The overwhelming majority of a software system's lifespan is spent in use, not in design or implementation. So, why does conventional wisdom insist that software engineers focus primarily on the design and development of large-scale computing systems? In this collection of essays and articles, key members of Google's Site Reliability Team explain how and why their commitment to the entire lifecycle has enabled the company to successfully build, deploy, monitor, and maintain some of the largest software systems in the world. You'll learn the principles and practices that enable Google engineers to make systems more scalable, reliable, and efficient-lessons directly applicable to your organization. This book is divided into four sections: Introduction-Learn what site reliability engineering is and why it differs from conventional IT industry practices Principles-Examine the patterns, behaviors, and areas of concern that influence the work of a site reliability engineer (SRE) Practices-Understand the theory and practice of an SRE's day-to-day work: building and operating large distributed computing systems Management-Explore Google's best practices for training, communication, and meetings that your organization can use

Design Journeys for Complex Systems is a designer's handbook to learn systemic design tools to engage stakeholder groups in collaborative design to address complex societal systems. Systemic design uses systems thinking and service design to address large-scale societal contexts and complex socio-technical systems. These are contexts characterized by social and technological complexity, high uncertainty, and often problematic outcomes. Using a tour guide metaphor, the book trains people's mindsets and provides tools for dealing with hyper complexity, to enable understanding of systemic problems, and to build capacity to collaborate in teams to produce action proposals.

Since its first volume in 1960, Advances in Computers has presented detailed coverage of innovations in computer hardware, software, theory, design, and applications. It has also provided contributors with a medium in which they can explore their subjects in greater depth and breadth than journal articles usually allow. As a result, many articles have become standard references that continue to be of significant, lasting value in this rapidly expanding field.

Control Engineering and Information Systems contains the papers presented at the 2014 International Conference on Control Engineering and Information Systems (ICCEIS 2014, Yueyang, Hunan, China, 20-22 June 2014). All major aspects of the theory and applications of control engineering and information systems are addressed, including: - Intelligent systems - Teaching cases - Pattern recognition - Industry application - Machine learning - Systems science and systems engineering - Data mining - Optimization - Business process management - Evolution of public sector ICT - IS economics - IS security and privacy - Personal data markets - Wireless ad hoc and sensor networks - Database and system security - Application of spatial information system - Other related areas Control Engineering and Information Systems provides a valuable source of information for scholars, researchers and academics in control engineering and information systems.

Modern-day projects require software and systems engineers to work together in realizing architectures of large and complex software-intensive systems. To date, the two have used their own tools and methods to deal with similar issues when it comes to the requirements, design, testing, maintenance, and evolution of these architectures. Software and Systems Architecture in Action explores practices that can be helpful in the development of architectures of large-scale systems in which software is a major component. Examining the synergies that exist between the disciplines of software and systems engineering, it presents concepts, techniques, and methods for creating and documenting architectures. The book describes an approach to architecture design that is driven from systemic quality attributes determined from both the business and technical goals of the system, rather than just its functional requirements. This architecture-centric design approach utilizes analytically derived patterns and tactics for quality attributes that inform the architect's design choices and help shape the architecture of a given system. The book includes coverage of techniques used to assess the impact of architecture-centric design on the structural complexity of a system. After reading the book, you will understand how to create architectures of systems and assess their ability to meet the business goals of your organization. Ideal for anyone involved with large and complex software-intensive systems, the book details powerful methods for engaging the software and systems engineers on your team. The book is also suitable for use in undergraduate and graduate-level courses on software and systems architecture as it exposes students to the concepts and techniques used to create and manage architectures of software-intensive systems.

Shaped by Quantum Theory, Technology, and the Genomics Revolution

The integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents recent fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, students, and clinical providers. The third volume, Therapeutics and Advanced Biophotonics, focuses on therapeutic modalities, advanced biophotonic technologies, and future trends.

