This issue of Clinics in Laboratory Medicine will focus on Veterinary Medicine. Article topics include acute phase protein testing, glucose monitoring in dogs and cats, equine neonatal intensive care, animal platelet disorders, canine lymphoma, reptile hematology, infectious diseases in birds, rare and endangered wildlife, and metabolic disease testing.

The equine practitioner will find this comprehensive issue packed with useful, practical information on endocrine diseases. Topics include disorders of calcium and phosphate metabolism, endocrinology of the neonate energy metabolism, endocrine dysregulation in critically ill foals and horses, magnesium disorders, equine metabolic syndrome, pars intermedia dysfunction (Cushing's disease), disorders of the hypothalamus-pituitary-adrenal gland axis, evaluation of the hypothalamus-pituitary-adrenal gland axis, disorders of the thyroid gland, endocrine response during exercise, hyperlipemia, anhidrosis, diabetes insipidus, ergopeptine alkaloids (fescue toxicosis) and equine pregnancy, and much more

Guest editors Mark Acierno and Mary Labato highlight important areas in kidney failure and renal replacement therapies for all small animal practitioners. Topics include continuous renal replacement therapy, intermittent hemodialysis/peritoneal dialysis, acute kidney injury, chronic kidney disease, protein losing nephropathy, hypertension in kidney disease, intermittent hemodialysis, equipment commonly used in veterinary dialysis/vascular access, anticoagulation in intermittent hemodialysis, urea kinetics and dialysis prescriptions, removal of toxins and drugs, nutrition in the renal failure/dialysis patient, dialysate, water quality and testing, and much more

Cardiology of the Horse is a multi-author, contemporary reference on equine cardiology. The first section reviews the physiology, pathophysiology and pharmacology of the equine cardiovascular system. The second section describes diagnostic methods from basic to specialist examination skills and the third section addresses the investigation and management of common clinical problems using a problem-orientated approach. Suitable for students, general and specialist practitioners and teachers. An up-to-date account of current clinical practice in equine cardiology covering: recent developments in research and practice problem-orientated approaches helpful to both general and specialist practitioners clinical management of specific groups from foals and racehorses to geriatric patients cardiac problems related to exercise, anaesthesia and intensive care A superb companion DVD of clinical cases with extensive footage combining theory and clinical practice: echocardiograms heart sounds and murmurs ECGs radiography pathology Extensive linking of text to DVD, integrating fundamental principles and diagnostic data with information on clinical management of specific problems.

A current review of important internal medicine topics for the exotic animal practitioner Articles will review metabolic bone disease, avian hepatic disorders, avian female reproductive disorders, proventricular dilatation disease, avian renal disorders, ferret neoplasia, amphibian internal disorders, koi reproductive disorders, thyroid tumors and lymphadenopathies in guinea pigs, reproductive reptilian disorders, disseminated idiopathic myositis in ferrets, gastric stasis in rabbits, and much more

A comprehensive review of pain management and anesthesia for the equine practitioner. Articles include opioids as pain therapy, alpha-2 agonists as pain therapy, anti-inflammatories as pain therapy, local anesthetics, epidural and regional drugs, NMDA inhibitors and behavior modifiers, treatment of visceral pain and colic, treatment of osteoarthritic and chronic pain syndromes, and much more!

An ophthalmology primer for the food animal practitioner Articles include examination techniques and therapeutic regimens for the ruminant eye, surgical techniques, infectious bovine keratoconjunctivitis, congenital abnormalities, listerial keratoconjunctivitis and uveitis, ophthalmology of small camelids, squamous cell carcinoma, and more

A current, comprehensive review of infectious diseases for the small animal practitioner Topics will include: canine leptospirosis, canine parvovirus, lyme disease, ehrlichia/anaplasma, canine influenza, molecular diagnostic assays for infectious diseases in cats, bartonella, feline hemotropic mycoplasma, antifungal treatment, antiviral therapy for feline herpes virus infections, canine babesiosis, and more

Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis. However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds. Their existence explains many of the enigmas of microbial infection and a better grasp of the process may well serve to establish a different approach to infection control and management. Biofilms and their associated complications have been found to be involved in up to 80% of all infections. A large number of studies targeted at the bacterial biofilms have been conducted, and many of them are referred to in this book, which is the first of its kind. These clinical observations emphasize the importance of biofilm formation to both superficial and systemic infections, and the inability of current antimicrobial therapies to 'cure' the resulting diseases even when the in vitro tests suggest that they should be fully effective. In veterinary medicine the concept of biofilms and their role in the pathogenesis of disease has lagged seriously behind that in human medicine. This is all the more extraordinary when one considers that much of the research has been carried out using veterinary species in experimental situations. The clinical features of biofilms in human medicine is certainly mimicked in the veterinary species but there is an inherent and highly regrettable indifference to the failure of antimicrobial therapy in many veterinary disease situations, and this is probably at its most retrograde in veterinary wound management. Biofilms and Veterinary Medicine is specifically focused on discussing the concerns of biofilms to health and disease in animals and provides a definitive text for veterinary practitioners, medical and veterinary students, and researchers.

Articles include: Human Insulin Analogs in Feline Diabetes; Diabetes Emergencies in Small Animals; Management of Obesity in Dogs; Trilostane Therapy; Recent Advances in Diagnosis of Cushing's Syndrome in Dogs; Primary Hyperaldosteronism in Cats; Insulin Resistance in Dogs; Insulin Resistance in Cats; Endocrine Hypertension; Atypical Cushing's; and The Endocrinology of Obesity.

A comprehensive review of bovine respiratory disease for the food animal practitioner Topics will include control methods for bovine respiratory disease for cow-calf, stocker and feedlot cattle, metaphylaxis, pathology, immunology, mycoplasma, bovine viral diarrhea virus, bovine respiratory syncytial virus, infectious bovine rhinotracheitis, bovine respiratory coronavirus, bacteriology of bovine respiratory disease, atypical interstitial pneumonia, diagnostics for bovine respiratory disease, and much more

A comprehensive review of cardiology for the small animal practitioner Articles will focus on advanced techniques in echocardiography, use of natiuretic peptides in the management of canine patients with heart disease, use of natiuretic peptides in the management of feline patients with heart disease, current use of pimobendan in canine patients with heart disease, canine mitral valve disease, infective endocarditis, interventional catheterization for congenital heart disease, pulmonary hypertension, feline hypertrophic cardiomyopathy, feline arrhythmias, surgery for cardiac disease, gene therapy for cardiac disease, and much more

Articles include: General Introduction and Equipment Overview; Overview of Avian Endoscopy; Overview of Reptile Endoscopy; Endoscopic Gender Determination in Chelonians; Reptile Ovariectomy; Overview of Exotic Mammal Endoscopy; Overview of Fish Endoscopy; Endoscopic Intubation of Exotic Companion Mammals; Shark and Ray Endoscopy; and Endoscope-Assisted Ovariectomy in Chelonia.

Articles include: Review of Basic Immunology and Hypersensitivity Reactions; Diagnostic Assays for Immunologic Diseases, Immunomodulators, Immunostimulants and Immunotherapies; Canine and Feline Vaccines; Adverse Events in Small Animals; Immune-Mediated Diseases; Transfusion Medicine; Transplantation in Small Animals; Cancer Immunology; Secondary Immunodeficiencies Due to Infections Diseases; Noninfectious Causes of Immunosuppression; and Primary Immunodeficiences.

Articles include: The Anatomy and Physiology of the Lamellar; Dermal-Epidermal Interface; Carbohydrate Alimentary Overload Laminitis; Events in the Hindgut; Therapeutic Hypothermia (cryotherapy) to Prevent and Treat Acute Laminitis; Acute Laminits: Supportive Medical Therapy; First Aid for the Foot: Therapeutic and Mechanical Support; Serial Venography after Carbohydrate-Induced Laminitis; Venography and Its Clinical Application in North America; Chronic Laminitis: Strategic Hoof Wall Resection; The Laminar Wedge of Chronic Laminitis; Lysis of the Distal Phalanx in Chronic Laminitis; Chronic Laminitis Foot Support: Clogs, Homecare for the Chronic Laminitis Case; The Pharmacological Basis for the Treatment of Developmental and Acute Laminitis; and Black Walnut Extract Laminitis: An Inflammatory Model.

