Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Through clear descriptions and color images, this volume illustrates how noninvasive imaging is used to track stem cells as they repair damaged tissue in the body. With contributions from some of the most prominent preclinical and clinical researchers in the field, the book helps readers to understand the evolving concepts of stem cell labeling and tracking as the field continues to move forward.

Engineering systems and products are an important element of the world economy and each year billions of dollars are spent to develop, manufacture, operate, and maintain systems and products around the globe. Because of this, global competition is requiring reliability professionals to work closely with other departments involved in engineering development during the product design and manufacturing phase. Applied Reliability for Engineers is an attempt to meet the need for a single volume that addresses a wide range of applied reliability topics. The material is treated in such a manner that the reader will require no previous knowledge to understand the text. The sources of most of the information presented are given in a reference section at the end of each chapter. At appropriate places, the book contains examples along with their solutions. At the end of each chapter there are numerous problems to test reader comprehension. This volume is thus suitable for use as a textbook as well as for reference. Applied Reliability for Engineers is useful to design professionals, system engineers, reliability specialists, graduate and senior undergraduate students, researchers and instructors of reliability engineering, and engineers-at-large.

This handbook offers a comprehensive overview of cloud computing security technology and implementation while exploring practical solutions to a wide range of cloud computing security issues. As more organizations use cloud computing and cloud providers for data operations, the need for proper security in these and other potentially vulnerable areas has become a global priority for organizations of all sizes. Research efforts from academia and industry, as conducted and reported by experts in all aspects of security related to cloud computing, are gathered within one reference guide. Features * Covers patching and configuration vulnerabilities of a cloud server * Evaluates methods for data encryption and long-term storage in a cloud server * Demonstrates how to verify identity using a certificate chain and how to detect inappropriate changes to data or system configurations John R. Vacca is an information technology consultant and internationally known author of more than 600 articles in the areas of advanced storage, computer security, and aerospace technology. John was also a configuration management specialist, computer specialist, and the computer security official (CSO) for NASA's space station program (Freedom) and the International Space Station Program from 1988 until his retirement from NASA in 1995.

The present work showcases a novel approach to modeling systems architectures by utilizing Lego bricks and RFID technology. The presented solution can be used by systems and software architects to communicate their design decisions with other stakeholders in the developments process such as customers and managers involved. The software provided in this book helps to get a concrete tool showing how the approach can be applied. If the reader is interested in experimenting with this approach, they will need to purchase LEGO (c) blocks and the required RFID technology needed for this.

With the rapid advancement of information discovery techniques, machine learning and data mining continue to play a significant role in cybersecurity. Although several conferences, workshops, and journals focus on the fragmented research topics in this area, there has been no single interdisciplinary resource on past and current works and possible paths for future research in this area. This book fills this need. From basic concepts in machine learning and data mining to advanced problems in the machine learning domain, Data Mining and Machine Learning in Cybersecurity provides a unified reference for specific machine learning solutions to cybersecurity problems. It supplies a foundation in cybersecurity fundamentals and surveys contemporary challenges-detailing cutting-edge machine learning and data mining techniques. It also: Unveils cutting-edge techniques for detecting new attacks Contains in-depth discussions of machine learning solutions to detection problems Categorizes methods for detecting, scanning, and profiling intrusions and anomalies Surveys contemporary cybersecurity problems and unveils state-of-the-art machine learning and data mining solutions Details privacy-preserving data mining methods This interdisciplinary resource includes technique review tables that allow for speedy access to common cybersecurity problems and associated data mining methods. Numerous illustrative figures help readers visualize the workflow of complex techniques and more than forty case studies provide a clear understanding of the design and application of data mining and machine learning techniques in cybersecurity.

