Neurosurgical procedures are becoming more common and are taking place in the operating room and in interventional suites. Procedures that used to be performed only at major academic institutions are also being done in small community hospitals, and anesthesiologists in private practice are being asked to care for these patients. In many cases, treatment options are controversial or rapidly evolving. Close cooperation between the anesthesiologist and neurosurgeon is essential to achieve optimal outcomes and early recognition of any adverse events so appropriate therapy can be implemented. Fundamentals of Neuroanesthesia is a comprehensive guide to neuroanesthesia that discusses neurophysiology, neuroanatomy, and neurosurgical procedures and offers practical approaches and solutions to administering neuroanesthesia and providing perioperative care for neurosurgical patients. Chapters emphasize clinical management of neurosurgical problems that may be encountered in community practice as well as major academic medical centers. Highlighted key points, figures, algorithms, and management procedures supplement the text. This book is a must-have volume for general anesthesiologists, anesthesiology fellows, and subspecialists.

In this issue of Neurosurgery Clinics, Guest Editor James A. Stadler brings his considerable expertise to the topic of syndromic neurosurgery. Top experts in the field cover key topics such as Syndromic epilepsy, tumor syndromes, syndromic craniosynostosis, and more. Provides in-depth, clinical reviews on syndromic neurosurgery, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 14 relevant, practice-oriented topics including The history of syndromic neurosurgery; Multidisciplinary evaluation of neurosurgical patients with genetic syndromes; Neurosurgical evaluation and management of children with achondroplasia; Neurosurgical evaluation and management of patients with connective tissue disorders; and more.

In this issue of Surgical Clinics, Guest Editor Brett H. Waibel brings his considerable expertise to the topic of surgical clinical care. Top experts in the field cover key topics such as Topical coagulant agents, Antibiotic therapy in the ICU, Telemedicine and the intensive care unit, and more. Provides in-depth, clinical reviews on surgical critical care, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 14 relevant, practice-oriented topics, such as ARDS/management of pulmonary illness in era of COVID; Ultrasound and other advance hemodynamic monitoring modalities in the intensive care unit; Systemic anticoagulation and reversal, including Direct Oral Anticoagulants; Management of decompensated cirrhosis and associated syndromes; and more.

In this issue of Surgical Oncology Clinics, guest editor Oluwadamilola "Lola" Fayanju brings considerable expertise to the topic of Disparities and Determinants of Health in Surgical Oncology. Provides in-depth, clinical reviews on the latest updates on Disparities and Determinants of Health in Surgical Oncology, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue of Facial Plastic Surgery Clinics, guest editors J. David Kriet and Clinton D. Humphrey bring their considerable expertise to the topic of Modern Approaches to Facial and Athletic Injuries. Top experts in the field cover key topics such as nasal fractures, orbital fractures, zygomaticomaxillary fractures, mandibular body injuries, and more. Contains 12 relevant, practice-oriented topics including Soft Tissue Injuries Including Auricular Hematoma Management; Concussion in the Athlete and Return to Play Guidelines; General Overview of Facial Trauma Patient Evaluation; and more. Provides in-depth clinical reviews on modern approaches to facial and athletic injuries, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Oral and Maxillofacial Surgery Clinics, guest editor Harry Dym brings his considerable expertise to the topic of Clinical Pharmacology for the Oral and Maxillofacial Surgeon. Top experts in the field cover key topics such as a review of sedation agents, acute pain management, and more. Contains 17 relevant, practice-oriented topics including Emergency Drugs for the Oral and Maxillofacial Surgeon Office; Update on Medications for Oral Sedation in the Oral and Maxillofacial Surgery Office; Pharmacologic Treatment for Tempromandibular and TMJ Disorders; and more. Provides in-depth clinical reviews on Clinical Pharmacology for the Oral and Maxillofacial Surgeon, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

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In this issue of Thoracic Surgery Clinics, Guest Editor Farid Shamji brings considerable expertise to the topic of Lung Cancer in this second issue covering this topic. Top experts in the field cover key topics such as biological treatments, improving anesthesia safety in pulmonary resection for lung cancer, history of surgical instruments in thoracic surgery, The Hemithorax - the empty chest syndrome, and more. Provides in-depth, clinical reviews on lung cancer, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 16 relevant, practice-oriented topics including Assessment of Operability and Resectability in Lung Cancer; Complications of chest wall resection in conjunction with pulmonary resection; Sepsis in the postpneumonectomy space: pathogenesis, recognition and management; Neuroendocrine cancers of the lung: natural history, pathological classification, biological behaviour and treatment; and more.

