This issue of the Surgical Oncology Clinics will cover the following topics: imaging for pancreatic cancer, EUS staging and novel therapeutics for pancreatic cancer, management of cystic tumors, management of IPMN, laparoscopic surgery for pancreatic tumors, current concepts in the surgical management of pancreatic cancer, management of borderline resectable pancreatic cancer, regionalization of pancreatic surgery, update on adjuvant trials for pancreatic cancer, neoadjuvant therapy for pancreatic cancer, novel targets for pancreatic cancer therapy, and new frontiers in pancreatic cancer.

Hypermobility of Joints 4th Edition follows the same format as its successful predecessors. The aim of which was to provide an overview of hyperlaxity of joints and this edition follows that aim by describing the most recent research and new developments in biochemistry, as well as providing practical advice on clinical features and management.

Hypermobility of Joints 4th Edition provides illustrative case histories, a review of hypermobility in the performing arts and sports and an outline of heritable hypermobility syndromes. This book is a valuable reference tool for a wide number of specialties, although it will particularly be of interest to rheumatologists, orthopedic surgeons and medical geneticists.

This issue discusses aesthetic reconstruction principles and techniques for the face that has been damaged by disease or trauma. It includes articles on reconstruction of scalp, forehead, eyelid, cheek, nose, and lip defects; endoscopic surgery for the lacrimal duct; prelamination and prefabrication applications; lipofilling; facial transplantation; surgical treatment and radiation therapy for facial skin cancer; and improving outcomes in aesthetic facial reconstruction.

Vascular Anatomy: The Head, Neck and Skull Base; Neurovascular Anatomy of the Brain and Skull; Vascular Anatomy of the Spine and Spinal Cord; Intracranial Collateral Anastomoses - Relevance to Endovascular Procedures; CT Imaging, MR Imaging and Ultrasound; Applications to Endovascular Procedures; Techniques and Devices in Neuroendovascular Procedures; Percutaneous Vertebroplasty; Inferior Petrosal Sinus Sampling in the Diagnosis of Sellar Neuropathology; Physiological Testing; Balloon Occlusion Testing, and WADA Testing in Neuroendovascular Procedures

This volume of Advances and Technical Standards in Neurosurgery covers some important new developments in functional neurosurgery and endovascular therapy. In the Technical Standards section a variety of topics are considered, including optic pathway gliomas, pineal lesions, cavernous sinus meningiomas and the eternal problem of minor and repetitive head injury. Endovascular treatment of a variety of lesions is now common practice and the state of the art in endovascular treatment for acute ischemic stroke is reviewed. An appraisal of the evidence on whether there is a place for microsurgical vascular decompression for essential hypertension raises interesting questions. The volume is completed by contributions on neurosurgical treatment of cluster headaches and occipital nerve stimulation.

This issue of the Surgical Clinics of North America covers a broad spectrum of anorectal disease such as basic anatomy, physiology, and testing of the anorectal region, as well as the most current diagnostic and management strategies for many of the common anorectal conditions encountered by surgeons including hemorrhoids, anal fissures, abscess and fistula.? Also presented are new techniques in the management of pilonidal disease, perianal infections including HIV and condyloma, pruritis ani, and anal stenosis--difficult conditions that often are frustrating for patient and surgeon alike.? Two articles are dedicated to the current management of anorectal Crohn's disease and rectovaginal fistulas, including the evolving multidisciplinary approach.? In addition, advances in the evaluation and current management of retrorectal tumors and anal neoplasms including the role of local excision and transanal endoscopic microsurgery for selected rectal tumors are covered.? Rounding out this issue are approaches to the difficult situation of anorectal trauma including foreign body management, as well as two articles dedicated to the evaluation of pelvic floor disorders and fecal incontinence.

An important review on obstructive sleep apnea for the oral and maxillofacial surgeon! Topics include epidemiology, pathophysiology and clinical features of obstructive sleep apnea; systematic evaluation of the OSA patient; upper airway imaging in the evaluation and surgical management of OSA; management of OSA by continuous positive airway pressure; oral appliances in the treatment of OSA; algorithms for surgical management of obstructive sleep apnea; surgery of the palate, tonsils and tongue; treatment of OSA by distraction osteogenesis; surgical management of OSA in the pediatric patient; anesthetic and postoperative management of the OSA patient, and much more!

