This book provides an expert view into the current technologies that are revolutionizing the field of solid organ transplantation. This unique book provides insight into progress made in areas spanning robotic surgery to tissue engineering and also gives a glimpse into what may lie ahead for this innovative specialty. Topics covered include nanotherapy, machine perfusion, artificial organ development, robotics in transplant surgery, mobile health technology, stem cell therapy, and ex vivo repair of organs. This is an ideal book for biomedical engineers, physicians and surgeons, general and transplant surgeons, medical students, medical and surgical trainees, and transplant procurement technicians.

For the thousands of people affected by severe obesity, the decision to undergo weight loss surgery can be a matter of life and death. But it is not a simple procedure. That's why, for many, the decision does not come easily. To help you make the best possible choice, a dynamic team of experts have come together to share their experience, knowledge, and findings about these procedures. Merle Cantor Goldberg is one of this country's leading psychotherapists specializing in eating disorders; Drs. Cowan and Marcus have helped develop many of the techniques used in bariatric surgery, and have also taught these procedures to hundreds of other surgeons. "Weight Loss Surgery begins by asking important questions that must be considered before any decision is made. It then presents a comprehensive overview of pre-op visits, the various weight loss surgeries available, and the post-op recovery period, examining both the psychological and the physical impacts of the surgery. Weight loss surgery is not a minor procedure, but when appropriate, it can save lives. This thoughtful book offers the information you need to make the decision that's right for you.

This Recent Results in Cancer Research volume provides an up-to-date overview of the multidisciplinary management of locally confined rectal cancer as well as colorectal cancer with synchronous resectable liver metastases. The contents comprise the majority of the invited contributions from the Second St. Gallen EORTC Gastrointestinal Cancer Conference, held on 6-8 March 2014 in St. Gallen, Switzerland. Written by some of the world s leading experts in the imaging, endoscopy, pathology, molecular biology, surgery, radiotherapy and medical oncology of rectal cancer and liver metastases, the chapters offer a comprehensive view on the latest recommendations in diagnosis and multidisciplinary treatment. Every clinician involved in the care of patients with rectal cancer will find this book interesting and helpful."

In this book, world-renowned experts describe the latest advances in minimally invasive gynecologic surgery and explain why endoscopy is of key importance in so many conditions. Hysteroscopic instrumentation is described and the application of hysteroscopic techniques in patients with polyps, fibroids, malformations and infertility is explained and evaluated. Individual chapters are devoted to the current minimally invasive treatment of endometriosis, endometrial polyps and adenomyosis. The role of laparoscopy in gynecologic oncology and the laparoscopic approach to hysterectomy are fully discussed. Various other applications of laparoscopy are considered, with coverage of techniques including traditional straight stick laparoscopy, barbed suture and robotic and single port surgery. Neurophysiology and the use of laparoscopic therapy to restore vital function are discussed and complications of laparoscopic surgery are also addressed.

General Principles of Tumor Immunotherapy: Basic and Clinical Applications of Tumor Immunology brings together the world's leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.

Surgery of the Rheumatoid Hand and Wrist is a text book providing an up-to- date overview of the modern surgical treatments to the hand and wrist of patients suffering with inflammatory arthritis. Soft tissue deformity and joint replacement are treated throughout the book with a presentation of the latest design of implants for the wrist and fingers, written by design surgeons. Also included are a number of discussions with regard to various types of arthroplasty as related to the various clinical presentations. Modern up- to-date surgical principles and surgical techniques addressing problems in inflammatory arthritis of the hand and wrist. Long term role of surgery is addressed. Contributions from world renowned surgeons.

This book, which describes in detail the most common procedures employed in inguinal hernia surgery, is exceptional in reflecting fully the most recent advances, as well as the most established techniques, in knowledge and practice. The role of recently developed and emerging technologies, including robotics, minimally invasive surgery, and biological meshes, is clearly explained, highlighting useful tips and tricks. The descriptions of traditional procedures, such as the Lichtenstein repair, are brought fully up to date and take into account the novel perceptions that professionals have of them, for example regarding the important role of nurses. The reader will also find guidance on established and new treatments for specific pain conditions, including postoperative chronic pain, the pubic inguinal pain syndrome, and obscure groin pain in women. The need for such an update on inguinal hernia surgery became clear at the 1st World Conference on Abdominal Wall Hernia Surgery, which highlighted the huge differences in the approaches adopted by scientists around the world and was chaired by the editor of this book. Inguinal Hernia Surgery will be a useful tool for all health care practitioners involved in hernia surgery.

