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Hepatitis C Virus and Liver Transplantation is designed to provide a comprehensive and state-of-the-art overview of the major issues specific to the field of liver transplantation and hepatitis C virus infection. The sections of the book have been structured to review the overall scope of issues of recurrent hepatitis C in different complex settings, including retransplantation, HIV-coinfected patients or in the setting of suboptimal graft donors. This book provides up-to-date information on the application of new therapies to the field of liver transplantation. It provides the most recent data on their efficacy, the management of side effects, as well as the potential interactions and specific problems associated with their use in the transplant setting. Finally, an appraisal of the risks and benefits of using organs from anti-HCV positive donors is presented. This book provides concise and actual materials for several important topics that are simply not adequately covered by current available literature. Hepatitis C Virus and Liver Transplantation will provide a unique and valuable resource in the field of liver transplantation and will be of great value to Hepatologists, Transplant and Abdominal Surgeons, Oncologists, as well as Fellows and Residents training in these fields.
The symposium from which this book originates represents a sig nificant watershed in the field of intraoperative neural monitoring, since the participants concluded that electrophysiologic monitoring techniques should be considered a "standard of care" for surgical pro cedures that place the central nervous system (CNS) at risk for injury. Specifically, it was agreed that the somatosensory-evoked potential (SEP) is a remarkably reliable and sensitive indicator of several aspects of CNS function, and should be routinely employed as an intraopera tive monitor during many neurosurgical and orthopedic procedures. The significance of this conclusion cannot be overstated, for at the time of this writing, intraoperative monitoring methods based on evoked-potential analyses are still considered experimental and are not in routine use. The reasons for this are not clear, given the accu mulation of literature and expertise on this subject over the past five years. Granted, the cost of electrophysiological monitoring equip ment is high, but only initially. The benefits of injury prevention far outweigh these costs, from both medical and economic viewpoints. It is our sincere hope and goal that the medical community be made aware of the value of intraoperative neural monitoring."
Physical Therapy – Treatment of Common Orthopedic Conditions is a highly illustrated, evidence-based guide to the treatment of a range of common orthopaedic disorders, edited by US based experts in the field. Divided into sixteen chapters, across three sections, the book begins with a section on upper extremity, including conditions such as thoracic outlet syndrome, rotator cuff impingement, and carpal tunnel syndrome. The second section covers the spine, including sprains and strains, and cervical radiculopathy. The final section focuses on lower extremity, covering conditions such as hamstring strain, tendinopathy, and medial tibial stress syndrome. Each chapter begins with an overview of important information for diagnosis, followed by detailed evaluation and treatment approaches, which include conservative therapy, as well as complimentary, alternative, medical and surgical interventions. The text is enhanced by 850 full colour images and illustrations. Physical Therapy – Treatment of Common Orthopedic Conditions references more than 1700 journal articles and books, ensuring authoritative content throughout this valuable resource for physiotherapists. Key Points Evidence-based guide to the treatment of a range of common orthopaedic conditions USA-based, expert editorial team References from over 1700 authoritative journal articles and books 850 full colour images and illustrations
Preface. Part One: Pathophysiology of ischemia and reperfusion. 1. Moderate ischemic injury and myocardial stunning; M.E. Zughaib, P.B. McCay, M.O. Jeroudi, C. Hartley, Jian-Zhong Sun, S. Seikili, Xiao-Ying Li, R. Bolli. 2. Severe ischemic injury and the oxygen paradox; H.M. Piper, B. Siegmund, K.-D. Schluter. 3. Role of leukocytes in reperfusion injury; S.L. Hale, R.A. Kloner. 4. Ischemia of the neonatal heart; F.M. Lupinetti. Part Two: Concepts of cardioplegia. 5. Cardioplegia with an intracellular formulation; C.J. Preusse. 6. Cardioplegia with an extracellular formulation; D.J. Chambers, M.V. Braimbridge. 7. Blood cardioplegic strategies during adult cardiac operations; G.D. Buckberg, B.S. Allen, F. Beyersdorf. Part Three: Clinical application of cardioplegia. 8. High volume perfusion; I.B. Krukenkamp, C.A. Caldarone, P. Burns, S. Levitsky. 9. Intermittent coronary perfusion; H.D. Schulte. 10. Retrograde perfusion; P. Menasche. 11. Cardiac arrest by ventricular fibrillation; C.W. Akins. 12. Myocardial preservation in the immature heart; J.E. Mayer, Jr. Part Four: Evaluation of cardioplegic methodology. 13. High-energy phosphates and their catabolites; J.W. de Jong, T. Huizer, M. Janssen, R. Krams, M. Tavenier, P.D. Verdouw. 14. Lactate monitoring during and after cardiopulmonary bypass: an approach implicating a perioperative measure for cardiac energy metabolism; E.-G. Krause, D. Pfeiffer, U. Wollenberger, H.-G. Wollert. 15. Myocardialtissue pH in the assessment of the extent of myocardial ischemia and the adequacy of myocardial protection; M.B. Tantillo, S.F. Khuri. 16. Morphology of the acute and chronic ischemic myocardium in man; M. Borgers, W. Flameng. 17. Muscle birefringence; S. Darracott-Cankovic. 18. How to measure cardiac energy expenditure; M.Takaki, T. Namba, J. Araki, K. Ishioka, H. Ito, T. Akashi, Ling Yun Zhao, Dan Dan Zhao, Miao Liu, W. Fujii, M. Takaki, H. Suga. 19. Cardioplegia and cardiac function; D. Baumgart, R. Schulz, T. Ehring, G. Heusch. Index.
