This issue of Veterinary Clinics of North America: Small Animal Practice, edited by Elizabeth Stelow, focuses on Behavior as an Illness Indicator, with topics including: Best Practices in Diagnosing Behavior Problems and Developing Plans to Treat Behavior Problems; Separation, Confinement, or Noises; Managing Canine Aggression in the Home; Diagnosing and Treating Cats Who Urinate Outside the Box; Desensitization and Counterconditioning; Diagnosing Behavior Problems in Older Pets; Behavioral Nutraceuticals and Diets; and Advances in Behavioral Psychopharmacology.

African animal trypanosomosis (AAT), also called nagana, is a trans-boundary disease that has had an immense impact on cattle and is ranked among the top global cattle diseases. This and tick-borne diseases have caused major obstacles to sustainable livestock-based agricultural production and food security and are important factors in underdevelopment. Due to decreasing efficacy of available drugs, widespread trypanosome resistance, and the difficulty of sustaining other control measures, there is a need for alternative sustainable strategies to reduce the impact these diseases have on livestock. Combating and Controlling Nagana and Tick-Borne Diseases in Livestock provides the latest empirical research findings on the effects of African animal trypanosomiasis (nagana) and tick-borne disease infection in livestock, their impact on farmer livelihoods, and the measures that can be undertaken to mitigate negative effects and reduce the number of infections. While highlighting topic areas such as disease history and transmission, treatments, and the economic impacts, this book is essential for farmers, animal health and animal production professionals and practitioners, non-government organizations, researchers, academicians, and students working in fields that include but are not limited to agriculture, livestock production, environmental science, veterinary medicine, veterinary pathology, and epidemiology.

This issue of Veterinary Clinics of North America: Equine Practice focuses on Equine Sports Medicine and includes topics on: Lameness evaluation in the equine athlete; Diagnosis of soft tissue injury in the sport horse; Upper airway conditions affecting the equine athlete; Lower airway conditions affecting the equine athlete; Cardiac/Cardiovascular conditions affecting sport horses; Neck, back, and pelvic pain in sport horses; Neurologic conditions affecting the equine athlete; Metabolic diseases in the equine athlete; Muscle conditions affecting sport horses; Lyme disease in the sport horse; Management and rehabilitation of joint disease in sport horses; Regenerative medicine and rehabilitation for tendinous and ligamentous injuries in sport horses; and Chiropractic and manual therapies.

Environmental Virology, Volume 101, the latest in the Advances in Virus Research series, contains new, informative updates on the topic. First published in 1953, this series covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. Updates to this release include sections on the host landscape and vector behavior, key determinants of plant virus evolution and emergence, plant virome analysis using spatial metagenomics, host range evolution in generalist viruses, the influence of environment, water-mediated spread and transmission of viruses, viruses transmitted by means other than insect vectors, and more.

This book aims to show how film can increase awareness of the plight of farmed animals without exploiting them. Much has been written on the rights of animals, be they in the wild or circuses, hunted, experimented on, used for entertainment, or slaughtered and consumed. However, there has been little that has examined in any detail the filming of farmed animals, and nothing on a declaration of rights for such animals, thus leaving them in a limbo of neglect. Stephen Marcus Finn offers a manifesto on how to foster the rights of farmed animals in filming sets out to rectify this lacuna.

This issue of Veterinary Clinics of North America: Food Animal Practice focuses on Digestive Disorders of the Abomasum and Intestines, with topics including: Diagnostic Approach to the Acute Abdomen; Herd level management of Displaced Abomasum in Dairy Cattle; Abomasal Ulcers in Ruminants; Control and Treatment of Infectious Enteritis; Herd Based Assessment and Control of Salmonella; Enteric Immunity: An Evidence Based Review; Surgical Management of Abomasal and Small Intestinal Disease; Clostridial Abomasitis and Enteritis in Ruminants; Gastro-Intestinal Nematodes, Diagnosis and Contro; and Coccidiosis in Ruminants.

This issue of Veterinary Clinics of North America: Equine Practice focuses on Equine Gastroenterology, and includes topics: Diagnostics and treatment of undifferentiated and infectious acute diarrhea in the adult horse; Foal diarrhea; established and postulated causes, prevention, diagnostics and treatments; Probiotic use in equine gastrointestinal disease; Understanding the intestinal microbiome in health and disease; Advances in diagnostics and treatments in horses with acute colic and postoperative ileus; Advances in diagnostics and treatments in horses and foals with gastric and or duodenal ulcers; Toxic causes of intestinal disease in horses; New perspectives in equine intestinal parasitic disease Diagnostics and Management new insight; Equine disautonomia; Diagnostics and treatments in chronic diarrhea and weight loss in horses; Enteral/parenteral nutrition in foals and adult horses practical guidelines for the practitioner; and Practical fluid therapy and treatment modalities for field conditions for horses and foals with gastro-intestinal problems.