The complex and fascinating subject of endocrinology can often seem rather daunting for non-specialists. For practising endocrinologists too, maintaining a broad overview of the subject can be a major task. Laboratory Animal Endocrinology has been written with both these audiences in mind. Focusing on the species regularly used in experimental studies (including rodents, dogs and monkeys), each chapter presents a wealth of information on hormone structure, synthesis, secretion, receptors, second messengers and their actions, and considers the various physiological and pharmacological processes which may be involved in hormonal regulation. Interspecies’ differences in hormonal structure, metabolism and interactions with drugs and other chemicals are particularly important to toxicologists and in drug safety evaluation. Laboratory Animal Endocrinology also explores these areas of research and provides much-needed support for the interpolation of endocrine data from one test species to another and to humans. The book is not intended exclusively for toxicologists however, but will prove indispensable for all those working with laboratory animals.

Articles include: Geriatric Medicine in Psittacines; The Aging Raptor; The Ancient Rat; Geriatric Medicine of the Guinea Pig and Chinchilla; Geriatric Medicine of the Rabbit; Geriatric Medicine of the Reptile; Geriatric Medicine of Fresh Water Fish; Pathology of the Geriatric Bird; Rehabilitation of the Exotic Patient; and The Geriatric Ferret.

Articles include: Update on Bovine Respiratory Coronavirus; Field Necropsy Techniques and Proper Specimen Submission for Investigation of Emerging Infectious Diseases of Food Animals; Bovine Viral Diarrhea Virus: Global Status; Role of Bovine Herpesvirus-4 in Disease; Role of Wildlife in Diseases of Cattle: Brucellosis, Bovine Viral Diarrhea and TB; Climate Changes and Arthropod-borne Diseases of Cattle Including Bluetongue, Cryptosporidiosis in Cattle, E. Coli and Salmonella Infections in Cattle; Bovine Trichomonas Fetus; Diagnosis and Antibiotic Resistance; Investigations (MRSA) in Food Animal Bacterial Infections; Bovine Brucellosis; Bovine Pasteurellosis and Other Bacterial Infections of the Respiratory Tract; and Infectious Bovine Keratoconjuctivitis.

A complete primer on practice management for the equine practitioner! Topics include current economic trends, transitioning from veterinary school to private practice, customer service, gender shifts, design of an ambulatory practice, equine practice evaluations and sale transactions, mergers and acquisitions, marketing, employee issues, medical record keeping, ethics in equine practice, hospital design, and much more!

A comprehensive update on parasitology for the small animal practitioner! Topics will include fleas and ticks; mites and lice; giardia and tritrichomonas; toxoplasma gondii and intestinal coccidia; babesia, cytoxzoan, and hepatozoan; heartworms; intestinal nematodes; flukes and tapeworms; lungworms and other extraintestinal nematodes, and much more!

A current, comprehensive issue on management of colic in horses. Topics include equine gastric ulcer syndrome, impactions of the small and large intestine, enterolithiasis, antiendotoxin therapies, inflammatory bowel disease and chronic colic, colitis in hospitalized horses, parasitism, coagulopathies in horses with colic, post-operative ileus and prokinetic agents, post-operative complications, prognostic indicators and survival, feasibility and creation of an international audit and database of equine colic surgery, and much more

The latest information on bacterial and parasitic diseases in exotic pet animals for the exotic animal veterinarian. Species to be covered include passerines, psittacines, anseriformes, birds of prey, ferrets, rabbits, primates, fish, and more.

The latest in imaging techniques for the small animal practitioner. This issue is divided into 4 sections: Radiology (covering principles of digital imaging, comparing types of digital capture, digital imaging artifacts, PACS and image storage, non-traditional interpretation of lung patterns); Ultrasound (GI tract, right lateral intercostal space, thorax); Computed Tomography (portosystemic shunts); and Nuclear Medicine (imaging of portosystemic shunts).

A complete primer on endoscopy for the small animal practitioner! Topics will include flexible and rigid endoscopic equipment and specialized instrumentation, anesthesia, diagnostic rigid Endoscopy, flexible gastrointestinal endoscopic procedures, airway evaluation and flexible endoscopic procedures, gastrointestinal laparoscopic and laparoscopic assisted procedures, advanced laparoscopic procedures, diagnostic thoracoscopy, complications, and much more!