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Represents the Collective Work of over 150 Scientists, Engineers, and Clinicians"

Designed to display the most recent advances in instrumentation and methods, as well as clinical applications in important areas of biomedical photonics to a broad audience, this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of medical technologies.

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What s New in This Edition: "

A wide variety of photonic biochemical sensing technologies has already been developed for clinical monitoring of early disease states and physiological parameters, such as blood pressure, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics, proteomics, and metabolomics allow sensing of early disease states, thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of disease, imaging single molecules and "in situ "diagnostics at the single-cell level. In addition to these state-of-the-art advancements, the second edition contains new topics and chapters including:

Fiber Optic Probe Design

Laser and Optical Radiation Safety

Photothermal Detection

Multidimensional Fluorescence Imaging

Surface Plasmon Resonance Imaging

Molecular Contrast Optical Coherence Tomography

Multiscale Photoacoustics

Polarized Light for Medical Diagnostics

Quantitative Diffuse Reflectance Imaging

Interferometric Light Scattering

Nonlinear Interferometric Vibrational Imaging

Nanoscintillator-Based Therapy

SERS Molecular Sentinel Nanoprobes

Plasmonic Coupling Interference Nanoprobes

Comprised of three books: Volume I: Fundamentals, Devices, and Techniques; Volume II: Biomedical Diagnostics; and Volume III: Therapeutics and Advanced Biophotonics, this second edition contains eight sections, and provides introductory material in each chapter. It also includes an overview of the topic, an extensive collection of spectroscopic data, and a list of references for further reading."

As the complexity of today s networked computer systems grows, they become increasingly difficult to understand, predict, and control. Addressing these challenges requires new approaches to building these systems. Adaptive, Dynamic, and Resilient Systems supplies readers with various perspectives of the critical infrastructure that systems of networked computers rely on. It introduces the key issues, describes their interrelationships, and presents new research in support of these areas.
The book presents the insights of a different group of international experts in each chapter. Reporting on recent developments in adaptive systems, it begins with a survey of application fields. It explains the requirements of such fields in terms of adaptation and resilience. It also provides some abstract relationship graphs that illustrate the key attributes of distributed systems to supply you with a better understanding of these factors and their dependencies.
The text examines resilient adaptive systems from the perspectives of mobile, infrastructure, and enterprise systems and protecting critical infrastructure. It details various approaches for building adaptive, dynamic, and resilient systems including agile, grid, and autonomic computing; multi-agent-based and biologically inspired approaches; and self-organizing systems.
The book includes many stories of successful applications that illustrate a diversified range of cutting-edge approaches. It concludes by covering related topics and techniques that can help to boost adaptation and resilience in your systems."

There are essentially two theories of solutions that can be considered exact: the McMillan-Mayer theory and Fluctuation Solution Theory (FST). The first is mostly limited to solutes at low concentrations, while FST has no such issue. It is an exact theory that can be applied to any stable solution regardless of the number of components and their concentrations, and the types of molecules and their sizes. Fluctuation Theory of Solutions: Applications in Chemistry, Chemical Engineering, and Biophysics outlines the general concepts and theoretical basis of FST and provides a range of applications described by experts in chemistry, chemical engineering, and biophysics. The book, which begins with a historical perspective and an introductory chapter, includes a basic derivation for more casual readers. It is then devoted to providing new and very recent applications of FST. The first application chapters focus on simple model, binary, and ternary systems, using FST to explain their thermodynamic properties and the concept of preferential solvation. Later chapters illustrate the use of FST to develop more accurate potential functions for simulation, describe new approaches to elucidate microheterogeneities in solutions, and present an overview of solvation in new and model systems, including those under critical conditions. Expert contributors also discuss the use of FST to model solute solubility in a variety of systems. The final chapters present a series of biological applications that illustrate the use of FST to study cosolvent effects on proteins and their implications for protein folding. With the application of FST to study biological systems now well established, and given the continuing developments in computer hardware and software increasing the range of potential applications, FST provides a rigorous and useful approach for understanding a wide array of solution properties. This book outlines those approaches, and their advantages, ac