This issue of Veterinary Clinics of North America: Small Animal Practice focuses on Immunology and Vaccination, with topics including: Recent Advances In Vaccine Technologies; Immune System's Response to Vaccination; Current Vaccine Strategies for Dogs and Cats; Update on Therapeutic Vaccines; Common and Newly Recognized Autoimmune Diseases; Adverse Response to Vaccination; Vaccines in Shelters and Group Settings; Evidence vs Belief in Vaccine Recommendations; Effects of Aging on the Immune Response; and Use of Antibody Titer to Determine the Need for Vaccination.

This issue of Veterinary Clinics of North America: Exotic Animal Practice focuses on Therapeutics, with topics including: Metabolic scaling and other methods used to extrapolate drug dosages for exotics; Update on antiviral therapies in birds; Multiresistant bacteria in exotic animal medicine: fact or faux?; Emergency drugs and fluid therapy in exotics; Guidelines for treatment of toxicities in exotic animals; Nutraceuticals in exotic animal medicine; Pharmacokinetic/pharmacodynamics modelling of analgesic drugs; Psychoactive drugs in avian medicine; Cardiovascular drugs in avian and small mammal medicine; Gastrointestinal drugs in small mammal medicine; Update on cancer treatment in exotics; Drug delivery methods with emphasis on low stress handling while medicating exotic animal; and Compounding and extra-label use of drugs in exotic animal medicine.

This issue of Veterinary Clinics of North America: Small Animal Practice on Neurology, edited by Sharon Kerwin and Amanda Taylor, includes: Advances in High field MRI; Acupuncture for neurologic conditions; Head trauma; Pituitary hypophysectomy; Acute non-compressive disc extrusion and hydrated nucleus pulposus extrusion; Discospondylitis; Minimally Invasive Vertebral Column Surgery; Vascular events in the Brain; Fungal infections of the CNS; Feline Seizures; Clinical evaluation of the feline neurologic patient; Intervertebral disc disease, recent advances in therapy; Three-dimensional printing role in neurologic disease; and Diffusion tensor imaging in spinal cord injury.

Many controlled release veterinary drug delivery systems (CRVDDS) are presently in use, and recently there has been a host of new CRVDDS within veterinary medicine. The challenges of this area of drug delivery arise from the unique anatomy and physiology of the target animal, the cost constraints associated with the value of the animal being treated and the extended periods of time that delivery must be sustained for (often measured in months).

The purpose of this book is to introduce the reader to the unique opportunities and challenges of the field of CRVDDS and to explain and discuss the basic controlled release principles underlying the development of CRVDDS. Its aim is to provide an overview of many of the areas where CRVVDS have application, and to highlight the opportunities and prospects for controlled release technology in the veterinary field.

"Controlled Release Veterinary Drug Delivery" comprises chapters that provide workers in the field (and those interested in this area) with information on the design, development and assessment of a variety of CRVDDS. The book contains chapters that describe the relevant animal physiological and anatomical considerations alongside descriptions of current and emerging controlled release delivery systems for a variety of routes for drug delivery, and present overviews on the physical and chemical assessment of veterinary controlled release delivery systems.

The veterinary area is abound with opportunities for the development of controlled release drug delivery technologies. It is an area of medicine that is open to the acceptance of novel drug delivery devices, and which readily encompasses the use of novel routes of administration. It is an area of many unmet needs, most of which offer opportunities and unique challenges for the innovative formulation scientist to provide solutions. This book will provide an insight into the biological, clinical and pharmaceutical challenges that face the formulation scientist in this interesting and diverse area of research.

This issue of Veterinary Clinics of North America: Equine Practice is edited by Dr. Mary Lassaline and focuses on Equine Ophthalmology. Article topics include: Anatomy and Examination; Imaging; Eyelid; Cornea; Uveitis; Lens; Retina with emphasis on electrodiagnostics; Medications Update; Neuro-oph; Ocular neoplasia; Genetic ocular disease, and OMSD with emphasis on borreliosis.

This issue, edited by Drs. Robert Callan and Meredyth Jones, focuses on Digestive Disorders in Ruminants. Article topics include: Rumen (Forestomach) Development and Function; Diagnostic Approach to Forestomach Diseases; Clinical Rumen Acidosis; Diagnosis and Herd Management of Subclinical Rumen Acidosis; Disorders of Rumen Distension and Dysmotility; Diagnosis and Treatment of Hardware Disease; Temporary Rumen Fistula for the Treatment of Forestomach Diseases and Enteral Nutrition; Rumen Microbiome, probiotics, and Fermentation Additives.

