Antithrombotics - Pathophysiological Rationale for Pharmacological Interventions (Hardcover)

1. Platelet activation and aggregation: rationale for combining antithrombotic drugs.- 2. Role of nitric oxide in endothelial cell - platelet interactions.- 3. Platelets and megakaryocytes in vascular disease.- 4. Thrombosis in relation to atherosclerosis.- 5. Pharmacological inhibition of the ADP-GP IIb/IIIa-fibrinogen pathway of platelet aggregation.- 6. Calcium fluxes in platelets and endothelial cells, mechanisms and functional significance.- 7. Inhibition of platelet function by cyclic nucleotides and cyclic nucleotide-dependent protein kinases.- 8. Pharmacological modification of platelet-derived cyclooxygenase product formation and its consequences for platelet-vessel wall interactions.- 9. Antithrombotics and the lipoxygenase pathway.- 10. Pathological expressions of platelet-vessel wall interactions: implications of serotonin.- 11. The involvement of PAF in thrombotic events.- 12. Prostaglandins and -analogs in the treatment of platelet-vessel wall interaction.- 13. Adjuvant agents to enhance and sustain reperfusion with t-PA: studies in experimental dog models.- 14. Effect of dietary marine lipids on (anti-)thrombotic mechanisms.

General

Imprint:	Kluwer Academic Publishers
Country of origin:	United States
Series:	Developments in Cardiovascular Medicine
Release date:	September 1991
First published:	September 1991
Editors:	A.G. Herman
Dimensions:	230mm (L)
Format:	Hardcover
Pages:	272
ISBN-13:	978-0-7923-1413-4
Categories:	Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
LSN:	0-7923-1413-1
Barcode:	9780792314134

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