29. Renal transplantation in children.- 30. Kidney donors - long-term follow up.- 31. Current techniques for permanent vascular access surgery - experience with 930 procedures.- 32. Results of 319 consecutive renal transplants from living related and living unrelated donors in Iran.- Six: Liver Transplantation.- 33. Liver transplantation: current status.- 34. An overview of liver transplantation therapy for children.- 35. Current anesthetic management in clinical liver transplantation.- 36. Risk factors in adult liver transplant recipients.- 37. The concept of reduced-size liver transplantation, including split-liver and living related liver transplantation.- 38. Immunological factors contributing to outcome in liver transplantation.- 39. Transplantation for hepatobiliary malignancies.- 40. The diagnosis and management of massive blood loss during liver transplantation.- 41. Early clinical experience with cluster resection and transplantation for right upper quadrant abdominal malignancy.- Seven: Heart/Heart-Lung Transplants.- 42. Lung transplantation: current techniques and outcomes.- 43. Heart-lung transplantation at the University of Minnesota.- 44. Specificity and sensitivity of the cytoimmunological monitoring (CIM): differentiation between cardiac rejection, viral, bacterial, or fungal infection.- Eight: Pancreas Transplantation.- 45. International Pancreas Transplantation Registry report.- 46. Techniques and experience of pancreatic transplantation wit...

The title of this book is self-explanatory, so if you are reading this, chances are you or someone you love is considering a surgical procedure in the near future. No one would argue that a surgery, any surgery, could be a fearful and traumatic event. This is why the Pre Surgical Care book and program were developed and written---to give anyone a completely supportive and totally personal care program for all levels of body, mind, and spirit. You will learn things like: Minerals that will accelerate the entire healing process. How to find the best surgeon for you, not just the best surgeon-that's not enough-- but the best surgeon for YOU. Vitamins that will boost your immunological system and increase tissue regeneration. Flower remedies that will help control and eliminate the worry, fear, and anxiety surrounding surgery. Foods to eat exactly one week before surgery that will keep inflammation to a minimum. How to speak to your surgeon so he will give you his very best personal care and surgical skill. This is an important point-not to be assumed or taken for granted. Herbs that will give you maximum protection against possible infection. Homeopathic medicine that will dramatically improve and speed your recovery and rejuvenation time. Flower essences that will help enhance an optimistic and dynamic, positive attitude. Simple mental techniques to activate your minds incredible healing powers. This information is of vital importance. Whether this event is a few months away or a few days, it will be of great benefit. . Pre Surgical Care is clearly written, easy to understand, and simple to follow. Pre Surgical Care is a comprehensive and effective program to help you or anyone, even ayoung child, prepare for surgery-any surgery.

This book offers a theoretical and practical overview of the specific ethical and legal issues in pediatric organ transplantation. Written by a team of leading experts, Ethical Issues in Pediatric Organ Transplantation addresses those difficult ethical questions concerning clinical, organizational, legal and policy issues including donor, recipient and allocation issues. Challenging topics, including children as donors, donation after cardiac death, misattributed paternity, familial conflicts of interest, developmental disability as a listing criteria, small bowel transplant, and considerations in navigating the media are discussed. It serves as a fundamental handbook and resource for pediatricians, transplant health care professionals, trainees, graduate students, scholars, practitioners of bioethics and health policy makers.

This book discusses geometric and mathematical models that can be used to study fluid and structural mechanics in the cardiovascular system. Where traditional research methodologies in the human cardiovascular system are challenging due to its invasive nature, several recent advances in medical imaging and computational fluid and solid mechanics modelling now provide new and exciting research opportunities. This emerging field of study is multi-disciplinary, involving numerical methods, computational science, fluid and structural mechanics, and biomedical engineering. Certainly any new student or researcher in this field may feel overwhelmed by the wide range of disciplines that need to be understood. This unique book is one of the first to bring together knowledge from multiple disciplines, providing a starting point to each of the individual disciplines involved, attempting to ease the steep learning curve. This book presents elementary knowledge on the physiology of the cardiovascular system; basic knowledge and techniques on reconstructing geometric models from medical imaging; mathematics that describe fluid and structural mechanics, and corresponding numerical/computational methods to solve its equations and problems. Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. The reader is then exposed to some of the latest research activities through a summary of breakthrough research models, findings, and techniques. The book's approach is aimed at students and researchers entering this field from engineering, applied mathematics, biotechnology or medicine, wishing to engage in this emerging and exciting field of computational hemodynamics modelling.