"Perioperative Addiction" addresses an issue that every anesthesiologist will encounter many times during the course of his or her career: the patient who arrives for operative care under the influence of legal or illegal drugs. The editors and contributors provide expert guidance on how to identify and manage the addicted patient, approaching the subject from the vantage points of the specific drug and of special patient populations.

Features:

Guidance for spotting and managing addicted patients

All common and important drugs of addiction, from opioids, cocaine, club drugs, and alcohol, to tobacco, marijuana, nitrous oxide, inhalants, and propofol

Special populations, including pregnant women, pain patients, adolescents, older patients, and healthcare professionals

Fascinating overview of the long history of addiction

Genetic basis of addiction, and the range of pharmacological treatments for addiction

This book explains the concept of metabolic surgery and provides step-by-step descriptions of all the principal minimally invasive surgical techniques employed to treat morbid obesity. The approach adopted is very practical. For each procedure, indications, technical aspects, clinical management and outcomes are described and helpful tips and tricks, highlighted. Guidance is provided on the management of emergencies and potential complications, as well as on general postoperative management and long-term follow-up. The coverage also includes new frontiers of robotic and endoscopic surgery. While the focus is on surgical techniques, emphasis is placed on the need for a multidisciplinary approach, with explanation of the role of the multidisciplinary team and the bariatric center. In addition, important information is presented on the definition of morbid and severe obesity, incidence/prevalence, pathophysiology and obesity-related comorbidities. The authors are internationally acknowledged experts who present best practice know-how in the field and draw on the most recent research literature.

In the last two decades, tremendous strides in the field of mechanical support have extended the lives of countless sufferers of congestive heart failure, who total close to 1% of the US population. This technology has saved the lives of patients with acute heart failure due to heart attacks, dilated cardiomyopathies and post-cardiotomy shock and sustained patients with end stage congestive heart failure until a precious donor organ has become available for transplantation. In an attempt to address the growing imbalance between demand and supply of donor hearts, and armed with great hope and excitement, investigators are now examining these devices as potential alternatives to cardiac transplantation.

This book describes in detail the historical evolution, current knowledge, and future trends in the field of mechanical circulatory support. It will be of greatest interest to cardiologists, circulatory physiologists, cardiac anaesthesiologists, critical care physicians, cardiac surgeons, and other healthcare professionals who are challenged daily with the care of patients with acute and chronic heart failure.

Biomaterials for Surgical Operation offers a review of the latest advances made in developing bioabsorbable devices for surgical operations which include surgical adhesives (sealants), barriers for the prevention of tissue adhesion, polymers for fractured bone fixation, growth factors for the promotion of wound healing, and sutures. Over the years, many descriptions of biomaterials have appeared in academic journals and books, but most of them have been devoted to limited clinical areas. This is in marked contrast with this volume which covers a wide range of bioabsorbable devices used in surgery from a practical point of view. The currently applied polymeric devices are critical in surgery, but all involve serious problems due to their poor performance. For instance, fibrin glue, the most widely used surgical sealant, can produce only a weak gel with low adhesive strength to tissues, accentuating the limited effectiveness of current treatment options. Likewise, the currently available barrier membranes cannot fully prevent tissue adhesion at the acceptable level and are, moreover, not easy to handle with endoscopes due to their poor mechanical properties. Biomaterials for Surgical Operation is aimed at those who are interested in expanding their knowledge of how the problems associated with the currently used devices for surgical operation can be solved. It primarily focuses on the absorbable biomaterials which are the main components of these medical devices.

This popular and successful book, having been translated into major languages, has now been fully revised, updated and expanded into a third edition. The text: provides a step by step guide to all the commonly performed procedures and techniques includes the very latest information on new techniques and materials, such as those for cosmetic surgery contains new chapters covering techniques and management of corneal exposure is extensively illustrated with clear line diagrams to illustrate all the procedures described there is an expanded chapter on lacrimal surgery by Mr Richard Welham still retains its original aim to provide a systematic approach and an invaluable practical guide for all those who operate on eyelids From the reviews of previous editions: 'Collin has managed to include those extremely pertinent points which are important to the operating surgeon... the book is full of a wealth of information on eyelid surgical procedures.' Plastic and Reconstructive Surgery '...a really excellent book packed with detail... I would recommend that a copy of this book be kept in all eye theatres...' Journal of the Irish College of Physicians and Surgeons The most efficient, hands-on resource of its kind. Provides step-by-step guidance on most of the commonly performed surgical procedures and techniques Clear line diagrams illustrate all of the procedures described. Systematically organized for quick and easy reference. New coverage of ectropion adjustable sutures in ptosis surgery, eyelid tumor management and clearance, thyroid eye disease, orbital implants and socket surgery, new coverage of the management of lower lid blepharoplasty and more.