Informational Macrodynamics (IMD) presents the unified information systemic approach with common information language for modeling, analysis and optimization of a variety of interactive processes, such as physical, biological, economical, social, and informational, including human activities. Comparing it with thermodynamics, which deals with transformation energy and represents a theoretical foundation of physical technology, IMD deals with transformation information, and can be considered a theoretical foundation of Information Computer Technology (ICT). ICT includes but is not limited to applied computer science, computer information systems, computer and data communications, software engineering, and artificial intelligence. In ICT, information flows from different data sources, and interacts to create new information products. The information flows may interact physically or via their virtual connections, initiating an information dynamic process that can be distributed in space. As in physics, a problem is understanding general regularities of the information processes in terms of information law, for the engineering and technological design, control, optimization, and development of computer technology, operations, manipulations, and management of real information objects. Information Systems Analysis and Modeling: An Informational Macrodynamics Approach belongs to an interdisciplinary science that represents the new theoretical and computer-based methodology for system informational description and improvement, including various activities in such interdisciplinary areas as thinking, intelligent processes, management, and other nonphysical subjects with their mutual interactions, informational superimpositions, and the information transferred between interactions. Information Systems Analysis and Modeling: An Informational Macrodynamics Approach can be used as a textbook or secondary text in courses on computer science, engineering, business, management, education, and psychology and as a reference for research and industry.

Service computing is a cutting-edge area, popular in both industry and academia. New challenges have been introduced to develop service-oriented systems with high assurance requirements. High Assurance Services Computing captures and makes accessible the most recent practical developments in service-oriented high-assurance systems.

An edited volume contributed by well-established researchers in this field worldwide, this book reports the best current practices and emerging methods in the areas of service-oriented techniques for high assurance systems. Available results from industry and government, R&D laboratories and academia are included, along with unreported results from the hands-on experiences of software professionals in the respective domains.

Designed for practitioners and researchers working for industrial organizations and government agencies, High Assurance Services Computing is also suitable for advanced-level students in computer science and engineering."

This book, presented in three volumes, examines environmental disciplines in relation to major players in contemporary science: Big Data, artificial intelligence and cloud computing. Today, there is a real sense of urgency regarding the evolution of computer technology, the ever-increasing volume of data, threats to our climate and the sustainable development of our planet. As such, we need to reduce technology just as much as we need to bridge the global socio-economic gap between the North and South; between universal free access to data (open data) and free software (open source). In this book, we pay particular attention to certain environmental subjects, in order to enrich our understanding of cloud computing. These subjects are: erosion; urban air pollution and atmospheric pollution in Southeast Asia; melting permafrost (causing the accelerated release of soil organic carbon in the atmosphere); alert systems of environmental hazards (such as forest fires, prospective modeling of socio-spatial practices and land use); and web fountains of geographical data. Finally, this book asks the question: in order to find a pattern in the data, how do we move from a traditional computing model-based world to pure mathematical research? After thorough examination of this topic, we conclude that this goal is both transdisciplinary and achievable.

This book, presented in three volumes, examines environmental disciplines in relation to major players in contemporary science: Big Data, artificial intelligence and cloud computing. Today, there is a real sense of urgency regarding the evolution of computer technology, the ever-increasing volume of data, threats to our climate and the sustainable development of our planet. As such, we need to reduce technology just as much as we need to bridge the global socio-economic gap between the North and South; between universal free access to data (open data) and free software (open source). In this book, we pay particular attention to certain environmental subjects, in order to enrich our understanding of cloud computing. These subjects are: erosion; urban air pollution and atmospheric pollution in Southeast Asia; melting permafrost (causing the accelerated release of soil organic carbon in the atmosphere); alert systems of environmental hazards (such as forest fires, prospective modeling of socio-spatial practices and land use); and web fountains of geographical data. Finally, this book asks the question: in order to find a pattern in the data, how do we move from a traditional computing model-based world to pure mathematical research? After thorough examination of this topic, we conclude that this goal is both transdisciplinary and achievable.