This thesis lays the groundwork for the automatic supervision of the laser incision process, which aims to complement surgeons' perception of the state of tissues and enhance their control over laser incisions. The research problem is formulated as the estimation of variables that are representative of the state of tissues during laser cutting. Prior research in this area leveraged numerical computation methods that bear a high computational cost and are not straightforward to use in a surgical setting. This book proposes a novel solution to this problem, using models inspired by the ability of experienced surgeons to perform precise and clean laser cutting. It shows that these new models, which were extracted from experimental data using statistical learning techniques, are straightforward to use in a surgical setup, allowing greater precision in laser-based surgical procedures.
This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
Anesthesia and the Central Nervous System is a textbook for a postgraduate course as well as a reference for all anesthesiologists which presents many of the latest concepts in anesthesiology within a brief formal presentation. An outstanding faculty presents topics relating to the biochemistry, physiology, and pharmacology of the nervous system, the anesthetic management of intracranial and spinal cord surgery, and the intensive care management of central nervous system disease. Each chapter is a brief but sharply focused glimpse of the interests in anesthesia. This textbook is the eleventh in a continuing series documenting the proceedings of the Postgraduate Course in Salt Lake City.
Written byinternationally acclaimedspecialists, "Upper Abdominal Surgery"provides pertinent and concise procedure descriptionsspanning benign and malignant problems and minimally invasive procedures. Complications are reviewed when appropriate for the organ system and problem, creating a book that is both comprehensive and accessible. Stages of operative approaches with relevant technical considerations are outlined in an easily understandable manner. The text is illustrated with photographs that depict anatomic or technical principles. Forming part of the series, "Surgery: Complications, Risks and Consequences," this volume "Upper Abdominal Surgery"provides a valuable resource for all general surgeons and residents in training. Other healthcare providers will also find this a useful resource. "
William P. Cooney III, R. A. Berger, and K. N. An Orthopedic Biomechanics Laboratory Department of Orthopedic Surgery Mayo Clinic and Mayo Foundation Rochester, MN 55905, U. S. A. As surgeons struggle to find new insights into the complex diseases and deformities that involve the wrist and hand, new insights are being provided by applied anatomy, physiology and biomechanics to these important areas. Indeed, a fresh new interaction of disciplines has immersed in which anatomists, bioengineers and surgeons examine together basic functions and principles that can provide a strong foundation for future growth. Clinical interest in the hand and wrist are now at a peak on an international level. Economic implications of disability affecting the hand and wrist are recognized that have international scope crossing oceans, cultures, languages and political philosophies. As with any struggle, a common ground for understanding is essential. NATO conferences such as this symposium on Biomechanics of the Hand and Wrist provides such a basis upon which to build discernment of fundamental postulates. As a start, basic research directed at studies of anatomy, pathology and pathophysiology and mechanical modeling is essential. To take these important steps further forward, funding from government and industry are needed to consider fundamental principles within the material sciences, biomechanical disciplines, applied anatomy and physiology and concepts of engineering modeling that have been applied to other areas of the musculoskeletal system.