Vascular Surgery: A Clinical Guide to Decision-making is a concise but comprehensive resource for operating vascular surgeons and clinicians. It serves as an essential reference manual, particularly to young vascular surgeons, for consulting the basic scientific knowledge of pathogenesis of various illnesses, as well as how to approach them in a clinical setting. Adopting a translational approach, this book dissects the background of vascular pathology and links it to application in surgical techniques, as well as providing practical tips and tricks for surgical maneuvers. With insights and suggestions from various experienced and skilled vascular surgeons, this book covers a range of topics including the origin of diseases, clinical presentation, and therapeutic options, from medical therapy to surgical or endovascular approach. Each chapter also reviews international cutting-edge research in the vascular field and its clinical application, illuminating future developments in the field. With the contributions of first-class vascular surgeons, this book also covers uncommon and advanced case studies while exploring the pros and cons of each intervention option, helping practitioners make informed decisions when facing difficult cases. This unique reference also helps young surgeons to make quick decisions in challenging cases, such as how to choose between open and endo treatment.

This book addresses instruments, methodologies and diagnostic methods used to evaluate and diagnose human movement, locomotion and physical status in general. Starting from historical perspective, the idea of understanding human locomotion by applying technical measurement devices and incorporating measurement data into physical representation of gross body movement is presented and explained, an approach known as inverse dynamics. With this approach as a kind of umbrella concept, components of measurement systems including relevant signal and data processing methods are described. Modern instruments to capture body movement by measuring its kinematics, kinetics and surface electromyography (sEMG) are thus described; all systems being used dominantly-if not exclusively-in a movement analysis laboratory setting. Focusing mainly on human posture and gait, but including also examples of movement patterns from selected kinesiological and sports activities, the book attempts to present essentials of biomechanics and biomedical engineering approach to this subject matter. It illustrates how data collected and elaborated by modern engineering technology can complement traditional expert knowledge of a kinesiologist or a medical doctor. The book is applicable in the fields of sports, physical activities, as well as in medical diagnostics and rehabilitation. The examples of this book's practical application might be in evaluation of efficiency of human gait, in evaluation of skeletal muscle fatigue in physical exercise, in biomechanical diagnostics of traumatological conditions requiring orthopaedic treatment and the like. This book can also be used in planning and executing research endeavours, particularly in a clinical context as a reference for various diagnostics procedures. It presents the lecture notes of a course carrying the same name within Medical Studies in English at the University of Zagreb for more than a decade.

"Medical Care of the Liver Transplant Patient" looks at monitoring and maintaining the health of organ recipients and donors, pre, during and post-operatively.

There are twenty-nine chapters containing practical advice on total patient management. They are arranged into 8 sections and follow the stages of transplantation from first indication and selection of potential recipient, through to acute recovery, long-term follow-up and continued health.

In this edition there are new chapters on special considerations in liver transplant patients such as viral hepatitis, alcoholic liver disease and live donor liver transplantation. It also contains the very latest information concerning complications and recurring problems after transplantation. Another new chapter considers fresh approaches and developments in the future.

This is a vital reference to all members of the medical team involved at different stages in the care of liver transplantation patients including hepatologists, gastroenterologists, transplant surgeons, specialist nurses, and nutritionists.

