The influence of basic science, particularly molecular biology, in human and veterinary medicine revolutionized thinking in many aspects and changed fundamentally and creatively the classical strategy for research and prevention of infectious diseases. Genetic engineering and related disciplines have progressed to a remarkable degree over the last decade and now form the keystone supporting medicine. These are strong and efficient instruments for health and disease oriented research and their application gives the opportunity to receive more answers and not only more questions. The prime objective of this book is to create new knowledge within the medical disciplines and inspire colleagues working in this field with the unity and unambiguous importance of this science and its technologies for identifying, clarifying and planning new strategies for curing and preventing disease. This book contains original studies on the molecular biology of animal viruses. Some of the viruses discussed in this book are also hazardous to man. In this light it can be considered as a contribution to modern education on the human infectious diseases. From this point of view the book contains a chapter on Hantaan virus that causes no detectable disease in animals but hemorrhagic fever with renal syndrome has been attributed to infection of humans by this virus.

Long acting veterinary formulations play a significant role in animal health, production and reproduction within the animal health industry. Such technologies offer beneficial advantages to the veterinarian, farmer and pet owner. These advantages have resulted in them growing in popularity in recent years.

The pharmaceutical scientist is faced with many challenges when innovating new products in this demanding field of controlled release. This book provides the reader with a comprehensive guide on the theories, applications, and challenges associated with the design and development of long acting veterinary formulations. The authoritative chapters of the book are written by some of the leading experts in the field. The book covers a wide scope of areas including the market influences, preformulation, biopharmaceutics, in vitro drug release testing and specification setting to name but a few. It also provides a detailed overview of the major technological advances made in this area. As a result this book covers everything a formulation scientist in industry or academia, or a student needs to know about this unique drug delivery field to advance health, production and reproduction treatment options and benefits for animals worldwide."

A Seminar in the Community Programme for the Coordination of Agricultural Research, held at the Berlaymont Building, Brussels, Belgium, July 5-6, 1988. Sponsored by the Commission of the European Communities, Directorate General for Agriculture, Coordination of Agricultural Research

In this issue of Veterinary Clinics: Small Animal Practice, guest editor Lisa Powell brings her considerable expertise to the topic of Hot Topics in Small Animal Medicine. This issue is an eclectic compilation of some of the most popular topics among readers of this Clinics series. Top experts in the field provide updates on the latest advances and developments in several key areas of importance for small animal practitioners. Contains a variety of relevant, practice-oriented topics including urinary tract infection treatment and comparative therapeutics; acute kidney injury in dogs and cats; fluid and electrolyte therapy during vomiting and diarrhea; basics of mechanical ventilation for dogs and cats; fluid therapy for the emergent small animal patient: crystalloids, colloids, and albumin products; and more. Provides in-depth clinical reviews on hot topics in small animal medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

It takes more than horse sense to maintain a healthy horse. A knowledge of veterinary medicine is essential, not only for when emergencies occur but to provide the animal with a safe and nurturing environment that will prevent as many problems as possible. Acclaimed when first published in 1977 and now available for the first time in paperback, Horseman's Veterinary Encyclopedia offers a comprehensive approach to equine health, discussing diseases, unsoundnesses and other problems according to the parts of the horse's body: injuries and lameness; foot and hoof care; parasites; skin and coat care; colic and other sicknesses; dental care; and the respiratory, circulatory and reproductive systems. As a practical handbook for the owner and as a guide to working with the veterinarian and farrier, Horseman's Veterinary Encyclopedia is an indispensable tool for every home, barn, and ranch. The highly acclaimed reference on equine medical treatment and preventive care. It takes more than horse sense to maintain a healthy horse. A knowledge of veterinary medicine is essential, not only for when emergencies occur but also to provide the animal with a safe and nurturing environment that will prevent as many problems as possible. Acclaimed when first published in 1977, and now thoroughly updated with the latest veterinary advances, Horseman's Veterinary Encyclopedia, Revised and Updated, offers a comprehensive approach to equine health, discussing disease, unsoundness, and other problems according to the parts of the horse's body: injuries and lameness; foot and hoof care; parasites; skin and coat care; colic and other sicknesses; infectious diseases such as West Nile virus; dental care; and the respiratory, circulatory and reproductive systems. As a practical handbook for the owner and as a guide to working with the veterinarian and farrier, Horseman's Veterinary Encyclopedia, Revised and Updated, is an indispensable tool for every home, stable, and ranch.