For this issue, Dr. Michael Lim of Johns Hopkins and Dr. Isaac Yang of UCSF team up to deliver a packed issue on the latest developments in Immunotherapy.? The issue covers hot topics such as immunostimulants, Passive Antibody Mediated Immunotherapy, Clinical Applications of A Peptide Based Vaccine, Challenges for Clinical Design of Immunotherapy Trials, The EGFRv3 Peptide Vaccine, Stem Cell Therapy and Dendritic Cell Vaccines, Dendritic Glioma Fusion Vaccine, Adoptive Cellular Immunotherapy, Virus Mediated Immunotherapy, and so much more.

Intraductal papillary mucinous neoplasms (IPMNs) represent an opportunity to treat pancreatic tumors before they develop into aggressive, hard-to-treat cancers. Beginning with morphological classification and its clinical significance, natural history, and malignant change of both main duct and branch duct IPMNs, this book covers the whole field of IPMNs of the pancreas. It reviews the various methods of investigation: imaging, diagnostic investigation of cyst fluid, and those using pancreatic juice; and also examines aspects ranging from the development of malignancy to the timing and method of resection, focusing on both main duct and branch duct IPMNs.

Aimed at residents, clinical fellows, and pancreatologists who treat patients with this common disease of the pancreas, this book is a landmark in the current understanding and future perspectives of IPMNs of the pancreas.

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Proposed topics for this issue include: Demographics and Workforce in issues in Rural Surgery; Measuring Quality in Rural Surgery; Education of the Rural Surgeon (Models from Oregon, Wisconsin, Tennessee, MIBH); Rural Surgery - the Australian experience; Working Models (Oklahoma, Iowa, North Dakota); Starting a Rural Surgical Program from Scratch; The Importance of Rural Surgery - The primary care perspective; The Financial Impact of a Rural Surgeon on a Hospital.

Guest Editor Adam Landsman covers the broad spectrum of advances in wound healing in podiatric medicine. Topics include: "An update on advanced products used to aid in the wound and bone healing," "A histologic analysis of soft tissue interactions with collagen bioscaffolds; are they all the same?" " The role of collagen bioscaffolds, foamed collagen and living skin equivalents in wound healing," "Augmentation of Atrophic Plantar Soft-Tissue with an Acellular Regenerative Dermal Allograft: A Case Series Review," and more!

In the 10 years since malignant melanoma was last covered in Clinics in Plastic Surgery, significant changes have occurred in the diagnosis and treatment of this disease.? Sentinel lymph node biopsy has now become the standard of care in melanoma. The staging system was totally revamped in 2002, taking into account the significance of ulceration and the information gained during sentinel node biopsy.? With more than 60,000 patients diagnosed each year with malignant melanoma, the plastic surgeon must continue to be pivotal in the management of patients with this disease, coordinating care among the specialists and being integral in all aspects of surgery and follow-up.

Topics include: Concomitant Resurfacing and Facial Implants in Facelift; Complications of Facelift; Anesthesia and Facility in Facelift; Concomitant Fillers in Facelift; Short Scar Vertical U Lift; Deep Plane Facelift; SMAS Facelift Technique; Neck Contouring; Facelift and the Heavy Face; Male Facelift; Pearls in Facelift Management.

The use of interventional endoscopy of the biliary and pancreatic ducts has increased dramatically in recent years. Although choledocholithiasis is the most common reason for endoscopic treatment, other indications include pancreatolithiasis, cholangitis, biliary pancreatitis, papillary stenosis, sphincter of Oddi dysfunction, and benign or malignant ductal strictures. The Guest Editor has assembled an issue full of expert authors to present state-of-the art information biliary and pancreatic endoscopy procedures and techniques.

This issue of the Surgical Oncology Clinics will review the important clinical trials from the past eight years in following topics: breast cancer, soft tissue sarcoma, rectal and anal carcinoma, pancreatic adenocarcinoma, hepatocellular carcinoma, gastric cancer, esophageal cancer, colon cancer, advanced and metastatic colorectal carcinoma, gastrointestinal stromal tumors, and melanoma.