This issue of Facial Plastic Surgery Clinics, Guest Edited by Dr. Yong Ju Jang, is dedicated to Facial Plastic Surgery Procedures in the Non-Caucasian Population. This issue is one of four selected each year by our series consulting editor, Dr. J. Regan Thomas. Articles in this issue include, but are not limited to: Facelift for East Asian, Facelift for African descendants, Forehead lift for Asian, Lower eyelid and midface rejuvenation, Blepharoplasty for Asian (Incisional technique), Non incisional blepharoplasty for Asian, Cosmetic bone contouring surgery for Asian, Two jaw surgery for Asian, Special considerations in facial reconstruction in the Non-Caucasian Patient, Rhinoplasty for African descendants, Cosmetic augmentation rhinoplasty for East Asians, and Special consideration in rhinoplasty for east Asian deformed noses. Provides in-depth, clinical reviews on the latest updates in Facial Plastic Surgery Procedures in the Non-Caucasian Population, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

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This issue of Neurosurgery Clinics, guest edited by Dr. Domagoj Coric, provides an Update on Motion Preservation Technologies. This issue is one of four selected each year by our series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. This issue discusses state-of-the-art indications, technique, devices, complications and evidence basis for motion preserving technologies in the cervical and lumbar spines. Topics covered in this issue will include: Cervical Total Disc Replacement: Indications and Technique, Cervical Total Disc Replacement: Off-label and Expanded Indications, Cervical Total Disc Replacement: FDA-approved Devices, Cervical Total Disc Replacement: Novel Devices, Cervical Spine Surgery: Arthroplasty versus Fusion versus Posterior Foraminotomy, Cervical Total Disc Replacement: Complications and Complication Avoidance, Cervical Total Disc Replacement: Long-term Outcomes, Biomechanics of Cervical Arthroplasty Devices, Adjacent-level Disease following Spinal Arthroplasty, Lumbar Total Disc Replacement: Current Usage, and Posterior Lumbar Facet Replacement and Arthroplasty. Provides in-depth, clinical reviews on the latest updates in Motion Preservation Technologies, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This issue of Clinics in Plastic Surgery, Guest Edited by Drs. Brian R. Gastman and Michael W. Neumeister, is dedicated to Melanoma. This issue is one of four selected each year. Articles in this issue include, but are not limited to: Melanoma risk factors and prevention, Biology and signaling pathways of melanoma, Immunobiology of melanoma, Clinical diagnosis and classification, Histopathologic and molecular diagnosis of melanoma, AJCC staging and other platforms to assess prognosis and risk, Current treatment guidelines of primary melanoma including wide excision and use of sentinel node biopsy, Dermatologic follow-up and assessment of suspicious lesions, Immunotherapy of melanoma, Targeted therapies for melanoma, Non-operative intra-tumoral therapies, Role of radiation for locoregional and distant metastatic melanoma, Adjuvant and neoadjuvant therapy for melanoma, Surgery of the nodal basins for trunk and extremity melanoma, Extirpative considerations of melanoma of the head and neck, Treatment of lentigo melanoma of the head and neck, Reconstructive considerations of melanoma of the head and neck, Melanoma of the hands and feet, Rare variants of melanoma, and Emerging therapies for melanoma.

Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside, Third Edition comprehensively investigates key discoveries in the field of bone biology. New aspects of bone cancer biology are treated in new chapters covering exosomes, autophagy, and metabolism. These have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Third Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with 40% new material. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases. This revision opens the door to myeloma with two short chapters dedicated to this bone-associated disease.

The heart is our most important - and perhaps most mysterious - organ.

Every day it pumps 9000 litres of blood and beats around 100,000 times. But the heart is more than just a pump. In all major human cultures, it is seen as the source of love, sympathy, joy, courage, strength and wisdom. Why is this so?

Having witnessed the extraordinary complexity and unpredictability of human hearts in the operating theatre - each one individual in its make-up, like a fingerprint - heart surgeon Reinhard Friedl went on a search for answers. He examined closely the latest findings in neurocardiology and psychocardiology, and in The Beat of Life he shares his discoveries, using riveting personal stories to illustrate the complex relationship between the heart, the brain and the psyche.