Ubiquitous in today's consumer-driven society, embedded systems use microprocessors that are hidden in our everyday products and designed to perform specific tasks. Effective use of these embedded systems requires engineers to be proficient in all phases of this effort, from planning, design, and analysis to manufacturing and marketing. Taking a systems-level approach, Real-Time Embedded Systems: Optimization, Synthesis, and Networking describes the field from three distinct aspects that make up the three major trends in current embedded system design. The first section of the text examines optimization in real-time embedded systems. The authors present scheduling algorithms in multi-core embedded systems, instruct on a robust measurement against the inaccurate information that can exist in embedded systems, and discuss potential problems of heterogeneous optimization. The second section focuses on synthesis-level approaches for embedded systems, including a scheduling algorithm for phase change memory and scratch pad memory and a treatment of thermal-aware multiprocessor synthesis technology. The final section looks at networking with a focus on task scheduling in both a wireless sensor network and cloud computing. It examines the merging of networking and embedded systems and the resulting evolution of a new type of system known as the cyber physical system (CPS). Encouraging readers to discover how the computer interacts with its environment, Real-Time Embedded Systems provides a sound introduction to the design, manufacturing, marketing, and future directions of this important tool.

Assistive technologies for the old and people with disabilities is now a very active field of research. It also constitutes a very profitable market (expected to reach US $60 billion p.a. by 2018). The book covers key aspects of this important field and provides guidelines for developing assistive technologies in smart environments. The book also presents the new paradigm of open innovation used by the most prolific research teams around the world. The latest developments in the field are given. Overall this book will be a reference for researchers, practitioners and engineers.

For the last two decades, IS researchers have conducted empirical studies leading to a better understanding of the impact of Systems Analysis and Design methods in business, managerial, and cultural contexts. SA&D research has established a balanced focus not only on technical issues, but also on organizational and social issues in the information society..This volume presents the very latest, state-of-the-art research by well-known figures in the field. The chapters are grouped into three categories: techniques, methodologies, and approaches.

A well-rounded, accessible exposition of honeypots in wired and wireless networks, this book addresses the topic from a variety of perspectives. Following a strong theoretical foundation, case studies enhance the practical understanding of the subject. The book covers the latest technology in information security and honeypots, including honeytokens, honeynets, and honeyfarms. Additional topics include denial of service, viruses, worms, phishing, and virtual honeypots and forensics. The book also discusses practical implementations and the current state of research.

Computational Intelligence Assisted Design framework mobilises computational resources, makes use of multiple Computational Intelligence (CI) algorithms and reduces computational costs. This book provides examples of real-world applications of technology. Case studies have been used to show the integration of services, cloud, big data technology and space missions. It focuses on computational modelling of biological and natural intelligent systems, encompassing swarm intelligence, fuzzy systems, artificial neutral networks, artificial immune systems and evolutionary computation. This book provides readers with wide-scale information on CI paradigms and algorithms, inviting readers to implement and problem solve real-world, complex problems within the CI development framework. This implementation framework will enable readers to tackle new problems without difficulty through a few tested MATLAB source codes

This book presents both the importance of energy transition and its associated difficulties. Energy Transition, Second Edition, provides an explanation of the physical concepts of energy and power and also reviews global energy consumption and our dependence on energy. The book discusses the links between the economy and energy. It explains the drawbacks and dangers of different energy sources and tries to compare them. By reviewing future energy resources, it evaluates several transition scenarios. The book shows that the laws of physics prevent the emergence of simple, pleasant solutions, but it proposes potential solutions and encourages readers to develop better processes from energy sources to production to consumption. This book will be of interest to engineers and undergraduate and graduate students studying and working in various fields of energy; producers of fossil, gas, oil, coal, electric, renewable, and nuclear energy; and anyone interested in better understanding these fundamental problems for our future. FEATURES Discusses the current issues with energy transition Covers several energy transition scenarios and their associated difficulties Presents the links between economy and energy Highlights the importance of a global discussion of energy Encourages the development of better, improved processes in energy sources from production to consumption

Patients are increasingly encouraged to take an active role in managing their health and health care. New technologies, cultural shifts, trends in healthcare delivery, and policies have brought to the forefront the "work" patients, families, and other non-professionals perform in pursuit of health. Volume I provides a theoretical and methodological foundation for the emerging discipline of Patient Ergonomics - the science of patient work. The Patient Factor: Theories and Methods for Patient Ergonomics, Volume I defines Patient Ergonomics, explains its importance, and situates it in a broader historical and societal context. It reviews applicable theories and methods from human factors/ergonomics and related disciplines, across domains including consumer technology, patient-professional communication, self-care, and patient safety. The Patient Factor is ideal for academics working in health care and patient-centered research, their students, human factors practitioners working in healthcare organizations or at technology companies, frontline healthcare professionals, and leaders of healthcare delivery organizations.