Kubernetes has become the operating system of today's cloud native world, providing a reliable and scalable platform for running containerized workloads. In this friendly, pragmatic book, cloud experts Justin Domingus and John Arundel show you what Kubernetes can do-and what you can do with it. This updated second edition guides you through the growing Kubernetes ecosystem and provides practical solutions to everyday problems with software tools currently in use. You'll walk through an example containerized application running in Kubernetes step-by-step, from the development environment through the continuous deployment pipeline, exploring patterns you can use for your own applications. Make your development teams lean, fast, and effective by adopting Kubernetes and DevOps principles. Understand containers and Kubernetes-no experience necessary Run your own applications on managed cloud Kubernetes services or on-prem environments Design your own cloud native services and infrastructure Use Kubernetes to manage resource usage and the container lifecycle Optimize clusters for cost, performance, resilience, capacity, and scalability Learn the best tools for developing, testing, and deploying your applications Apply the latest industry practices for observability and monitoring Secure your containers and clusters in production

The long-standing cultural imperative of augmenting human intellect continues to move ever closer to its full manifestation, described by Marshall McLuhan as an extension of the human nervous system. The escalating blending of immersive technologies with advanced computation has created an emerging domain which increasingly allows socio-technical system makers to produce not only human-computer interactions, but advanced, multi-minded human+computer (H+C) systems. The critical shift toward user immersion within systems of digital information and simulation makes the scale of immersive media's potential impact on human life, culture and well-being unlike that of any previous medium. In Designing XR, Peter (Zak) Zakrzewski presents H+C immersion as a multi-dimensional design problem - a Research Through Design (RTD) zone which addresses the question of: How can transformative design-thinking-based knowledge system complement the existing human-computer interaction (HCI) invention model to contribute to the creation of more participatory, socially viable, and humane immersive media environments? The book lays out a proposal for ushering the creation of ecologically sound augmented mind based on two essential tasks. The first involves a framework for the design, implementation, and iteration of purposeful, multi-minded, participatory immersive H+C systems. The second focuses on the extended reality experience (XRX) design practice that rhetorically invites users to actively engage with immersive systems while fully exercising their autonomy and agency based on informed choice.

The European Conference on Computer and Network Defense draws contributions and participation both from academia and industry, and addresses security from multiple perspectives, including state-of-the-art research in computer network security, intrusion detection, denial-of-service, privacy protection, security policies, and incident response & management. The conference is organized jointly by the Institute of Computer Science of the Foundation for Research and Technology - Hellas (FORTH) and the European Network and Information Security Agency (ENISA).

Microcontroller Programming: An Introduction is a comprehensive one-stop resource that covers the concepts, principles, solution development, and associated techniques involved in microcontroller-based systems. Focusing on the elements and features of the popular and powerful Motorola 68HC11 microcontroller IC as a representative example, this book is unlike others, which are often too broad in scope, delving into every topic of concern regarding microcontroller programmers. Instead, this text concentrates on design, architecture, and development, giving developers the tools to develop solid, effective embedded applications. Packaged with helpful examples, projects, and illustrations, this book gives an in-depth assessment of microcontroller design programming in both assembly and C. By illustrating the relatively sophisticated 8-bit 68HC11 microcontroller, the author-who is a consultant for NASA-provides a firsthand exploration and demonstration of the languages, tools, and techniques needed to build embedded applications. Readers can then apply their newly acquired skills to program other 8/16/32-bit microcontrollers. For readers who want to do more than just scrape the surface, this book is an enjoyable and immensely beneficial tool to help them cultivate a deeper understanding of microcontroller-based application development. An extensive supplements package is available free of charge to instructors who use the book for a course.