Breast Disease: Comprehensive Management provides a clear, concise source of information in order to make real-life, evidence-based decisions for all aspects of breast disease, both benign and malignant. The volume provides the latest breakthroughs in breast cancer research, ranging from paradigm shifts in the surgical management of the axilla, the changing role of adjuvant and neoadjuvant chemotherapy, the impact of molecular medicine in decision-making and the controversial role of prophylactic mastectomy in our era. Within select chapters, "How I do it" clinical scenarios are supplied and described in very practical terms. Also included at the end of each chapter are synoptic questions with detailed answers, akin to the self-assessment (SESAP) format questions and answers. These questions provide a basis for continuous medical education (CME) for the practicing physician and surgeon, further in surgical oncology and breast surgery, medical oncologists, radiation oncologists, and breast radiologists enhancing a focused approach to the management of breast disease in preparation for the American Board of Surgery certification and re-certification for the general surgeon. Breast Disease: Comprehensive Management is of great value to general surgeons, breast surgeons, surgical oncologists, general surgery residents, and fellows.

Vascular surgery and endovascular surgery are both modalities to treat vascular disease. Endovascular describes a minimally invasive approach commonly done through needle puncture and a sheath. Traditional vascular surgery is more invasive and involves incisions, which is more surgical in nature. This book provides vascular surgeons and trainees with the latest advances and techniques in vascular and endovascular surgery. Divided into seventeen sections the book covers procedures for numerous vascular disorders including venous insufficiency, lower limb arterial disease, mycotic aneurysms, pelvic venous reflux, renovascular hypertension, and many more. The comprehensive text is further enhanced by clinical photographs, diagrams and tables to assist learning. The previous edition (9789352705986) published in 2018.

This volume provides a comprehensive, state-of-the art review of inflammatory bowel disease and its management through the use of telemedicine applications. The book reviews barriers to successful outcomes in patients with IBD and offers a rationale for how self-management and telemedicine approaches can improve care in chronic illnesses such as IBD. This volume also includes a summary of the burden of telephone encounters in patients with IBD, characteristics of frequent callers to the office, outcomes associated with high telephone use, and strategies to provide education via telephone to patients with IBD. Prior literature on implementation of teleconsultation in research and clinical practice, as well as mobile applications used to track symptoms, quality of life, diet, and medication use in IBD are also explored in the book. Written by experts in the field, Telemanagement of Inflammatory Bowel Disease is a valuable resource for gastroenterologists, surgeons, a nd other clinicians dealing with, and interested in, this novel adjunct to routine care for inflammatory bowel disease.

This book covers the latest advances, applications, and challenges in orthopedic biomaterials. Topics covered include materials for orthopedic applications, including nanomaterials, biomimetic materials, calcium phosphates, polymers, biodegradable metals, bone grafts/implants, and biomaterial-mediated drug delivery. Absorbable orthopedic biomaterials and challenges related to orthopedic biomaterials are covered in detail. This is an ideal book for graduate and undergraduate students, researchers, and professionals working with orthopedic biomaterials and tissue engineering. This book also: Describes biodegradable metals for orthopedic applications, such as Zn-based medical implants Thoroughly covers various materials for orthopedic applications, including absorbable orthopedic biomaterials with a focus on polymers Details the state-of-the-art research on orthopedic nanomaterials and nanotechnology

Since the mid 1990s, transplantation knowledge and techniques, as well as insights into pharmacology, have improved, thus enabling greater access to transplantation for patients. The pool of organs for transplantation is stable, and therefore insufficient to cope with the growing demand. To adjust demand and resources in the most equitable way, organ procurement and allocation have been organized nationally and often across borders. The national and international organ exchange programmes were studied and discussed during the Congress on Organ Allocation, from which this book is derived. This book describes the state of the art in the management of waiting lists and the allocation of organs in transplantation. It includes chapters on the possibilities of expanding the pool of available cadaver organs. It also analyzes the results of transplantation of cadaver organs from older donors and marginal, non-heart-beating donors. Transplantation policies based on the offering of organs by living donors are also described, as is the impact of delayed graft function on organ allocation.

Therapeutic Laparoscopy for Digestive Disease is intended to give the practicing surgeon or trainee an in-depth analysis of the technical aspects of the most commonly performed laparoscopic procedures, their indications, contraindications, and complications. Included are strategies to prevent complications as well as ways to handle them once they occur. Heavily illustrated, the book breaks new ground in visualizing operative procedures and problems. Seven sections, comprising the core curriculum of accepted procedures in laparoscopic surgery, present gallbladder disease, common bile duct exploration, hernia, colon diseases, anti-reflux procedures, acute abdomen and the role of diagnostic laparoscopy, and emerging procedures on the spleen and adrenals. Recognized leaders in the field tackle each section, emphasizing what to do when and how to solve acute situations. The book also features a patient information component for each section, providing the necessary background on the procedure, post-operative period, and recovery. These pages are perforated for inclusion in a binder in the patient office as well as for photocopying as patient take-home instructions. Therapeutic Laparoscopy for Digestive Disease is a practical, must-have resource for the general surgeon, imparting the clinical insight needed for successful performance of the core miminally invasive procedures as well as a source of useful patient information for the office practice.