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Current Topics in Extrapyramidal Disorders (Paperback, Softcover reprint of the original 1st ed. 1980)
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Current Topics in Extrapyramidal Disorders (Paperback, Softcover reprint of the original 1st ed. 1980)
Series: Journal of Neural Transmission. Supplementa, 16
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The scientific work of Walther Birkmayer is grounded on his ability
to turn what was often a mass of clinical details into the basis
for a hypothesis for a new therapeutic approach toward solving the
problems of a patient's illness. Birkmayer first became known when,
during the Second World War, he built up a clinic for brain
injuries in Vienna, in which over 3000 patients were treated. The
study of changes in the autonomic functions of the nervous system
in these patients as well as the problems of rehabilitation were
published in a monograph, "Hirn- verletzungen". Consequently, this
was his major scientific interest during the post-war years. His
book, "Klinik und Therapie der vegetativen Funktionsstorungen"
published with W. Winkler, brought Birkmayer recognition in the
German-speaking world. In 1954 he took over the Neurological
Department of the Geriatric Hospital of Vienna in Lainz, where he
remained until his retirement in 1975. International acclaim
followed his breakthrough with the clinical application of L-DOPA
in Parkinson's disease. Birkmayer, as a strong adherent to the
scientific interpretation of neurological and psychiatric disease,
has encouraged multidisciplinary research. This is reflected in his
establishment of the former Ludwig Boltzmann- Institute of
Neurochemistry, in which pharmacological, biochemical and
histopathological research into neuropsychiatric diseases was
performed under one roof. Further to his initial work on L-DOPA,
Birkmayer has been in the forefront of supplementary parkinsonian
therapy using enzyme inhibitors: benserazide in 1967, unselective
monoamine oxidase inhibitors in 1962 and deprenyl in 1975.
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