PNL is the gold standard for the management of large and/or otherwise complex renal stones. Since its introduction in the seventies PNL has undergone considerable evolution, mainly driven by the improvement in access techniques, endoscopic instrument technology, lithotripsy devices and drainage management. The conventional prone position for PNL has been challenged in the last two decades by a variety of modifications, including the supine and Galdakao-modified supine Valdivia positions, which make simultaneous retrograde working access to the collecting system possible and have proven anesthesiological advantages. The Galdakao-modified supine Valdivia position allowed the development of ECIRS (Endoscopic Combined IntraRenal Surgery), a technique exploiting a combined antegrade and retrograde approach to the upper urinary tract, using both rigid and flexible endoscopes with the related accessories. The synergistic teamwork of ECIRS provides a safe and efficient, minimally-invasive procedure for the treatment of all kinds of urolithiasis. The aim of this book is to share with the urologic community worldwide our experience, our standardization of all the steps, and tips and tricks for the procedure.

This book has been written step wise by enumerating various aspects of the importance of clinical examination derived by laying one's hands on the affected part. By a thorough clinical examination, it can help an individual to arrive at a tentative differential diagnosis of the condition and hence help in investigating the same by numerous tests which are relevant to the given condition. The manner in which a given case is handled in this way is far more important than the diagnosis of the condition and this feature comes with practicing the same many times. It is a must for anyone embarking in life on Orthopedics as a career.

Taking a multidisciplinary approach to a common and often frustrating problem for athletes and those with an active lifestyle, this book is the first of its kind, addressing muscular injuries to the posterior leg using an in-depth and expansive style that is uniquely dedicated to ensuring all content is explicitly linked to the practical care of patients with calf pain. It is divided thematically into three sections. The first section covers underlying principles involved in these issues, including anatomy, physiology, pathophysiology of injury and neurophysiology of musculoskeletal pain. Clinical assessment techniques and imaging are covered in the second section. The third section on treatment is the most expansive, discussing acute, sub-acute and chronic posterior leg muscle injuries, as well as surgical management, rehabilitation techniques, complementary medicine and special populations. Overall, the book is designed to use muscular injuries of the posterior leg to as a means to understand the assessment and treatment of muscular injuries more broadly. Taken together, it is the consummate source for orthopedists, doctors in sports medicine, podiatrists, rehabilitation professionals and primary care physicians who treat muscular injuries in the posterior leg, though reader will gain a conceptual and practical framework for the assessment and treatment of muscular injuries in general.

Part of the new Core Knowledge in Orthopaedics series, this new resource provides concise and practical coverage of the most essential knowledge in orthopaedics and sports medicine for infants and children. It opens with a review of the differences between the pediatric and adult skeletons, and continues with a chapter covering physical examination techniques for paediatric patients. The book then explores a broad range of individual orthopaedic problems and disorders. Abundant tables, algorithms, and specially designed diagrams assist readers in mastering key concepts quickly and efficiently. Covers all areas of pediatric orthopaedics, including upper and lower extremity disorders, injuries, and deformities * musculoskeletal infections * muscular dystrophy and arthrogryposis * sports medicine * spina bifida * synovial disorders * trauma * cerebral palsy and neuromuscular disorders * and more. Uses concise, bullet-point text with numerous charts, tables, and algorithms to expedite reference. Features a wealth of outstanding illustrations, original drawings, and clinically relevant radiographs. Offers lists of bibliographical sources at the end of each chapter. With 26 additional contributing experts

This text takes a comprehensive approach to rotator cuff disorders, including tears and arthroscopic techniques in surgical management. It addresses the latest topics, such as the conversion of mini-open repair to all arthroscopic repair, and answers key questions raised at instructional courses. Experts in the field present not only arthroscopic shoulder anatomy, cuff tear patterns, repair concepts, and other fundamentals, but also provide coverage of state-of-the-art techniques. The step-by-step approach is supplemented by a wealth of anatomical drawings and color photos.