The Epidemiology, Clinical features and Natural History of Emphysema; The National Emphysema Treatment Trial (NETT); 'Rationale and Experience for Staged Lung Volume Reduction Surgery' Rationale and Experience for Staged Lung Volume Reduction Surgery; Lung Volume Reduction Surgery for Non-Heterogenous Emphysema; Lung Volume Reduction Surgery for Alpha-1-Antripsin Emphysema; Concomitant Lung Cancer Resection and Lung Volume Reduction Surgery; Concomitant Cardiac Surgery and Lung Volume Reduction Surgery; Decision Making in the Management of Secondary Pneumothorax in Patients with Severe Emphysema; Intraoperative and Postoperative Management of Pulmonary Alveolar Air Leaks in Thoracic Surgery; Airway Bypass Treatment of Severe Homogenous Emphysema; Treatment of Heterogenous Emphysema Using The Spiration IBV Intrabronchial Valves; Treatment of Heterogenous Emphysema Using The Emphasys Zephyr EBV Endobronchial Valves; Update on Donor Assessment, Resuscitation and Acceptance Criteria; Update on Lung Transplantation for End Stage Emphysema

Topics include: Evaluation and initial management of the patient with facial skin cancer; Nonmelanomatous skin cancer; Mohs, Malignant melanoma; Local flaps - bilobed, rhombic, forehead, melolabial; Options for the management of scalp defects; Defects of the nose; Eyelid defects; Ear defects; Defects of the lips; Cheek defects; Secondary procedures to improve flap appearance.

It's always been said, "Children are not young adults," and the examination of a child needs to be conducted with emphasis on the physiologic differences in a growing child. Clinical Orthopedic Examination of a Child focuses on pediatric examination, a topic not much explored in the regular orthopedic texts. A child's difficulty in verbally expressing his symptoms needs to be kept in mind during the examination, thus the examining surgeon has to be very observant in picking up even minor details that could help in diagnosis. This book serves as an essential companion to orthopedic surgeons, general practitioners, and professionals as well as being a welcome addition in pediatric orthopedic clinics. Key Features Reviews an unexplored topic of Pediatric Orthopedic examination with comprehensive clarity Has an algorithmic approach with step-by-step descriptions, complete with illustrations Provides helpful tips and insights to orthopedic surgeons, professionals, and trainees for accurate diagnosis and treatment

Articles include: "Functional Anatomy of the Gastroc-Soleus Complex and Achilles Tendon, ? "Insertional Achilles Tendinosis and Posterior Heel Pain Pathology, ? "Non-Insertional Achilles Tendinosis Conservative, ? "Non-Surgical Management of Achilles Tendon Ruptures, ? "Acute Open Repair of the Ruptures Achilles Tendon, ? "Minimal Incision Techniques for Acute Achilles Repair, ? "Rehabilitation of the Achilles Tendon, ? "Tendon Transfers for Achilles Reconstruction, ? "Management of Chronic Achilles Deficiency, ? "Complications of Achilles Tendon Surgery, ? "Achilles Lengthening Procedures - Indications, Techniques, ? "Emerging Techniques, ? "Posterior Calf Injury and Pain (conditions that mimic Achilles

The effects of hand burn injuries can be critical to quality of life and crucial to long-term functional outcomes following burn injury. Since hands are at the front line of human contact, a high percentage of thermal injury involves the upper extremity and, in particular, the hand. Hand burns can vary in severity from shallow burns requiring local wound care and aggressive range of motion therapy to complex wounds requiring repair of joints, tendons, and other soft tissue. Historically, given the poor survival associated with severe burn injury, many patients with hand burns simply did not survive the acute phase of treatment. If patients survived the systemic insult of burn injury, often the hands were neglected relative to more extensive areas on the trunk. However, with the widespread use of early excision and grafting, as well as great advancements in critical care, survival following thermal injury has become the rule rather than the exception. Therefore, emphasis in burn care has shifted towards optimizing the functional and psychosocial outcomes of those that survive their injury. Accordingly, optimal management of hand burns has received increasing attention given the critical importance of hand recovery to long-term outcome. In this volume of Hand Clinics, experts in burn care present an overview of pediatric and adult hand burn management - including shallow burns, as well as complex injuries from deep thermal burns or electrical injury. In addition, chapters on pathphysiology of scar, burn hand rehabilitation and assessing outcomes of hand injury emphasize critical concepts in achieving optimal hand function after injury.

Articles include: "Percutaneous Plating of Proximal Humeral Fractures, ? "Mini Incision Surface Replacement of the Humeral Head, ? "Mini Incision Carpal Tunnel Release, ? "MIS Hueter-Gaine Approach for THA, ? "MIS Approach for Hip Resurfacing, ? "MIS Unicondylar Arthroplasty: Mini Open and Arthroscopic Approach, ? "MIS Total Knee Arthroplasty, ? "Minimally Invasive Hallux Valgus Correction, ? "Percutaneous CT Guided Vertebroplasty in the Management of Osteoporotic Fractures and Dorso Lumbar Metastases, ? "Minimally Invasive Spinal Surgery, ? "Percutaneously Assisted Hip Arthroplasty, ? "MIS THA using a Watson-Jones A