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Histophilus somni - Biology, Molecular Basis of Pathogenesis, and Host Immunity (Hardcover, 1st ed. 2016)
Loot Price: R2,864
Discovery Miles 28 640
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Histophilus somni - Biology, Molecular Basis of Pathogenesis, and Host Immunity (Hardcover, 1st ed. 2016)
Series: Current Topics in Microbiology and Immunology, 396
Expected to ship within 10 - 15 working days
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This volume reviews the current understanding of the taxonomy,
disease syndromes, genetics, biology, and pathogenic factors of
Histophilus somni, as well as the host immune response to this
pathogen. H. somni is one of the most important bacterial pathogens
in cattle and other ruminants, and its virulence factors are highly
conserved with Haemophilus influenzae and other members of the
Pasteurellaceae. H. somni has been recognized as a major cause of
thrombotic meningoencephalitis, respiratory disease syndromes,
myocarditis, reproductive disease syndromes, polyarthritis,
mastitis, ocular disease, and septicemia. The only known habitats
of H. somni are the mucosal surfaces of ruminants, making this
bacterium an opportunistic pathogen. Although it is capable of
causing inflammation at systemic sites and is toxic to epithelial
and phagocytic cells, the bacterium's wide array of virulence
factors act primarily as a defense against, or to escape
recognition from, host innate and adaptive immunity.
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