Patients are increasingly encouraged to take an active role in managing their health and health care. New technologies, cultural shifts, trends in healthcare delivery, and policies have brought to the forefront the "work" patients, families, and other non-professionals perform in the pursuit of health. This volume closely examines notable application areas for the emerging discipline of Patient Ergonomics - the science of patient work. The Patient Factor: Applications of Patient Ergonomics, Volume II reviews the definition of Patient Ergonomics and discusses the application of Patient Ergonomics across contexts. It analyzes patient work performed in emergency departments, transitions of care, home and community settings, retail pharmacies, and online communities. It also examines applications to groups including veterans, pediatric patients, older adults, the underserved, and people engaged in health promotion. The Patient Factor is ideal for academics working in health care and patient-centered research, their students, human factors practitioners working in healthcare organizations or at technology companies, frontline healthcare professionals, and leaders of healthcare delivery organizations.

In considering ways that physics has helped advance biology and medicine, what typically comes to mind are the various tools used by researchers and clinicians. We think of the optics put to work in microscopes, endoscopes, and lasers; the advanced diagnostics permitted through magnetic, x-ray, and ultrasound imaging; and even the nanotools, that allow us to tinker with molecules. We build these instruments in accordance with the closest thing to absolute truths we know, the laws of physics, but seldom do we apply those same constants of physics to the study of our own carbon-based beings, such as fluidics applied to the flow of blood, or the laws of motion and energy applied to working muscle. Instead of considering one aspect or the other, Handbook of Physics in Medicine and Biology explores the full gamut of physics' relationship to biology and medicine in more than 40 chapters, written by experts from the lab to the clinic. The book begins with a basic description of specific biological features and delves into the physics of explicit anatomical structures starting with the cell. Later chapters look at the body's senses, organs, and systems, continuing to explain biological functions in the language of physics. The text then details various analytical modalities such as imaging and diagnostic methods. A final section turns to future perspectives related to tissue engineering, including the biophysics of prostheses and regenerative medicine. The editor's approach throughout is to address the major healthcare challenges, including tissue engineering and reproductive medicine, as well as development of artificial organs and prosthetic devices. The contents are organized by organ type and biological function, which is given a clear description in terms of electric, mechanical, thermodynamic, and hydrodynamic properties. In addition to the physical descriptions, each chapter discusses principles of related clinical diagnostic method

This book is a collection of accepted papers that were presented at the International Conference on Communication and Computing Systems (ICCCS-2016), Dronacharya College of Engineering, Gurgaon, September 9-11, 2016. The purpose of the conference was to provide a platform for interaction between scientists from industry, academia and other areas of society to discuss the current advancements in the field of communication and computing systems. The papers submitted to the proceedings were peer-reviewed by 2-3 expert referees. This volume contains 5 main subject areas: 1. Signal and Image Processing, 2. Communication & Computer Networks, 3. Soft Computing, Intelligent System, Machine Vision and Artificial Neural Network, 4. VLSI & Embedded System, 5. Software Engineering and Emerging Technologies.

This text identifies, examines, and illustrates fundamental concepts in computer system design that are common across operating systems, networks, database systems, distributed systems, programming languages, software engineering, security, fault tolerance, and architecture. Through carefully analyzed case studies from each of these disciplines, it demonstrates how to apply these concepts to tackle practical system design problems. To support the focus on design, the text identifies and explains abstractions that have proven successful in practice such as, remote procedure call, client/service organization, file systems, data integrity, consistency, and authenticated messages. Most computer systems are built using a handful of such abstractions. The text describes how these abstractions are implemented, demonstrates how they are used in different systems, and prepares the reader to apply them in future designs.