This book examines British and American women's narratives of cosmetic surgery collected between 1995 and 2007, with particular attention to what those narratives say about the contemporary status of cosmetic surgery and 'local' ideas about its legitimate and illegitimate uses. The book argues that British and American women employ justificatory strategies that normalize aesthetic procedures by aligning them with nationally-specific notions of 'appropriate' medical treatment. Consumers' narratives are also informed by 'global' discourses that portray cosmetic surgery as a lifestyle choice and a tool for holding one's own in the competitive marketplace of employment or heterosexual romance. Such meanings are in turn reworked by women in their own accounting, at the same time that accounts are limited by culturally-available symbolic resources and institutional structures. Where the general and specific are incompatible - as is more often the case in the British context - women respond by stressing the power of externally-imposed appearance mandates and their entitlement to self-care.
Injury of the spinal cord has been known since antiquity. There is no cure for the injury and until modern times patients died rapidly from a combination of pressure sores and urinary tract infection. Treatment consists of preventing complications until the spine has stabilised and the patient can be rehabilitated to an independent life. "History of the Treatment of Spinal Injuries" explores how this treatment developed in the Ancient World, the Middle Ages, in Europe, Great Britain and latterly in the United States. It describes how these principles of treatment were recognised and explores the relationship and rivalry of the powerful personalities of the doctors who developed this treatment against the social background at different times.
Laparoscopic Colorectal Surgery, Second Edition is fully revised and updated and reflects an authoritative, team-oriented approach to the latest state-of-the-art laparoscopic colorectal procedures and surgical techniques. Written by pioneers in the field, this text will supply surgeons with all the information necessary to accomplish advanced laparoscopic procedures. Comprehensive discussions of positioning, instrumentation, cannulas, surgical techniques, special considerations, and considerations in cancer surgery are featured for a wide variety of major operative procedures. This new Second Edition includes updated information on laparoscopic colorectal procedures, including hand-assisted laparoscopic procedures and new chapters on the physiology of pneumoperitoneum, laparoscopic anatomy of the colon and rectum, and evidence-based discussion of outcomes. The text is complemented by over 200 line drawings created exclusively for the textbook.
Written entirely by surgical urologists, Surgical Management of Urolithiasis: Percutaneous, Shockwave and Ureteroscopy presents a comprehensive overview of the past, present, and future of surgical techniques, with a focus on educating urologists on the full spectrum of stone procedures. In addition to the technical issues, detailed complications are described. Basic as well as advanced techniques are presented in both a didactic and visual mode with representative endoscopic images and radiographs. Recent advancements which are not routinely a core component of surgical training programs are also covered in detail. Compact and extensively illustrated, Surgical Management of Urolithiasis: Percutaneous, Shockwave and Ureteroscopy is a unique and valuable resource in the field of surgical urolithiasis, essential both for those currently in training and for those already in clinical practice.
Histotechnology and histomorphometry are the major methodologies in bone and cartila- related research. Handbook of Histology Methods for Bone and Cartilage is an outgrowth of the editors' own quest for information on bone and cartilage histology and histomorphometry. It is designed to be an experimental guide for personnel who work in the areas of basic and clinical bone and cartilage, orthopedic, or dental research. It is the first inclusive and organized reference book on histological and histomorphometrical techniques on bone and cartilage specimens. The topic has not previously been covered adequately by any existing books in the field. Handbook of Histology Methods for Bone and Cartilage has six major parts and is designed to be concise as well as inclusive, and more practical than theoretical. The text is simple and straightforward. Large numbers of tables, line drawings, and micro- or macro-photographs, are used to help readers better understand the content. Full bibliographies at the end of each chapter guide readers to more detailed information. A book of this length cannot discuss every method for bone and cartilage histology that has been used over the years, but it is hoped that major methods and their applications have been included.
This book offers a thorough and accessible look into the importance of recovery in both staying healthy and performing well, and highlights the detrimental effects of underrecovery on physical and mental health. Internationally renowned experts from psychology, physiology, sport medicine, health, and sport science offer interdisciplinary analysis of the effects of underrecovery as well as the use of applied intervention and prevention strategies. Over the last few decades, research in sports has provided numerous studies showing the importance of addressing recovery to find recovery-stress balance and build resources that help prevent illness and promote healthy living and well-being. Each chapter of this volume discusses a specific area of recovery, providing a collection of useful and practical lessons athletes and non-athletes can take forward in their training and beyond. Focusing on both research and applied counseling techniques to discuss recovery as an underestimated factor in physical and mental health, the book aims to enlighten readers on ways to incorporate recovery into their everyday lives to reduce stress and prevent injury. The book is written for the scientific community, applied health scientists, students, and interested readers. It draws on experiences and scientific findings from the field of sport to make them usable for an expanded understanding of recovery in the field of health and related areas such as the workplace.