Advances such as cloud computing and streaming multimedia are steadily increasing the demand on network resources, and telecommunications providers must ensure that their networks are managed effectively in order to ensure that Internet and mobile users remain satisfied with their quality of service. Network and Traffic Engineering in Emerging Distributed Computing Applications focuses on network management and traffic engineering for Internet and distributed computing technologies, as well as present emerging technology trends and advanced platforms. This premier reference source for academics, students, researchers, readers, and knowledge seekers puts together some of the critical aspects of Internet and distributed systems.

A hands-on introduction to VHDL synthesis and FPGA prototyping

Hardware Descriptive Language (HDL) and Field Programmable Gate Array (FPGA) devices

allow designers to quickly develop and simulate a sophisticated digital circuit, realize it on a prototyping device, and verify the operation of its physical implementation. As these technologies have matured, they have become accepted mainstream practice so that it is possible to use a PC and an inexpensive FPGA prototyping board to construct a complex digital system.

This book uses a "learn by doing" approach to introduce the concepts and techniques of VHDL and FPGA to designers through a series of hands-on experiments. FPGA Prototyping by VHDL Examples provides:

A collection of clear, easy-to-follow templates for quick code development

A large number of practical examples to illustrate and reinforce the concepts and design techniques

Realistic projects that can be implemented and tested on a Xilinx prototyping board

A thorough exploration of the Xilinx PicoBlaze soft-core microcontroller

Although the book is an introductory text, the examples are developed in a rigorous manner and the derivations follow strict design guidelines and coding practices used for large, complex systems. It lays a solid foundation for students and new engineers and prepares them for future development tasks. FPGA Prototyping by VHDL Examples is an indispensable companion text for introductory digital design courses and also serves as a valuable self-teaching guide for practicing engineers who wish to learn more about this emerging area of interest.

The TransNav 2011 Symposium held at the Gdynia Maritime University, Poland in June 2011 has brought together a wide range of participants from all over the world. The program has offered a variety of contributions, allowing to look at many aspects of the navigational safety from various different points of view. Topics presented and discussed at the Symposium were: navigation, safety at sea, sea transportation, education of navigators and simulator-based training, sea traffic engineering, ship's manoeuvrability, integrated systems, electronic charts systems, satellite, radio-navigation and anti-collision systems and many others. This book is part of a series of six volumes and provides an overview of Human Resources and Crew Resource management and is addressed to scientists and professionals involved in research and development of navigation, safety of navigation and sea transportation.

Because of the continuous evolution of integrated circuit manufacturing (ICM) and design for manufacturability (DfM), most books on the subject are obsolete before they even go to press. That's why the field requires a reference that takes the focus off of numbers and concentrates more on larger economic concepts than on technical details. Semiconductors: Integrated Circuit Design for Manufacturability covers the gradual evolution of integrated circuit design (ICD) as a basis to propose strategies for improving return-on-investment (ROI) for ICD in manufacturing. Where most books put the spotlight on detailed engineering enhancements and their implications for device functionality, in contrast, this one offers, among other things, crucial, valuable historical background and roadmapping, all illustrated with examples. Presents actual test cases that illustrate product challenges, examine possible solution strategies, and demonstrate how to select and implement the right one This book shows that DfM is a powerful generic engineering concept with potential extending beyond its usual application in automated layout enhancements centered on proximity correction and pattern density. This material explores the concept of ICD for production by breaking down its major steps: product definition, design, layout, and manufacturing. Averting extended discussion of technology, techniques, or specific device dimensions, the author also avoids the clumsy chapter architecture that can hinder other books on this subject. The result is an extremely functional, systematic presentation that simplifies existing approaches to DfM, outlining a clear set of criteria to help readers assess reliability, functionality, and yield. With careful consideration of the economic and technical trade-offs involved in ICD for manufacturing, this reference addresses techniques for physical, electrical, and logical design, keeping coverage fresh and concise for the designers, manufacturers, and researchers defining product architecture and research programs.