This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

This book offers a comprehensive guide to total knee arthroplasty (TKA) that will assist in achieving excellent outcomes based on a sound understanding and technique. After an introductory section on the native knee that covers the anatomy, physiology, biomechanics, and patterns of disease, all aspects of primary knee arthroplasty are discussed in detail. Individual chapters are devoted to topics such as acute pain management, the role of technological aids, prosthetic kinematics, alignment targets, unicompartmental arthroplasty, patellar resurfacing, outcome measures, and cost-effectiveness. An extensive section explains the causes and management of potential complications, including aseptic failure, infections, and periprosthetic fracture. The surgical techniques appropriate for revision knee arthroplasty are described separately, and guidelines on how to deal with bone loss, instability, and extensor mechanism failure are provided. The authors are all respected experts from the United Kingdom, United States, Australia and Europe.

The philosophy of management of skeletal tuberculosis has been greatly influenced by the availability of effective antitubercular drugs, facility of modern imaging modalities for diagnosis at predestructive stages of disease, and changes in the socioeconomic status of the people. Techniques have evolved to retain and restore the mobility of articular disease. The looming challenge of ""super-bugs"" has been addressed with possible modalities to combat it by immunopotentiating techniques. The sixth edition is a compilation of the personal clinical experience of the author and relevant information from the international literature. Many new pictures have been added mostly as ""composites"" to express the story as it evolves in clinical management. This book is a source of knowledge of biological processes of activity and healing of disease, and for rational options for effective and safe management of tuberculosis of the skeletal system. This book will guide the learner to master the concepts in tuberculosis of the skeletal system. Includes most recent information on the subject along with philosophy behind investigations and treatment of musculoskeletal tuberculosis. Divided into three sections- General Consideration, Extra-spinal Regional Tuberculosis, and Tuberculosis of the Spine. Conclude with Take Home Key Points.

Every day, newspapers and television news programs present stories on the latest controversies over healthcare and medical advances, but they do not have the space to provide detailed background on the issues. Websites and weblogs provide information from activists and partisans intent on presenting their side of a story. But where can students - or even ordinary citizens - go to obtain unbiased, detailed background on the medical issues affecting their daily lives? This volume in the Health and Medical Issues Today series provides readers and researchers a balanced, in-depth introduction to the medical, scientific, legal, and cultural issues surrounding organ tranplants and its import in today's world of healthcare. Organ Transplantation is organized to provide readers with easy access to the information they need: BLSection 1 provides overview chapters on the background information needed to intelligently understand the issues and controversies surrounding organ transplants, such as how organs are procured and who determines who gets an organ. BLSection 2 offers capsule examinations of the contemporary issues and debates that provoke the most heated disagreements and misunderstandings, such as controversies over who deserves to get an organ, and the concerns over xenotransplantation BLSection 3 includes reference material on organ transplantation, including primary source documents from important players in the debates, a timeline of important events, and an annotated bibliography of useful print and electronic resources. This volume in the Health and Medicine Today series provides everything a student requires to understand the issues involved in organ transplantation and provides aspringboard for further research into the issue

Rapid prototyping is used to design and develop medical devices and instrumentation. This book details research in rapid prototyping of bio-materials for medical applications. It provides a wide variety of examples of medical applications using rapid prototyping, including tissue engineering, dental applications, and bone replacement. Coverage also discusses the emergence of computer aided design in the development of prosthetic devices.

Deciding on cometic surgery should not be like buying a used car. Magazines, television shows, and advertisements have bombarded the average person with unrealistic or totally wrong information. Reality TV shows such as Extreme Makeover, I Want a Famous Face, or Dr. 90210 create hype about cosmetic surgery, but do not always convey realistic expectations or realistic results. Dr. Christopher Saunders weeds through the misinformation and focuses on education and easy concepts: the "Real-Reality" of cosmetic surgery. In an easy to read, informative, and thorough manner Dr. Saunders presents cosmetic surgery topics that focus on realistic options, realistic recovery, and realistic results that he calls the "Real-Reality." From the consultation, to the actual cosmetic operation, and everything in between, Dr. Saunders filters out the used-car sales pitch and hype pushed by many doctors and companies. Dr. Saunders uses a concise and clear voice in his book to outline key concepts about the "Real-Reality" of cosmetic surgery. If you are considering cosmetic surgery or have questions about the topic, this is a must read and important educational source.