G. Petursson and Rikke Hoff-J0rgensen The concept of slow viral infections was first put forward in 1954 by Dr. Bjorn Sigurdsson, an Icelandic physician who had been studying some sheep diseases which were introduced into Iceland with the importation of a foreign breed of sheep in 1933. Sigurdsson's main criteria for defining slow infec tions were a very long initial period without clinical signs lasting months or even years following infection and a rather regular protracted, progres sive course, once clinical symptoms had appeared, usually ending in serious disease or death. Sigurdsson included in this list of slow infections maedi -visna, infectious adenomatosis of sheep, scrapie in sheep, Bittner's mam mary carcinoma and Gross' leukemia in mice. All of these diseases, except scrapie, are caused by retroviruses. The characteristics of slow infections as described above are of prac tical importance for epidemiology, diagnosis and control of these diseases. For many years the slow infections remained primarily a veterinary problem, mainly affecting sheep and goats in certain countries. In recent years, how ever, the human immunodeficiency virus (HIV) causing acquired immunodefici ency syndrome (AIDS), has suddenly appeared in many countries of the world and brought the slow infection concept forcefully to the attention of the medical profession. The disease problems and the economic effects of slow infections of sheep and goats are increasingly recognized in various coun tries. For the reasons stated above we feel that this book should be useful for veterinarians and physicians alike."

A Seminar in the EEC Programme of Coordination of Research on Animal Reproduction, held at the Station de Physiologie de la Reproduction of the INRA, Nouzilly, France, October 6-7, 1983. Sponsored by the CEC, Directorate-General for Agriculture, Coordination of Agricultural Research.

This book presents a detailed guide to hand-rearing techniques for raising young birds, providing complete coverage of a wide variety of avian species and taxonomic groups for all avian care professionals. Chapters are written by expert rehabilitation, aviculture, and zoo professionals, and include useful references and bibliographies for further reading and research. Each chapter provides valuable information on appropriate intervention, housing, feeding, and care. Hand-Rearing Birds, Second Edition presents 50 chapters, including 12 new chapters on species or groups of species not featured in the previous edition. It also features color photographs that help illustrate many concepts pertinent to birds. This important reference: Offers a detailed guide to hand-rearing techniques including species-specific guides to caring for and raising young birds Covers a wide variety of avian species and taxonomic groups Discusses how to examine a chick to identify problems such as hypothermia, dehydration, injuries, and common diseases, and what to do Combines information on the science and skill needed to successfully hand-rear birds Presents full-color photographs throughout Hand-Rearing Birds, Second Edition is an essential resource for avian rehabilitators, breeders, veterinarians, and zoo staff.

A Seminar in the CEC Programme of Coordination of Research on Animal Pathology, held at the Veterinary Research Laboratories, Belfast, Northern Ireland, Oct. 10-11, 1984. Sponsored by the CEC, Directorate-General for Agriculture, Coordination of Agricultural Research.

A seminar in the Community Programme for the Coordination of Agricultural Research, held in Brussels, Belgium, April 7-9, 1987

The intention of the series Developments in Veterinary Virology is to provide monographs dealing with the major animal viral diseases. Each volume will include the latest achievements in fundamental research and practical applications and should be readable for people from various disciplines and different backgrounds. The multi-author approach provides the best opportunity to keep each chapter at the highest level and makes the composition of the volumes manageable to the editors. This monograph on Avian Leukosis presents comprehensive reviews on the recent history of avian retrovirus research, on epizootiological, virological, pathological aspects, on tumor induction, the immune response to avian retro viruses, virus-cell interactions and on techniques for diagnosis. The volume deals mainly with exogenous avian leukosis virus (ALV) infections, but one chapter is entirely devoted to endogenous avian leukemia virus. Molecular biology aspects are confined to various oncogenes and to lymphoma induction since retroviruses, including those specific for avian species, have recently been described in detail in the Cold Spring Harbor Laboratory series "Molecular Biology of Tumor Viruses." Two chapters are devoted to the practical application of insights obtained from avian leukosis research: influences of AL V infection on production performance and eradication procedures."

Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental interventions. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. The content is structured in six sections. The first deals with ethical, regulatory, and scientific considerations. Chapters in this section include US and international regulatory considerations, and optimization of anesthesia and analgesia. Part two is dedicated to the principles of anesthesia and analgesia with chapters covering topics in a non-species-specific way, but with a slant towards laboratory animals, including relevant pharmacology of the agents. Part three covers Anesthetic equipment and monitoring. Section four deals with periprocedural care including dedicated chapters to the assessment and management of pain in laboratory species. Part five provides practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species. Part six closes the book with special topics covering management of chronic pain, fetus and neonate interventions, considerations for in-vivo imaging and the study of pain. Anesthesia and Analgesia in Laboratory Animals is the complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs, and researchers who utilize animals in biomedical research.

Veterinary Image-Guided Interventions is the only book dedicated to interventions guided by imaging technology. Written and edited by leading experts in the field, interventional endoscopy, cardiology, oncology and radiology are covered in detail. Chapters include the history and background of the procedures, patient work-up, equipment lists, detailed procedural instructions, potential complications, patient follow-up protocols, and expected outcomes. Split into body systems, the technical aspects of each procedure are presented using highly illustrated step-by-step guides. Veterinary Image-Guided Interventions is a must-have handbook for internists, surgeons, cardiologists, radiologists, oncologists and criticalists, and for anyone interested in cutting-edge developments in veterinary medicine. Key features include: * A highly practical step-by-step guide to image-guided procedures * Relevant to a wide range of veterinary specialists. * Written and edited by respected pioneers in veterinary image-guided procedures * A companion website offers videos of many procedures to enhance the text

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

In this issue of Veterinary Clinics: Small Animal Practice, guest editors Drs. Thomas K. Graves and Chen Gilor bring their considerable expertise to the topic of Diabetes Mellitus in Cats and Dogs. Top experts in the field cover key topics such as hypoglycemia and autonomic failure in dogs; anesthetic considerations in dogs and cats with diabetes mellitus; insulin therapy in dogs and cats; hypersomatotropism and other causes of insulin resistance in cats; and more. Contains 14 relevant, practice-oriented topics including diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome in dogs and cats; diabetes mellitus and the kidneys; continuous glucose monitoring in dogs and cats: applying new technology to an old problem; the role of nutrition in diabetes mellitus therapy; the future of diabetes therapies: ultra-long-acting insulin, smart insulin, novel GLP-1 analogs, SGLT-2 inhibitors and beta cell replacement therapy; and more. Provides in-depth clinical reviews on diabetes mellitus in cats and dogs, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Horses perceive the world differently from humans because their senses developed differently through evolution to cope with different ways of living and surviving. Horses are essentially prey/flight animals. The horse's senses therefore determine how the world appears to him and how he reacts to it. As the horse's perception and understanding are very different to ours sometimes their reaction to events and their surroundings seem strange to us. In this book the author compares the horses sensory organs with those of humans to avoid misunderstandings as lack of knowledge can lead to many problems when dealing with horses. The five senses are covered in this book: hearing, sight, smell, taste and touch. Each section explains how the horses' sense works and then this is related to care, behavior and riding, explaining why some practices are appropriate and why some are not. The behavioral aspect of dealing with horses is emphasized throughout. The author is founder of the Equine Behaviour Forum and author of over 40 books on equine topics. She has an HNC in Equine Sciences and Management, is a Classical Riding Club Gold Award Holder and classical trainer, an equine shiatsu practitioner, and an Associate Member of the International Society for Equitation Science. This book is useful for all horse owners, horse breeders and trainers who wish to gain a better understanding of how the horse's senses function, and for veterinary students and practitioners.

Proceedings of a Meeting held at the University of Surrey, Guildford, U.K., September 15-17, 1981