The ethical treatment of animals has become an issue of serious moral concern. Many people are challenging long-held assumptions about animals and raising questions about their status and treatment. What is the relationship between humans and animals? Do animals have moral standing? Do we have direct or indirect duties to animals? Does human benefit always outweigh animal suffering? The use of animals for experimentation raises all of these questions in a particularly insistent way. Donna Yarri gives an overview of the current state of the discussion, and presents an argument for significantly restricted animal experimentation. Pointing to the similarities between humans and animals, she argues that the actual differences are differences of degree rather than kind. Animal cognition and animal sentiency together are the basis for the claim that experimental animals do have rights. Examining arguments in the disciplines of ethology, philosophy, science, and theology, Yarri makes a case for placing substantial restrictions on animal experimentation. Grounding her examination in Christian theology, she formulates a more humane approach to animal experimentation. She concludes with a concrete burden-benefit analysis that can serve as the foundation for informed decision-making. The Ethics of Animal Experimentation serves as both a handbook of animal rights theory and a practical guide to navigating the complexities of animal experimentation. As animal experimentation features in an increasing number of scientific endeavors, it is an ethical issue that requires our immediate attention. Yarri's unique contribution forges a path toward an ethical practice of animal experimentation.

This issue of Veterinary Clinics of North America: Exotic Animal Practice on Exotic Animal Neurology, edited by Susan Orosz, includes: Pain and its control in Reptiles; The Neuroanatomical basis for pain and controlling pain in birds; Avian Bornavirus and its pathophysiology for Proventricular dilatation disease; Treatment of Proventricular dilatation disease and avian ganglioneuritis; Vaccination for Proventricular dilatation disease; Imaging the brain for exotic animal clinicians; EC in rabbits; Pain control in small mammals; Vaccination of ferrets for Rabies and Distemper; and Medication for Behavior Modification in Birds.

Quantitative epidemiology provides the principles and tools for a better understanding of disease occurrence and spread in (animal) populations, and in particular, diseases with a multifactoral etiology. This book is based upon the findings from a series of workshops and clinics where theory and practical issues concerning quantitative epidemiological issues were addressed. It is not intended as a textbook, but as an aid to self-training. The book contains detailed examples from the field, and answers are given to questions. The book is aimed primarily at practising veterinarians and animal health workers in the field who wish to improve their quantitative skills. Herd health workers, district veterinary officers and disease control authorities should also find the book useful, as should veterinary and animal science students who are studying population health issues.

Selenium (Se) is an essential dietary trace element participating in the regulation of various physiological functions in both animals and humans through its incorporation into selenoproteins as the amino acid selenocysteine. Among many minerals Se has a special place being the most controversial trace element with a narrow gap between essentiality and toxicity. Indeed there are important environmental issues considering selenium as a pollutant from the one hand and global selenium deficiency on the other. In fact, Se deficiency is considered as a risk factor for the development of various diseases in human and animals. Decreased Se availability from soils as a result of low soil pH and usage of synthetic fertilizers is the major concern in European countries causing inadequate Se levels in food and feeds.Furthermore, it seems likely that sodium selenite used for the last 30 years as a feed supplement is not an optimal form of Se and the usage of organic selenium in animal diets could help to maintain optimal Se status as well as high immunocompetence, productive and reproductive performance. The aim of the present volume is to provide updated information on several important Se-related subjects, including Se status in Europe and ways of its improvement, advances in Se analysis and speciation in biological material, roles of selenium in poultry, pig and ruminant nutrition. In this title, production of functional Se-enriched food, the relationship between selenium and mycotoxins, polyunsaturated fatty acids as well as reoviruses are also addressed. This collection of articles will provide nutritionists, veterinarians, human doctors, researchers and any other readers with new insights into the exciting world of the goddess of the moon - Selenium.

This issue of Veterinary Clinics of North America: Equine Practice is edited by Dr. Ashlee Watts and focuses on Orthopedic Disorders of Foals. Article topics include: Orthopedic conditions of the dysmature foal; Septic arthritis, osteomyelitis and physitis; Club foot; FLD - carpus and fetlock; ALD - growth augmentation; ALD - growth retardation; Foal Fractures - osteochondral fragmentation, sesamoiditis and coffin bone; Foal Fractures - physeal fractures; OCD development; OCD - surgical options and when to utilize them.