The TransNav 2011 Symposium held at the Gdynia Maritime University, Poland in June 2011 has brought together a wide range of participants from all over the world. The program has offered a variety of contributions, allowing to look at many aspects of the navigational safety from various different points of view. Topics presented and discussed at the Symposium were: navigation, safety at sea, sea transportation, education of navigators and simulator-based training, sea traffic engineering, ship's manoeuvrability, integrated systems, electronic charts systems, satellite, radio-navigation and anti-collision systems and many others. This book is part of a series of six volumes and provides an overview of Transport Systems and Processes and is addressed to scientists and professionals involved in research and development of navigation, safety of navigation and sea transportation.

Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of data across scales, and the prediction of tumor progression and treatment outcome (in silico oncology). Drawing on an interdisciplinary group of distinguished international experts, Multiscale Cancer Modeling discusses the scientific and technical expertise necessary to conduct innovative cancer modeling research across scales. It presents contributions from some of the top in silico modeling groups in the United States and Europe. The ultimate goal of multiscale modeling and simulation approaches is their use in clinical practice, such as supporting patient-specific treatment optimization. This volume covers state-of-the-art methods of multiscale cancer modeling and addresses the field's potential as well as future challenges. It encourages collaborations among researchers in various disciplines to achieve breakthroughs in cancer modeling.

As a collection of ideas and methodologies, systems thinking has made an impact in organizations and in particular in the information systems field. However, this main emphasis on organizations limits the scope of systems thinking and practice. There is a need first to use systems thinking in addressing societal problems, and second to enable people involved in developing the information society to reflect on the impacts of systems and technologies in society as a whole. Thus, there are opportunities to review the scope and potential of systems thinking and practice to deal with information society-related issues.

Systems Practice in the Information Society provides students of information systems as well as practicing Inofrmation Systems managers with concepts and strategies to enable them to understand and use systems thinking methodologies and address challenges posed by the development of information-based societies. This book brings experiences, ideas, and applications of systemic thinking in designing and evaluating socio-technological initiatives. Using a number of cultural contexts, this book explores how organizations, including governments, can enable better access to information and communication technologies and improve the quality of life of individuals.

As a collection of ideas and methodologies, systems thinking has made an impact in organizations and in particular in the information systems field. However, this main emphasis on organizations limits the scope of systems thinking and practice. There is a need first to use systems thinking in addressing societal problems, and second to enable people involved in developing the information society to reflect on the impacts of systems and technologies in society as a whole. Thus, there are opportunities to review the scope and potential of systems thinking and practice to deal with information society-related issues.

Systems Practice in the Information Society provides students of information systems as well as practicing Inofrmation Systems managers with concepts and strategies to enable them to understand and use systems thinking methodologies and address challenges posed by the development of information-based societies. This book brings experiences, ideas, and applications of systemic thinking in designing and evaluating socio-technological initiatives. Using a number of cultural contexts, this book explores how organizations, including governments, can enable better access to information and communication technologies and improve the quality of life of individuals.

VerilogA(R) Quickstart is a basic, practical, introductory textbook for professionals and students alike. This book explains how a designer can be more effective through the use of the Verilog hardware description language to simulate and document a design. By understanding simulation, a designer can simulate a design to see if a design works before it is built. This gives the designer an opportunity to try different ideas. Documentation allows a designer to maintain and reuse a design more easily. Verilog's intrinsic hierarchical modularity enables the designer to easily reuse portions of the design as intellectual property' or macro-cells'. VerilogA(R) Quickstart presents some of the formal Verilog syntax and definitions and then shows practical uses. This book does not oversimplify the Verilog language nor does it emphasize theory. VerilogA(R) Quickstart has over 100 examples that are used to illustrate aspects of the language. In the later chapters the focus is on working with modeling style and explaining why and when one would use different elements of the language. Another feature of the book is the chapter on state machine modeling. There is also a chapter on test benches and testing strategy as well as a chapter on debugging. VerilogA(R) Quickstart is designed to teach the Verilog language, to show the designer how to model in Verilog and to explain the basics of using Verilog simulators.