Botox continues to be the number one cosmetic procedure performed worldwide. Physicians from a wide range of specialties - not just dermatologists but also OBGYNs, primary care practitioners and ophthalmologists - are eager to learn from results-focused educational material written by leading practitioners. Most botox books focus solely on injection technique. Handbook of Botulinum Toxins for Aesthetic Indications: Theory and Practice describes current techniques, but focuses on securing optimum results in different patient types, e.g. patients of different ethnicities, patients with thick skin, heavy brows, and so on. In addition, the book covers hot topics such as the use of new types of neurotoxins, the problem of counterfeit products, and combining neurotoxins with other modalities such as fillers and lasers. Edited by a recognized educator in this area, and taking a unique problem-based approach, Handbook of Botulinum Toxins for Aesthetic Indications gives practical guidance on the use of different strategies in different patient types to ensure the best possible aesthetic results. Unique, practical emphasis on treatment strategies for different patient types Includes coverage of new neurotoxins recently approved for use Highly illustrated with colour photographs and detailed drawings showing injection sites and technique Written by well-known educators in dermatologic surgery
Today, over 500,000 patients have been treated world wide in 250 Gamma Knife Centres in 37 countries each one treating between 150 and 700 patients a year. The current book serves as a textbook, training manual and reference book for those involved in Gamma Knife practice covering the theoretical background, the practical aspects of treatment, the social side of the method and necessary information not only for users but for those who refer to the Gamma Knife. It also covers some aspects of the hospital and social administration required for optimal use of the technology, also looking at the effect of the internet on specialist medical practice. It also presents the completely new Gamma Knife (Perfexion), a new technology which extends the range of the Gamma Knife and will be the treatment standard for the future.
Bronchiolitis Obliterans Syndrome in Lung Transplantation presents the most current and up-to-date evidence regarding the diagnosis and management of BOS. In-depth chapters provide readers with a comprehensive understanding of the definition and changing perceptions of the nature of BOS as a clinical and pathologic entity, immune and non-immune mechanisms that have been identified as risk factors for the development of BOS, and interventions that may prove to be clinically useful for the prevention or treatment of BOS. In addition to outlining the current state of knowledge, each chapter provides the reader with the most current and ongoing research in the field as well as identifies areas where future research is needed. Written by an international group of expert authors, Bronchiolitis Obliterans Syndrome in Lung Transplantation is an important new text, that is essential reading for pulmonologists, primary care practitioners, respiratory care practitioners and clinical researchers.
This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM's role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.
Written by neurosurgery residents for neurosurgery residents, The Neurosurgical Consult Book focuses on the initial care and treatment of the neurosurgical consult patient, providing the key guidance you need when quick clinical management decisions are critical. You'll learn to recognize the acuity of patient presentation and determine how to immediately triage the needs of the patient at an appropriate level of care. This portable, practical guide helps you quickly steer neurosurgical patients to medical stability and safety until a definitive clinical management plan is determined. Features a real-life approach, based on actual consults, with chapters titled by the symptoms and clinical presentation of the patient, not by neurosurgical diagnosis. Begins each chapter with the actual consult notification from the consulting team, mimicking how the neurosurgery provider is notified about a new patient in practice. Presents initial imaging as it occurs in real life-whether imaging has already been done or whether the consulting physician needs guidance on what imaging is needed. Includes "Walking Thoughts", guidance on how to tailor your thoughts toward the most important and pressing issues facing the patients before even meeting them, so that upon evaluation, the most important questions are asked first. Covers the most essential neurosurgical grading scales, key physical exam findings, the systematic thought process behind triage management, and learning points to remember when seeing a particular type of neurosurgical patient. Summarizes evidence-based standards of care and key literature. Stepwise video demonstration of the most common emergent bedside procedures. An excellent learning tool for neurosurgery residents as well as neurosurgery fellows, neurology residents, emergency room providers, neurocritical care providers, registered nurses, clinical fellows, physician assistants, nurse practitioners, clinical nurse specialists, medical students, and nursing students. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, videos, and references from the book on a variety of devices. |
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Samden D. Lhatoo, Philippe Kahane, …
Hardcover
R8,291
Discovery Miles 82 910
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