This unique book is offered in an online / offline split: Chapters 1-6 are included in the book available from Morgan Kaufmann in print or ebook form. Chapters 7-11 are available online under a Creative Commons license. Download them for free at http: //www.elsevierdirect.com/companion.jsp?ISBN=9780123749574
Features:
Concepts of computer system design guided by fundamental principles.Cross-cutting approach that identifies abstractions common to networking, operating systems, transaction systems, distributed systems, architecture, and software engineering.Case studies that make the abstractions real: naming (DNS and the URL); file systems (the UNIX file system); clients and services (NFS); virtualization (virtual machines); scheduling (disk arms); security (TLS).Numerous pseudocode fragments that provide concrete examples of abstract concepts.Extensive support. The authors and MIT OpenCourseWare provide on-line, free of charge, open educational resources, including additional chapters, course syllabi, board layouts and slides, lecture videos, and an archive of lecture schedules, class assignments, and design projects."

Written by an industry insider with state of the art research at their fingertips, this book describes the Radio Access Network (RAN) architecture, starting with currently deployed 4G, followed by the description of 5G requirements and why re-thinking of the RAN architecture is needed to support these. Based on these considerations, it explains how 5G network architecture, which is currently being defined, is likely to evolve. The aim is not merely to cover relevant standards and technologies as a purely academic exercise (although a significant part of the book will be dedicated to these), but to augment these by practical deployment, to illustrate why the RAN architecture is changing and where it is going. With 5G deployments on the horizon, there is a desire within companies to both re-think the RAN architecture and to change the proprietary nature of the RAN. Correspondingly, there is increased interest in academia, standards bodies and commercial entities involved in the area.

Most books on linear systems for undergraduates cover discrete and continuous systems material together in a single volume. Such books also include topics in discrete and continuous filter design, and discrete and continuous state-space representations. However, with this magnitude of coverage, the student typically gets a little of both discrete and continuous linear systems but not enough of either. Minimal coverage of discrete linear systems material is acceptable provided that there is ample coverage of continuous linear systems. On the other hand, minimal coverage of continuous linear systems does no justice to either of the two areas. Under the best of circumstances, a student needs a solid background in both these subjects. Continuous linear systems and discrete linear systems are broad topics and each merit a single book devoted to the respective subject matter. The objective of this set of two volumes is to present the needed material for each at the undergraduate level, and present the required material using MATLAB (R) (The MathWorks Inc.).

For courses in structured systems analysis and design. Prioritising the practical over the technical, Modern Systems Analysis and Design presents the concepts, skills, methodologies, techniques, tools, and perspectives essential for systems analysts to develop information systems. The authors assume students have taken an introductory course on computer systems and have experience designing programs in at least one programming language. By drawing on the systems development life cycle, the authors provide a conceptual and systematic framework while progressing through topics logically. The 9th edition has been completely revised to adapt to the changing environment for systems development, with a renewed focus on agile methodologies.

Embedded Software Development: The Open-Source Approach delivers a practical introduction to embedded software development, with a focus on open-source components. This programmer-centric book is written in a way that enables even novice practitioners to grasp the development process as a whole. Incorporating real code fragments and explicit, real-world open-source operating system references (in particular, FreeRTOS) throughout, the text: Defines the role and purpose of embedded systems, describing their internal structure and interfacing with software development tools Examines the inner workings of the GNU compiler collection (GCC)-based software development system or, in other words, toolchain Presents software execution models that can be adopted profitably to model and express concurrency Addresses the basic nomenclature, models, and concepts related to task-based scheduling algorithms Shows how an open-source protocol stack can be integrated in an embedded system and interfaced with other software components Analyzes the main components of the FreeRTOS Application Programming Interface (API), detailing the implementation of key operating system concepts Discusses advanced topics such as formal verification, model checking, runtime checks, memory corruption, security, and dependability Embedded Software Development: The Open-Source Approach capitalizes on the authors' extensive research on real-time operating systems and communications used in embedded applications, often carried out in strict cooperation with industry. Thus, the book serves as a springboard for further research.

