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Books > Medicine > Other branches of medicine > Pharmacology
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Mediators and Drugs in Gastrointestinal Motility II - Endogenous and Exogenous Agents (Paperback, Softcover reprint of the original 1st ed. 1982)
Loot Price: R3,011
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Mediators and Drugs in Gastrointestinal Motility II - Endogenous and Exogenous Agents (Paperback, Softcover reprint of the original 1st ed. 1982)
Series: Handbook of Experimental Pharmacology, 59 / 2
Expected to ship within 10 - 15 working days
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This volume places more emphasis on endogenous mediators of gut
motility than on drugs used to treat patients with deranged
motility. In this respect it resembles most other books on
gastroenterology, for while only a relatively small number of drugs
are really useful for a rational therapy, a tremendous amount of
data is available on neural and hormonal factors regulating the
motility of the alimentary canal. Moreover, it must be considered
that some of the drugs which can routinely be employed to modify
deranged motility of the digestive system are represented by pure
or slightly modified endogenous compounds (e. g. , cholecystokinin,
its C terminal octapeptide and caerulein), and it is easy to
foresee that their number is destined to increase in the near
future. Other drugs are simply antagonists of physiological
substances acting on specific receptors (e. g. , histamine H
-blockers 2 and opioid compounds). The real explosion of research
in this field and the extreme specialization often connected with
the use of very sophisticated techniques and methodologies would
probably have required a larger number of experts to cover some
very specific fields from both an anatomical (lower esophageal
sphincter, stomach, pylorus, small and large intestine) and a
biochemical (hormones, candidate hormones, locally active
substances, neurotransmitters etc. ) point of view.
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