VHDL, the IEEE standard hardware description language for describing digital electronic systems, has recently been revised. This book has become a standard in the industry for learning the features of VHDL and using it to verify hardware designs. This third edition is the first comprehensive book on the market to address the new features of VHDL-2008.
* First comprehensive book on VHDL to incorporate all new features of VHDL-2008, the latest release of the VHDL standard...helps readers get up to speed quickly with new features of the new standard.
* Presents a structured guide to the modeling facilities offered by VHDL...shows how VHDL functions to help design digital systems.
* Includes extensive case studies and source code used to develop testbenches and case study examples..helps readers gain maximum facility with VHDL for design of digital systems.

This book offers a friendly presentation of the fundamental principles and practices of modern digital design. Unlike any other book in this field, transistor-level implementations are also included, which allow the readers to gain a solid understanding of a circuit's real potential and limitations, and to develop a realistic perspective on the practical design of actual integrated circuits. Coverage includes the largest selection available of digital circuits in all categories (combinational, sequential, logical, or arithmetic). Coverage also includes detailed digital design techniques, with a thorough discussion on state-machine modeling for the analysis and design of complex sequential systems. Key technologies used in modern circuits are also described, including Bipolar, MOS, ROM/RAM, and CPLD/FPGA chips, as well as codes and techniques used in data storage and transmission. Designs are illustrated by means of complete, realistic applications using VHDL, where the complete code, comments and simulation results are included.
* Comprehensive coverage of fundamental digital concepts and principles, as well as complete, realistic, industry-standard designs
* Many circuits shown with internal details at the transistor-level, as in real integrated circuits
* Actual technologies used in state-of-the-art digital circuits presented in conjunction with fundamental concepts and principles
* Six chapters dedicated to VHDL-based techniques, with all VHDL-based designs synthesized onto CPLD/FPGA chips

This book has been a long time in the making. The computerization activi ties described in these pages began in 1977 at the Department of Veterans Affairs (VA), but we devoted most of our focus and efforts to building and then implementing the extensive hospital information system known as the Decentralized Hospital Computer System (DHCP) throughout VA. Deliv ering the product has been our primary goal. We spent relatively little time documenting or describing our experiences or lessons learned. Except for some presentations at national meetings and a relatively few publications, almost none of which were in the standard trade journals read by Chief Information Officers (CIOs) and equivalent top managers in the private and nonprofit sectors, VA's accomplishments remained a well-kept secret. In 1988, Helly Orthner encouraged VA staff to consider writing a book, but the press of day-to-day activities always seemed to take precedence, and the book languished on the back burner."

Combining GIS concepts and fundamental spatial thinking methodology with real programming examples, this book introduces popular Python-based tools and their application to solving real-world problems. It elucidates the programming constructs of Python with its high-level toolkits and demonstrates its integration with ArcGIS Theory. Filled with hands-on computer exercises in a logical learning workflow this book promotes increased interactivity between instructors and students while also benefiting professionals in the field with vital knowledge to sharpen their programming skills. Readers receive expert guidance on modules, package management, and handling shapefile formats needed to build their own mini-GIS. Comprehensive and engaging commentary, robust contents, accompanying datasets, and classroom-tested exercises are all housed here to permit users to become competitive in the GIS/IT job market and industry.

In the extensive fields of optics, holography and virtual reality, technology continues to evolve. Displays: Fundamentals and Applications, Second Edition addresses these updates and discusses how real-time computer graphics and vision enable the application and displays of graphical 2D and 3D content. This book explores in detail these technological developments, as well as the shifting techniques behind projection displays, projector-camera systems, stereoscopic and autostereoscopic displays. This new edition contains many updates and additions reflecting the changes in fast developing areas such as holography and near-eye displays for Augmented and Virtual reality applications. Perfect for the student looking to sharpen their developing skill or the master refining their technique, Rolf Hainich and Oliver Bimber help the reader understand the basics of optics, light modulation, visual perception, display technologies, and computer-generated holography. With almost 500 illustrations Displays will help the reader see the field of augmentation and virtual reality display with new eyes. Features: * Covers physics, technology and techniques behind flat-panel as well as projection displays, projector-camera systems, stereoscopic and autostereoscopic displays, computer-generated holography, and near-eye displays * Discusses how real-time computer graphics and computer vision enable the visualization of graphical 2D and 3D content * Augmented by close to 500 rich illustrations, which give readers a clear understanding of existing and emerging display technology